iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062484

UUCD1 version

UUC-MoD-00339

Ensembl Protein ID

ENSMODP00000024817.2

UniProt Accession

F6W6A0; F6W6A0_MONDO

Protein Name

Uncharacterized protein

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019891.4	ENSMODT00000025258.3	ENSMODP00000024817.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-07	32.0	99	132

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 99   GHRRTPWCVTFhPTipGLIASGCLDGEVRIWDLH 132
           6777779*****66679***************97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

WCLRAMKVVP EKNAVRILWG RERGTRALGA QRLLQELVED KTRWMKDWES RKVELPDSPR 60
STFLLAFSPD RTLMASTHVN HNIYITEVKT GKCVHSLVGH RRTPWCVTFH PTIPGLIASG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTGCCTAA GAGCCATGAA GGTTGTCCCC GAGAAGAATG CTGTCCGGAT ACTCTGGGGT 60
CGAGAAAGAG GCACACGGGC CTTGGGGGCT CAGCGGCTTC TGCAGGAGCT GGTGGAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	74.31	0.00e+00	1348.00
IUUC-Atr-002557	Amborella trichopoda	37.56	7.00e-31	129.00
IUUC-Apl-004186	Anas platyrhynchos	74.11	0.00e+00	1693.00
IUUC-Aca-004419	Anolis carolinensis	67.66	0.00e+00	1526.00
IUUC-Aly-006308	Arabidopsis lyrata	36.70	4.00e-28	119.00
IUUC-Ath-007656	Arabidopsis thaliana	43.51	4.00e-28	119.00
IUUC-Ame-011354	Astyanax mexicanus	49.28	4.00e-168	585.00
IUUC-Bta-012455	Bos taurus	74.86	0.00e+00	1714.00
IUUC-Bdi-014580	Brachypodium distachyon	40.61	1.00e-29	125.00
IUUC-Bol-016094	Brassica oleracea	44.16	1.00e-28	121.00
IUUC-Bra-017308	Brassica rapa	44.81	1.00e-29	124.00
IUUC-Cja-019073	Callithrix jacchus	94.16	5.00e-147	514.00
IUUC-Cfa-020994	Canis familiaris	72.35	0.00e+00	1128.00
IUUC-Cpo-022101	Cavia porcellus	76.42	0.00e+00	1660.00
IUUC-Csa-023273	Chlorocebus sabaeus	72.47	0.00e+00	1182.00
IUUC-Cin-025567	Ciona intestinalis	59.17	3.00e-55	209.00
IUUC-Csv-026005	Ciona savignyi	55.62	7.00e-55	206.00
IUUC-Dre-028282	Danio rerio	52.24	4.00e-173	602.00
IUUC-Dno-029948	Dasypus novemcinctus	74.73	0.00e+00	1700.00
IUUC-Dor-030568	Dipodomys ordii	80.08	0.00e+00	1044.00
IUUC-Ete-032864	Echinops telfairi	75.44	0.00e+00	1642.00
IUUC-Eca-034392	Equus caballus	72.19	0.00e+00	1183.00
IUUC-Eeu-034440	Erinaceus europaeus	77.04	0.00e+00	1052.00
IUUC-Fca-035359	Felis catus	73.18	0.00e+00	1674.00
IUUC-Fal-037483	Ficedula albicollis	74.16	0.00e+00	1740.00
IUUC-Gmo-039343	Gadus morhua	60.54	3.00e-163	569.00
IUUC-Gga-040787	Gallus gallus	79.43	0.00e+00	1054.00
IUUC-Gac-041321	Gasterosteus aculeatus	53.38	5.00e-178	618.00
IUUC-Gma-044022	Glycine max	36.63	5.00e-31	129.00
IUUC-Ggo-044775	Gorilla gorilla	69.10	0.00e+00	733.00
IUUC-Hsa-045708	Homo sapiens	74.94	0.00e+00	1729.00
IUUC-Hvu-047536	Hordeum vulgare	41.07	1.00e-30	128.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	79.60	0.00e+00	1050.00
IUUC-Lch-050255	Latimeria chalumnae	62.99	0.00e+00	1224.00
IUUC-Lpe-050684	Leersia perrieri	40.70	3.00e-31	130.00
IUUC-Loc-052881	Lepisosteus oculatus	61.01	0.00e+00	1294.00
IUUC-Laf-053342	Loxodonta africana	76.62	0.00e+00	956.00
IUUC-Mcc-055848	Macaca mulatta	74.40	0.00e+00	1740.00
IUUC-Meu-056320	Macropus eugenii	80.80	0.00e+00	1752.00
IUUC-Mtr-058484	Medicago truncatula	37.07	2.00e-30	127.00
IUUC-Mga-059401	Meleagris gallopavo	75.02	0.00e+00	1429.00
IUUC-Mmr-061037	Microcebus murinus	75.91	0.00e+00	1685.00
IUUC-Mmu-064090	Mus musculus	73.69	0.00e+00	1685.00
IUUC-Mac-065308	Musa acuminata	40.54	2.00e-30	127.00
IUUC-Mpu-066165	Mustela putorius furo	73.47	0.00e+00	1130.00
IUUC-Mlu-068038	Myotis lucifugus	74.45	0.00e+00	1725.00
IUUC-Nle-069361	Nomascus leucogenys	76.61	0.00e+00	1503.00
IUUC-Opr-070360	Ochotona princeps	75.76	0.00e+00	978.00
IUUC-Ont-071277	Oreochromis niloticus	53.68	0.00e+00	629.00
IUUC-Oan-073623	Ornithorhynchus anatinus	72.74	0.00e+00	855.00
IUUC-Ocu-074600	Oryctolagus cuniculus	75.18	0.00e+00	1040.00
IUUC-Oba-075024	Oryza barthii	37.21	1.00e-33	138.00
IUUC-Obr-076172	Oryza brachyantha	37.21	6.00e-34	139.00
IUUC-Ogl-077411	Oryza glaberrima	37.21	1.00e-33	138.00
IUUC-Ogu-078025	Oryza glumaepatula	37.21	2.00e-33	138.00
IUUC-Oni-082463	Oryza nivara	37.21	1.00e-33	139.00
IUUC-Opu-084041	Oryza punctata	37.21	3.00e-33	137.00
IUUC-Oru-085075	Oryza rufipogon	41.71	5.00e-33	136.00
IUUC-Osa-085781	Oryza sativa	37.21	1.00e-33	138.00
IUUC-Ola-086729	Oryzias latipes	54.82	0.00e+00	650.00
IUUC-Olu-087735	Ostreococcus lucimarinus	38.97	2.00e-24	107.00
IUUC-Oga-089113	Otolemur garnettii	73.71	0.00e+00	1628.00
IUUC-Oar-090171	Ovis aries	76.90	0.00e+00	1649.00
IUUC-Ptr-090970	Pan troglodytes	75.02	0.00e+00	1731.00
IUUC-Pan-092778	Papio anubis	72.81	0.00e+00	1189.00
IUUC-Psi-093571	Pelodiscus sinensis	72.67	0.00e+00	1683.00
IUUC-Pma-094563	Petromyzon marinus	75.10	8.00e-105	372.00
IUUC-Ppa-095832	Physcomitrella patens	35.32	1.00e-29	125.00
IUUC-Pfo-097365	Poecilia formosa	53.27	9.00e-180	624.00
IUUC-Pab-098647	Pongo abelii	78.38	0.00e+00	1773.00
IUUC-Pop-099742	Populus trichocarpa	40.11	2.00e-31	130.00
IUUC-Pca-101035	Procavia capensis	76.98	0.00e+00	1001.00
IUUC-Ppe-101783	Prunus persica	42.54	1.00e-31	131.00
IUUC-Pva-103187	Pteropus vampyrus	81.75	0.00e+00	789.00
IUUC-Rno-105701	Rattus norvegicus	73.76	0.00e+00	1670.00
IUUC-Sha-107612	Sarcophilus harrisii	83.14	0.00e+00	1910.00
IUUC-Smo-109107	Selaginella moellendorffii	39.08	4.00e-28	119.00
IUUC-Sit-110786	Setaria italica	39.66	2.00e-32	134.00
IUUC-Sly-110859	Solanum lycopersicum	36.67	6.00e-32	132.00
IUUC-Stu-112031	Solanum tuberosum	37.14	4.00e-32	133.00
IUUC-Sar-113242	Sorex araneus	80.20	0.00e+00	926.00
IUUC-Ssc-116094	Sus scrofa	75.23	0.00e+00	1721.00
IUUC-Tru-118308	Takifugu rubripes	53.39	0.00e+00	632.00
IUUC-Tsy-119552	Tarsius syrichta	78.96	0.00e+00	1499.00
IUUC-Tca-121616	Theobroma cacao	37.91	2.00e-32	134.00
IUUC-Tae-124768	Triticum aestivum	40.48	1.00e-29	124.00
IUUC-Tur-126480	Triticum urartu	40.48	5.00e-30	126.00
IUUC-Tbe-127902	Tupaia belangeri	78.21	0.00e+00	826.00
IUUC-Ttr-129278	Tursiops truncatus	79.69	0.00e+00	1573.00
IUUC-Vpa-130741	Vicugna pacos	72.37	0.00e+00	1232.00
IUUC-Vvi-131437	Vitis vinifera	40.59	3.00e-31	130.00
IUUC-Xtr-132247	Xenopus tropicalis	57.83	0.00e+00	1119.00
IUUC-Xma-134277	Xiphophorus maculatus	54.43	0.00e+00	638.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence