iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098173

UUCD1 version

UUC-PoA-01001

Ensembl Protein ID

ENSPPYP00000011372.2

UniProt Accession

A0A075B7H4; A0A075B7H4_PONAB

Genbank Protein ID

ENSPPYP00000011372

Protein Name

SUMO-activating enzyme subunit 1

Genbank Nucleotide ID

ABGA01395304

Gene Name

SAE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000010168.2	ENSPPYT00000011814.2	ENSPPYP00000011372.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.20e-90	304.8	55	371

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn 89
           YDRQirlwG eaq++l+ ++vllvG++glG+E++KnL+laGv+ +t++D+++v+ +++++qFL+r  +vg+++Ae+++e++++lnp+v+
   Q: 55   YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVD 143
           ***************************************************************************************** PP
   S: 90   veaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlke 178
           v++++e+i+++ e+  Ff++fd V+l++++r+   kv+++c+++++++++++++G++G++                       f +l+e
   Q: 144  VKVDTEDIEKKPES--FFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYT-----------------------FANLGE 207
           **************..********************************************.......................****** PP
   S: 179  tpnaaehtiewavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtk 267
           ++ ++e+t +        ++ e+g++++++klds+e++++k+kv                                             
   Q: 208  HEFVEEKTKVAK----VSQGVEDGPDTKRAKLDSSETTMVKKKV--------------------------------------------- 247
           *********955....89999**********************9............................................. PP
   S: 268  skspfwvsfcsnaealqvpekvekdeevvkasaplylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepklddd 356
                   fc+++eal+v+++ ek ++++k++ + y+ll++l +f+++kgr+p++ ++e+d++ ++++ ++++     slgi+p   d 
   Q: 248  -------VFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVL----DSLGISP---DL 322
           .......8*****************************************************************....*******...55 PP
   S: 357  likeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfdaee 405
           l + +++++++++a+++avvgG++aqE++K++s++  p++nff+fd+++
   Q: 323  LPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMK 371
           5555666899************************************985 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MRRSTPGVLP AAVGGARVRR AVGLSGYGAE AGRAGAMVEK EEAGGGISEE EAAQYDRQIR 60
LWGLEAQKRL RASRVLLVGL KGLGAEIAKN LILAGVKGLT MLDHEQVTPE DPGAQFLIRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCTTTGA GTCTCGTGAG GTACTTTTGG TCCCGGGCTC CGCGGACGAG GTACTGCGCA 60
GGCGTGGGAG CGTCTGCGTA TGCGCAGAAG CACTCCGGGC GTGCTGCCGG CGGCGGTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF00899--ThiF

PRINTS

PR01849--UBIQUITINACT

Gene Ontology

GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000695	Aegilops tauschii	30.81	1.00e-39	157.00
IUUC-Aml-001477	Ailuropoda melanoleuca	96.35	0.00e+00	657.00
IUUC-Atr-002536	Amborella trichopoda	31.91	7.00e-42	164.00
IUUC-Apl-003982	Anas platyrhynchos	72.90	2.00e-104	371.00
IUUC-Aca-004868	Anolis carolinensis	80.30	1.00e-154	539.00
IUUC-Aly-005588	Arabidopsis lyrata	32.28	1.00e-44	173.00
IUUC-Ath-006677	Arabidopsis thaliana	33.33	2.00e-45	176.00
IUUC-Ago-007891	Ashbya gossypii	32.77	8.00e-45	174.00
IUUC-Acl-008197	Aspergillus clavatus	35.39	4.00e-53	201.00
IUUC-Afl-008520	Aspergillus flavus	33.33	3.00e-52	199.00
IUUC-Afu-009107	Aspergillus fumigatus	31.94	2.00e-45	176.00
IUUC-Ani-009143	Aspergillus nidulans	32.37	9.00e-43	167.00
IUUC-Ang-009804	Aspergillus niger	34.73	7.00e-54	204.00
IUUC-Aor-010190	Aspergillus oryzae	33.33	3.00e-52	199.00
IUUC-Ame-011043	Astyanax mexicanus	69.28	7.00e-128	449.00
IUUC-Bgr-012084	Blumeria graminis	32.09	2.00e-46	179.00
IUUC-Bta-012723	Bos taurus	96.34	0.00e+00	659.00
IUUC-Bci-013809	Botrytis cinerea	33.52	3.00e-50	192.00
IUUC-Bdi-014800	Brachypodium distachyon	33.33	6.00e-45	174.00
IUUC-Bol-015744	Brassica oleracea	30.99	9.00e-41	160.00
IUUC-Bra-016683	Brassica rapa	31.58	5.00e-42	164.00
IUUC-Cel-018434	Caenorhabditis elegans	30.92	6.00e-39	154.00
IUUC-Cja-019815	Callithrix jacchus	98.27	0.00e+00	704.00
IUUC-Cfa-020329	Canis familiaris	96.05	0.00e+00	658.00
IUUC-Cpo-022208	Cavia porcellus	94.22	0.00e+00	669.00
IUUC-Csa-023592	Chlorocebus sabaeus	98.56	5.00e-163	566.00
IUUC-Cho-024345	Choloepus hoffmanni	86.59	2.00e-127	447.00
IUUC-Cin-025351	Ciona intestinalis	44.94	4.00e-85	307.00
IUUC-Cgl-026491	Colletotrichum gloeosporioides	32.49	5.00e-43	168.00
IUUC-Cne-026970	Cryptococcus neoformans	28.88	2.00e-24	106.00
IUUC-Dre-028263	Danio rerio	69.36	3.00e-132	464.00
IUUC-Dno-030055	Dasypus novemcinctus	94.53	0.00e+00	652.00
IUUC-Dor-030864	Dipodomys ordii	92.01	8.00e-174	602.00
IUUC-Dse-031565	Dothistroma septosporum	33.91	2.00e-49	189.00
IUUC-Dme-032011	Drosophila melanogaster	39.42	5.00e-59	221.00
IUUC-Ete-032982	Echinops telfairi	83.14	2.00e-165	574.00
IUUC-Eca-034164	Equus caballus	95.54	0.00e+00	625.00
IUUC-Eeu-035135	Erinaceus europaeus	79.82	5.00e-101	360.00
IUUC-Fca-035564	Felis catus	96.96	0.00e+00	660.00
IUUC-Fox-037928	Fusarium oxysporum	32.77	3.00e-47	182.00
IUUC-Fso-038404	Fusarium solani	32.87	1.00e-46	181.00
IUUC-Gmo-038867	Gadus morhua	67.54	3.00e-127	447.00
IUUC-Ggr-040068	Gaeumannomyces graminis	35.16	4.00e-51	195.00
IUUC-Gga-041197	Gallus gallus	74.47	4.00e-128	450.00
IUUC-Gac-042609	Gasterosteus aculeatus	67.34	2.00e-129	454.00
IUUC-Gma-044135	Glycine max	30.55	2.00e-44	172.00
IUUC-Ggo-044600	Gorilla gorilla	100.00	0.00e+00	680.00
IUUC-Hsa-046731	Homo sapiens	100.00	0.00e+00	680.00
IUUC-Itr-049038	Ictidomys tridecemlineatus	97.87	0.00e+00	669.00
IUUC-Kpa-049371	Komagataella pastoris	28.81	8.00e-34	137.00
IUUC-Lch-050045	Latimeria chalumnae	77.68	1.00e-155	542.00
IUUC-Lpe-051103	Leersia perrieri	30.97	2.00e-42	166.00
IUUC-Loc-051749	Lepisosteus oculatus	64.97	2.00e-125	441.00
IUUC-Lma-053150	Leptosphaeria maculans	36.24	1.00e-50	193.00
IUUC-Laf-053875	Loxodonta africana	95.74	0.00e+00	658.00
IUUC-Mcc-055107	Macaca mulatta	98.68	6.00e-180	622.00
IUUC-Meu-056076	Macropus eugenii	64.16	4.00e-123	434.00
IUUC-Mor-057029	Magnaporthe oryzae	35.26	2.00e-48	186.00
IUUC-Mtr-058633	Medicago truncatula	32.65	5.00e-43	168.00
IUUC-Mvi-060367	Microbotryum violaceum	33.52	4.00e-53	201.00
IUUC-Mmr-061294	Microcebus murinus	95.05	6.00e-174	602.00
IUUC-Mdo-062827	Monodelphis domestica	87.32	0.00e+00	634.00
IUUC-Mmu-063568	Mus musculus	93.01	3.00e-177	613.00
IUUC-Mac-064495	Musa acuminata	29.74	3.00e-41	162.00
IUUC-Mpu-065826	Mustela putorius furo	95.44	0.00e+00	654.00
IUUC-Mlu-067751	Myotis lucifugus	94.27	1.00e-178	618.00
IUUC-Nfi-068597	Neosartorya fischeri	35.13	3.00e-55	208.00
IUUC-Ncr-068768	Neurospora crassa	32.72	3.00e-46	179.00
IUUC-Nle-069882	Nomascus leucogenys	98.11	5.00e-102	363.00
IUUC-Opr-071077	Ochotona princeps	66.87	4.00e-122	431.00
IUUC-Ont-072576	Oreochromis niloticus	69.65	1.00e-123	436.00
IUUC-Oan-073560	Ornithorhynchus anatinus	84.82	4.00e-158	550.00
IUUC-Ocu-074732	Oryctolagus cuniculus	87.43	9.00e-171	592.00
IUUC-Oba-075956	Oryza barthii	31.85	3.00e-44	172.00
IUUC-Obr-076004	Oryza brachyantha	31.25	1.00e-41	163.00
IUUC-Ogu-078335	Oryza glumaepatula	31.85	5.00e-44	171.00
IUUC-Oin-079177	Oryza indica	31.85	8.00e-45	174.00
IUUC-Olo-080537	Oryza longistaminata	29.64	1.00e-36	147.00
IUUC-Ome-081880	Oryza meridionalis	31.85	8.00e-45	174.00
IUUC-Oni-082688	Oryza nivara	32.14	2.00e-45	176.00
IUUC-Opu-083231	Oryza punctata	32.76	3.00e-48	185.00
IUUC-Oru-084759	Oryza rufipogon	31.85	8.00e-45	174.00
IUUC-Osa-085601	Oryza sativa	31.55	2.00e-44	172.00
IUUC-Ola-086496	Oryzias latipes	69.16	8.00e-124	436.00
IUUC-Oga-089005	Otolemur garnettii	88.82	2.00e-175	607.00
IUUC-Oar-089611	Ovis aries	96.34	0.00e+00	658.00
IUUC-Ptr-091337	Pan troglodytes	100.00	0.00e+00	680.00
IUUC-Pan-092401	Papio anubis	92.40	0.00e+00	627.00
IUUC-Pma-094210	Petromyzon marinus	59.65	2.00e-120	424.00
IUUC-Pno-094975	Phaeosphaeria nodorum	34.44	2.00e-49	189.00
IUUC-Ppa-095925	Physcomitrella patens	35.65	2.00e-53	202.00
IUUC-Pfo-096890	Poecilia formosa	68.21	8.00e-129	452.00
IUUC-Pop-099145	Populus trichocarpa	33.14	3.00e-46	178.00
IUUC-Pca-100899	Procavia capensis	78.42	4.00e-140	490.00
IUUC-Ppe-101274	Prunus persica	30.22	7.00e-32	130.00
IUUC-Pva-102625	Pteropus vampyrus	93.92	0.00e+00	646.00
IUUC-Pgr-103426	Puccinia graminis	36.34	9.00e-56	210.00
IUUC-Pte-104082	Pyrenophora teres	35.44	9.00e-49	187.00
IUUC-Pyt-104818	Pyrenophora triticirepentis	34.96	5.00e-48	184.00
IUUC-Rno-106129	Rattus norvegicus	92.15	0.00e+00	645.00
IUUC-Sce-106370	Saccharomyces cerevisiae	34.02	6.00e-44	171.00
IUUC-Sha-107120	Sarcophilus harrisii	85.40	7.00e-158	549.00
IUUC-Sja-107996	Schizosaccharomyces japonicus	31.29	4.00e-39	154.00
IUUC-Spo-108321	Schizosaccharomyces pombe	29.22	1.00e-31	129.00
IUUC-Ssl-108608	Sclerotinia sclerotiorum	34.21	4.00e-49	188.00
IUUC-Smo-109539	Selaginella moellendorffii	29.91	7.00e-35	140.00
IUUC-Sit-110166	Setaria italica	33.05	3.00e-47	182.00
IUUC-Sly-111116	Solanum lycopersicum	31.83	2.00e-42	166.00
IUUC-Stu-112397	Solanum tuberosum	32.13	3.00e-42	165.00
IUUC-Sar-113506	Sorex araneus	84.10	2.00e-172	597.00
IUUC-Sbi-114548	Sorghum bicolor	33.72	2.00e-47	182.00
IUUC-Ssc-115891	Sus scrofa	96.66	0.00e+00	662.00
IUUC-Tru-118469	Takifugu rubripes	64.74	6.00e-123	433.00
IUUC-Tsy-119304	Tarsius syrichta	86.58	7.00e-158	549.00
IUUC-Tni-119803	Tetraodon nigroviridis	59.54	3.00e-118	418.00
IUUC-Tca-121747	Theobroma cacao	31.17	3.00e-46	178.00
IUUC-Tre-122060	Trichoderma reesei	33.33	2.00e-45	176.00
IUUC-Tvi-122324	Trichoderma virens	33.62	9.00e-47	180.00
IUUC-Tae-123512	Triticum aestivum	32.14	1.00e-44	173.00
IUUC-Tur-126224	Triticum urartu	32.46	2.00e-43	169.00
IUUC-Tme-126939	Tuber melanosporum	35.21	2.00e-52	199.00
IUUC-Tbe-127982	Tupaia belangeri	85.71	5.00e-169	586.00
IUUC-Ttr-128758	Tursiops truncatus	96.05	0.00e+00	661.00
IUUC-Vda-129664	Verticillium dahliae	32.30	7.00e-43	167.00
IUUC-Vpa-130778	Vicugna pacos	80.60	2.00e-136	478.00
IUUC-Vvi-131399	Vitis vinifera	32.36	7.00e-45	174.00
IUUC-Xtr-131919	Xenopus tropicalis	73.49	2.00e-144	504.00
IUUC-Xma-133482	Xiphophorus maculatus	69.16	2.00e-126	444.00
IUUC-Yli-134596	Yarrowia lipolytica	28.92	2.00e-34	139.00
IUUC-Zma-135688	Zea mays	33.14	4.00e-47	181.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence