iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036137

Ensembl Protein ID

ENSFCAP00000018565.1

UniProt Accession

M3WW28; M3WW28_FELCA

Genbank Protein ID

ENSFCAP00000018565

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02063106

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000024468.1	ENSFCAT00000030679.1	ENSFCAP00000018565.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-81	274.0	445	946

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRVFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++  ++ + ++++ ++         ++  + + +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlqvQSSHKPPSSLGCNETSFQEVaskaavltESPCTSEGEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 611
           ******************6577755555555556666666666788888877778888889**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ +++                                                                       
   Q: 612  AFTDLSLAFCPSSSIENLsfqdaasspntqdgdlmqasipseepgvyspataafvcdsavnermslsppdefcctdntsvphesskilv 700
           *********9998765558********************************************************************** PP
   S: 186  ..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
                         s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L+
   Q: 701  nkdvpqrpgggstpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLE 789
           *************************************************************************************9999 PP
   S: 261  lspfcts...........................peekqke........kkkYeLiavvvHsG.slssGHYvayvkn............ 301
           l    t+                           +     e         + Y L++vvvHsG s++sGHY++y++n            
   Q: 790  LPVKRTTfsslseswsidvdftdisenlakklksS-----EteeaccsrLVPYLLSSVVVHSGiSSESGHYYSYARNitgtessyqmch 873
           98555555566667777777777666666555440.....1555666669*************************************** PP
   S: 302  ................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                            +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 874  qsetlalassqshllgrnspsavieqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 946
           ********9999999999999999988865544555*******************999************986 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLQ QGYHSLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGGAGG GGCGGGCCGT TTCCGGAGGG TCTTAGTCCT TCACTTCCTG TTTGTGGGAC 60
CTTCTGAATC CGGGTCAAGT GTGTTAGCTT CTTCTCTTCT CCGGAGCTGA CCCGGCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fca:101088743

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	95.70	0.00e+00	1895.00
IUUC-Apl-003435	Anas platyrhynchos	75.96	0.00e+00	1269.00
IUUC-Aca-004556	Anolis carolinensis	70.87	0.00e+00	1312.00
IUUC-Ame-010616	Astyanax mexicanus	61.96	0.00e+00	1229.00
IUUC-Bta-013544	Bos taurus	93.28	0.00e+00	1858.00
IUUC-Cja-018745	Callithrix jacchus	91.59	0.00e+00	1852.00
IUUC-Cfa-020434	Canis familiaris	91.63	0.00e+00	1825.00
IUUC-Cpo-021666	Cavia porcellus	91.36	0.00e+00	1775.00
IUUC-Csa-023965	Chlorocebus sabaeus	93.86	0.00e+00	1958.00
IUUC-Cho-024809	Choloepus hoffmanni	84.23	0.00e+00	1280.00
IUUC-Cin-025604	Ciona intestinalis	30.05	3.00e-41	162.00
IUUC-Csv-026333	Ciona savignyi	41.28	2.00e-31	128.00
IUUC-Dre-028338	Danio rerio	62.48	0.00e+00	1239.00
IUUC-Dno-029372	Dasypus novemcinctus	91.94	0.00e+00	1850.00
IUUC-Dor-030752	Dipodomys ordii	88.95	0.00e+00	1250.00
IUUC-Dme-031871	Drosophila melanogaster	30.10	1.00e-46	181.00
IUUC-Ete-032588	Echinops telfairi	79.74	0.00e+00	1144.00
IUUC-Eca-034416	Equus caballus	95.20	0.00e+00	1955.00
IUUC-Eeu-035132	Erinaceus europaeus	74.15	0.00e+00	1426.00
IUUC-Fal-037297	Ficedula albicollis	75.02	0.00e+00	1449.00
IUUC-Gmo-038727	Gadus morhua	66.08	0.00e+00	1014.00
IUUC-Gga-041091	Gallus gallus	73.78	0.00e+00	1405.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.41	0.00e+00	1128.00
IUUC-Ggo-045376	Gorilla gorilla	88.53	0.00e+00	1770.00
IUUC-Hsa-046444	Homo sapiens	93.57	0.00e+00	1915.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	92.61	0.00e+00	1888.00
IUUC-Lch-050500	Latimeria chalumnae	72.18	0.00e+00	1425.00
IUUC-Loc-052625	Lepisosteus oculatus	65.39	0.00e+00	1308.00
IUUC-Laf-053689	Loxodonta africana	92.97	0.00e+00	1882.00
IUUC-Mcc-055286	Macaca mulatta	93.86	0.00e+00	1900.00
IUUC-Mga-059905	Meleagris gallopavo	74.26	0.00e+00	1238.00
IUUC-Mmr-061397	Microcebus murinus	94.34	0.00e+00	1896.00
IUUC-Mdo-062833	Monodelphis domestica	86.22	0.00e+00	1797.00
IUUC-Mmu-063157	Mus musculus	90.02	0.00e+00	1824.00
IUUC-Mpu-066434	Mustela putorius furo	96.07	0.00e+00	1950.00
IUUC-Mlu-068178	Myotis lucifugus	92.73	0.00e+00	1817.00
IUUC-Nle-070153	Nomascus leucogenys	92.90	0.00e+00	1827.00
IUUC-Ont-072330	Oreochromis niloticus	63.90	0.00e+00	1255.00
IUUC-Oan-072709	Ornithorhynchus anatinus	81.10	0.00e+00	1305.00
IUUC-Ocu-074832	Oryctolagus cuniculus	93.67	0.00e+00	1874.00
IUUC-Ola-087003	Oryzias latipes	56.31	1.00e-50	192.00
IUUC-Oga-088517	Otolemur garnettii	88.73	0.00e+00	1774.00
IUUC-Oar-089472	Ovis aries	89.53	0.00e+00	1785.00
IUUC-Ptr-090996	Pan troglodytes	93.19	0.00e+00	1908.00
IUUC-Pan-091837	Papio anubis	92.09	0.00e+00	1890.00
IUUC-Psi-093236	Pelodiscus sinensis	76.40	0.00e+00	1177.00
IUUC-Pma-094349	Petromyzon marinus	53.20	0.00e+00	996.00
IUUC-Pfo-097193	Poecilia formosa	62.74	0.00e+00	1154.00
IUUC-Pab-098710	Pongo abelii	93.57	0.00e+00	1916.00
IUUC-Pca-100794	Procavia capensis	81.78	0.00e+00	1634.00
IUUC-Pva-102722	Pteropus vampyrus	93.29	0.00e+00	1889.00
IUUC-Rno-105743	Rattus norvegicus	89.53	0.00e+00	1792.00
IUUC-Sha-106563	Sarcophilus harrisii	84.45	0.00e+00	1442.00
IUUC-Sar-113533	Sorex araneus	78.10	0.00e+00	1576.00
IUUC-Ssc-116259	Sus scrofa	83.83	0.00e+00	1571.00
IUUC-Tgu-117475	Taeniopygia guttata	74.32	0.00e+00	1299.00
IUUC-Tru-118623	Takifugu rubripes	63.25	0.00e+00	1154.00
IUUC-Tsy-119250	Tarsius syrichta	91.89	0.00e+00	1488.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.38	0.00e+00	1067.00
IUUC-Tbe-127936	Tupaia belangeri	81.56	0.00e+00	1572.00
IUUC-Ttr-128483	Tursiops truncatus	79.56	0.00e+00	1407.00
IUUC-Vpa-130303	Vicugna pacos	98.13	0.00e+00	1078.00
IUUC-Xtr-132773	Xenopus tropicalis	72.92	0.00e+00	1422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence