iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069800

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01127159

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000018125.1	ENSNLET00000023135.1	ENSNLEP00000022021.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-53	180.6	8	139
UBD/UBC-like/UBD_UBC	9.10e-82	272.0	8	142

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeee 90
           ++kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  +
   Q: 8    IHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--S 93
           689********************.9************************************************************9..* PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +Wspal++++vllsi+sll++pnp++pl  e+a+++k+++  y++++r
   Q: 94   QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDK--YNRIAR 139
           ************************************9987..677665 PP

UBD/UBC-like/UBD_UBC

   S: 2    ikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqws 90
           i+kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws
   Q: 8    IHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWS 96
           89*************************************************************************************** PP
   S: 91   aaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           +alt+skvlls+csll+d++pddplv+eiariyktd  ky+riarewt
   Q: 97   PALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTD--KYNRIAREWT 142
           **********************************96..7********8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

IVSNNPLIHK ELNDLARDPP AQCSAGPVGD DMFHWQATIM GPNDSPYQGG VFFLTIHFPT 60
DYPFKPPKVA FTTRIYHPNI NSNGSICLDI LRSQWSPALT ISKVLLSICS LLCDPNPDDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGTCTCTA ATAATCCTTT GTATTTCTGT GGTATCGGTT ATAATGTCTC TTTTTTATTT 60
CTTATTTTAT TTACTTGGGT CTTTTATTCT TAGTCTGGCT AATGGTTTGC CAATTTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	98.57	1.00e-78	284.00
IUUC-Apl-003199	Anas platyrhynchos	98.56	3.00e-78	283.00
IUUC-Dno-028952	Dasypus novemcinctus	98.57	7.00e-79	285.00
IUUC-Dor-030285	Dipodomys ordii	97.12	3.00e-77	280.00
IUUC-Ete-032295	Echinops telfairi	98.56	3.00e-78	283.00
IUUC-Eca-033293	Equus caballus	98.56	2.00e-78	284.00
IUUC-Eeu-034766	Erinaceus europaeus	95.71	1.00e-75	274.00
IUUC-Fal-036904	Ficedula albicollis	97.14	6.00e-78	282.00
IUUC-Ggo-045375	Gorilla gorilla	97.16	1.00e-78	284.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	98.57	5.00e-79	285.00
IUUC-Loc-052788	Lepisosteus oculatus	96.43	1.00e-77	281.00
IUUC-Laf-053580	Loxodonta africana	98.57	8.00e-79	285.00
IUUC-Mcc-054673	Macaca mulatta	98.56	2.00e-78	284.00
IUUC-Meu-056462	Macropus eugenii	95.68	3.00e-76	276.00
IUUC-Mga-059237	Meleagris gallopavo	95.10	8.00e-78	281.00
IUUC-Mmr-061474	Microcebus murinus	98.56	2.00e-78	283.00
IUUC-Mpu-066604	Mustela putorius furo	96.55	1.00e-78	285.00
IUUC-Opr-070191	Ochotona princeps	97.12	3.00e-77	280.00
IUUC-Pma-094405	Petromyzon marinus	94.07	5.00e-73	265.00
IUUC-Sar-113302	Sorex araneus	98.56	3.00e-78	283.00
IUUC-Ssc-116154	Sus scrofa	96.48	2.00e-78	283.00
IUUC-Tsy-119491	Tarsius syrichta	95.68	1.00e-73	269.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence