iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071954

Ensembl Protein ID

ENSONIP00000007826.1

UniProt Accession

I3JG35; I3JG35_ORENI

Genbank Protein ID

ENSONIP00000007826

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01025135

Gene Name

cbl (1 of many); cbl

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000006212.1	ENSONIT00000007831.1	ENSONIP00000007826.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.8	365	406

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w   + s+ +   CP Cr
   Q: 365  CKICAENDKD-VKIEPCGHLMCTSCLTAW---QESEGQGTGCPFCR 406
           99********.******************...333666666****8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAGNLKKGGG IIGMMKDAFQ PHHHHLHSHH QPGAVDKKTV EKCWKLMDKV VRLCQNPKLA 60
LKNSPPYILD LLPDTYQHLR TILSRYEGKM ETLGDNEYFR VFMENLTKKT KQTISLFKEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGGA ACCTGAAGAA AGGCGGGGGG ATCATCGGAA TGATGAAGGA TGCCTTCCAG 60
CCACACCATC ACCACCTTCA CTCCCATCAC CAGCCCGGGG CCGTGGACAA AAAGACGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002357	Ailuropoda melanoleuca	68.54	0.00e+00	1050.00
IUUC-Apl-004041	Anas platyrhynchos	71.23	0.00e+00	1107.00
IUUC-Aca-004899	Anolis carolinensis	70.24	0.00e+00	1061.00
IUUC-Ame-010746	Astyanax mexicanus	67.11	0.00e+00	759.00
IUUC-Bta-012759	Bos taurus	69.30	0.00e+00	1093.00
IUUC-Cel-018674	Caenorhabditis elegans	55.15	4.00e-134	471.00
IUUC-Cja-019207	Callithrix jacchus	68.83	0.00e+00	1096.00
IUUC-Cfa-020897	Canis familiaris	67.70	0.00e+00	1075.00
IUUC-Cpo-021453	Cavia porcellus	69.37	0.00e+00	1082.00
IUUC-Csa-023136	Chlorocebus sabaeus	69.22	0.00e+00	1088.00
IUUC-Cho-024282	Choloepus hoffmanni	60.93	0.00e+00	905.00
IUUC-Cin-025574	Ciona intestinalis	70.74	2.00e-178	618.00
IUUC-Csv-025938	Ciona savignyi	69.11	1.00e-172	598.00
IUUC-Dre-027644	Danio rerio	78.42	0.00e+00	1174.00
IUUC-Dno-030025	Dasypus novemcinctus	68.38	0.00e+00	1060.00
IUUC-Dme-032213	Drosophila melanogaster	73.86	0.00e+00	642.00
IUUC-Eca-033900	Equus caballus	69.05	0.00e+00	1073.00
IUUC-Eeu-035142	Erinaceus europaeus	72.50	0.00e+00	770.00
IUUC-Fca-035455	Felis catus	66.77	0.00e+00	1102.00
IUUC-Fal-037182	Ficedula albicollis	89.69	0.00e+00	850.00
IUUC-Gmo-038698	Gadus morhua	94.62	0.00e+00	962.00
IUUC-Gga-040438	Gallus gallus	72.20	0.00e+00	1130.00
IUUC-Gac-042166	Gasterosteus aculeatus	81.41	0.00e+00	1189.00
IUUC-Ggo-045618	Gorilla gorilla	69.08	0.00e+00	1094.00
IUUC-Hsa-046177	Homo sapiens	69.19	0.00e+00	1092.00
IUUC-Itr-048795	Ictidomys tridecemlineatus	77.80	0.00e+00	780.00
IUUC-Lch-050095	Latimeria chalumnae	81.49	0.00e+00	986.00
IUUC-Loc-052570	Lepisosteus oculatus	78.84	0.00e+00	1234.00
IUUC-Laf-054008	Loxodonta africana	68.47	0.00e+00	1118.00
IUUC-Mcc-054676	Macaca mulatta	69.22	0.00e+00	1088.00
IUUC-Mga-059239	Meleagris gallopavo	71.85	0.00e+00	1150.00
IUUC-Mmr-060907	Microcebus murinus	66.42	0.00e+00	1090.00
IUUC-Mdo-062595	Monodelphis domestica	69.97	0.00e+00	1075.00
IUUC-Mmu-063725	Mus musculus	68.83	0.00e+00	1145.00
IUUC-Mpu-066771	Mustela putorius furo	68.02	0.00e+00	1095.00
IUUC-Mlu-067206	Myotis lucifugus	65.68	0.00e+00	887.00
IUUC-Nle-069285	Nomascus leucogenys	68.02	0.00e+00	1033.00
IUUC-Opr-071026	Ochotona princeps	69.35	0.00e+00	1076.00
IUUC-Ocu-074657	Oryctolagus cuniculus	68.88	0.00e+00	1038.00
IUUC-Ola-087165	Oryzias latipes	82.08	0.00e+00	1337.00
IUUC-Oga-088198	Otolemur garnettii	72.75	0.00e+00	934.00
IUUC-Oar-090258	Ovis aries	69.49	0.00e+00	1046.00
IUUC-Ptr-090710	Pan troglodytes	69.19	0.00e+00	1092.00
IUUC-Pan-092785	Papio anubis	69.44	0.00e+00	1088.00
IUUC-Pma-094249	Petromyzon marinus	76.03	5.00e-124	437.00
IUUC-Pfo-096990	Poecilia formosa	83.76	0.00e+00	1265.00
IUUC-Pab-098526	Pongo abelii	69.37	0.00e+00	1095.00
IUUC-Pva-102352	Pteropus vampyrus	86.13	0.00e+00	828.00
IUUC-Rno-105876	Rattus norvegicus	68.12	0.00e+00	1124.00
IUUC-Sha-107588	Sarcophilus harrisii	67.41	0.00e+00	929.00
IUUC-Sar-112959	Sorex araneus	67.92	0.00e+00	1063.00
IUUC-Ssc-115261	Sus scrofa	68.19	0.00e+00	1107.00
IUUC-Tgu-116580	Taeniopygia guttata	69.39	0.00e+00	1076.00
IUUC-Tru-118731	Takifugu rubripes	81.19	0.00e+00	1316.00
IUUC-Tsy-118982	Tarsius syrichta	58.72	0.00e+00	665.00
IUUC-Tni-120725	Tetraodon nigroviridis	79.98	0.00e+00	1247.00
IUUC-Tbe-128018	Tupaia belangeri	80.45	0.00e+00	937.00
IUUC-Ttr-128927	Tursiops truncatus	69.17	0.00e+00	1133.00
IUUC-Vpa-130369	Vicugna pacos	69.22	0.00e+00	1019.00
IUUC-Xtr-132474	Xenopus tropicalis	67.31	0.00e+00	1063.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence