iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074832

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02045710

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011524.3	ENSOCUT00000011525.3	ENSOCUP00000009910.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.20e-81	272.8	445	949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    ++ ++ +e+ + ++++l++         +   +   +k+li+++F+g+l+++i+cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlrvQSLHKSSESLGCTETSLQEVvskaaaltETPCTSDGEKTLIEKMFGGKLQTHIRCLNCRSTSQKVE 611
           ******************6677766666666667777777777788887777777777888**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ +++                                                                       
   Q: 612  AFTDLSLAFCPSSSVENLsfqdlasspdvqdngllrtivsghseepvvynpataafvhdsvvnertihsppdefhctentsvpnesnki 700
           *********9999766669********************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+++n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl 
   Q: 701  lvnkdvpqkpggettpSVTDLLNYFLAPEILTDDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLV 789
           ***************************************************************************************** PP
   S: 259  Ldlspfcts.....peekqke...............................kkkYeLiavvvHsG.slssGHYvayvkn......... 301
           L+l    t+     +     e                                + Y L++vvvHsG s++sGHY++y++n         
   Q: 790  LELPVKRTTsfsslS-----EswsvdvdftdisenlakklkpsgtedaccpkLVPYLLSSVVVHSGvSSESGHYYSYARNitgtestyq 873
           999965555344440.....345555555555566666666666777777779************************************ PP
   S: 302  ...................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                               +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 874  mchqsetlalassqshllgrespsaifeqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 949
           ***********9999999999999999988865544555*******************999************986 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPVKRV IVRKVVESAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLQ QGYHSLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCTTCGCC TCTCTGCACT CTGACTGCTC CCGGCACCCT CCGTGACAGC GCCTACTGAC 60
TCAGCCCGGG ACCAGTGTCT TTTCTCGGCC TGCTGGAGCC TGGACGCCCG TACCTGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ocu:100347074

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	93.21	0.00e+00	1828.00
IUUC-Apl-003435	Anas platyrhynchos	76.01	0.00e+00	1262.00
IUUC-Aca-004556	Anolis carolinensis	71.04	0.00e+00	1252.00
IUUC-Ame-010616	Astyanax mexicanus	62.49	0.00e+00	1212.00
IUUC-Bta-013544	Bos taurus	92.99	0.00e+00	1800.00
IUUC-Cja-018745	Callithrix jacchus	92.45	0.00e+00	1826.00
IUUC-Cfa-020434	Canis familiaris	89.64	0.00e+00	1763.00
IUUC-Cpo-021666	Cavia porcellus	92.03	0.00e+00	1758.00
IUUC-Csa-023965	Chlorocebus sabaeus	94.15	0.00e+00	1901.00
IUUC-Cho-024809	Choloepus hoffmanni	84.47	0.00e+00	1248.00
IUUC-Cin-025604	Ciona intestinalis	37.39	2.00e-41	162.00
IUUC-Csv-026333	Ciona savignyi	44.00	3.00e-32	131.00
IUUC-Dre-028338	Danio rerio	62.82	0.00e+00	1212.00
IUUC-Dno-029372	Dasypus novemcinctus	92.03	0.00e+00	1808.00
IUUC-Dor-030752	Dipodomys ordii	89.21	0.00e+00	1232.00
IUUC-Dme-031871	Drosophila melanogaster	30.80	1.00e-46	181.00
IUUC-Ete-032588	Echinops telfairi	80.39	0.00e+00	1113.00
IUUC-Eca-034416	Equus caballus	94.34	0.00e+00	1891.00
IUUC-Eeu-035132	Erinaceus europaeus	73.60	0.00e+00	1367.00
IUUC-Fca-036137	Felis catus	93.67	0.00e+00	1847.00
IUUC-Fal-037297	Ficedula albicollis	75.74	0.00e+00	1433.00
IUUC-Gmo-038727	Gadus morhua	65.91	0.00e+00	1016.00
IUUC-Gga-041091	Gallus gallus	73.73	0.00e+00	1381.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.29	0.00e+00	1130.00
IUUC-Ggo-045376	Gorilla gorilla	89.29	0.00e+00	1728.00
IUUC-Hsa-046444	Homo sapiens	94.24	0.00e+00	1871.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	93.57	0.00e+00	1858.00
IUUC-Lch-050500	Latimeria chalumnae	71.61	0.00e+00	1402.00
IUUC-Loc-052625	Lepisosteus oculatus	65.67	0.00e+00	1272.00
IUUC-Laf-053689	Loxodonta africana	93.46	0.00e+00	1837.00
IUUC-Mcc-055286	Macaca mulatta	94.24	0.00e+00	1863.00
IUUC-Mga-059905	Meleagris gallopavo	74.05	0.00e+00	1238.00
IUUC-Mmr-061397	Microcebus murinus	95.39	0.00e+00	1890.00
IUUC-Mdo-062833	Monodelphis domestica	86.60	0.00e+00	1755.00
IUUC-Mmu-063157	Mus musculus	90.50	0.00e+00	1801.00
IUUC-Mpu-066434	Mustela putorius furo	93.86	0.00e+00	1856.00
IUUC-Mlu-068178	Myotis lucifugus	92.45	0.00e+00	1787.00
IUUC-Nle-070153	Nomascus leucogenys	94.05	0.00e+00	1830.00
IUUC-Ont-072330	Oreochromis niloticus	62.80	0.00e+00	1205.00
IUUC-Oan-072709	Ornithorhynchus anatinus	80.91	0.00e+00	1272.00
IUUC-Ola-087003	Oryzias latipes	55.56	3.00e-45	174.00
IUUC-Oga-088517	Otolemur garnettii	89.78	0.00e+00	1772.00
IUUC-Oar-089472	Ovis aries	89.35	0.00e+00	1731.00
IUUC-Ptr-090996	Pan troglodytes	93.86	0.00e+00	1863.00
IUUC-Pan-091837	Papio anubis	92.18	0.00e+00	1847.00
IUUC-Psi-093236	Pelodiscus sinensis	76.23	0.00e+00	1161.00
IUUC-Pma-094349	Petromyzon marinus	52.80	0.00e+00	942.00
IUUC-Pfo-097193	Poecilia formosa	63.09	0.00e+00	1147.00
IUUC-Pab-098710	Pongo abelii	94.05	0.00e+00	1882.00
IUUC-Pca-100794	Procavia capensis	82.36	0.00e+00	1592.00
IUUC-Pva-102722	Pteropus vampyrus	92.43	0.00e+00	1825.00
IUUC-Rno-105743	Rattus norvegicus	89.64	0.00e+00	1761.00
IUUC-Sha-106563	Sarcophilus harrisii	85.25	0.00e+00	1433.00
IUUC-Sar-113533	Sorex araneus	77.54	0.00e+00	1501.00
IUUC-Ssc-116259	Sus scrofa	83.44	0.00e+00	1540.00
IUUC-Tgu-117475	Taeniopygia guttata	75.42	0.00e+00	1314.00
IUUC-Tru-118623	Takifugu rubripes	62.83	0.00e+00	1130.00
IUUC-Tsy-119250	Tarsius syrichta	92.38	0.00e+00	1451.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.36	0.00e+00	1061.00
IUUC-Tbe-127936	Tupaia belangeri	81.29	0.00e+00	1531.00
IUUC-Ttr-128483	Tursiops truncatus	80.61	0.00e+00	1410.00
IUUC-Vpa-130303	Vicugna pacos	96.25	0.00e+00	1059.00
IUUC-Xtr-132773	Xenopus tropicalis	72.92	0.00e+00	1380.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence