iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055158

Ensembl Protein ID

ENSMMUP00000036246.1

UniProt Accession

F7HET5; F7HET5_MACMU

Genbank Protein ID

ENSMMUP00000036246

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03018197

Gene Name

VPS36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011360.3	ENSMMUT00000043237.2	ENSMMUP00000036246.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/PH/GLUE	1.20e-72	243.5	1	138

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/PH/GLUE

   S: 1    mdrfvytealLeinetlvirqrsvkiydgdekikfdaGellLtthRLiWirdqkneevtlaipLsavvfieeeaaaigksakivvhlhp 89
           mdrfv+t++lLein tlvi+qr+v+iydg+ekikfdaG+llL+thRLiW rdqkn+e+++a++Ls++vfiee+aa+igksakivvhlhp
   Q: 1    MDRFVWTSGLLEINQTLVIQQRGVRIYDGEEKIKFDAGTLLLSTHRLIW-RDQKNHECCMAVLLSQIVFIEEQAAGIGKSAKIVVHLHP 88
           9************************************************.*************************************** PP
   S: 90   arsdkePGpldsskasyiklsfkekgdiefyskLseeltaRaWeelevse 139
           a+++kePGp++ssk+syiklsfke+g+iefy++Lsee+t+R+We+++vs+
   Q: 89   APPNKEPGPFQSSKNSYIKLSFKEHGQIEFYRRLSEEMTQRRWENMPVSQ 138
           ************************************************97 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDRFVWTSGL LEINQTLVIQ QRGVRIYDGE EKIKFDAGTL LLSTHRLIWR DQKNHECCMA 60
VLLSQIVFIE EQAAGIGKSA KIVVHLHPAP PNKEPGPFQS SKNSYIKLSF KEHGQIEFYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGTCCGAC GCTAGGGGGC GCCACAGGCT GCCCGGCTTG CGGCTCGCGG CCCGGGAGCG 60
CCGGGGCTAG GTGGCGGCGG CCATGGACCG ATTCGTTTGG ACCAGCGGCC TCCTGGAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007286--EAP30
IPR021648--GLUE_dom
IPR011993--PH_dom-like
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS51495--GLUE

Pfam

PF04157--EAP30
PF11605--Vps36_ESCRT-II

Gene Ontology

GO:0005829--C:cytosol
GO:0000814--C:ESCRT II complex
GO:0070062--C:extracellular exosome
GO:0031902--C:late endosome membrane
GO:0005764--C:lysosome
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0043130--F:ubiquitin binding
GO:0043328--P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

mcc:693290

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000963	Aegilops tauschii	41.88	6.00e-35	140.00
IUUC-Aml-002313	Ailuropoda melanoleuca	97.67	0.00e+00	753.00
IUUC-Atr-003096	Amborella trichopoda	36.05	2.00e-15	76.30
IUUC-Apl-003218	Anas platyrhynchos	87.93	0.00e+00	679.00
IUUC-Aca-004580	Anolis carolinensis	89.90	0.00e+00	698.00
IUUC-Aly-006398	Arabidopsis lyrata	38.34	2.00e-57	216.00
IUUC-Ath-006907	Arabidopsis thaliana	37.63	4.00e-57	215.00
IUUC-Ago-007840	Ashbya gossypii	22.08	2.00e-04	40.40
IUUC-Acl-008117	Aspergillus clavatus	32.21	3.00e-36	146.00
IUUC-Afl-008595	Aspergillus flavus	32.04	2.00e-36	147.00
IUUC-Afu-008918	Aspergillus fumigatus	31.61	7.00e-36	145.00
IUUC-Ani-009206	Aspergillus nidulans	32.94	4.00e-36	146.00
IUUC-Ang-009784	Aspergillus niger	32.62	4.00e-33	136.00
IUUC-Aor-010126	Aspergillus oryzae	32.56	2.00e-36	147.00
IUUC-Ate-010303	Aspergillus terreus	33.13	2.00e-34	140.00
IUUC-Ame-011190	Astyanax mexicanus	84.55	0.00e+00	662.00
IUUC-Bgr-011979	Blumeria graminis	31.46	4.00e-33	136.00
IUUC-Bta-012661	Bos taurus	97.67	0.00e+00	750.00
IUUC-Bci-013982	Botrytis cinerea	32.97	4.00e-33	136.00
IUUC-Bdi-014753	Brachypodium distachyon	40.21	5.00e-51	195.00
IUUC-Bol-015465	Brassica oleracea	42.25	1.00e-49	190.00
IUUC-Bra-016794	Brassica rapa	42.69	1.00e-50	194.00
IUUC-Cel-018514	Caenorhabditis elegans	41.86	2.00e-81	296.00
IUUC-Cja-019285	Callithrix jacchus	98.02	0.00e+00	687.00
IUUC-Cfa-020746	Canis familiaris	98.45	0.00e+00	758.00
IUUC-Cpo-022005	Cavia porcellus	97.18	0.00e+00	686.00
IUUC-Cre-022686	Chlamydomonas reinhardtii	35.63	6.00e-33	135.00
IUUC-Csa-023520	Chlorocebus sabaeus	99.74	0.00e+00	767.00
IUUC-Cho-024957	Choloepus hoffmanni	93.26	0.00e+00	713.00
IUUC-Cin-025575	Ciona intestinalis	45.24	1.00e-07	47.40
IUUC-Csv-025942	Ciona savignyi	52.85	6.00e-108	384.00
IUUC-Cgl-026558	Colletotrichum gloeosporioides	32.14	9.00e-31	128.00
IUUC-Cne-026915	Cryptococcus neoformans	27.97	1.00e-23	104.00
IUUC-Cme-027099	Cyanidioschyzon merolae	24.68	8.00e-12	65.10
IUUC-Dre-027753	Danio rerio	84.29	0.00e+00	660.00
IUUC-Dno-029922	Dasypus novemcinctus	95.34	0.00e+00	738.00
IUUC-Dor-030643	Dipodomys ordii	90.16	0.00e+00	683.00
IUUC-Dse-031368	Dothistroma septosporum	32.08	2.00e-29	124.00
IUUC-Dme-031977	Drosophila melanogaster	44.86	4.00e-92	331.00
IUUC-Ete-033135	Echinops telfairi	75.07	7.00e-142	496.00
IUUC-Eca-033937	Equus caballus	97.46	0.00e+00	690.00
IUUC-Eeu-034483	Erinaceus europaeus	93.01	0.00e+00	741.00
IUUC-Fca-035496	Felis catus	97.74	0.00e+00	687.00
IUUC-Fal-036743	Ficedula albicollis	89.90	0.00e+00	700.00
IUUC-Fox-037685	Fusarium oxysporum	34.80	8.00e-27	115.00
IUUC-Fso-038421	Fusarium solani	31.19	1.00e-28	121.00
IUUC-Gmo-039456	Gadus morhua	78.85	1.00e-174	605.00
IUUC-Ggr-039763	Gaeumannomyces graminis	31.72	8.00e-36	145.00
IUUC-Gga-040556	Gallus gallus	89.12	0.00e+00	694.00
IUUC-Gac-041481	Gasterosteus aculeatus	80.47	1.00e-159	555.00
IUUC-Gma-044185	Glycine max	44.26	5.00e-53	201.00
IUUC-Ggo-044849	Gorilla gorilla	99.48	0.00e+00	766.00
IUUC-Hsa-046228	Homo sapiens	99.48	0.00e+00	766.00
IUUC-Hvu-047858	Hordeum vulgare	39.62	3.00e-13	68.90
IUUC-Itr-048068	Ictidomys tridecemlineatus	94.85	0.00e+00	728.00
IUUC-Kpa-049240	Komagataella pastoris	26.51	1.00e-05	45.10
IUUC-Lch-050293	Latimeria chalumnae	87.74	1.00e-125	442.00
IUUC-Lpe-051363	Leersia perrieri	45.08	2.00e-51	196.00
IUUC-Loc-052866	Lepisosteus oculatus	84.72	0.00e+00	642.00
IUUC-Lma-053139	Leptosphaeria maculans	29.19	7.00e-32	132.00
IUUC-Laf-053881	Loxodonta africana	91.71	0.00e+00	701.00
IUUC-Meu-056126	Macropus eugenii	74.58	1.00e-136	479.00
IUUC-Mor-057092	Magnaporthe oryzae	31.25	7.00e-33	135.00
IUUC-Mpo-057629	Magnaporthe poae	31.88	9.00e-28	117.00
IUUC-Mtr-058039	Medicago truncatula	44.86	1.00e-53	203.00
IUUC-Mla-058913	Melampsora laricipopulina	30.87	1.00e-23	104.00
IUUC-Mga-059956	Meleagris gallopavo	89.12	0.00e+00	696.00
IUUC-Mvi-060570	Microbotryum violaceum	23.92	3.00e-17	83.60
IUUC-Mmr-061769	Microcebus murinus	98.31	0.00e+00	691.00
IUUC-Mdo-062751	Monodelphis domestica	91.12	0.00e+00	710.00
IUUC-Mmu-063115	Mus musculus	95.34	0.00e+00	743.00
IUUC-Mac-064979	Musa acuminata	35.58	9.00e-53	201.00
IUUC-Mpu-066904	Mustela putorius furo	97.89	8.00e-139	485.00
IUUC-Mlu-067474	Myotis lucifugus	96.89	0.00e+00	745.00
IUUC-Nfi-068588	Neosartorya fischeri	32.21	9.00e-33	135.00
IUUC-Ncr-068855	Neurospora crassa	29.71	2.00e-27	117.00
IUUC-Nle-069660	Nomascus leucogenys	98.70	0.00e+00	761.00
IUUC-Opr-070695	Ochotona princeps	95.85	0.00e+00	738.00
IUUC-Ont-071837	Oreochromis niloticus	83.25	5.00e-174	603.00
IUUC-Oan-072903	Ornithorhynchus anatinus	92.98	0.00e+00	663.00
IUUC-Ocu-074833	Oryctolagus cuniculus	97.15	0.00e+00	750.00
IUUC-Oba-075899	Oryza barthii	45.42	1.00e-51	196.00
IUUC-Obr-076125	Oryza brachyantha	36.00	2.00e-55	209.00
IUUC-Ogl-077538	Oryza glaberrima	50.00	2.00e-32	133.00
IUUC-Ogu-078272	Oryza glumaepatula	45.08	1.00e-51	197.00
IUUC-Oin-079158	Oryza indica	44.35	4.00e-51	195.00
IUUC-Olo-080496	Oryza longistaminata	44.17	1.00e-47	183.00
IUUC-Ome-081440	Oryza meridionalis	44.77	2.00e-49	188.00
IUUC-Oni-083069	Oryza nivara	44.35	4.00e-51	195.00
IUUC-Opu-083838	Oryza punctata	45.53	5.00e-50	191.00
IUUC-Oru-084377	Oryza rufipogon	45.08	1.00e-51	197.00
IUUC-Osa-085976	Oryza sativa	45.08	1.00e-51	197.00
IUUC-Ola-086431	Oryzias latipes	84.55	6.00e-177	613.00
IUUC-Olu-087789	Ostreococcus lucimarinus	39.30	2.00e-39	155.00
IUUC-Oga-089152	Otolemur garnettii	97.15	0.00e+00	748.00
IUUC-Oar-089198	Ovis aries	97.74	0.00e+00	686.00
IUUC-Ptr-091123	Pan troglodytes	99.48	0.00e+00	766.00
IUUC-Pan-092866	Papio anubis	96.12	0.00e+00	736.00
IUUC-Psi-093384	Pelodiscus sinensis	93.52	0.00e+00	723.00
IUUC-Pno-094773	Phaeosphaeria nodorum	31.31	2.00e-27	117.00
IUUC-Ppa-095753	Physcomitrella patens	36.20	5.00e-56	211.00
IUUC-Pfo-096028	Poecilia formosa	83.25	7.00e-176	609.00
IUUC-Pop-098915	Populus trichocarpa	44.86	1.00e-52	200.00
IUUC-Pca-100422	Procavia capensis	94.35	0.00e+00	660.00
IUUC-Ppe-101564	Prunus persica	44.90	8.00e-54	204.00
IUUC-Pva-103019	Pteropus vampyrus	92.49	0.00e+00	701.00
IUUC-Pgr-103670	Puccinia graminis	28.05	3.00e-20	94.00
IUUC-Ptt-103958	Puccinia triticina	26.77	3.00e-19	89.40
IUUC-Pte-104343	Pyrenophora teres	31.52	9.00e-38	151.00
IUUC-Pyt-104554	Pyrenophora triticirepentis	31.34	2.00e-39	157.00
IUUC-Rno-105775	Rattus norvegicus	95.60	0.00e+00	742.00
IUUC-Sce-106148	Saccharomyces cerevisiae	22.29	1.00e-02	35.00
IUUC-Sha-106468	Sarcophilus harrisii	93.22	0.00e+00	657.00
IUUC-Sja-107850	Schizosaccharomyces japonicus	23.51	1.00e-16	80.90
IUUC-Spo-108225	Schizosaccharomyces pombe	23.37	2.00e-17	83.60
IUUC-Ssl-108412	Sclerotinia sclerotiorum	32.35	2.00e-30	127.00
IUUC-Smo-109001	Selaginella moellendorffii	35.33	1.00e-53	203.00
IUUC-Sit-110126	Setaria italica	39.79	6.00e-49	188.00
IUUC-Sly-110884	Solanum lycopersicum	36.07	7.00e-52	197.00
IUUC-Stu-112573	Solanum tuberosum	35.62	3.00e-52	199.00
IUUC-Sar-113114	Sorex araneus	94.03	8.00e-71	260.00
IUUC-Sbi-114331	Sorghum bicolor	29.86	7.00e-38	151.00
IUUC-Sre-115135	Sporisorium reilianum	22.91	1.00e-09	58.50
IUUC-Ssc-116158	Sus scrofa	98.19	0.00e+00	757.00
IUUC-Tgu-116962	Taeniopygia guttata	89.64	0.00e+00	670.00
IUUC-Tru-117567	Takifugu rubripes	82.98	3.00e-175	607.00
IUUC-Tsy-119357	Tarsius syrichta	81.87	1.00e-167	582.00
IUUC-Tni-120047	Tetraodon nigroviridis	83.09	1.00e-155	542.00
IUUC-Tca-121097	Theobroma cacao	44.86	1.00e-53	203.00
IUUC-Tre-122075	Trichoderma reesei	30.14	2.00e-33	137.00
IUUC-Tvi-122623	Trichoderma virens	32.54	2.00e-39	157.00
IUUC-Tae-123728	Triticum aestivum	43.44	5.00e-51	195.00
IUUC-Tur-125988	Triticum urartu	42.35	1.00e-40	160.00
IUUC-Tme-126936	Tuber melanosporum	31.11	8.00e-34	138.00
IUUC-Tbe-127481	Tupaia belangeri	67.80	2.00e-128	452.00
IUUC-Ttr-128160	Tursiops truncatus	96.89	0.00e+00	738.00
IUUC-Uma-129428	Ustilago maydis	24.83	7.00e-17	82.40
IUUC-Vda-129877	Verticillium dahliae	32.08	5.00e-29	122.00
IUUC-Vpa-130358	Vicugna pacos	97.74	0.00e+00	682.00
IUUC-Vvi-131406	Vitis vinifera	36.97	1.00e-56	214.00
IUUC-Xtr-132548	Xenopus tropicalis	84.75	0.00e+00	649.00
IUUC-Xma-133352	Xiphophorus maculatus	83.51	5.00e-176	610.00
IUUC-Yli-134466	Yarrowia lipolytica	30.77	3.00e-20	92.80
IUUC-Zma-135081	Zea mays	40.14	7.00e-51	194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence