iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001614

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01138377

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000010259.1	ENSAMET00000011255.1	ENSAMEP00000010792.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.20e-25	87.4	404	475
E3 adaptor/Cullin RING/DCX/DWD	8.30e-41	136.3	11	43
UBD/Beta-Prp	3.30e-55	187.5	7	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFLCPITRELMKDPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLPSVVLTPNRTLKMAISRWLETHQ 475
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l++++
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLSDFT 43
           9*********548***************98876 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  ++sllat s d+ti+++++++ +    + l+ h+ +v +++fsp+g +l+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SSSLLATCSLDKTIRLYSLSDFTElpHSPLKFHTYAVHCCCFSPSGHVLASCSTDGTTVLWNTQNGETLAVM 92
           566666655.55899..9********************666667889****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  lvsG +d t+ +w+ ++++ ++ + s++dg+    +++p+gnl+v+Gs  + + +Wd  t+++l+  +  
   Q: 93   EQPTgSPVRVCQFSPDSTCLVSGAADGTVVLWNAQSYKLYR-CGSVKDGSLVACAFSPNGNLFVTGSSCGDLTVWDD-TMRCLHSEKA- 178
           *766267*********************************9.*********************************97.99*****987. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+           ++l+s+++d ++k+w ++
   Q: 179  HDLGITCCDFSSQPvsdgerglqfFRLASCGQDCQIKIWVVS 220
           ***********99899***********************775 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLS DFTELPHSPL KFHTYAVHCC 60
CFSPSGHVLA SCSTDGTTVL WNTQNGETLA VMEQPTGSPV RVCQFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAC TAATTCACAC CTTAGCCGAT CATGGTGATG ATGTCAACTG CTGTGCGTTC 60
TCCTCTTCCC TCTTGGCTAC TTGCTCTTTG GACAAAACAA TTCGCCTGTA CTCCCTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

aml:100479363

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003529	Anas platyrhynchos	76.26	0.00e+00	774.00
IUUC-Aca-004257	Anolis carolinensis	70.43	0.00e+00	698.00
IUUC-Ame-011357	Astyanax mexicanus	52.72	8.00e-118	417.00
IUUC-Bta-013032	Bos taurus	89.31	0.00e+00	889.00
IUUC-Cja-018743	Callithrix jacchus	93.07	0.00e+00	928.00
IUUC-Cfa-021197	Canis familiaris	95.80	0.00e+00	954.00
IUUC-Cpo-022279	Cavia porcellus	89.92	0.00e+00	902.00
IUUC-Csa-023954	Chlorocebus sabaeus	93.49	0.00e+00	930.00
IUUC-Cho-025083	Choloepus hoffmanni	74.34	3.00e-159	554.00
IUUC-Cin-025786	Ciona intestinalis	34.68	2.00e-79	290.00
IUUC-Dre-028087	Danio rerio	57.00	2.00e-144	505.00
IUUC-Dno-028919	Dasypus novemcinctus	92.44	0.00e+00	924.00
IUUC-Dor-031112	Dipodomys ordii	88.66	0.00e+00	882.00
IUUC-Ete-032405	Echinops telfairi	88.63	0.00e+00	640.00
IUUC-Eca-033254	Equus caballus	91.39	0.00e+00	910.00
IUUC-Eeu-034545	Erinaceus europaeus	85.92	0.00e+00	836.00
IUUC-Fca-035482	Felis catus	96.64	0.00e+00	959.00
IUUC-Fal-036976	Ficedula albicollis	61.52	2.00e-165	575.00
IUUC-Gmo-039213	Gadus morhua	54.83	2.00e-138	485.00
IUUC-Gga-040561	Gallus gallus	75.26	0.00e+00	756.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.98	3.00e-142	498.00
IUUC-Ggo-045503	Gorilla gorilla	93.49	0.00e+00	934.00
IUUC-Hsa-045910	Homo sapiens	93.49	0.00e+00	934.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	90.19	0.00e+00	714.00
IUUC-Loc-052307	Lepisosteus oculatus	59.33	1.00e-167	582.00
IUUC-Laf-053587	Loxodonta africana	92.02	0.00e+00	919.00
IUUC-Mcc-055679	Macaca mulatta	93.70	0.00e+00	934.00
IUUC-Meu-055962	Macropus eugenii	72.27	0.00e+00	664.00
IUUC-Mga-059652	Meleagris gallopavo	74.84	0.00e+00	759.00
IUUC-Mmr-060943	Microcebus murinus	90.17	0.00e+00	898.00
IUUC-Mdo-062592	Monodelphis domestica	83.51	0.00e+00	835.00
IUUC-Mmu-063577	Mus musculus	82.77	0.00e+00	826.00
IUUC-Mpu-066422	Mustela putorius furo	96.64	0.00e+00	954.00
IUUC-Mlu-067250	Myotis lucifugus	91.18	0.00e+00	905.00
IUUC-Nle-069517	Nomascus leucogenys	93.28	0.00e+00	932.00
IUUC-Opr-070776	Ochotona princeps	90.13	0.00e+00	888.00
IUUC-Ont-071821	Oreochromis niloticus	57.74	7.00e-152	530.00
IUUC-Oan-073706	Ornithorhynchus anatinus	83.16	0.00e+00	837.00
IUUC-Ocu-074766	Oryctolagus cuniculus	81.88	0.00e+00	797.00
IUUC-Ola-086531	Oryzias latipes	56.63	8.00e-147	513.00
IUUC-Oga-088388	Otolemur garnettii	88.87	0.00e+00	893.00
IUUC-Oar-089748	Ovis aries	89.31	0.00e+00	884.00
IUUC-Ptr-090616	Pan troglodytes	93.23	0.00e+00	925.00
IUUC-Pan-091769	Papio anubis	93.31	0.00e+00	669.00
IUUC-Psi-093334	Pelodiscus sinensis	78.78	0.00e+00	741.00
IUUC-Pma-094383	Petromyzon marinus	48.83	3.00e-133	468.00
IUUC-Pfo-096801	Poecilia formosa	56.37	8.00e-149	520.00
IUUC-Pab-098139	Pongo abelii	92.53	0.00e+00	751.00
IUUC-Pca-100523	Procavia capensis	75.63	0.00e+00	733.00
IUUC-Pva-102286	Pteropus vampyrus	90.55	0.00e+00	875.00
IUUC-Rno-104831	Rattus norvegicus	84.66	0.00e+00	845.00
IUUC-Sha-107499	Sarcophilus harrisii	84.24	0.00e+00	847.00
IUUC-Sar-113389	Sorex araneus	86.97	0.00e+00	842.00
IUUC-Tgu-116769	Taeniopygia guttata	73.74	0.00e+00	736.00
IUUC-Tru-118774	Takifugu rubripes	53.91	5.00e-140	491.00
IUUC-Tsy-119595	Tarsius syrichta	79.85	0.00e+00	645.00
IUUC-Tni-119850	Tetraodon nigroviridis	57.20	3.00e-148	518.00
IUUC-Tur-126683	Triticum urartu	53.03	4.00e-17	83.60
IUUC-Tbe-127938	Tupaia belangeri	81.97	1.00e-146	512.00
IUUC-Ttr-128193	Tursiops truncatus	91.51	0.00e+00	776.00
IUUC-Vpa-130275	Vicugna pacos	93.49	0.00e+00	928.00
IUUC-Xtr-131982	Xenopus tropicalis	61.47	9.00e-172	596.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence