iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049265

Ensembl Protein ID

CAY67546

UniProt Accession

C4QWC3; C4QWC3_KOMPG

Genbank Protein ID

CAY67546.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-1_0181

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-1_0181	CAY67546	CAY67546

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-30	100.7	186	221
UBD/Beta-Prp	1.70e-66	222.5	5	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf...sd.tllvsGsdDgtikvWDlrtgvll 36
           +v+ +++   sd ++++++sdD+tikvWD+ t  ++
   Q: 186  GVNYVEYyaqSDkPYIITSSDDKTIKVWDYQTKSCV 221
           58889888*9999****************9998775 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           ik+ +++++++++ ++f+p++++++t+ ++g+ ++w+++t +l++++   + +v+a +f+ ++++ v gs+D  i+v++++tg+ v  +++h d+++++++
   Q: 5    IKKTFSARSDRVKGIDFHPSEPWVLTTLYSGKAEIWSYETSTLVKTFDITNVPVRAGRFIARKNWVVLGSDDFQIRVYNYNTGEKVAQFEAHPDYIRAIAV 105
           567789999******************************************************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsl 200
           +p+ +++++ s+d+ i++w+++++++le++++gh++ v++v+++p++ n ++s+slDr v++W+l       tl    t+ v+ +++  ++  +++++ s+
   Q: 106  HPTLSYVLTCSDDSKIKLWNWDHNWKLEQVFEGHQHYVMSVAFNPKDpNTFASASLDRSVKIWSLGLSVPNFTLLAHETKGVNYVEYYAQSdkPYIITSSD 206
           *****************************************************************9999999999999********6555555******** PP
   S: 201  dgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkne 298
           d+t+k+wd+qt++cv  l+gh +nv+   f+p+  ++vsgs+D +i++W+  + +l k+l++  ++ +sv++   ++++lv++++d    +++l+ ++
   Q: 207  DKTIKVWDYQTKSCVAVLEGHISNVSFAVFHPELPLIVSGSEDATIKVWNANTYKLEKSLNYGLERAWSVSF--RKGSNLVAVGFDAGHVVLQLADDK 302
           ************************************************************************..889999999999988888887666 PP

Organism

Komagataella pastoris

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDIKKTFS ARSDRVKGID FHPSEPWVLT TLYSGKAEIW SYETSTLVKT FDITNVPVRA 60
GRFIARKNWV VLGSDDFQIR VYNYNTGEKV AQFEAHPDYI RAIAVHPTLS YVLTCSDDSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGATTAG ATATCAAAAA GACTTTTTCT GCACGGTCAG ATCGTGTGAA AGGAATTGAC 60
TTTCATCCAT CTGAGCCCTG GGTGCTAACG ACTCTGTACA GTGGAAAGGC TGAAATATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0167--Capsid protein
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0946--Virion
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005634--C:nucleus
GO:0019028--C:viral capsid
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

ppa:PAS_chr1-1_0181

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	44.75	0.00e+00	709.00
IUUC-Aml-002154	Ailuropoda melanoleuca	49.19	0.00e+00	863.00
IUUC-Atr-003090	Amborella trichopoda	52.27	0.00e+00	836.00
IUUC-Apl-003976	Anas platyrhynchos	47.02	0.00e+00	866.00
IUUC-Aca-004301	Anolis carolinensis	49.56	0.00e+00	867.00
IUUC-Aly-005643	Arabidopsis lyrata	50.75	0.00e+00	823.00
IUUC-Ath-007630	Arabidopsis thaliana	50.87	0.00e+00	837.00
IUUC-Ago-007914	Ashbya gossypii	54.95	0.00e+00	930.00
IUUC-Acl-008237	Aspergillus clavatus	56.53	0.00e+00	957.00
IUUC-Afl-008535	Aspergillus flavus	55.92	0.00e+00	909.00
IUUC-Afu-008845	Aspergillus fumigatus	56.90	0.00e+00	938.00
IUUC-Ani-009135	Aspergillus nidulans	57.56	0.00e+00	934.00
IUUC-Ang-009654	Aspergillus niger	59.27	0.00e+00	863.00
IUUC-Aor-009939	Aspergillus oryzae	55.11	0.00e+00	972.00
IUUC-Ate-010355	Aspergillus terreus	56.40	0.00e+00	936.00
IUUC-Ame-010922	Astyanax mexicanus	46.40	0.00e+00	753.00
IUUC-Bgr-012249	Blumeria graminis	55.60	0.00e+00	923.00
IUUC-Bta-013579	Bos taurus	50.28	0.00e+00	791.00
IUUC-Bci-013866	Botrytis cinerea	56.42	0.00e+00	915.00
IUUC-Bdi-015046	Brachypodium distachyon	50.56	0.00e+00	843.00
IUUC-Bol-016012	Brassica oleracea	52.43	0.00e+00	850.00
IUUC-Bra-016617	Brassica rapa	50.00	0.00e+00	819.00
IUUC-Cel-018387	Caenorhabditis elegans	47.14	0.00e+00	827.00
IUUC-Cja-019145	Callithrix jacchus	49.32	0.00e+00	863.00
IUUC-Cfa-020564	Canis familiaris	49.19	0.00e+00	862.00
IUUC-Cpo-022201	Cavia porcellus	49.32	0.00e+00	864.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	49.81	0.00e+00	783.00
IUUC-Csa-023383	Chlorocebus sabaeus	53.87	0.00e+00	683.00
IUUC-Cho-024454	Choloepus hoffmanni	47.55	0.00e+00	751.00
IUUC-Cin-025681	Ciona intestinalis	48.38	0.00e+00	800.00
IUUC-Csv-026012	Ciona savignyi	50.58	0.00e+00	796.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.92	0.00e+00	834.00
IUUC-Cne-026986	Cryptococcus neoformans	51.99	0.00e+00	892.00
IUUC-Cme-027219	Cyanidioschyzon merolae	43.55	0.00e+00	756.00
IUUC-Dre-027846	Danio rerio	49.69	0.00e+00	870.00
IUUC-Dor-030462	Dipodomys ordii	48.65	0.00e+00	703.00
IUUC-Dse-031268	Dothistroma septosporum	54.58	0.00e+00	943.00
IUUC-Dme-031791	Drosophila melanogaster	46.97	0.00e+00	811.00
IUUC-Ete-033166	Echinops telfairi	48.12	1.00e-164	571.00
IUUC-Eca-034180	Equus caballus	47.76	0.00e+00	822.00
IUUC-Eeu-035086	Erinaceus europaeus	38.50	6.00e-86	310.00
IUUC-Fca-036265	Felis catus	49.19	0.00e+00	862.00
IUUC-Fal-037202	Ficedula albicollis	48.58	0.00e+00	819.00
IUUC-Fox-037711	Fusarium oxysporum	56.65	0.00e+00	869.00
IUUC-Fso-038268	Fusarium solani	56.61	0.00e+00	871.00
IUUC-Gmo-039046	Gadus morhua	49.32	0.00e+00	864.00
IUUC-Ggr-039863	Gaeumannomyces graminis	57.27	0.00e+00	900.00
IUUC-Gga-041112	Gallus gallus	49.56	0.00e+00	868.00
IUUC-Gac-041733	Gasterosteus aculeatus	46.78	0.00e+00	825.00
IUUC-Gma-044333	Glycine max	51.66	0.00e+00	845.00
IUUC-Ggo-044984	Gorilla gorilla	49.32	0.00e+00	863.00
IUUC-Hsa-046698	Homo sapiens	49.19	0.00e+00	863.00
IUUC-Hvu-047669	Hordeum vulgare	57.06	1.00e-128	450.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	49.19	0.00e+00	862.00
IUUC-Lch-050473	Latimeria chalumnae	49.44	0.00e+00	866.00
IUUC-Lpe-051579	Leersia perrieri	50.44	0.00e+00	834.00
IUUC-Loc-052675	Lepisosteus oculatus	49.69	0.00e+00	868.00
IUUC-Lma-053218	Leptosphaeria maculans	57.53	0.00e+00	935.00
IUUC-Laf-053757	Loxodonta africana	49.19	0.00e+00	858.00
IUUC-Mcc-054859	Macaca mulatta	49.32	0.00e+00	863.00
IUUC-Meu-056174	Macropus eugenii	39.40	1.00e-72	266.00
IUUC-Mor-057264	Magnaporthe oryzae	55.54	0.00e+00	888.00
IUUC-Mpo-057538	Magnaporthe poae	57.14	0.00e+00	921.00
IUUC-Mtr-058310	Medicago truncatula	51.02	0.00e+00	843.00
IUUC-Mla-058937	Melampsora laricipopulina	50.68	0.00e+00	859.00
IUUC-Mga-059875	Meleagris gallopavo	49.32	0.00e+00	861.00
IUUC-Mvi-060240	Microbotryum violaceum	49.19	0.00e+00	859.00
IUUC-Mmr-061261	Microcebus murinus	49.19	0.00e+00	863.00
IUUC-Mdo-062076	Monodelphis domestica	46.77	0.00e+00	869.00
IUUC-Mmu-063324	Mus musculus	47.35	0.00e+00	865.00
IUUC-Mac-064636	Musa acuminata	51.48	0.00e+00	830.00
IUUC-Mpu-065961	Mustela putorius furo	49.19	0.00e+00	863.00
IUUC-Mlu-067059	Myotis lucifugus	48.57	0.00e+00	841.00
IUUC-Nfi-068277	Neosartorya fischeri	56.67	0.00e+00	929.00
IUUC-Ncr-068659	Neurospora crassa	57.37	0.00e+00	959.00
IUUC-Nle-069034	Nomascus leucogenys	49.32	0.00e+00	863.00
IUUC-Opr-070334	Ochotona princeps	51.09	0.00e+00	823.00
IUUC-Ont-072111	Oreochromis niloticus	49.19	0.00e+00	866.00
IUUC-Oan-073416	Ornithorhynchus anatinus	48.84	0.00e+00	820.00
IUUC-Ocu-074522	Oryctolagus cuniculus	49.19	0.00e+00	861.00
IUUC-Oba-075760	Oryza barthii	50.64	0.00e+00	819.00
IUUC-Obr-076163	Oryza brachyantha	48.16	0.00e+00	844.00
IUUC-Ogl-077450	Oryza glaberrima	51.28	0.00e+00	842.00
IUUC-Ogu-078994	Oryza glumaepatula	50.64	0.00e+00	818.00
IUUC-Oin-079856	Oryza indica	47.87	0.00e+00	823.00
IUUC-Olo-080731	Oryza longistaminata	51.13	0.00e+00	802.00
IUUC-Ome-081554	Oryza meridionalis	44.98	0.00e+00	766.00
IUUC-Oni-082324	Oryza nivara	50.64	0.00e+00	817.00
IUUC-Opu-083400	Oryza punctata	48.43	0.00e+00	806.00
IUUC-Oru-084829	Oryza rufipogon	50.64	0.00e+00	818.00
IUUC-Osa-086026	Oryza sativa	51.41	0.00e+00	844.00
IUUC-Ola-087245	Oryzias latipes	49.19	0.00e+00	864.00
IUUC-Olu-087655	Ostreococcus lucimarinus	50.75	0.00e+00	841.00
IUUC-Oga-088163	Otolemur garnettii	47.64	0.00e+00	818.00
IUUC-Oar-089842	Ovis aries	49.32	0.00e+00	863.00
IUUC-Ptr-090501	Pan troglodytes	49.32	0.00e+00	863.00
IUUC-Pan-092011	Papio anubis	49.32	0.00e+00	863.00
IUUC-Psi-093308	Pelodiscus sinensis	49.32	0.00e+00	864.00
IUUC-Pma-094695	Petromyzon marinus	47.43	0.00e+00	788.00
IUUC-Pno-094785	Phaeosphaeria nodorum	64.38	2.00e-111	394.00
IUUC-Ppa-095412	Physcomitrella patens	51.68	0.00e+00	867.00
IUUC-Pfo-096587	Poecilia formosa	46.34	0.00e+00	868.00
IUUC-Pab-097926	Pongo abelii	48.01	0.00e+00	801.00
IUUC-Pop-099634	Populus trichocarpa	50.77	0.00e+00	836.00
IUUC-Pca-100965	Procavia capensis	48.44	0.00e+00	831.00
IUUC-Ppe-101470	Prunus persica	51.41	0.00e+00	837.00
IUUC-Pva-102451	Pteropus vampyrus	47.75	0.00e+00	695.00
IUUC-Pgr-103590	Puccinia graminis	51.08	0.00e+00	885.00
IUUC-Ptt-103868	Puccinia triticina	50.96	0.00e+00	885.00
IUUC-Pte-104274	Pyrenophora teres	58.45	0.00e+00	966.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	55.58	0.00e+00	911.00
IUUC-Rno-105979	Rattus norvegicus	42.51	0.00e+00	650.00
IUUC-Sce-106269	Saccharomyces cerevisiae	54.42	0.00e+00	966.00
IUUC-Sha-106905	Sarcophilus harrisii	49.19	0.00e+00	863.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	51.64	0.00e+00	843.00
IUUC-Spo-108299	Schizosaccharomyces pombe	50.69	0.00e+00	858.00
IUUC-Smo-108695	Selaginella moellendorffii	49.32	0.00e+00	813.00
IUUC-Sit-110239	Setaria italica	51.38	0.00e+00	851.00
IUUC-Sly-111775	Solanum lycopersicum	50.56	0.00e+00	839.00
IUUC-Stu-112906	Solanum tuberosum	49.60	0.00e+00	743.00
IUUC-Sar-113472	Sorex araneus	47.34	0.00e+00	634.00
IUUC-Sbi-114052	Sorghum bicolor	51.63	0.00e+00	855.00
IUUC-Sre-115040	Sporisorium reilianum	51.32	0.00e+00	876.00
IUUC-Ssc-115593	Sus scrofa	49.19	0.00e+00	862.00
IUUC-Tgu-117239	Taeniopygia guttata	49.19	0.00e+00	865.00
IUUC-Tru-118025	Takifugu rubripes	49.19	0.00e+00	860.00
IUUC-Tsy-118824	Tarsius syrichta	47.54	0.00e+00	642.00
IUUC-Tni-120142	Tetraodon nigroviridis	49.07	0.00e+00	858.00
IUUC-Tca-121613	Theobroma cacao	51.15	0.00e+00	844.00
IUUC-Tre-122072	Trichoderma reesei	56.52	0.00e+00	917.00
IUUC-Tvi-122546	Trichoderma virens	56.77	0.00e+00	924.00
IUUC-Tae-125395	Triticum aestivum	51.53	0.00e+00	847.00
IUUC-Tur-126283	Triticum urartu	45.72	0.00e+00	710.00
IUUC-Tme-127041	Tuber melanosporum	57.79	0.00e+00	970.00
IUUC-Tbe-127770	Tupaia belangeri	49.40	0.00e+00	725.00
IUUC-Ttr-129294	Tursiops truncatus	49.07	0.00e+00	860.00
IUUC-Uma-129351	Ustilago maydis	51.69	0.00e+00	877.00
IUUC-Vda-129716	Verticillium dahliae	55.97	0.00e+00	954.00
IUUC-Vpa-130037	Vicugna pacos	39.82	2.00e-96	344.00
IUUC-Vvi-131689	Vitis vinifera	51.79	0.00e+00	837.00
IUUC-Xtr-132633	Xenopus tropicalis	49.44	0.00e+00	863.00
IUUC-Xma-133347	Xiphophorus maculatus	45.38	0.00e+00	870.00
IUUC-Yli-134455	Yarrowia lipolytica	57.71	0.00e+00	951.00
IUUC-Zma-135867	Zea mays	50.56	0.00e+00	851.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence