iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050332

Ensembl Protein ID

ENSLACP00000011612.1

UniProt Accession

H3APP1; H3APP1_LATCH

Genbank Protein ID

ENSLACP00000011612

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01138179

Gene Name

USP31

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010220.1	ENSLACT00000011701.1	ENSLACP00000011612.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-89	299.7	109	758

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp...................kepkgellkslqk 55
           GlkN+gNtC+mN+vLQcLsn++ ++e+l                  +         p                     +kge++++l +
   Q: 109  GLKNHGNTCFMNAVLQCLSNTELFAEYLALeqyrggggddsglagtE---------PeqqppksngvqqlfqnkkaAPEKGEVTEQLSN 188
           9***************************9966667665555555540.........1444444455555666666688889******** PP
   S: 56   lfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk..eknkpkeeeeeed.kselsdeaeekkkkknksl 141
           l+++lw+ + +    re++++++k a +++g++q+DaqEfl +lld+++e+l++  +    ++     +   e +  +e       +++
   Q: 189  LVRSLWTFEYTPQHSREFKNVVAKNALQYRGNSQHDAQEFLLWLLDRVHEDLNNvvK----YNGGPPLKpPVEDDATSEGPSLPVCNTF 273
           ****************************************************55321....22222222011222334556667777** PP
   S: 142  isdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............................................. 185
           +++lFq q++s+++c++c+++s++++pfl +slp+p  +++ ++                                             
   Q: 274  VEELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTR-PLyvtvvyqgkcshcmrigvavplsgtvarlreavsletkiptdqiv 361
           ************************************87755.34689****************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 362  ltemyydgfhrsfcdtedldtihesdcifafetpeifrpegilsqrgmlanlnqnnlkygteshrtttftqgvvkpvklelvssrptgs 450
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 451  dkivllvcnrvcsgqqgkrfghpfvlyldktvtwdalqkeileklhyilrpgvyiqvgpfslrvvgvvgltyllpqveqplshptvera 539
           ***************************************************************************************** PP
   S: 186  ..................................................slqdcLesftkeeelegenkyycekckkkqeaekklklk 224
                                                              l ++ + + +e +l  ++++ c++ck++q+ + kl+l+
   Q: 540  fkscgpggpphvkivvewdketkeylsssiredpppqvvtiyirfsrqwfYLFQVVAIYITEIKLAPDDAWRCPHCKQLQQGSIKLSLW 628
           ***************************************************************************************** PP
   S: 225  klPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssG 293
           +lP+vLi+hLkRf  ++e+++r k+++ ++fpl  Ld++p+++++++++ +                   ++ Y+L+av++H+G++++G
   Q: 629  TLPDVLIIHLKRF--RQEGDRRMKLQNMIKFPLVgLDMTPHVVKRSQSSWSlpshwspwrrpyglgrdpeDYLYDLYAVCNHHGTMHGG 715
           *************..99**************************977666559999999999999999999******************* PP
   S: 294  HYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           HY+a++kn  +g+W++fdDs V++v+e+ev++   +taY+lfY+rr
   Q: 716  HYTAFCKNsVDGQWYCFDDSDVQQVSEDEVCK---QTAYILFYQRR 758
           ********55777*******************...*********96 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

GEEGGGGGGG SGGGPGRSKK LFRRGSVRSV GSFMSRVIKT LSTLSHFGTE EAAAATAEEE 60
KDDGGFNSYK VSGGRSEPPQ QQQPPPPPHG GESEPPWPDG EARVPGLAGL KNHGNTCFMN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGAGGAGG GTGGTGGTGG TGGTGGCGGC AGTGGTGGGG GCCCAGGCAG GAGGAGAGCG 60
AGTGACCTGT GAGAAGGAAA AACAAACAAA TCACAGACAG CAGAGGTGGA GCAAGAAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001207	Ailuropoda melanoleuca	64.73	0.00e+00	1295.00
IUUC-Apl-003186	Anas platyrhynchos	66.87	0.00e+00	1221.00
IUUC-Aca-004949	Anolis carolinensis	71.14	0.00e+00	1147.00
IUUC-Ame-010968	Astyanax mexicanus	64.13	0.00e+00	1170.00
IUUC-Bta-013271	Bos taurus	73.03	0.00e+00	1191.00
IUUC-Cel-018710	Caenorhabditis elegans	23.38	4.00e-36	147.00
IUUC-Cja-019663	Callithrix jacchus	74.58	0.00e+00	1083.00
IUUC-Cfa-021258	Canis familiaris	65.83	0.00e+00	1313.00
IUUC-Csa-024188	Chlorocebus sabaeus	73.80	0.00e+00	1186.00
IUUC-Cho-024813	Choloepus hoffmanni	69.92	0.00e+00	922.00
IUUC-Csv-026086	Ciona savignyi	36.49	7.00e-122	431.00
IUUC-Dre-028066	Danio rerio	47.42	0.00e+00	702.00
IUUC-Dno-029964	Dasypus novemcinctus	74.52	0.00e+00	1109.00
IUUC-Dor-030448	Dipodomys ordii	58.37	0.00e+00	687.00
IUUC-Dme-032088	Drosophila melanogaster	41.53	8.00e-65	242.00
IUUC-Ete-032975	Echinops telfairi	55.33	0.00e+00	895.00
IUUC-Eca-034030	Equus caballus	65.67	0.00e+00	1244.00
IUUC-Eeu-034629	Erinaceus europaeus	73.60	5.00e-121	429.00
IUUC-Fca-035788	Felis catus	73.73	0.00e+00	1172.00
IUUC-Fal-036874	Ficedula albicollis	74.91	0.00e+00	1106.00
IUUC-Gmo-039479	Gadus morhua	58.04	0.00e+00	1226.00
IUUC-Gga-041092	Gallus gallus	63.39	0.00e+00	1302.00
IUUC-Gac-041778	Gasterosteus aculeatus	58.80	0.00e+00	1221.00
IUUC-Ggo-045171	Gorilla gorilla	43.48	0.00e+00	640.00
IUUC-Hsa-046805	Homo sapiens	73.50	0.00e+00	1229.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	67.44	0.00e+00	1189.00
IUUC-Loc-051953	Lepisosteus oculatus	66.39	0.00e+00	1415.00
IUUC-Laf-054033	Loxodonta africana	46.54	4.00e-178	618.00
IUUC-Mcc-055398	Macaca mulatta	64.06	0.00e+00	1275.00
IUUC-Meu-056822	Macropus eugenii	61.24	0.00e+00	1046.00
IUUC-Mga-060115	Meleagris gallopavo	64.59	0.00e+00	1191.00
IUUC-Mmr-061150	Microcebus murinus	64.92	0.00e+00	1239.00
IUUC-Mdo-062700	Monodelphis domestica	65.91	0.00e+00	1351.00
IUUC-Mmu-063512	Mus musculus	73.51	0.00e+00	1175.00
IUUC-Mpu-066059	Mustela putorius furo	64.36	0.00e+00	1127.00
IUUC-Mlu-067870	Myotis lucifugus	64.36	0.00e+00	1199.00
IUUC-Nle-069898	Nomascus leucogenys	73.40	0.00e+00	1227.00
IUUC-Opr-070338	Ochotona princeps	59.93	0.00e+00	642.00
IUUC-Ont-072354	Oreochromis niloticus	59.51	0.00e+00	1218.00
IUUC-Oan-073175	Ornithorhynchus anatinus	65.34	0.00e+00	1153.00
IUUC-Ocu-074014	Oryctolagus cuniculus	46.87	9.00e-150	523.00
IUUC-Ola-086745	Oryzias latipes	66.95	0.00e+00	1119.00
IUUC-Oga-089021	Otolemur garnettii	73.67	0.00e+00	1210.00
IUUC-Oar-090016	Ovis aries	73.01	0.00e+00	1196.00
IUUC-Ptr-090864	Pan troglodytes	73.50	0.00e+00	1229.00
IUUC-Pan-092370	Papio anubis	74.02	0.00e+00	1192.00
IUUC-Psi-093881	Pelodiscus sinensis	64.49	0.00e+00	1192.00
IUUC-Pfo-097171	Poecilia formosa	57.20	0.00e+00	1189.00
IUUC-Pab-098104	Pongo abelii	71.12	0.00e+00	1165.00
IUUC-Pca-100640	Procavia capensis	77.97	7.00e-106	379.00
IUUC-Pva-102287	Pteropus vampyrus	71.46	0.00e+00	1006.00
IUUC-Rno-106033	Rattus norvegicus	63.92	0.00e+00	1209.00
IUUC-Sha-107041	Sarcophilus harrisii	68.04	0.00e+00	1244.00
IUUC-Sar-113105	Sorex araneus	40.60	2.00e-119	423.00
IUUC-Ssc-115312	Sus scrofa	46.99	0.00e+00	634.00
IUUC-Tgu-116889	Taeniopygia guttata	66.00	0.00e+00	1211.00
IUUC-Tru-117929	Takifugu rubripes	64.28	0.00e+00	1136.00
IUUC-Tsy-118887	Tarsius syrichta	65.88	0.00e+00	1001.00
IUUC-Tni-120463	Tetraodon nigroviridis	68.98	0.00e+00	1122.00
IUUC-Tbe-127491	Tupaia belangeri	68.85	1.00e-78	288.00
IUUC-Ttr-128210	Tursiops truncatus	67.59	0.00e+00	1145.00
IUUC-Vpa-130222	Vicugna pacos	64.67	3.00e-172	598.00
IUUC-Xtr-132509	Xenopus tropicalis	60.31	0.00e+00	1166.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence