iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052667

Ensembl Protein ID

ENSLOCP00000002614.1

UniProt Accession

W5M2K6; W5M2K6_LEPOC

Genbank Protein ID

ENSLOCP00000002614

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01025064

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000002227.1	ENSLOCT00000002620.1	ENSLOCP00000002614.1
ENSLOCG00000002227.1	ENSLOCT00000002644.1	ENSLOCP00000002638.1
ENSLOCG00000002227.1	ENSLOCT00000002663.1	ENSLOCP00000002657.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.10e-83	279.5	1581	1979

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l                 k         +                             
   Q: 1581 VGLKNAGATCYMNSVIQQLYMIPPIRNGILAiegtgsdvdddmsgdeK---------Qdnetnvdprdevfsyhhqyeekpslskse 1658
           6******************************98888877766655441.........033333445566777777766666666666 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l  s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1659 drKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1725
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d++e+++k + leg+n+y+cekc+kk
   Q: 1726 ------KALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSMEQYVKGDLLEGANAYHCEKCNKK 1801
           ......67999******************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts..................peekqke........k 275
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                   +     e        +
   Q: 1802 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegddvhpenqviqN-----EpteneppgS 1883
           *****************************************************7777777777766665551.....044555666* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvkn......ekgkWllfdDskVtevkeeevleetg...........................st 329
           +kY+L++v+vHsG++s+GHY++y+ +      ek++W++fdD  Vte+k+++ +e+++                           ++
   Q: 1884 TKYRLVGVLVHSGQASGGHYYSYIIQrnggdgEKNRWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqkrwWN 1970
           **************************6666655666*******************9999**************************** PP
   S: 330  aYvlfYkrr 338
           aY+lfY+r+
   Q: 1971 AYILFYERM 1979
           *******96 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MTATTRGSPV GGNESQGQAP DGQSQPPLPQ NQTSSPNSSN ENSPVSPPDE QGQGDGHPQL 60
EEEEEPAFPH TDLAKLDDMI NRPRWVVPVL PKGELEVLLE AAIDLSKNGL DVKCEACQRF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTATGCAAT GGTCTCTGCA AAACATCCTG TGCTTCAGGT GGTGCTTTCT TCTACAGACG 60
CATGCTGGTT CTCCATCATT GTTGAGGAGG CAATAATTTC TTCTCTCACG ACAACAACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	89.84	0.00e+00	4667.00
IUUC-Apl-003592	Anas platyrhynchos	91.83	0.00e+00	4739.00
IUUC-Aca-004939	Anolis carolinensis	91.75	0.00e+00	4706.00
IUUC-Ame-011772	Astyanax mexicanus	93.74	0.00e+00	4841.00
IUUC-Bta-012775	Bos taurus	89.50	0.00e+00	4629.00
IUUC-Cja-019464	Callithrix jacchus	89.16	0.00e+00	4568.00
IUUC-Cfa-020569	Canis familiaris	90.42	0.00e+00	2998.00
IUUC-Csa-023405	Chlorocebus sabaeus	89.53	0.00e+00	4617.00
IUUC-Cho-024524	Choloepus hoffmanni	88.18	0.00e+00	769.00
IUUC-Cin-025551	Ciona intestinalis	63.50	6.00e-141	493.00
IUUC-Csv-025956	Ciona savignyi	53.76	0.00e+00	2532.00
IUUC-Dre-028329	Danio rerio	93.17	0.00e+00	4841.00
IUUC-Dno-028936	Dasypus novemcinctus	89.80	0.00e+00	4666.00
IUUC-Dor-030352	Dipodomys ordii	85.63	0.00e+00	2089.00
IUUC-Dme-032160	Drosophila melanogaster	47.92	0.00e+00	2199.00
IUUC-Ete-032287	Echinops telfairi	88.08	0.00e+00	2574.00
IUUC-Eca-033352	Equus caballus	89.92	0.00e+00	4680.00
IUUC-Eeu-034907	Erinaceus europaeus	81.72	0.00e+00	1732.00
IUUC-Fca-035458	Felis catus	90.18	0.00e+00	4691.00
IUUC-Fal-036924	Ficedula albicollis	94.00	0.00e+00	4665.00
IUUC-Gmo-039578	Gadus morhua	91.98	0.00e+00	4656.00
IUUC-Gga-040978	Gallus gallus	92.09	0.00e+00	4745.00
IUUC-Gac-041970	Gasterosteus aculeatus	92.72	0.00e+00	4757.00
IUUC-Ggo-045575	Gorilla gorilla	90.07	0.00e+00	4655.00
IUUC-Hsa-046295	Homo sapiens	90.11	0.00e+00	4658.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	89.72	0.00e+00	4660.00
IUUC-Lch-050493	Latimeria chalumnae	91.79	0.00e+00	4677.00
IUUC-Laf-054094	Loxodonta africana	89.39	0.00e+00	4682.00
IUUC-Mcc-054861	Macaca mulatta	88.69	0.00e+00	4605.00
IUUC-Meu-056849	Macropus eugenii	79.98	0.00e+00	1383.00
IUUC-Mga-060159	Meleagris gallopavo	92.05	0.00e+00	4743.00
IUUC-Mmr-060732	Microcebus murinus	89.80	0.00e+00	4667.00
IUUC-Mdo-062274	Monodelphis domestica	92.09	0.00e+00	4798.00
IUUC-Mmu-064056	Mus musculus	89.19	0.00e+00	4637.00
IUUC-Mpu-066669	Mustela putorius furo	89.88	0.00e+00	4672.00
IUUC-Mlu-067516	Myotis lucifugus	89.46	0.00e+00	4643.00
IUUC-Nle-069664	Nomascus leucogenys	90.51	0.00e+00	3414.00
IUUC-Opr-070185	Ochotona princeps	82.91	0.00e+00	758.00
IUUC-Ont-072119	Oreochromis niloticus	92.60	0.00e+00	4772.00
IUUC-Oan-073154	Ornithorhynchus anatinus	91.87	0.00e+00	4776.00
IUUC-Ocu-074485	Oryctolagus cuniculus	90.45	0.00e+00	4716.00
IUUC-Ola-086350	Oryzias latipes	91.61	0.00e+00	4658.00
IUUC-Oga-088328	Otolemur garnettii	89.99	0.00e+00	4729.00
IUUC-Oar-090098	Ovis aries	89.99	0.00e+00	4667.00
IUUC-Pan-091741	Papio anubis	90.70	0.00e+00	3576.00
IUUC-Psi-093040	Pelodiscus sinensis	91.87	0.00e+00	4729.00
IUUC-Pfo-096871	Poecilia formosa	91.81	0.00e+00	4751.00
IUUC-Pab-098374	Pongo abelii	89.57	0.00e+00	4617.00
IUUC-Pca-100801	Procavia capensis	81.88	0.00e+00	2248.00
IUUC-Pva-102992	Pteropus vampyrus	84.65	0.00e+00	2250.00
IUUC-Rno-105377	Rattus norvegicus	89.30	0.00e+00	4645.00
IUUC-Sha-106648	Sarcophilus harrisii	89.69	0.00e+00	4623.00
IUUC-Smo-108879	Selaginella moellendorffii	27.96	0.00e+00	809.00
IUUC-Sar-113729	Sorex araneus	89.94	0.00e+00	2900.00
IUUC-Ssc-116261	Sus scrofa	86.60	0.00e+00	4570.00
IUUC-Tgu-117126	Taeniopygia guttata	91.86	0.00e+00	4743.00
IUUC-Tru-117676	Takifugu rubripes	92.07	0.00e+00	4752.00
IUUC-Tsy-119209	Tarsius syrichta	79.34	0.00e+00	1611.00
IUUC-Tni-120207	Tetraodon nigroviridis	87.67	0.00e+00	2117.00
IUUC-Tbe-128033	Tupaia belangeri	85.43	0.00e+00	949.00
IUUC-Ttr-128742	Tursiops truncatus	88.31	0.00e+00	4576.00
IUUC-Vpa-130581	Vicugna pacos	86.29	0.00e+00	4432.00
IUUC-Xtr-132145	Xenopus tropicalis	91.22	0.00e+00	4742.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence