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Tag Content
iUUCD ID IUUC-Loc-052675
Ensembl Protein ID ENSLOCP00000005222.1
UniProt Accession W5MA13; W5MA13_LEPOC
Genbank Protein ID ENSLOCP00000005222
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID AHAT01029705
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSLOCG00000004368.1 ENSLOCT00000005230.1 ENSLOCP00000005222.1
ENSLOCG00000004368.1 ENSLOCT00000005249.1 ENSLOCP00000005241.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.80e-34 114.8 183 224
UBD/Beta-Prp 1.00e-72 245.0 13 290
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++va
   Q: 190  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
            l+ ++nv +  
   Q: 279  SLRGSNNVALGY 290
           *99999987433 PP
   
Organism Lepisosteus oculatus
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RASKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Loc-052675|E3,WD_repeat;UBD,Beta-Prp|Lepisosteus oculatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGTGAAGCGA AGCAGGCAGC CATCTATTGG GAGGACTTAA AACCCAGTTC CTAGAAGGCA 60
AACATGATTT TCAACTAGAG TCTGGAACTC GCTGGAGGAC GGTGTGGTTG AAACTCATTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Loc-052675|E3,WD_repeat;UBD,Beta-Prp|Lepisosteus oculatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 52.87 0.00e+00 939.00
IUUC-Aml-002154 Ailuropoda melanoleuca 94.37 0.00e+00 1696.00
IUUC-Atr-003090 Amborella trichopoda 59.05 0.00e+00 1075.00
IUUC-Apl-003976 Anas platyrhynchos 92.99 0.00e+00 1717.00
IUUC-Aca-004301 Anolis carolinensis 92.73 0.00e+00 1702.00
IUUC-Aly-006508 Arabidopsis lyrata 61.47 0.00e+00 1097.00
IUUC-Ath-007630 Arabidopsis thaliana 61.74 0.00e+00 1108.00
IUUC-Ago-007914 Ashbya gossypii 46.44 0.00e+00 759.00
IUUC-Acl-008237 Aspergillus clavatus 56.12 0.00e+00 965.00
IUUC-Afl-008535 Aspergillus flavus 55.61 0.00e+00 910.00
IUUC-Afu-008845 Aspergillus fumigatus 55.32 0.00e+00 936.00
IUUC-Ani-009135 Aspergillus nidulans 55.44 0.00e+00 913.00
IUUC-Ang-009654 Aspergillus niger 55.46 0.00e+00 857.00
IUUC-Aor-009939 Aspergillus oryzae 53.11 0.00e+00 968.00
IUUC-Ate-010355 Aspergillus terreus 53.90 0.00e+00 914.00
IUUC-Ame-010922 Astyanax mexicanus 87.72 0.00e+00 1536.00
IUUC-Bgr-012249 Blumeria graminis 53.64 0.00e+00 923.00
IUUC-Bta-013579 Bos taurus 95.93 0.00e+00 1455.00
IUUC-Bci-013866 Botrytis cinerea 55.30 0.00e+00 926.00
IUUC-Bdi-015046 Brachypodium distachyon 61.86 0.00e+00 1105.00
IUUC-Bol-016271 Brassica oleracea 61.71 0.00e+00 1113.00
IUUC-Bra-017758 Brassica rapa 59.65 0.00e+00 1112.00
IUUC-Cel-018387 Caenorhabditis elegans 63.96 0.00e+00 1189.00
IUUC-Cja-019145 Callithrix jacchus 94.26 0.00e+00 1698.00
IUUC-Cfa-020564 Canis familiaris 94.49 0.00e+00 1701.00
IUUC-Cpo-022201 Cavia porcellus 93.20 0.00e+00 1699.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 59.56 0.00e+00 995.00
IUUC-Csa-023383 Chlorocebus sabaeus 95.41 0.00e+00 1160.00
IUUC-Cho-024454 Choloepus hoffmanni 89.66 0.00e+00 1382.00
IUUC-Cin-025681 Ciona intestinalis 76.59 0.00e+00 1374.00
IUUC-Csv-026012 Ciona savignyi 77.66 0.00e+00 1350.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 51.85 0.00e+00 845.00
IUUC-Cne-026986 Cryptococcus neoformans 51.21 0.00e+00 915.00
IUUC-Cme-027219 Cyanidioschyzon merolae 45.94 0.00e+00 858.00
IUUC-Dre-027846 Danio rerio 91.38 0.00e+00 1722.00
IUUC-Dor-030462 Dipodomys ordii 90.23 0.00e+00 1251.00
IUUC-Dse-031268 Dothistroma septosporum 55.19 0.00e+00 951.00
IUUC-Dme-031791 Drosophila melanogaster 72.27 0.00e+00 1273.00
IUUC-Ete-033166 Echinops telfairi 85.84 0.00e+00 997.00
IUUC-Eca-034180 Equus caballus 92.50 0.00e+00 1649.00
IUUC-Eeu-035086 Erinaceus europaeus 80.78 0.00e+00 813.00
IUUC-Fca-036265 Felis catus 89.45 0.00e+00 1697.00
IUUC-Fal-037202 Ficedula albicollis 92.30 0.00e+00 1655.00
IUUC-Fox-037711 Fusarium oxysporum 55.97 0.00e+00 882.00
IUUC-Fso-038268 Fusarium solani 55.93 0.00e+00 884.00
IUUC-Gmo-039046 Gadus morhua 94.91 0.00e+00 1692.00
IUUC-Ggr-039863 Gaeumannomyces graminis 54.96 0.00e+00 902.00
IUUC-Gga-041112 Gallus gallus 93.79 0.00e+00 1716.00
IUUC-Gac-041733 Gasterosteus aculeatus 94.94 0.00e+00 1663.00
IUUC-Gma-042910 Glycine max 61.55 0.00e+00 1124.00
IUUC-Ggo-044984 Gorilla gorilla 94.14 0.00e+00 1693.00
IUUC-Hsa-046698 Homo sapiens 94.02 0.00e+00 1693.00
IUUC-Hvu-047669 Hordeum vulgare 70.62 1.00e-168 585.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 92.87 0.00e+00 1696.00
IUUC-Kpa-049265 Komagataella pastoris 49.69 0.00e+00 867.00
IUUC-Lch-050473 Latimeria chalumnae 93.32 0.00e+00 1732.00
IUUC-Lpe-051579 Leersia perrieri 60.62 0.00e+00 1094.00
IUUC-Lma-053218 Leptosphaeria maculans 54.17 0.00e+00 921.00
IUUC-Laf-053757 Loxodonta africana 88.92 0.00e+00 1689.00
IUUC-Mcc-054859 Macaca mulatta 94.26 0.00e+00 1697.00
IUUC-Meu-056174 Macropus eugenii 92.89 0.00e+00 725.00
IUUC-Mor-057264 Magnaporthe oryzae 55.45 0.00e+00 886.00
IUUC-Mpo-057538 Magnaporthe poae 55.09 0.00e+00 915.00
IUUC-Mtr-058310 Medicago truncatula 61.66 0.00e+00 1130.00
IUUC-Mla-058937 Melampsora laricipopulina 53.84 0.00e+00 912.00
IUUC-Mga-059875 Meleagris gallopavo 93.46 0.00e+00 1707.00
IUUC-Mvi-060240 Microbotryum violaceum 49.76 0.00e+00 913.00
IUUC-Mmr-061261 Microcebus murinus 93.10 0.00e+00 1702.00
IUUC-Mdo-062076 Monodelphis domestica 92.22 0.00e+00 1716.00
IUUC-Mmu-063324 Mus musculus 89.45 0.00e+00 1695.00
IUUC-Mac-064636 Musa acuminata 60.00 0.00e+00 1085.00
IUUC-Mpu-065961 Mustela putorius furo 94.37 0.00e+00 1696.00
IUUC-Mlu-067059 Myotis lucifugus 92.20 0.00e+00 1648.00
IUUC-Nfi-068277 Neosartorya fischeri 52.33 0.00e+00 925.00
IUUC-Ncr-068659 Neurospora crassa 53.07 0.00e+00 914.00
IUUC-Nle-069034 Nomascus leucogenys 92.98 0.00e+00 1698.00
IUUC-Opr-070334 Ochotona princeps 95.65 0.00e+00 1493.00
IUUC-Ont-071563 Oreochromis niloticus 95.40 0.00e+00 1710.00
IUUC-Oan-073416 Ornithorhynchus anatinus 94.65 0.00e+00 1623.00
IUUC-Ocu-074522 Oryctolagus cuniculus 89.35 0.00e+00 1693.00
IUUC-Oba-075760 Oryza barthii 60.34 0.00e+00 1080.00
IUUC-Obr-076201 Oryza brachyantha 60.63 0.00e+00 1105.00
IUUC-Ogl-077450 Oryza glaberrima 61.55 0.00e+00 1106.00
IUUC-Ogu-078994 Oryza glumaepatula 60.34 0.00e+00 1077.00
IUUC-Oin-079856 Oryza indica 59.32 0.00e+00 1077.00
IUUC-Olo-080731 Oryza longistaminata 59.76 0.00e+00 1065.00
IUUC-Ome-081762 Oryza meridionalis 56.60 0.00e+00 1000.00
IUUC-Oni-082324 Oryza nivara 60.34 0.00e+00 1078.00
IUUC-Opu-083400 Oryza punctata 56.48 0.00e+00 1066.00
IUUC-Oru-084829 Oryza rufipogon 60.34 0.00e+00 1078.00
IUUC-Osa-086026 Oryza sativa 61.55 0.00e+00 1110.00
IUUC-Ola-087245 Oryzias latipes 93.53 0.00e+00 1710.00
IUUC-Olu-087655 Ostreococcus lucimarinus 59.98 0.00e+00 1058.00
IUUC-Oga-088163 Otolemur garnettii 86.56 0.00e+00 1625.00
IUUC-Oar-089842 Ovis aries 94.02 0.00e+00 1696.00
IUUC-Ptr-090501 Pan troglodytes 94.26 0.00e+00 1696.00
IUUC-Pan-092011 Papio anubis 94.26 0.00e+00 1698.00
IUUC-Psi-093308 Pelodiscus sinensis 93.00 0.00e+00 1713.00
IUUC-Pma-094695 Petromyzon marinus 80.42 0.00e+00 1437.00
IUUC-Pno-094785 Phaeosphaeria nodorum 62.07 1.00e-111 397.00
IUUC-Ppa-095911 Physcomitrella patens 61.96 0.00e+00 1129.00
IUUC-Pfo-096587 Poecilia formosa 92.41 0.00e+00 1716.00
IUUC-Pab-097926 Pongo abelii 87.15 0.00e+00 1605.00
IUUC-Pop-099634 Populus trichocarpa 61.19 0.00e+00 1103.00
IUUC-Pca-100965 Procavia capensis 92.61 0.00e+00 1654.00
IUUC-Ppe-101470 Prunus persica 62.39 0.00e+00 1116.00
IUUC-Pva-102451 Pteropus vampyrus 89.47 0.00e+00 1244.00
IUUC-Pgr-103453 Puccinia graminis 53.62 0.00e+00 924.00
IUUC-Ptt-103868 Puccinia triticina 54.05 0.00e+00 922.00
IUUC-Pte-104274 Pyrenophora teres 54.96 0.00e+00 952.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 54.28 0.00e+00 901.00
IUUC-Rno-105979 Rattus norvegicus 81.82 0.00e+00 1238.00
IUUC-Sce-106269 Saccharomyces cerevisiae 48.06 0.00e+00 790.00
IUUC-Sha-106905 Sarcophilus harrisii 93.12 0.00e+00 1707.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.59 0.00e+00 832.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.90 0.00e+00 830.00
IUUC-Smo-108695 Selaginella moellendorffii 62.22 0.00e+00 1083.00
IUUC-Sit-110239 Setaria italica 61.55 0.00e+00 1107.00
IUUC-Sly-111525 Solanum lycopersicum 62.27 0.00e+00 1120.00
IUUC-Stu-112906 Solanum tuberosum 60.72 0.00e+00 996.00
IUUC-Sar-113472 Sorex araneus 88.51 0.00e+00 1137.00
IUUC-Sbi-114052 Sorghum bicolor 63.70 0.00e+00 1117.00
IUUC-Sre-115040 Sporisorium reilianum 52.13 0.00e+00 914.00
IUUC-Ssc-115593 Sus scrofa 89.57 0.00e+00 1701.00
IUUC-Tgu-117239 Taeniopygia guttata 92.54 0.00e+00 1712.00
IUUC-Tru-118025 Takifugu rubripes 93.30 0.00e+00 1703.00
IUUC-Tsy-118824 Tarsius syrichta 88.06 0.00e+00 1148.00
IUUC-Tni-120142 Tetraodon nigroviridis 94.12 0.00e+00 1697.00
IUUC-Tca-121613 Theobroma cacao 59.95 0.00e+00 1113.00
IUUC-Tre-122072 Trichoderma reesei 55.09 0.00e+00 930.00
IUUC-Tvi-122546 Trichoderma virens 54.59 0.00e+00 915.00
IUUC-Tae-125292 Triticum aestivum 61.19 0.00e+00 1099.00
IUUC-Tur-126283 Triticum urartu 53.71 0.00e+00 939.00
IUUC-Tme-127041 Tuber melanosporum 56.29 0.00e+00 976.00
IUUC-Tbe-127770 Tupaia belangeri 90.36 0.00e+00 1255.00
IUUC-Ttr-129294 Tursiops truncatus 94.37 0.00e+00 1698.00
IUUC-Uma-129351 Ustilago maydis 50.91 0.00e+00 905.00
IUUC-Vda-129716 Verticillium dahliae 54.93 0.00e+00 952.00
IUUC-Vpa-130037 Vicugna pacos 84.55 0.00e+00 838.00
IUUC-Vvi-131689 Vitis vinifera 61.42 0.00e+00 1110.00
IUUC-Xtr-132633 Xenopus tropicalis 90.95 0.00e+00 1680.00
IUUC-Xma-133347 Xiphophorus maculatus 92.64 0.00e+00 1719.00
IUUC-Yli-134455 Yarrowia lipolytica 50.51 0.00e+00 840.00
IUUC-Zma-135867 Zea mays 61.88 0.00e+00 1117.00
Created Date 25-Jun-2017

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