iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089885

Ensembl Protein ID

ENSOARP00000017656.1

UniProt Accession

W5Q4L6; W5Q4L6_SHEEP

Genbank Protein ID

ENSOARP00000017656

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01061684

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016445.1	ENSOART00000017906.1	ENSOARP00000017656.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.90e-08	34.4	4	42
ULD/UDP/UFD/UBX	3.30e-20	72.6	210	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF++ +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPKGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    + l+  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 210  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEDLGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 291
           578*****************************************************************************98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAELTALESL IEMGFPKGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLATPLGHVL 60
GREPTPSEQG GPKGPGSAVG EGKPVLTEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCCGCGG AAGCGACGGT GGCGGCGTCA TGGCGGAGCT GACGGCTCTG GAGAGTCTCA 60
TCGAGATGGG CTTCCCCAAG GGACGCGCGT AAGGGAGCCC CCTAACCCAG GGCCGCGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

KEGG

oas:101113110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	38.75	9.00e-10	58.20
IUUC-Aml-002325	Ailuropoda melanoleuca	92.49	1.00e-109	389.00
IUUC-Atr-002907	Amborella trichopoda	43.75	1.00e-09	57.40
IUUC-Aca-004329	Anolis carolinensis	71.08	1.00e-47	182.00
IUUC-Aly-005639	Arabidopsis lyrata	45.88	2.00e-12	67.00
IUUC-Ath-006887	Arabidopsis thaliana	45.88	2.00e-12	67.00
IUUC-Ago-007989	Ashbya gossypii	37.18	7.00e-07	47.80
IUUC-Ame-011399	Astyanax mexicanus	53.42	8.00e-61	226.00
IUUC-Bta-013151	Bos taurus	98.32	2.00e-133	468.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	1.00e-09	57.80
IUUC-Bol-016537	Brassica oleracea	45.88	9.00e-12	64.70
IUUC-Bra-017906	Brassica rapa	61.36	1.00e-11	64.70
IUUC-Cel-018300	Caenorhabditis elegans	34.85	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	92.96	9.00e-101	359.00
IUUC-Cfa-020997	Canis familiaris	89.79	7.00e-89	320.00
IUUC-Cpo-021736	Cavia porcellus	78.04	6.00e-83	300.00
IUUC-Csa-024040	Chlorocebus sabaeus	93.27	7.00e-100	356.00
IUUC-Cho-024543	Choloepus hoffmanni	93.56	9.00e-71	259.00
IUUC-Cin-025719	Ciona intestinalis	39.53	4.00e-37	147.00
IUUC-Csv-025854	Ciona savignyi	38.33	3.00e-35	142.00
IUUC-Cne-027046	Cryptococcus neoformans	39.51	5.00e-09	55.10
IUUC-Cme-027235	Cyanidioschyzon merolae	45.45	9.00e-08	51.60
IUUC-Dre-027745	Danio rerio	51.16	4.00e-58	218.00
IUUC-Dno-029598	Dasypus novemcinctus	89.90	6.00e-100	356.00
IUUC-Dor-030917	Dipodomys ordii	79.58	4.00e-87	314.00
IUUC-Dme-032055	Drosophila melanogaster	41.82	4.00e-22	98.60
IUUC-Ete-032960	Echinops telfairi	75.18	4.00e-76	278.00
IUUC-Eca-034294	Equus caballus	94.59	8.00e-113	399.00
IUUC-Eeu-034906	Erinaceus europaeus	88.42	2.00e-104	372.00
IUUC-Fca-035653	Felis catus	90.49	5.00e-93	333.00
IUUC-Gmo-038755	Gadus morhua	50.64	3.00e-54	205.00
IUUC-Gac-042481	Gasterosteus aculeatus	53.23	2.00e-55	208.00
IUUC-Gma-042684	Glycine max	52.27	2.00e-10	60.10
IUUC-Ggo-044821	Gorilla gorilla	92.61	1.00e-93	336.00
IUUC-Hsa-046797	Homo sapiens	93.58	3.00e-103	368.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	94.26	4.00e-113	400.00
IUUC-Lch-049508	Latimeria chalumnae	53.07	2.00e-57	216.00
IUUC-Laf-053932	Loxodonta africana	94.59	7.00e-131	459.00
IUUC-Mcc-055300	Macaca mulatta	93.60	5.00e-100	357.00
IUUC-Mtr-058774	Medicago truncatula	50.00	8.00e-10	57.40
IUUC-Mla-059083	Melampsora laricipopulina	29.11	1.00e-06	47.40
IUUC-Mvi-060245	Microbotryum violaceum	39.76	4.00e-11	62.00
IUUC-Mmr-060979	Microcebus murinus	91.22	2.00e-105	375.00
IUUC-Mdo-062299	Monodelphis domestica	85.82	1.00e-97	349.00
IUUC-Mmu-063212	Mus musculus	91.25	7.00e-116	409.00
IUUC-Mac-065072	Musa acuminata	58.54	1.00e-10	60.50
IUUC-Mpu-066540	Mustela putorius furo	92.57	1.00e-111	395.00
IUUC-Mlu-067589	Myotis lucifugus	91.92	8.00e-106	376.00
IUUC-Nle-069045	Nomascus leucogenys	92.09	7.00e-76	276.00
IUUC-Opr-070772	Ochotona princeps	85.62	2.00e-91	328.00
IUUC-Ont-072006	Oreochromis niloticus	53.18	2.00e-56	212.00
IUUC-Oan-073244	Ornithorhynchus anatinus	60.36	2.00e-42	165.00
IUUC-Ocu-074333	Oryctolagus cuniculus	92.57	2.00e-102	365.00
IUUC-Oba-075451	Oryza barthii	49.06	5.00e-11	62.40
IUUC-Obr-076923	Oryza brachyantha	55.10	1.00e-11	64.30
IUUC-Ogl-077259	Oryza glaberrima	38.36	9.00e-10	58.20
IUUC-Ogu-078589	Oryza glumaepatula	49.06	5.00e-11	62.40
IUUC-Oin-079151	Oryza indica	49.06	5.00e-11	62.40
IUUC-Olo-080934	Oryza longistaminata	45.90	1.00e-10	60.50
IUUC-Ome-081253	Oryza meridionalis	49.06	4.00e-11	62.40
IUUC-Oni-082110	Oryza nivara	38.36	3.00e-10	59.30
IUUC-Opu-083336	Oryza punctata	49.06	5.00e-11	62.00
IUUC-Oru-085235	Oryza rufipogon	49.06	5.00e-11	62.40
IUUC-Osa-085611	Oryza sativa	49.06	5.00e-11	62.40
IUUC-Ola-086781	Oryzias latipes	53.07	5.00e-54	204.00
IUUC-Oga-088429	Otolemur garnettii	92.93	3.00e-101	361.00
IUUC-Ptr-091315	Pan troglodytes	92.96	1.00e-95	342.00
IUUC-Pan-092885	Papio anubis	93.27	7.00e-100	356.00
IUUC-Psi-093299	Pelodiscus sinensis	69.96	1.00e-62	233.00
IUUC-Pma-094221	Petromyzon marinus	63.22	9.00e-28	115.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.42	3.00e-54	205.00
IUUC-Pab-097881	Pongo abelii	86.20	3.00e-98	351.00
IUUC-Pop-098863	Populus trichocarpa	52.94	9.00e-12	64.70
IUUC-Pca-100977	Procavia capensis	91.64	9.00e-107	379.00
IUUC-Ppe-101243	Prunus persica	47.06	5.00e-10	58.50
IUUC-Pva-102169	Pteropus vampyrus	93.31	3.00e-98	351.00
IUUC-Rno-105459	Rattus norvegicus	90.91	1.00e-115	408.00
IUUC-Sha-107526	Sarcophilus harrisii	87.46	4.00e-98	350.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	29.29	9.00e-08	51.60
IUUC-Sit-110434	Setaria italica	35.23	2.00e-09	56.20
IUUC-Sly-111766	Solanum lycopersicum	47.54	4.00e-11	62.40
IUUC-Stu-112122	Solanum tuberosum	47.54	5.00e-11	62.40
IUUC-Sar-112945	Sorex araneus	90.91	4.00e-69	254.00
IUUC-Sbi-114159	Sorghum bicolor	32.43	1.00e-10	60.80
IUUC-Ssc-116114	Sus scrofa	94.26	4.00e-101	360.00
IUUC-Tru-117839	Takifugu rubripes	53.67	3.00e-55	208.00
IUUC-Tsy-118813	Tarsius syrichta	91.06	2.00e-60	225.00
IUUC-Tni-120504	Tetraodon nigroviridis	55.52	1.00e-55	209.00
IUUC-Tae-124974	Triticum aestivum	38.75	1.00e-09	57.40
IUUC-Tur-126615	Triticum urartu	38.75	1.00e-09	57.40
IUUC-Tbe-128034	Tupaia belangeri	92.25	7.00e-104	370.00
IUUC-Ttr-128468	Tursiops truncatus	89.19	6.00e-107	380.00
IUUC-Uma-129569	Ustilago maydis	34.62	2.00e-05	43.10
IUUC-Vpa-130179	Vicugna pacos	87.88	3.00e-78	284.00
IUUC-Vvi-131064	Vitis vinifera	49.02	3.00e-10	59.70
IUUC-Xtr-132119	Xenopus tropicalis	61.74	1.00e-66	246.00
IUUC-Xma-134067	Xiphophorus maculatus	52.58	4.00e-55	208.00
IUUC-Zma-134709	Zea mays	32.61	1.00e-09	57.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence