iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052314

Ensembl Protein ID

ENSLOCP00000013524.1

UniProt Accession

W5MYR5; W5MYR5_LEPOC

Genbank Protein ID

ENSLOCP00000013524

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01017629

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000011016.1	ENSLOCT00000013553.1	ENSLOCP00000013524.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-15	57.1	96	151

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L++kkGd  ++i  ++++++W+++ +  +gk+G +P+n+v+ ++
   Q: 96   FVALYDYEARTSDDLSFKKGDRFQII--NNTEGDWWEARSINTGKKGYIPSNYVAPAD 151
           679***********************..8999**********************9875 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGCIKSKEDK GPTMKYRPEN TTESVSAHVG HYGPDPTQLN QSPALKGPAS NYNSHSMTPF 60
GGSSLMTPFG GASSSSFSSA VTNPFPGSAT GGVTFFVALY DYEARTSDDL SFKKGDRFQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCAGAG GGTCAATTGT GTTCTGCTCT TCCCTACTGA GCAAACAGTT TAAATGTGTA 60
ATTCAACATG CCAAAACCCT TCATTCTCAA AATGGTACTT CATTTACAAT GATAATGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0034334--P:adherens junction maintenance
GO:0060027--P:convergent extension involved in gastrulation
GO:0046777--P:protein autophosphorylation
GO:0045859--P:regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	87.73	0.00e+00	967.00
IUUC-Apl-004032	Anas platyrhynchos	90.64	0.00e+00	988.00
IUUC-Aca-004255	Anolis carolinensis	88.99	0.00e+00	989.00
IUUC-Ame-010954	Astyanax mexicanus	92.17	0.00e+00	1028.00
IUUC-Bta-013503	Bos taurus	87.34	0.00e+00	952.00
IUUC-Cja-019694	Callithrix jacchus	87.20	0.00e+00	955.00
IUUC-Cfa-020402	Canis familiaris	87.71	0.00e+00	970.00
IUUC-Cpo-022506	Cavia porcellus	87.16	0.00e+00	964.00
IUUC-Csa-023713	Chlorocebus sabaeus	87.75	0.00e+00	960.00
IUUC-Dre-027978	Danio rerio	91.97	0.00e+00	988.00
IUUC-Dno-029897	Dasypus novemcinctus	86.22	0.00e+00	834.00
IUUC-Dor-030202	Dipodomys ordii	92.95	0.00e+00	886.00
IUUC-Eca-034157	Equus caballus	86.97	0.00e+00	962.00
IUUC-Eeu-034950	Erinaceus europaeus	79.78	1.00e-159	555.00
IUUC-Fca-036233	Felis catus	88.07	0.00e+00	980.00
IUUC-Fal-037461	Ficedula albicollis	89.91	0.00e+00	1002.00
IUUC-Gmo-038929	Gadus morhua	87.84	0.00e+00	944.00
IUUC-Gga-041107	Gallus gallus	90.46	0.00e+00	990.00
IUUC-Gac-042321	Gasterosteus aculeatus	88.20	0.00e+00	971.00
IUUC-Hsa-047010	Homo sapiens	87.75	0.00e+00	971.00
IUUC-Lch-050239	Latimeria chalumnae	90.09	0.00e+00	1016.00
IUUC-Laf-053517	Loxodonta africana	87.34	0.00e+00	944.00
IUUC-Mcc-055626	Macaca mulatta	87.75	0.00e+00	962.00
IUUC-Mga-059310	Meleagris gallopavo	90.46	0.00e+00	990.00
IUUC-Mmr-061652	Microcebus murinus	86.06	0.00e+00	957.00
IUUC-Mdo-062963	Monodelphis domestica	86.79	0.00e+00	964.00
IUUC-Mmu-064128	Mus musculus	86.79	0.00e+00	966.00
IUUC-Mpu-065906	Mustela putorius furo	87.71	0.00e+00	970.00
IUUC-Mlu-067035	Myotis lucifugus	87.23	0.00e+00	962.00
IUUC-Nle-069041	Nomascus leucogenys	83.73	0.00e+00	912.00
IUUC-Opr-070299	Ochotona princeps	78.53	0.00e+00	842.00
IUUC-Ont-072337	Oreochromis niloticus	88.89	0.00e+00	980.00
IUUC-Oan-072997	Ornithorhynchus anatinus	94.52	0.00e+00	902.00
IUUC-Ocu-074171	Oryctolagus cuniculus	86.42	0.00e+00	962.00
IUUC-Ola-086619	Oryzias latipes	86.78	0.00e+00	981.00
IUUC-Oga-087957	Otolemur garnettii	86.79	0.00e+00	952.00
IUUC-Oar-089670	Ovis aries	86.24	0.00e+00	940.00
IUUC-Ptr-091352	Pan troglodytes	87.75	0.00e+00	971.00
IUUC-Pan-092202	Papio anubis	87.75	0.00e+00	962.00
IUUC-Psi-093310	Pelodiscus sinensis	90.09	0.00e+00	1007.00
IUUC-Pma-094232	Petromyzon marinus	84.99	0.00e+00	847.00
IUUC-Pfo-096137	Poecilia formosa	85.77	0.00e+00	954.00
IUUC-Pab-098301	Pongo abelii	91.41	0.00e+00	905.00
IUUC-Pva-102592	Pteropus vampyrus	84.04	0.00e+00	914.00
IUUC-Rno-105544	Rattus norvegicus	86.42	0.00e+00	957.00
IUUC-Sar-113364	Sorex araneus	81.65	0.00e+00	897.00
IUUC-Tgu-117380	Taeniopygia guttata	89.91	0.00e+00	1002.00
IUUC-Tru-117784	Takifugu rubripes	88.52	0.00e+00	980.00
IUUC-Tni-120433	Tetraodon nigroviridis	85.92	0.00e+00	955.00
IUUC-Ttr-128893	Tursiops truncatus	86.97	0.00e+00	962.00
IUUC-Vpa-130060	Vicugna pacos	86.79	0.00e+00	959.00
IUUC-Xtr-132322	Xenopus tropicalis	89.54	0.00e+00	992.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence