iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013472

Ensembl Protein ID

ENSBTAP00000005923.5

UniProt Accession

F1N7Q0; F1N7Q0_BOVIN

Genbank Protein ID

DAA15665.1

Protein Name

BTB (POZ) domain containing 12

Genbank Nucleotide ID

DAAA02057328

Gene Name

SLX4; BTBD12; BOS_22567

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004509.5	ENSBTAT00000005923.5	ENSBTAP00000005923.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	8.20e-06	26.2	701	769
UBD/ZnF/UBZ	8.60e-09	35.6	304	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmele..es....ksklmveikdvqpevfrallkFlYtg 63
           +D++++++ ge+  ahk vL a+++ ++  +++e    e     + + +v ++dv++e+ +a+l++lY  
   Q: 701  SDIQFQIDsGEVLYAHKFVLYARCPLLMQHINSEAFlaEEdgdlR-HQRVLLRDVSAEAAQAFLHYLYAA 769
           699************************998866543223355557.99********************76 PP

UBD/ZnF/UBZ

   S: 2    lvCPvCqkm...vdqtdfeeHlDeCl 24
           ++C++Cqk    +++t++++H+++Cl
   Q: 304  FFCQICQKNlsaMNVTRRQQHVNRCL 329
           89***********************8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MYSLWEASTG QQTLSDVNFN KASSVNEAWP GSHLGSLSHL CTCPHIDPHF SEDQPESLQT 60
RQMMDESDDD FQELCASFFQ RVKKNGPKEV SKEKKTQKAS NGTHIRSKPK RTKPTASKSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCGCATGC GCAGGGGCTT GGGTCGCCGT TGAGAAGGTG CTGCGGCCGC GCCAGAGGTA 60
GGAGGAGTCG GGCTTTGGGG CCGGGAGTCT GCACCGGGGA GAGGAGGTCC TGCCGCCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:0036297--P:interstrand cross-link repair
GO:0000706--P:meiotic DNA double-strand break processing
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0000712--P:resolution of meiotic recombination intermediates
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	62.38	0.00e+00	1409.00
IUUC-Apl-003261	Anas platyrhynchos	34.43	0.00e+00	633.00
IUUC-Cja-019406	Callithrix jacchus	59.48	0.00e+00	1492.00
IUUC-Cfa-020129	Canis familiaris	61.83	0.00e+00	1528.00
IUUC-Cpo-021944	Cavia porcellus	51.79	0.00e+00	1184.00
IUUC-Csa-023941	Chlorocebus sabaeus	55.01	3.00e-175	609.00
IUUC-Cho-024847	Choloepus hoffmanni	64.09	1.00e-151	531.00
IUUC-Cin-025405	Ciona intestinalis	46.15	1.00e-08	54.30
IUUC-Dre-027764	Danio rerio	31.37	1.00e-74	276.00
IUUC-Dno-030083	Dasypus novemcinctus	55.10	0.00e+00	1266.00
IUUC-Dor-031129	Dipodomys ordii	47.85	3.00e-169	589.00
IUUC-Ete-032536	Echinops telfairi	42.67	4.00e-88	320.00
IUUC-Eca-033407	Equus caballus	64.21	0.00e+00	1359.00
IUUC-Eeu-034473	Erinaceus europaeus	46.85	3.00e-42	168.00
IUUC-Fca-035730	Felis catus	60.06	0.00e+00	1492.00
IUUC-Fal-036850	Ficedula albicollis	36.15	8.00e-132	465.00
IUUC-Gmo-038677	Gadus morhua	38.17	3.00e-25	110.00
IUUC-Gga-041088	Gallus gallus	40.21	1.00e-126	448.00
IUUC-Gac-041824	Gasterosteus aculeatus	44.87	1.00e-13	69.70
IUUC-Ggo-045642	Gorilla gorilla	59.87	0.00e+00	1249.00
IUUC-Hsa-047035	Homo sapiens	60.61	0.00e+00	1531.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	58.32	0.00e+00	1434.00
IUUC-Lch-050364	Latimeria chalumnae	39.49	4.00e-66	246.00
IUUC-Loc-052423	Lepisosteus oculatus	40.51	6.00e-41	163.00
IUUC-Laf-053910	Loxodonta africana	55.05	0.00e+00	1305.00
IUUC-Mcc-055883	Macaca mulatta	60.25	0.00e+00	1509.00
IUUC-Meu-056224	Macropus eugenii	45.99	2.00e-79	291.00
IUUC-Mga-059880	Meleagris gallopavo	42.84	7.00e-128	452.00
IUUC-Mmr-061715	Microcebus murinus	59.93	0.00e+00	1576.00
IUUC-Mdo-062426	Monodelphis domestica	40.68	0.00e+00	706.00
IUUC-Mmu-063947	Mus musculus	52.99	0.00e+00	1285.00
IUUC-Mpu-066184	Mustela putorius furo	60.34	0.00e+00	1535.00
IUUC-Mlu-067533	Myotis lucifugus	64.07	0.00e+00	1522.00
IUUC-Nle-069204	Nomascus leucogenys	58.46	0.00e+00	1490.00
IUUC-Opr-070377	Ochotona princeps	58.37	0.00e+00	802.00
IUUC-Ont-072551	Oreochromis niloticus	33.78	2.00e-65	244.00
IUUC-Oan-073350	Ornithorhynchus anatinus	47.54	1.00e-102	367.00
IUUC-Ocu-074915	Oryctolagus cuniculus	56.86	0.00e+00	828.00
IUUC-Ola-087360	Oryzias latipes	41.11	3.00e-32	131.00
IUUC-Oga-089106	Otolemur garnettii	53.78	0.00e+00	1122.00
IUUC-Oar-089289	Ovis aries	89.98	0.00e+00	1848.00
IUUC-Ptr-091469	Pan troglodytes	61.08	0.00e+00	1521.00
IUUC-Pan-091841	Papio anubis	58.05	0.00e+00	1097.00
IUUC-Psi-093842	Pelodiscus sinensis	45.92	2.00e-126	448.00
IUUC-Pma-094732	Petromyzon marinus	50.00	6.00e-08	50.40
IUUC-Pfo-097299	Poecilia formosa	38.60	3.00e-33	137.00
IUUC-Pab-098271	Pongo abelii	59.06	0.00e+00	1483.00
IUUC-Pca-100721	Procavia capensis	52.26	0.00e+00	834.00
IUUC-Pva-102276	Pteropus vampyrus	67.34	0.00e+00	1735.00
IUUC-Rno-105619	Rattus norvegicus	53.89	0.00e+00	1365.00
IUUC-Sha-106722	Sarcophilus harrisii	43.26	0.00e+00	723.00
IUUC-Sar-113673	Sorex araneus	54.23	1.00e-83	305.00
IUUC-Ssc-115383	Sus scrofa	64.59	0.00e+00	1524.00
IUUC-Tgu-117243	Taeniopygia guttata	46.53	3.00e-81	295.00
IUUC-Tru-118092	Takifugu rubripes	33.33	7.00e-26	110.00
IUUC-Tsy-119362	Tarsius syrichta	63.15	1.00e-157	551.00
IUUC-Tni-120380	Tetraodon nigroviridis	67.14	3.00e-21	95.50
IUUC-Tbe-127404	Tupaia belangeri	44.81	2.00e-147	517.00
IUUC-Ttr-128317	Tursiops truncatus	73.97	0.00e+00	1932.00
IUUC-Xtr-132533	Xenopus tropicalis	40.29	7.00e-88	319.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence