iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028562

Ensembl Protein ID

ENSDARP00000134787.1

UniProt Accession

Q6DHF1; Q6DHF1_DANRE

Genbank Protein ID

AAH76023.1

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

CR847546

Gene Name

ing2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000104907.1	ENSDART00000160066.1	ENSDARP00000134787.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.60e-09	36.2	211	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 211  TYC-LCEQVSYGE--MIGCDNeqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 257
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MLGHYPNVEK SQLVNYVEDY LECVESLPLD IQRNVSLLRE IDTKYQEVLK EVDEIYEKYK 60
KESDSGQRKR LQIQLQRALI SSQELGDEKI HVVTQMMEVV ENRSRQIEAH SPCFLEPGDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCCTGCGC ATGCGCAGTC TCGATAGTTT TGTTTGAAGG AGTTCTCGTA GCCAGAGAAG 60
ACTGAATTTG GAAAGAGTGG CTCTCCACAA GGTTGCCAAC TAACAACATA ATTTAAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

KEGG

dre:436721

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	72.06	6.00e-81	293.00
IUUC-Apl-003910	Anas platyrhynchos	58.46	6.00e-73	267.00
IUUC-Aca-004990	Anolis carolinensis	69.78	4.00e-85	308.00
IUUC-Ame-011426	Astyanax mexicanus	85.71	3.00e-106	377.00
IUUC-Bta-012721	Bos taurus	70.96	2.00e-79	289.00
IUUC-Cja-018960	Callithrix jacchus	70.96	6.00e-72	263.00
IUUC-Cfa-020869	Canis familiaris	65.07	2.00e-80	292.00
IUUC-Cpo-021414	Cavia porcellus	71.91	2.00e-79	288.00
IUUC-Csa-023304	Chlorocebus sabaeus	71.79	1.00e-72	266.00
IUUC-Cho-024577	Choloepus hoffmanni	56.71	6.00e-55	207.00
IUUC-Dno-029945	Dasypus novemcinctus	63.60	6.00e-79	287.00
IUUC-Dor-030141	Dipodomys ordii	70.59	5.00e-78	284.00
IUUC-Ete-032709	Echinops telfairi	65.81	3.00e-87	315.00
IUUC-Eca-033432	Equus caballus	66.91	2.00e-79	289.00
IUUC-Eeu-035285	Erinaceus europaeus	68.37	2.00e-64	238.00
IUUC-Fca-036467	Felis catus	69.12	4.00e-80	291.00
IUUC-Fal-036838	Ficedula albicollis	58.09	3.00e-72	265.00
IUUC-Gmo-038748	Gadus morhua	69.93	3.00e-97	348.00
IUUC-Gga-040619	Gallus gallus	59.19	2.00e-73	268.00
IUUC-Gac-041403	Gasterosteus aculeatus	69.86	9.00e-102	363.00
IUUC-Ggo-045481	Gorilla gorilla	55.56	6.00e-54	204.00
IUUC-Hsa-045837	Homo sapiens	71.79	1.00e-72	266.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	70.59	2.00e-78	285.00
IUUC-Lch-049965	Latimeria chalumnae	69.06	7.00e-94	336.00
IUUC-Loc-052038	Lepisosteus oculatus	62.93	2.00e-72	265.00
IUUC-Laf-054126	Loxodonta africana	58.82	2.00e-73	269.00
IUUC-Mcc-055031	Macaca mulatta	55.79	1.00e-53	203.00
IUUC-Meu-056470	Macropus eugenii	73.96	3.00e-88	318.00
IUUC-Mga-059570	Meleagris gallopavo	69.23	1.00e-70	259.00
IUUC-Mmr-061385	Microcebus murinus	70.96	3.00e-72	265.00
IUUC-Mdo-062144	Monodelphis domestica	73.96	2.00e-88	318.00
IUUC-Mmu-063215	Mus musculus	69.85	1.00e-78	286.00
IUUC-Mpu-065749	Mustela putorius furo	69.08	3.00e-72	264.00
IUUC-Mlu-067586	Myotis lucifugus	54.07	4.00e-74	271.00
IUUC-Nle-069122	Nomascus leucogenys	58.46	3.00e-72	265.00
IUUC-Opr-070835	Ochotona princeps	75.00	4.00e-36	144.00
IUUC-Ont-071524	Oreochromis niloticus	69.29	2.00e-101	362.00
IUUC-Oan-073023	Ornithorhynchus anatinus	55.93	2.00e-73	269.00
IUUC-Ocu-074870	Oryctolagus cuniculus	71.32	7.00e-80	290.00
IUUC-Ola-086891	Oryzias latipes	58.58	7.00e-77	280.00
IUUC-Oga-088336	Otolemur garnettii	71.32	1.00e-72	266.00
IUUC-Oar-090136	Ovis aries	68.01	3.00e-79	288.00
IUUC-Ptr-090589	Pan troglodytes	58.82	4.00e-73	267.00
IUUC-Pan-092819	Papio anubis	71.79	1.00e-72	266.00
IUUC-Psi-093266	Pelodiscus sinensis	59.56	2.00e-74	272.00
IUUC-Pma-094265	Petromyzon marinus	71.23	3.00e-31	127.00
IUUC-Pfo-096633	Poecilia formosa	71.99	6.00e-93	333.00
IUUC-Pab-098346	Pongo abelii	71.79	2.00e-72	265.00
IUUC-Pca-100278	Procavia capensis	67.42	2.00e-85	308.00
IUUC-Pva-103190	Pteropus vampyrus	68.75	6.00e-80	290.00
IUUC-Rno-104940	Rattus norvegicus	66.91	2.00e-77	282.00
IUUC-Sha-107533	Sarcophilus harrisii	73.58	2.00e-87	315.00
IUUC-Sar-113630	Sorex araneus	67.91	1.00e-63	236.00
IUUC-Ssc-115734	Sus scrofa	68.75	7.00e-80	290.00
IUUC-Tgu-116822	Taeniopygia guttata	57.72	4.00e-72	264.00
IUUC-Tru-118168	Takifugu rubripes	67.26	8.00e-91	326.00
IUUC-Tsy-119494	Tarsius syrichta	71.00	6.00e-58	216.00
IUUC-Tni-119663	Tetraodon nigroviridis	67.97	3.00e-93	334.00
IUUC-Ttr-128442	Tursiops truncatus	67.44	1.00e-63	235.00
IUUC-Vpa-130063	Vicugna pacos	70.96	4.00e-79	287.00
IUUC-Xtr-132348	Xenopus tropicalis	59.78	6.00e-59	221.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence