iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005144

Ensembl Protein ID

ENSACAP00000002867.2

UniProt Accession

G1KBC7; G1KBC7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002919.3	ENSACAT00000002938.3	ENSACAP00000002867.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	60.81	0.00e+00	1125.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MENQRGGETT IQQTATAACR SSFVSLLKVH RELLVSKVRN TQCLIDNLLK NEYFSTEDAE 60
IAAQYPTQAD KVRKILDLAQ SKGEEVAEYC IYVLQQVADA YYELHPWLEE IGFHPSEVIS 120

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Nucleotide Sequence
(Fasta)

GGGAAGTGTT CGGCTTGTGA TTTTGTGATA CGAAATCCAG CATATCTATC TTGTTTACAA 60
TAAGCGCGTT CTCCTCCTGG GCCACTTCCT GCGGCCGCCC TGCAGGGGGC GCTGCGAACT 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

KEGG

acs:100561251

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	60.15	0.00e+00	1018.00
IUUC-Apl-003908	Anas platyrhynchos	72.90	0.00e+00	1360.00
IUUC-Acl-008366	Aspergillus clavatus	37.84	3.20e+00	26.20
IUUC-Ame-010829	Astyanax mexicanus	52.53	0.00e+00	929.00
IUUC-Bta-013358	Bos taurus	62.65	0.00e+00	1099.00
IUUC-Cja-019392	Callithrix jacchus	59.42	0.00e+00	1052.00
IUUC-Cfa-020776	Canis familiaris	60.92	0.00e+00	1090.00
IUUC-Cpo-021393	Cavia porcellus	58.27	0.00e+00	1034.00
IUUC-Csa-023872	Chlorocebus sabaeus	60.60	0.00e+00	1087.00
IUUC-Cho-024569	Choloepus hoffmanni	53.33	2.00e-119	422.00
IUUC-Dre-027478	Danio rerio	51.34	0.00e+00	899.00
IUUC-Dno-029231	Dasypus novemcinctus	62.42	0.00e+00	1128.00
IUUC-Dor-030251	Dipodomys ordii	43.95	3.00e-121	429.00
IUUC-Ete-032484	Echinops telfairi	54.44	5.00e-144	505.00
IUUC-Eca-033564	Equus caballus	61.78	0.00e+00	1122.00
IUUC-Eeu-034456	Erinaceus europaeus	48.76	7.00e-95	341.00
IUUC-Fca-036372	Felis catus	61.02	0.00e+00	1104.00
IUUC-Fal-037418	Ficedula albicollis	72.41	0.00e+00	1351.00
IUUC-Gmo-038740	Gadus morhua	51.84	0.00e+00	920.00
IUUC-Gga-040775	Gallus gallus	72.14	0.00e+00	1357.00
IUUC-Gac-041612	Gasterosteus aculeatus	51.99	0.00e+00	916.00
IUUC-Ggo-045161	Gorilla gorilla	59.32	0.00e+00	883.00
IUUC-Hsa-046886	Homo sapiens	60.81	0.00e+00	1085.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	59.17	0.00e+00	1120.00
IUUC-Lch-049764	Latimeria chalumnae	59.93	0.00e+00	1032.00
IUUC-Loc-052143	Lepisosteus oculatus	56.08	0.00e+00	1033.00
IUUC-Laf-053503	Loxodonta africana	61.02	0.00e+00	1120.00
IUUC-Mcc-054992	Macaca mulatta	60.49	0.00e+00	1085.00
IUUC-Meu-056406	Macropus eugenii	53.49	0.00e+00	919.00
IUUC-Mga-059351	Meleagris gallopavo	72.19	0.00e+00	1348.00
IUUC-Mmr-061537	Microcebus murinus	61.37	0.00e+00	1041.00
IUUC-Mdo-061832	Monodelphis domestica	54.62	0.00e+00	925.00
IUUC-Mmu-064282	Mus musculus	59.45	0.00e+00	1096.00
IUUC-Mpu-066399	Mustela putorius furo	61.30	0.00e+00	1114.00
IUUC-Mlu-067265	Myotis lucifugus	60.38	0.00e+00	1078.00
IUUC-Nle-069078	Nomascus leucogenys	60.60	0.00e+00	1076.00
IUUC-Opr-070946	Ochotona princeps	54.22	0.00e+00	955.00
IUUC-Ont-071355	Oreochromis niloticus	51.78	0.00e+00	926.00
IUUC-Oan-072937	Ornithorhynchus anatinus	64.83	0.00e+00	1172.00
IUUC-Ocu-073815	Oryctolagus cuniculus	60.02	0.00e+00	1100.00
IUUC-Ola-087381	Oryzias latipes	50.93	0.00e+00	891.00
IUUC-Oga-088725	Otolemur garnettii	61.11	0.00e+00	1102.00
IUUC-Oar-090401	Ovis aries	61.79	0.00e+00	1123.00
IUUC-Ptr-090590	Pan troglodytes	60.71	0.00e+00	1083.00
IUUC-Pan-091765	Papio anubis	60.49	0.00e+00	1084.00
IUUC-Psi-093182	Pelodiscus sinensis	74.26	0.00e+00	1389.00
IUUC-Pma-094167	Petromyzon marinus	28.42	1.00e-44	174.00
IUUC-Ppa-095344	Physcomitrella patens	22.33	6.00e-02	33.10
IUUC-Pfo-097422	Poecilia formosa	50.64	0.00e+00	901.00
IUUC-Pab-098289	Pongo abelii	60.81	0.00e+00	1082.00
IUUC-Pca-100165	Procavia capensis	55.51	0.00e+00	745.00
IUUC-Pva-102943	Pteropus vampyrus	60.82	0.00e+00	1097.00
IUUC-Rno-104930	Rattus norvegicus	59.62	0.00e+00	1092.00
IUUC-Sha-106800	Sarcophilus harrisii	42.28	0.00e+00	634.00
IUUC-Sar-113205	Sorex araneus	58.17	2.00e-147	516.00
IUUC-Ssc-115910	Sus scrofa	61.25	0.00e+00	962.00
IUUC-Tgu-117179	Taeniopygia guttata	74.01	0.00e+00	1365.00
IUUC-Tru-118220	Takifugu rubripes	49.68	0.00e+00	884.00
IUUC-Tsy-119418	Tarsius syrichta	57.84	0.00e+00	843.00
IUUC-Tni-120033	Tetraodon nigroviridis	52.35	9.00e-66	243.00
IUUC-Tbe-127308	Tupaia belangeri	63.76	1.00e-141	497.00
IUUC-Ttr-129233	Tursiops truncatus	60.82	0.00e+00	1105.00
IUUC-Vpa-130620	Vicugna pacos	52.23	2.00e-81	297.00
IUUC-Xtr-132075	Xenopus tropicalis	54.79	0.00e+00	1008.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence