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Tag Content
UUCD2 ID IUUC-Oga-088163
UUCD1 version UUC-OtG-00420
Ensembl Protein ID ENSOGAP00000009183.2
UniProt Accession H0X2B0; H0X2B0_OTOGA
Genbank Protein ID ENSOGAP00000009183
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID AAQR03062500
Gene Name COPB2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000010265.2 ENSOGAT00000010270.2 ENSOGAP00000009183.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.80e-33 112.5 182 223
UBD/Beta-Prp 1.00e-71 241.6 12 291
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 182  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 223
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d+
   Q: 12   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDY 100
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 101  IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 188
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++  f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++va
   Q: 189  CIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVA 277
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlgse 285
            l+ ++nv +  +e
   Q: 278  SLRGSNNVALGYDE 291
           *9999998765554 PP
   
Organism Otolemur garnettii
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
PLRLDIKRKL TARSDRVKSV DLHPTEPWML ASLYNGSVCV WNHETQTLVK TFEVCDLPVR 60
AAKFVARKNW VVTGADDMQI RVFNYNTLER VHMFEAHSDY IRCIAVHPTQ PFILTSSDDM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088163|E3,WD_repeat;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCTCTGCGAC TTGATATTAA AAGAAAACTA ACTGCTAGAT CAGATCGAGT TAAGAGTGTG 60
GATTTGCATC CTACGGAGCC ATGGATGTTG GCAAGTCTTT ACAATGGCAG TGTGTGTGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088163|E3,WD_repeat;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 51.26 0.00e+00 889.00
IUUC-Aml-002154 Ailuropoda melanoleuca 95.59 0.00e+00 1755.00
IUUC-Atr-003090 Amborella trichopoda 56.73 0.00e+00 1018.00
IUUC-Apl-003976 Anas platyrhynchos 91.31 0.00e+00 1659.00
IUUC-Aca-004301 Anolis carolinensis 91.47 0.00e+00 1646.00
IUUC-Aly-006508 Arabidopsis lyrata 58.11 0.00e+00 1039.00
IUUC-Ath-007635 Arabidopsis thaliana 58.22 0.00e+00 1039.00
IUUC-Ago-007914 Ashbya gossypii 45.06 0.00e+00 722.00
IUUC-Acl-008237 Aspergillus clavatus 54.20 0.00e+00 922.00
IUUC-Afl-008535 Aspergillus flavus 53.94 0.00e+00 870.00
IUUC-Afu-008845 Aspergillus fumigatus 52.61 0.00e+00 899.00
IUUC-Ani-009135 Aspergillus nidulans 54.15 0.00e+00 874.00
IUUC-Ang-009654 Aspergillus niger 53.87 0.00e+00 817.00
IUUC-Aor-009939 Aspergillus oryzae 52.93 0.00e+00 927.00
IUUC-Ate-010355 Aspergillus terreus 52.25 0.00e+00 875.00
IUUC-Ame-010922 Astyanax mexicanus 80.92 0.00e+00 1421.00
IUUC-Bgr-012249 Blumeria graminis 52.16 0.00e+00 891.00
IUUC-Bta-013579 Bos taurus 94.97 0.00e+00 1409.00
IUUC-Bci-013866 Botrytis cinerea 54.18 0.00e+00 885.00
IUUC-Bdi-015046 Brachypodium distachyon 58.77 0.00e+00 1052.00
IUUC-Bol-015731 Brassica oleracea 59.13 0.00e+00 1057.00
IUUC-Bra-017758 Brassica rapa 58.46 0.00e+00 1058.00
IUUC-Cel-018387 Caenorhabditis elegans 62.80 0.00e+00 1120.00
IUUC-Cja-019145 Callithrix jacchus 95.92 0.00e+00 1757.00
IUUC-Cfa-020564 Canis familiaris 95.81 0.00e+00 1749.00
IUUC-Cpo-022201 Cavia porcellus 93.94 0.00e+00 1729.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 56.54 0.00e+00 934.00
IUUC-Csa-023383 Chlorocebus sabaeus 93.49 0.00e+00 1107.00
IUUC-Cho-024454 Choloepus hoffmanni 88.60 0.00e+00 1337.00
IUUC-Cin-025681 Ciona intestinalis 73.32 0.00e+00 1309.00
IUUC-Csv-026012 Ciona savignyi 74.70 0.00e+00 1283.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 50.12 0.00e+00 800.00
IUUC-Cne-026986 Cryptococcus neoformans 50.12 0.00e+00 867.00
IUUC-Cme-027219 Cyanidioschyzon merolae 46.53 0.00e+00 806.00
IUUC-Dre-027846 Danio rerio 90.19 0.00e+00 1602.00
IUUC-Dor-030462 Dipodomys ordii 88.59 0.00e+00 1197.00
IUUC-Dse-031268 Dothistroma septosporum 53.20 0.00e+00 914.00
IUUC-Dme-031791 Drosophila melanogaster 67.05 0.00e+00 1214.00
IUUC-Ete-033166 Echinops telfairi 83.72 0.00e+00 945.00
IUUC-Eca-034180 Equus caballus 92.94 0.00e+00 1677.00
IUUC-Eeu-035086 Erinaceus europaeus 88.35 0.00e+00 895.00
IUUC-Fca-036265 Felis catus 95.48 0.00e+00 1739.00
IUUC-Fal-037202 Ficedula albicollis 90.91 0.00e+00 1598.00
IUUC-Fox-037711 Fusarium oxysporum 54.97 0.00e+00 846.00
IUUC-Fso-038268 Fusarium solani 54.45 0.00e+00 844.00
IUUC-Gmo-039046 Gadus morhua 89.47 0.00e+00 1582.00
IUUC-Ggr-039863 Gaeumannomyces graminis 53.56 0.00e+00 862.00
IUUC-Gga-041112 Gallus gallus 91.43 0.00e+00 1660.00
IUUC-Gac-041733 Gasterosteus aculeatus 89.48 0.00e+00 1543.00
IUUC-Gma-042910 Glycine max 60.17 0.00e+00 1060.00
IUUC-Ggo-044984 Gorilla gorilla 95.37 0.00e+00 1751.00
IUUC-Hsa-046698 Homo sapiens 95.48 0.00e+00 1750.00
IUUC-Hvu-047669 Hordeum vulgare 71.21 1.00e-159 555.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 93.61 0.00e+00 1709.00
IUUC-Kpa-049265 Komagataella pastoris 47.64 0.00e+00 819.00
IUUC-Lch-050473 Latimeria chalumnae 87.93 0.00e+00 1643.00
IUUC-Lpe-051579 Leersia perrieri 59.00 0.00e+00 1043.00
IUUC-Loc-052675 Lepisosteus oculatus 90.28 0.00e+00 1628.00
IUUC-Lma-053218 Leptosphaeria maculans 52.57 0.00e+00 882.00
IUUC-Laf-053757 Loxodonta africana 95.38 0.00e+00 1747.00
IUUC-Mcc-054859 Macaca mulatta 95.92 0.00e+00 1756.00
IUUC-Meu-056174 Macropus eugenii 95.82 0.00e+00 753.00
IUUC-Mor-057264 Magnaporthe oryzae 54.09 0.00e+00 850.00
IUUC-Mpo-057538 Magnaporthe poae 53.44 0.00e+00 872.00
IUUC-Mtr-058310 Medicago truncatula 60.29 0.00e+00 1068.00
IUUC-Mla-058937 Melampsora laricipopulina 52.08 0.00e+00 870.00
IUUC-Mga-059875 Meleagris gallopavo 91.22 0.00e+00 1656.00
IUUC-Mvi-060240 Microbotryum violaceum 48.27 0.00e+00 880.00
IUUC-Mmr-061261 Microcebus murinus 96.14 0.00e+00 1764.00
IUUC-Mdo-062076 Monodelphis domestica 92.54 0.00e+00 1684.00
IUUC-Mmu-063324 Mus musculus 95.04 0.00e+00 1742.00
IUUC-Mac-064636 Musa acuminata 57.73 0.00e+00 1026.00
IUUC-Mpu-065961 Mustela putorius furo 95.92 0.00e+00 1751.00
IUUC-Mlu-067059 Myotis lucifugus 94.72 0.00e+00 1667.00
IUUC-Nfi-068277 Neosartorya fischeri 52.31 0.00e+00 890.00
IUUC-Ncr-068659 Neurospora crassa 51.10 0.00e+00 871.00
IUUC-Nle-069034 Nomascus leucogenys 95.92 0.00e+00 1757.00
IUUC-Opr-070334 Ochotona princeps 94.71 0.00e+00 1451.00
IUUC-Ont-071563 Oreochromis niloticus 85.31 0.00e+00 1604.00
IUUC-Oan-073416 Ornithorhynchus anatinus 94.42 0.00e+00 1589.00
IUUC-Ocu-074522 Oryctolagus cuniculus 95.48 0.00e+00 1749.00
IUUC-Oba-075760 Oryza barthii 56.34 0.00e+00 1025.00
IUUC-Obr-076163 Oryza brachyantha 59.95 0.00e+00 1044.00
IUUC-Ogl-077450 Oryza glaberrima 57.51 0.00e+00 1053.00
IUUC-Ogu-078994 Oryza glumaepatula 56.34 0.00e+00 1023.00
IUUC-Oin-079856 Oryza indica 55.68 0.00e+00 1026.00
IUUC-Olo-080731 Oryza longistaminata 55.68 0.00e+00 1008.00
IUUC-Ome-081762 Oryza meridionalis 52.73 0.00e+00 944.00
IUUC-Oni-082324 Oryza nivara 56.34 0.00e+00 1023.00
IUUC-Opu-083400 Oryza punctata 54.24 0.00e+00 1013.00
IUUC-Oru-084829 Oryza rufipogon 56.34 0.00e+00 1023.00
IUUC-Osa-086026 Oryza sativa 57.51 0.00e+00 1055.00
IUUC-Ola-087245 Oryzias latipes 85.21 0.00e+00 1609.00
IUUC-Olu-087655 Ostreococcus lucimarinus 57.35 0.00e+00 1001.00
IUUC-Oar-089842 Ovis aries 95.21 0.00e+00 1729.00
IUUC-Ptr-090501 Pan troglodytes 95.59 0.00e+00 1750.00
IUUC-Pan-092011 Papio anubis 95.81 0.00e+00 1753.00
IUUC-Psi-093308 Pelodiscus sinensis 93.99 0.00e+00 1659.00
IUUC-Pma-094695 Petromyzon marinus 73.17 0.00e+00 1369.00
IUUC-Pno-094785 Phaeosphaeria nodorum 56.16 2.00e-98 353.00
IUUC-Ppa-095911 Physcomitrella patens 59.36 0.00e+00 1069.00
IUUC-Pfo-096587 Poecilia formosa 83.23 0.00e+00 1602.00
IUUC-Pab-097926 Pongo abelii 93.09 0.00e+00 1656.00
IUUC-Pop-099634 Populus trichocarpa 59.69 0.00e+00 1049.00
IUUC-Pca-100965 Procavia capensis 93.83 0.00e+00 1699.00
IUUC-Ppe-101470 Prunus persica 60.41 0.00e+00 1063.00
IUUC-Pva-102451 Pteropus vampyrus 87.99 0.00e+00 1194.00
IUUC-Pgr-103453 Puccinia graminis 52.63 0.00e+00 882.00
IUUC-Ptt-103868 Puccinia triticina 53.17 0.00e+00 881.00
IUUC-Pte-104274 Pyrenophora teres 53.36 0.00e+00 914.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 52.61 0.00e+00 861.00
IUUC-Rno-105979 Rattus norvegicus 80.51 0.00e+00 1189.00
IUUC-Sce-106269 Saccharomyces cerevisiae 45.90 0.00e+00 756.00
IUUC-Sha-106905 Sarcophilus harrisii 93.89 0.00e+00 1683.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 46.09 0.00e+00 800.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.66 0.00e+00 800.00
IUUC-Smo-108695 Selaginella moellendorffii 59.61 0.00e+00 1018.00
IUUC-Sit-110692 Setaria italica 60.53 0.00e+00 1045.00
IUUC-Sly-111775 Solanum lycopersicum 59.88 0.00e+00 1036.00
IUUC-Stu-112906 Solanum tuberosum 59.36 0.00e+00 933.00
IUUC-Sar-113472 Sorex araneus 86.61 0.00e+00 1086.00
IUUC-Sbi-114052 Sorghum bicolor 60.62 0.00e+00 1056.00
IUUC-Sre-115040 Sporisorium reilianum 50.85 0.00e+00 867.00
IUUC-Ssc-115593 Sus scrofa 95.48 0.00e+00 1751.00
IUUC-Tgu-117239 Taeniopygia guttata 91.20 0.00e+00 1660.00
IUUC-Tru-118025 Takifugu rubripes 89.42 0.00e+00 1593.00
IUUC-Tsy-118824 Tarsius syrichta 86.17 0.00e+00 1096.00
IUUC-Tni-120142 Tetraodon nigroviridis 87.37 0.00e+00 1587.00
IUUC-Tca-121613 Theobroma cacao 59.81 0.00e+00 1057.00
IUUC-Tre-122072 Trichoderma reesei 53.14 0.00e+00 890.00
IUUC-Tvi-122546 Trichoderma virens 52.77 0.00e+00 878.00
IUUC-Tae-125292 Triticum aestivum 59.37 0.00e+00 1048.00
IUUC-Tur-126283 Triticum urartu 52.09 0.00e+00 890.00
IUUC-Tme-127041 Tuber melanosporum 54.66 0.00e+00 930.00
IUUC-Tbe-127770 Tupaia belangeri 87.69 0.00e+00 1197.00
IUUC-Ttr-129294 Tursiops truncatus 95.59 0.00e+00 1751.00
IUUC-Uma-129351 Ustilago maydis 49.27 0.00e+00 854.00
IUUC-Vda-129716 Verticillium dahliae 53.75 0.00e+00 911.00
IUUC-Vpa-130037 Vicugna pacos 90.26 0.00e+00 947.00
IUUC-Vvi-131689 Vitis vinifera 59.17 0.00e+00 1058.00
IUUC-Xtr-132633 Xenopus tropicalis 91.04 0.00e+00 1613.00
IUUC-Xma-133347 Xiphophorus maculatus 84.95 0.00e+00 1610.00
IUUC-Yli-134455 Yarrowia lipolytica 48.73 0.00e+00 803.00
IUUC-Zma-135706 Zea mays 59.53 0.00e+00 1064.00
Created Date 25-Jun-2017

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