iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011157

Ensembl Protein ID

ENSAMXP00000018029.1

UniProt Accession

W5LDW7; W5LDW7_ASTMX

Genbank Protein ID

ENSAMXP00000018029

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

APWO01094013

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017512.1	ENSAMXT00000018029.1	ENSAMXP00000018029.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	3.50e-60	204.4	3	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakq 93
           +++wl+Le++P++++++++++g+   +q+ ++y+Ldpe l ++++pv+++lllF+++ek+es+r ++   ++++ +++++   ++f+ q
   Q: 3    GQRWLPLEANPDVMNQFLRQLGLVSTWQFGDVYGLDPELLTMVPRPVCAVLLLFPVTEKYESFRLEE--EAKIKAQGQEVSPDVYFMRQ 89
           479*************************************************************555..6789**************** PP
   S: 94   vigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfv 181
           +igN+C+t++l+++++n++ +l ++  + l+ ++ ++ + spe+ka  l++++ ++++h+s a+++++++p+ +       +k  +hf+
   Q: 90   TIGNACGTIGLIHAVANNQGHLeFEPNSPLKTFLVQSSKLSPEEKATFLEKDESIRVTHESSAQEGQTEAPSLD-------EKVDLHFI 171
           ***********************************************************************777.......8899**** PP
   S: 182  syvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaiva 243
           ++vn++g+l+eldg+kpfP+ +gk++e+  l+d+++v+++f+ r    + +e+rf+++a+++
   Q: 172  ALVNVGGHLHELDGRKPFPIVHGKTSEDSFLEDAAEVCKKFMAR----DPQELRFTVVALSK 229
           ********************************************....9*********9987 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MDGQRWLPLE ANPDVMNQFL RQLGLVSTWQ FGDVYGLDPE LLTMVPRPVC AVLLLFPVTE 60
KYESFRLEEE AKIKAQGQEV SPDVYFMRQT IGNACGTIGL IHAVANNQGH LEFEPNSPLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGGGC AGCGCTGGTT ACCACTGGAG GCGAATCCAG ACGTATGCAG CTTTGCTTTT 60
ACTTTCATTC AGTTTAATAG ACAGAAAACT AGCTGGATAT CGCTATTCAA TGAACCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007219--P:Notch signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	43.93	4.00e-52	197.00
IUUC-Aml-001344	Ailuropoda melanoleuca	73.04	1.00e-101	362.00
IUUC-Atr-002931	Amborella trichopoda	46.08	5.00e-48	183.00
IUUC-Apl-003949	Anas platyrhynchos	74.18	3.00e-87	314.00
IUUC-Aca-004924	Anolis carolinensis	74.46	8.00e-102	362.00
IUUC-Aly-005939	Arabidopsis lyrata	46.93	4.00e-55	207.00
IUUC-Ath-006827	Arabidopsis thaliana	48.02	1.00e-56	213.00
IUUC-Ago-007950	Ashbya gossypii	34.91	1.00e-27	116.00
IUUC-Acl-008305	Aspergillus clavatus	38.84	3.00e-36	145.00
IUUC-Afl-008611	Aspergillus flavus	41.45	2.00e-43	168.00
IUUC-Afu-008945	Aspergillus fumigatus	38.66	2.00e-39	155.00
IUUC-Ani-009339	Aspergillus nidulans	38.89	2.00e-40	158.00
IUUC-Ang-009691	Aspergillus niger	38.56	3.00e-40	158.00
IUUC-Aor-009961	Aspergillus oryzae	41.45	3.00e-43	168.00
IUUC-Ate-010316	Aspergillus terreus	40.34	2.00e-41	162.00
IUUC-Bgr-012125	Blumeria graminis	34.31	6.00e-35	140.00
IUUC-Bta-012673	Bos taurus	72.61	1.00e-101	362.00
IUUC-Bci-013734	Botrytis cinerea	37.18	4.00e-40	157.00
IUUC-Bdi-014330	Brachypodium distachyon	45.61	2.00e-55	208.00
IUUC-Bol-015214	Brassica oleracea	47.81	4.00e-57	214.00
IUUC-Bra-017491	Brassica rapa	47.81	7.00e-57	213.00
IUUC-Cel-018236	Caenorhabditis elegans	31.42	3.00e-22	98.60
IUUC-Cfa-020371	Canis familiaris	71.58	1.00e-79	288.00
IUUC-Cpo-022036	Cavia porcellus	72.17	2.00e-99	354.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	42.13	1.00e-35	142.00
IUUC-Csa-023854	Chlorocebus sabaeus	72.61	4.00e-100	357.00
IUUC-Cin-025545	Ciona intestinalis	52.65	6.00e-68	249.00
IUUC-Cgl-026659	Colletotrichum gloeosporioides	36.36	5.00e-30	124.00
IUUC-Cne-026914	Cryptococcus neoformans	34.75	3.00e-29	121.00
IUUC-Cme-027216	Cyanidioschyzon merolae	37.77	3.00e-28	118.00
IUUC-Dre-028356	Danio rerio	88.26	6.00e-122	429.00
IUUC-Dse-031461	Dothistroma septosporum	38.82	3.00e-34	138.00
IUUC-Dme-032146	Drosophila melanogaster	52.44	2.00e-63	234.00
IUUC-Eca-033220	Equus caballus	73.04	7.00e-101	359.00
IUUC-Fca-036421	Felis catus	73.04	1.00e-101	362.00
IUUC-Fal-036773	Ficedula albicollis	74.07	4.00e-88	317.00
IUUC-Fox-037830	Fusarium oxysporum	37.02	8.00e-38	150.00
IUUC-Fso-038259	Fusarium solani	35.96	2.00e-34	141.00
IUUC-Gmo-039468	Gadus morhua	81.74	4.00e-100	357.00
IUUC-Ggr-039832	Gaeumannomyces graminis	38.10	3.00e-36	145.00
IUUC-Gga-041205	Gallus gallus	73.91	1.00e-94	339.00
IUUC-Gac-041629	Gasterosteus aculeatus	80.79	2.00e-105	374.00
IUUC-Gma-043057	Glycine max	46.93	1.00e-50	192.00
IUUC-Ggo-044533	Gorilla gorilla	72.73	3.00e-100	357.00
IUUC-Hsa-046754	Homo sapiens	73.04	1.00e-101	362.00
IUUC-Hvu-047176	Hordeum vulgare	38.53	3.00e-40	158.00
IUUC-Kpa-049123	Komagataella pastoris	36.55	2.00e-29	122.00
IUUC-Lch-049685	Latimeria chalumnae	78.26	1.00e-109	388.00
IUUC-Lpe-051377	Leersia perrieri	44.33	2.00e-45	175.00
IUUC-Loc-051988	Lepisosteus oculatus	87.39	3.00e-120	424.00
IUUC-Lma-053316	Leptosphaeria maculans	39.83	1.00e-42	166.00
IUUC-Laf-053985	Loxodonta africana	73.59	3.00e-101	360.00
IUUC-Mcc-055888	Macaca mulatta	71.74	9.00e-98	349.00
IUUC-Mor-057271	Magnaporthe oryzae	37.93	8.00e-39	153.00
IUUC-Mpo-057343	Magnaporthe poae	31.06	6.00e-19	87.00
IUUC-Mtr-057713	Medicago truncatula	47.81	4.00e-52	197.00
IUUC-Mla-058942	Melampsora laricipopulina	47.14	8.00e-51	193.00
IUUC-Mga-059702	Meleagris gallopavo	74.18	3.00e-87	314.00
IUUC-Mvi-060249	Microbotryum violaceum	43.36	2.00e-39	155.00
IUUC-Mmr-061284	Microcebus murinus	71.52	2.00e-66	245.00
IUUC-Mdo-062639	Monodelphis domestica	63.16	2.00e-95	342.00
IUUC-Mmu-063299	Mus musculus	73.48	8.00e-102	362.00
IUUC-Mac-065075	Musa acuminata	49.13	2.00e-57	214.00
IUUC-Mpu-066769	Mustela putorius furo	73.04	1.00e-101	362.00
IUUC-Mlu-066937	Myotis lucifugus	70.87	4.00e-98	350.00
IUUC-Nfi-068320	Neosartorya fischeri	39.24	1.00e-40	159.00
IUUC-Ncr-068673	Neurospora crassa	39.15	4.00e-41	160.00
IUUC-Nle-069175	Nomascus leucogenys	72.17	4.00e-90	323.00
IUUC-Ont-072170	Oreochromis niloticus	82.53	7.00e-107	379.00
IUUC-Oan-073247	Ornithorhynchus anatinus	72.57	2.00e-46	176.00
IUUC-Ocu-074422	Oryctolagus cuniculus	73.04	9.00e-102	362.00
IUUC-Oba-075098	Oryza barthii	44.93	2.00e-52	198.00
IUUC-Obr-076041	Oryza brachyantha	44.54	3.00e-53	201.00
IUUC-Ogl-076980	Oryza glaberrima	45.85	6.00e-53	200.00
IUUC-Ogu-078978	Oryza glumaepatula	40.55	4.00e-49	187.00
IUUC-Oin-079285	Oryza indica	44.49	1.00e-51	196.00
IUUC-Olo-080671	Oryza longistaminata	44.49	2.00e-51	195.00
IUUC-Ome-081428	Oryza meridionalis	43.61	4.00e-50	191.00
IUUC-Oni-082406	Oryza nivara	44.93	2.00e-52	198.00
IUUC-Opu-083305	Oryza punctata	44.05	3.00e-50	191.00
IUUC-Oru-084969	Oryza rufipogon	44.93	2.00e-52	198.00
IUUC-Osa-085830	Oryza sativa	45.85	6.00e-53	200.00
IUUC-Ola-086893	Oryzias latipes	78.17	1.00e-99	355.00
IUUC-Olu-087858	Ostreococcus lucimarinus	42.92	3.00e-50	191.00
IUUC-Oga-088055	Otolemur garnettii	72.73	3.00e-100	357.00
IUUC-Oar-090319	Ovis aries	72.17	4.00e-101	360.00
IUUC-Pan-092714	Papio anubis	72.29	1.00e-99	355.00
IUUC-Psi-094036	Pelodiscus sinensis	74.54	3.00e-89	320.00
IUUC-Pma-094412	Petromyzon marinus	65.58	3.00e-54	203.00
IUUC-Pno-094997	Phaeosphaeria nodorum	35.55	3.00e-31	128.00
IUUC-Ppa-095519	Physcomitrella patens	52.21	2.00e-66	245.00
IUUC-Pfo-096182	Poecilia formosa	77.49	2.00e-102	364.00
IUUC-Pop-099282	Populus trichocarpa	49.34	6.00e-53	200.00
IUUC-Ppe-101332	Prunus persica	48.90	4.00e-56	211.00
IUUC-Pgr-103430	Puccinia graminis	46.47	1.00e-45	176.00
IUUC-Ptt-103955	Puccinia triticina	47.86	5.00e-47	180.00
IUUC-Pte-104414	Pyrenophora teres	39.57	6.00e-38	150.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	32.77	7.00e-31	127.00
IUUC-Rno-105096	Rattus norvegicus	72.61	2.00e-100	358.00
IUUC-Sce-106412	Saccharomyces cerevisiae	36.22	5.00e-28	117.00
IUUC-Sha-106677	Sarcophilus harrisii	73.61	2.00e-94	338.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	29.07	3.00e-23	101.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	36.64	5.00e-36	144.00
IUUC-Smo-108914	Selaginella moellendorffii	47.86	8.00e-53	199.00
IUUC-Sit-110163	Setaria italica	44.68	3.00e-53	201.00
IUUC-Sly-111613	Solanum lycopersicum	46.49	1.00e-57	216.00
IUUC-Stu-112526	Solanum tuberosum	47.58	2.00e-53	201.00
IUUC-Sbi-114545	Sorghum bicolor	46.09	1.00e-52	199.00
IUUC-Sre-114961	Sporisorium reilianum	40.87	5.00e-40	157.00
IUUC-Ssc-115255	Sus scrofa	72.17	3.00e-92	330.00
IUUC-Tgu-117003	Taeniopygia guttata	73.91	8.00e-94	335.00
IUUC-Tru-118330	Takifugu rubripes	67.21	1.00e-72	267.00
IUUC-Tni-120042	Tetraodon nigroviridis	70.65	3.00e-75	276.00
IUUC-Tca-120976	Theobroma cacao	48.02	1.00e-54	206.00
IUUC-Tre-122149	Trichoderma reesei	39.57	3.00e-38	151.00
IUUC-Tvi-122450	Trichoderma virens	39.57	2.00e-39	155.00
IUUC-Tae-122693	Triticum aestivum	45.45	1.00e-53	203.00
IUUC-Tur-126250	Triticum urartu	43.93	1.00e-51	196.00
IUUC-Tme-126961	Tuber melanosporum	36.91	2.00e-34	139.00
IUUC-Uma-129382	Ustilago maydis	40.52	4.00e-43	167.00
IUUC-Vda-129678	Verticillium dahliae	37.19	3.00e-31	128.00
IUUC-Vpa-130783	Vicugna pacos	69.57	1.00e-44	172.00
IUUC-Vvi-131661	Vitis vinifera	45.18	2.00e-54	205.00
IUUC-Xtr-132428	Xenopus tropicalis	72.17	4.00e-101	360.00
IUUC-Xma-134245	Xiphophorus maculatus	76.42	5.00e-101	359.00
IUUC-Yli-134570	Yarrowia lipolytica	37.45	1.00e-35	142.00
IUUC-Zma-134740	Zea mays	44.35	1.00e-52	199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence