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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Ath-007186
UUCD1 version UUC-ArT-00637
Ensembl Protein ID AT3G01650.2
UniProt Accession Q9SS90; RGLG1_ARATH
Genbank Protein ID AAF01562.1; AEE73699.1; ANM63886.1; AT3G01650.1
Protein Name E3 ubiquitin-protein ligase RGLG1; RING domain ligase 1
Genbank Nucleotide ID AC009325; CP002686; CP002686; BX824117
Gene Name RGLG1; At3g01650; F4P13.19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G01650 AT3G01650.2 AT3G01650.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 20113438; 17586653
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description



     E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains. Regulates apical dominance by acting on the auxin transport proteins abundance (PubMed:17586653). Together with RGLG5, mediates the ubiquitination and subsequent proteasomal degradation of the target protein PP2CA. Functions as positive regulator of abscisic acid (ABA) signaling through ABA-dependent degradation of PP2CA, a major inhibitor of ABA signaling (PubMed:27577789). Acts as a negative regulator of drought stress response (PubMed:22095047).
E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains. Regulates apical dominance by acting on the auxin transport proteins abundance (PubMed:17586653). Together with RGLG5, mediates the ubiquitination and subsequent proteasomal degradation of the target protein PP2CA. Functions as positive regulator of abscisic acid (ABA) signaling through ABA-dependent degradation of PP2CA, a major inhibitor of ABA signaling (PubMed:27577789). Acts as a negative regulator of drought stress response (PubMed:22095047).
Protein Sequence
(Fasta)
MGGGNSKEES SSPSSSSWAS HQSYPQYGPD SYNYPPPPTY APAPSPAPAP APVPAPSPAS 60
SYGPQYSQEG YASQPNNPPP PTYAPAPSPA SSYGHQYSQE GYASAASQPN YPPPPSQSQV 120
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Protein Fasta Sequence



>IUUC-Ath-007186|E3,RING|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
CTTGGACTTG GACATGGTGG GCCAATAATA AACAAATCCA ACTAATCTTT TCCAGATTTC 60
ATGATTGAAA CGTAAAGTGA AAGATTAAAC AAGAGAAAAA AGGTTAGATA GCTTTCTGAA 120
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Nucleotide Fasta Sequence



>IUUC-Ath-007186|E3,RING|Arabidopsis thaliana
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Sequence Source Ensembl
Keyword

KW-0938--Abscisic acid signaling pathway
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0346--Stress response
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR010734--Copine
IPR002035--VWF_A
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF07002--Copine

SMART

SM00327--VWA

Gene Ontology

GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0080148--P:negative regulation of response to water deprivation

KEGG ath:AT3G01650
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002030 Ailuropoda melanoleuca 34.15 3.00e-28 119.00
IUUC-Aly-005819 Arabidopsis lyrata 93.28 0.00e+00 700.00
IUUC-Bol-015499 Brassica oleracea 88.95 0.00e+00 681.00
IUUC-Bra-018048 Brassica rapa 88.74 0.00e+00 682.00
IUUC-Cfa-020719 Canis familiaris 32.93 4.00e-27 115.00
IUUC-Cho-024698 Choloepus hoffmanni 37.39 4.00e-14 72.00
IUUC-Dno-029223 Dasypus novemcinctus 34.96 1.00e-28 120.00
IUUC-Fca-035987 Felis catus 33.74 4.00e-27 115.00
IUUC-Gma-043304 Glycine max 74.67 5.00e-164 570.00
IUUC-Lch-049873 Latimeria chalumnae 34.71 1.00e-27 117.00
IUUC-Laf-054417 Loxodonta africana 33.74 1.00e-27 117.00
IUUC-Mpu-065680 Mustela putorius furo 34.15 6.00e-28 118.00
IUUC-Ocu-074096 Oryctolagus cuniculus 32.92 8.00e-28 117.00
IUUC-Oga-088715 Otolemur garnettii 33.33 1.00e-25 112.00
IUUC-Pma-094267 Petromyzon marinus 34.94 3.00e-28 119.00
IUUC-Pfo-097293 Poecilia formosa 35.38 4.00e-27 115.00
IUUC-Smo-108807 Selaginella moellendorffii 61.99 5.00e-134 469.00
IUUC-Ssc-115580 Sus scrofa 33.33 8.00e-25 107.00
IUUC-Tru-118245 Takifugu rubripes 34.85 5.00e-28 118.00
Created Date 25-Jun-2017

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