iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017758

Ensembl Protein ID

Bra030388.1-P

UniProt Accession

M4ENL8; M4ENL8_BRARP

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra030388	Bra030388.1	Bra030388.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-35	118.5	192	232
UBD/Beta-Prp	1.50e-66	225.6	16	297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 192  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 232
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           k+ +++++++++cv+ +p +++++++ ++gt+ +w+++t+ + +s++  + +v++ kf+ ++++ v g++D+ i+v++++t + v ++++h+d+++
   Q: 16   KKKFAQRSERVKCVDLHPTEPWILASLYSGTLCIWNYQTQVMAKSFEVTDLPVRSAKFIARKQWVVAGADDMYIRVYNYNTMDKVKVFEAHSDYIR 111
           5667788999************************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsn 191
           +++++p+  +++s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++     +
   Q: 112  CVAVHPTLPYVLSSSDDMLIKLWDWEKGWACTQIFEGHSHYVMQVTLNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGD 206
           *****************************9999*********************************************98.*********644455 PP
   S: 192  gkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvl 282
           +++l++gs+d t k+wd+qt++cv+tl ght nv+ v f+p+  ++++gs+Dg++riW  ++  l +tl++  ++v+++ +++ +++v++ 
   Q: 207  KPYLITGSDDHTAKVWDYQTKSCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYIKSSRRVVIG 297
           5******************************************************************************997777777654 PP

Organism

Brassica rapa

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MAEGSGIVSP LRLEIKKKFA QRSERVKCVD LHPTEPWILA SLYSGTLCIW NYQTQVMAKS 60
FEVTDLPVRS AKFIARKQWV VAGADDMYIR VYNYNTMDKV KVFEAHSDYI RCVAVHPTLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAAG GATCTGGAAT TGTTTCAGTT GGGTTTTAGG ATTTTGGTAA AGTTTGTGTG 60
TTTTGAATTC ACGAATGTGT GTTAGTACTG ACTGTTTACT GGTTTCTCTG TCTTTTTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002154	Ailuropoda melanoleuca	60.55	0.00e+00	1109.00
IUUC-Atr-003090	Amborella trichopoda	76.48	0.00e+00	1467.00
IUUC-Apl-003976	Anas platyrhynchos	60.19	0.00e+00	1110.00
IUUC-Aca-004301	Anolis carolinensis	60.26	0.00e+00	1110.00
IUUC-Aly-006508	Arabidopsis lyrata	93.28	0.00e+00	1726.00
IUUC-Ath-007635	Arabidopsis thaliana	92.22	0.00e+00	1720.00
IUUC-Afl-008535	Aspergillus flavus	52.60	0.00e+00	847.00
IUUC-Ang-009654	Aspergillus niger	55.45	0.00e+00	804.00
IUUC-Ame-010922	Astyanax mexicanus	56.02	0.00e+00	969.00
IUUC-Bgr-012249	Blumeria graminis	51.20	0.00e+00	878.00
IUUC-Bci-013866	Botrytis cinerea	53.42	0.00e+00	889.00
IUUC-Bdi-015046	Brachypodium distachyon	77.44	0.00e+00	1489.00
IUUC-Bol-015731	Brassica oleracea	96.78	0.00e+00	1767.00
IUUC-Cel-018387	Caenorhabditis elegans	53.89	0.00e+00	980.00
IUUC-Cja-019145	Callithrix jacchus	60.43	0.00e+00	1110.00
IUUC-Cfa-020564	Canis familiaris	60.55	0.00e+00	1110.00
IUUC-Cpo-022201	Cavia porcellus	60.55	0.00e+00	1110.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	64.85	0.00e+00	1089.00
IUUC-Cne-026986	Cryptococcus neoformans	49.58	0.00e+00	865.00
IUUC-Cme-027219	Cyanidioschyzon merolae	50.36	0.00e+00	882.00
IUUC-Dse-031268	Dothistroma septosporum	51.89	0.00e+00	879.00
IUUC-Dme-031791	Drosophila melanogaster	56.93	0.00e+00	1004.00
IUUC-Eca-034180	Equus caballus	59.17	0.00e+00	1069.00
IUUC-Eeu-035086	Erinaceus europaeus	49.27	2.00e-125	443.00
IUUC-Fca-036265	Felis catus	60.55	0.00e+00	1110.00
IUUC-Fal-037202	Ficedula albicollis	59.93	0.00e+00	1066.00
IUUC-Fox-037711	Fusarium oxysporum	53.30	0.00e+00	845.00
IUUC-Fso-038268	Fusarium solani	52.91	0.00e+00	850.00
IUUC-Gmo-039046	Gadus morhua	60.82	0.00e+00	1097.00
IUUC-Ggr-039863	Gaeumannomyces graminis	52.63	0.00e+00	873.00
IUUC-Gga-041112	Gallus gallus	60.55	0.00e+00	1114.00
IUUC-Gma-044126	Glycine max	86.07	0.00e+00	1629.00
IUUC-Ggo-044984	Gorilla gorilla	60.43	0.00e+00	1109.00
IUUC-Hsa-046698	Homo sapiens	60.55	0.00e+00	1110.00
IUUC-Hvu-047669	Hordeum vulgare	87.57	0.00e+00	687.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	61.62	0.00e+00	1107.00
IUUC-Lch-050473	Latimeria chalumnae	61.43	0.00e+00	1108.00
IUUC-Loc-052675	Lepisosteus oculatus	59.65	0.00e+00	1114.00
IUUC-Laf-053757	Loxodonta africana	60.52	0.00e+00	1105.00
IUUC-Mcc-054859	Macaca mulatta	60.43	0.00e+00	1110.00
IUUC-Meu-056174	Macropus eugenii	52.93	2.00e-112	399.00
IUUC-Mtr-058618	Medicago truncatula	86.30	0.00e+00	1606.00
IUUC-Mvi-060240	Microbotryum violaceum	51.71	0.00e+00	891.00
IUUC-Mmr-061261	Microcebus murinus	60.55	0.00e+00	1110.00
IUUC-Mdo-062076	Monodelphis domestica	60.66	0.00e+00	1114.00
IUUC-Mmu-063324	Mus musculus	60.55	0.00e+00	1110.00
IUUC-Mac-064636	Musa acuminata	80.07	0.00e+00	1514.00
IUUC-Mpu-065961	Mustela putorius furo	60.55	0.00e+00	1109.00
IUUC-Mlu-067059	Myotis lucifugus	59.72	0.00e+00	1097.00
IUUC-Ncr-068659	Neurospora crassa	52.32	0.00e+00	889.00
IUUC-Nle-069034	Nomascus leucogenys	60.43	0.00e+00	1109.00
IUUC-Oan-073416	Ornithorhynchus anatinus	60.05	0.00e+00	1054.00
IUUC-Ocu-074522	Oryctolagus cuniculus	61.38	0.00e+00	1103.00
IUUC-Oba-075760	Oryza barthii	78.35	0.00e+00	1481.00
IUUC-Obr-076201	Oryza brachyantha	79.87	0.00e+00	1493.00
IUUC-Ogl-077450	Oryza glaberrima	79.83	0.00e+00	1508.00
IUUC-Ogu-078994	Oryza glumaepatula	79.19	0.00e+00	1481.00
IUUC-Oni-082324	Oryza nivara	78.93	0.00e+00	1480.00
IUUC-Opu-083400	Oryza punctata	76.70	0.00e+00	1454.00
IUUC-Oru-084829	Oryza rufipogon	79.06	0.00e+00	1483.00
IUUC-Ola-087245	Oryzias latipes	61.06	0.00e+00	1104.00
IUUC-Olu-087655	Ostreococcus lucimarinus	66.29	0.00e+00	1141.00
IUUC-Oga-088163	Otolemur garnettii	58.46	0.00e+00	1057.00
IUUC-Oar-089842	Ovis aries	60.55	0.00e+00	1111.00
IUUC-Ptr-090501	Pan troglodytes	60.43	0.00e+00	1110.00
IUUC-Pan-092011	Papio anubis	60.43	0.00e+00	1110.00
IUUC-Pma-094695	Petromyzon marinus	58.63	0.00e+00	984.00
IUUC-Ppa-095638	Physcomitrella patens	76.81	0.00e+00	1398.00
IUUC-Pop-099634	Populus trichocarpa	85.59	0.00e+00	1592.00
IUUC-Pca-100965	Procavia capensis	59.60	0.00e+00	1073.00
IUUC-Ppe-101470	Prunus persica	85.70	0.00e+00	1635.00
IUUC-Pgr-103453	Puccinia graminis	52.75	0.00e+00	892.00
IUUC-Ptt-103868	Puccinia triticina	52.75	0.00e+00	890.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.10	0.00e+00	748.00
IUUC-Sha-106905	Sarcophilus harrisii	60.66	0.00e+00	1113.00
IUUC-Sly-111775	Solanum lycopersicum	82.55	0.00e+00	1572.00
IUUC-Stu-112906	Solanum tuberosum	81.75	0.00e+00	1431.00
IUUC-Sbi-113801	Sorghum bicolor	78.75	0.00e+00	1477.00
IUUC-Sre-115040	Sporisorium reilianum	52.43	0.00e+00	894.00
IUUC-Ssc-115593	Sus scrofa	60.43	0.00e+00	1108.00
IUUC-Tgu-117239	Taeniopygia guttata	60.43	0.00e+00	1112.00
IUUC-Tru-118025	Takifugu rubripes	60.07	0.00e+00	1102.00
IUUC-Tni-120142	Tetraodon nigroviridis	59.91	0.00e+00	1099.00
IUUC-Tca-121613	Theobroma cacao	86.15	0.00e+00	1640.00
IUUC-Tre-122072	Trichoderma reesei	52.29	0.00e+00	883.00
IUUC-Tme-127041	Tuber melanosporum	53.07	0.00e+00	902.00
IUUC-Tbe-127770	Tupaia belangeri	59.85	0.00e+00	887.00
IUUC-Ttr-129294	Tursiops truncatus	60.31	0.00e+00	1106.00
IUUC-Vvi-131689	Vitis vinifera	87.30	0.00e+00	1578.00
IUUC-Zma-135867	Zea mays	79.17	0.00e+00	1506.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence