iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040256

Ensembl Protein ID

ENSGALP00000020664.4

UniProt Accession

E1BRG4; E1BRG4_CHICK

Genbank Protein ID

ENSGALP00000020664

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000074

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000012683.4	ENSGALT00000020693.4	ENSGALP00000020664.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	6.40e-49	167.2	30	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c+++  l+e+ei++ lv  ++++ +++l++e++v+ d+++
   Q: 30   CKLCLCEYSLDKMTTLQECRCIFCTSCLKQYMQLAIQEGCGSPITCPDMLCVNHgtLQEAEIAC-LVPVDQFQLFKRLKFEREVHLDPQR 118
           ****************************************************988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcpa+dC++v+++ +++    + vec++c++ fC++Cke+wH+++ C e +  +++++     +   + +ea +k+Cp C++yie+neg
   Q: 119  TWCPAADCQTVCCIGPNEsgVPVPVECPACHMMFCSSCKEAWHPQRLCPENQALVTTEQ----GSLIGTETEAPIKQCPVCRIYIERNEG 204
           *************9988744566777***********************9887766655....78889999******************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 205  CAQMMCKNCKHTFCWYC 221
           ***************** PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MGSAGKPSPD TMTADKSEAG DLALEPLLTC KLCLCEYSLD KMTTLQECRC IFCTSCLKQY 60
MQLAIQEGCG SPITCPDMLC VNHGTLQEAE IACLVPVDQF QLFKRLKFER EVHLDPQRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGAGGGGA CAACTGATGA GAGAATGGGC TCCGCGGGGA AGCCTAGCCC TGATACCATG 60
ACAGCTGACA AGTCAGAAGC TGGAGACTTA GCTCTGGAGC CCCTGCTCAC TTGCAAGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	79.72	2.00e-133	468.00
IUUC-Apl-004112	Anas platyrhynchos	93.95	4.00e-146	510.00
IUUC-Aca-004533	Anolis carolinensis	78.29	1.00e-129	455.00
IUUC-Bta-012641	Bos taurus	80.14	2.00e-132	464.00
IUUC-Cja-019626	Callithrix jacchus	70.71	6.00e-113	399.00
IUUC-Cfa-020702	Canis familiaris	78.29	1.00e-130	458.00
IUUC-Cpo-022147	Cavia porcellus	79.72	1.00e-130	458.00
IUUC-Csa-023473	Chlorocebus sabaeus	80.07	6.00e-133	466.00
IUUC-Cho-024298	Choloepus hoffmanni	77.04	8.00e-119	419.00
IUUC-Dre-028099	Danio rerio	62.20	2.00e-82	298.00
IUUC-Dno-029122	Dasypus novemcinctus	74.47	2.00e-121	428.00
IUUC-Dor-030669	Dipodomys ordii	81.99	4.00e-103	367.00
IUUC-Ete-033141	Echinops telfairi	66.90	7.00e-95	340.00
IUUC-Eca-034360	Equus caballus	81.14	4.00e-135	473.00
IUUC-Eeu-034538	Erinaceus europaeus	63.87	1.00e-64	238.00
IUUC-Fca-036055	Felis catus	77.94	3.00e-129	454.00
IUUC-Fal-037339	Ficedula albicollis	87.81	4.00e-145	506.00
IUUC-Gmo-038780	Gadus morhua	56.80	4.00e-80	291.00
IUUC-Gac-042127	Gasterosteus aculeatus	57.35	3.00e-81	294.00
IUUC-Ggo-044867	Gorilla gorilla	80.07	1.00e-132	465.00
IUUC-Hsa-046928	Homo sapiens	79.72	4.00e-132	463.00
IUUC-Hvu-047484	Hordeum vulgare	31.71	4.00e-20	92.40
IUUC-Itr-048250	Ictidomys tridecemlineatus	80.70	6.00e-81	292.00
IUUC-Lch-050168	Latimeria chalumnae	73.14	1.00e-122	432.00
IUUC-Lpe-051649	Leersia perrieri	29.13	2.00e-18	87.80
IUUC-Loc-052150	Lepisosteus oculatus	58.72	2.00e-87	315.00
IUUC-Laf-053967	Loxodonta africana	80.07	4.00e-134	470.00
IUUC-Mcc-055898	Macaca mulatta	80.07	6.00e-133	466.00
IUUC-Meu-056628	Macropus eugenii	92.31	3.00e-42	164.00
IUUC-Mtr-057989	Medicago truncatula	27.23	8.00e-18	84.00
IUUC-Mga-059820	Meleagris gallopavo	98.68	7.00e-164	569.00
IUUC-Mmr-060680	Microcebus murinus	80.07	1.00e-132	465.00
IUUC-Mdo-062839	Monodelphis domestica	77.30	5.00e-130	456.00
IUUC-Mmu-063339	Mus musculus	78.15	7.00e-117	412.00
IUUC-Mac-065414	Musa acuminata	29.54	5.00e-21	94.70
IUUC-Mpu-065973	Mustela putorius furo	77.58	3.00e-130	457.00
IUUC-Mlu-067112	Myotis lucifugus	78.65	2.00e-131	461.00
IUUC-Nle-069795	Nomascus leucogenys	79.72	2.00e-132	464.00
IUUC-Opr-070390	Ochotona princeps	77.43	1.00e-117	415.00
IUUC-Ont-072329	Oreochromis niloticus	61.13	1.00e-86	312.00
IUUC-Oan-072980	Ornithorhynchus anatinus	78.26	8.00e-120	422.00
IUUC-Ocu-073845	Oryctolagus cuniculus	80.20	1.00e-132	465.00
IUUC-Ola-086872	Oryzias latipes	60.39	2.00e-80	291.00
IUUC-Oga-088954	Otolemur garnettii	79.36	1.00e-132	465.00
IUUC-Oar-089879	Ovis aries	80.14	3.00e-132	464.00
IUUC-Ptr-090685	Pan troglodytes	79.72	4.00e-132	463.00
IUUC-Pan-092086	Papio anubis	80.43	3.00e-133	467.00
IUUC-Psi-093481	Pelodiscus sinensis	83.17	3.00e-129	454.00
IUUC-Pfo-096065	Poecilia formosa	62.95	8.00e-84	303.00
IUUC-Pab-098031	Pongo abelii	79.72	5.00e-132	463.00
IUUC-Pop-099816	Populus trichocarpa	29.58	2.00e-19	90.10
IUUC-Pca-100936	Procavia capensis	80.07	1.00e-133	468.00
IUUC-Pva-102864	Pteropus vampyrus	67.97	6.00e-108	383.00
IUUC-Rno-105503	Rattus norvegicus	78.52	1.00e-117	415.00
IUUC-Sha-107425	Sarcophilus harrisii	79.28	2.00e-132	464.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	26.87	6.00e-09	55.80
IUUC-Stu-112736	Solanum tuberosum	28.45	4.00e-20	91.30
IUUC-Ssc-115458	Sus scrofa	80.00	2.00e-132	464.00
IUUC-Tgu-117226	Taeniopygia guttata	88.53	1.00e-145	508.00
IUUC-Tru-118362	Takifugu rubripes	58.84	1.00e-84	306.00
IUUC-Tsy-119255	Tarsius syrichta	80.07	1.00e-132	465.00
IUUC-Tni-120140	Tetraodon nigroviridis	60.08	4.00e-80	290.00
IUUC-Tae-124420	Triticum aestivum	32.50	9.00e-21	94.70
IUUC-Tbe-127306	Tupaia belangeri	80.07	6.00e-133	466.00
IUUC-Ttr-128923	Tursiops truncatus	79.79	5.00e-131	460.00
IUUC-Vpa-130148	Vicugna pacos	80.78	5.00e-134	469.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence