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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063578
UUCD1 version UUC-MuM-01131
Ensembl Protein ID ENSMUSP00000035216.4
UniProt Accession Q9DBK7; Q9DBK7_MOUSE
Genbank Protein ID AAI38844.1; BAB23650.1; EDL21244.1
Protein Name MCG18845, isoform CRA_d; Putative uncharacterized protein; Ubiquitin-activating enzyme E1-like; Ubiquitin-like modifier-activating enzyme 7
Genbank Nucleotide ID AL731808; AK004894; CH466560
Gene Name Uba7; Ube1l; mCG_18845
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000032596.14 ENSMUST00000035216.10 ENSMUSP00000035216.4
ENSMUSG00000032596.14 ENSMUST00000177392.7 ENSMUSP00000134910.1
ENSMUSG00000032596.14 ENSMUST00000177039.7 ENSMUSP00000135584.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E1 2.00e-188 627.8 402 854
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E1
   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Qi+++G + qekl+ +++llvGag++GcE+lK ++l+G+     g +tv Dmd +e snl+rqFLfr++dv ++KAevaa+a+++l
   Q: 402  YDGQIAVFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLgvranGGVTVADMDYIERSNLSRQFLFRPKDVRRPKAEVAAAAAHRL 490
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd...dpp 167
           npd +++++++++++++e+i+   Ff+++++Vv+ald+++ar +v+ +c+++ +pl+e+gt G++G ++v+++++te+y+ +     ++
   Q: 491  NPDLRATPYTCPLDPTTEDIYddsFFSRVNGVVAALDSFQARHYVAARCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPAsdaASE 579
           *********************************************************************************99988999 PP
   S: 168  qktiPfctlketpnaaehtiewa........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakt 248
           +  +P+ctl++ p+  eh+++wa        +l  ++++ +++  + l+ +d++e+++ +++v   l++ +++++++++ +a+ +++ +
   Q: 580  DAPYPVCTLRHIPSSMEHSVQWAqdqfeglfRLSTETINCYQQTCTSLSATDRTETLALLQQVMGVLRT-RPQTWQDCVVWALGHWQLC 667
           999****************************9*******************************666555.7****************** PP
   S: 249  tinsikqllksfecdivtkskspfwv.....................................sfcsnaealq.....vpekvekdeev 295
           ++ ++ +    f+ +    +k p+ +                                                    ++++    + +
   Q: 668  FHDKVLEGGTQFSSGS---NKCPHPLqfdpnhdmhflyvlaaanlyarmhglpgsqsqpalreL--------LtrlleSDSRPQNLFSA 745
           **99776666666655...677777745666666666666666666666666666555543322........03322233444444444 PP
   S: 296  vkasaplylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaq 382
            + +++l+ l ++l+ ++k + +kp  + f kddds  +vd+v aa  lr++++gi p ++  +ik+i+g+iipaiat +avv+Gl+ +
   Q: 746  EHGQEQLKELQETLDDWRKGPPLKP--VLFVKDDDSnfHVDFVVAATDLRCQNYGILP-VNHARIKQIVGRIIPAIATSTAVVAGLLGL 831
           444555999***************9..78888888889********************.****************************** PP
   S: 383  EviKvvsg..kfeplknfflfda 403
           E++Kvvsg      +++ +l++a
   Q: 832  ELYKVVSGlrSHGTFRHSYLHLA 854
           *******9544444777777665 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MDEELYSRQL YVLGLPAMQR IQEAKVLLCG LQGLGAEVAK NLVLTGVGSL TLHDPHPTCW 60
ADLAAQCFLS EESLGRNRAE ASQAQLAQLN EAVQISVHSG DITEDLLQGF QVVVLTDSKL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063578|E1,E1_ThiF|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTCACTGGG AGGACCAGGA ACCAACTCAG TCTAGTTTCA CTTTTGGTTT CCTGAAATCA 60
TAGAGGAAGC AGAAAGAGAG CTGTAACCAG CAGCAACCAG CGCTTTGGGG CCTGTTTGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063578|E1,E1_ThiF|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like
Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys
PRINTS

PR01849--UBIQUITINACT
SMART

SM00985--UBA_e1_C
Gene Ontology

GO:0019782--F:ISG15 activating enzyme activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006464--P:cellular protein modification process
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process
KEGG mmu:74153
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001816 Ailuropoda melanoleuca 70.27 0.00e+00 1291.00
IUUC-Bta-012665 Bos taurus 67.90 0.00e+00 1190.00
IUUC-Cja-019047 Callithrix jacchus 71.33 0.00e+00 1303.00
IUUC-Cfa-021225 Canis familiaris 71.27 0.00e+00 1355.00
IUUC-Cpo-022336 Cavia porcellus 66.43 0.00e+00 1211.00
IUUC-Csa-023462 Chlorocebus sabaeus 74.28 0.00e+00 1314.00
IUUC-Cho-024436 Choloepus hoffmanni 67.51 8.00e-88 318.00
IUUC-Dno-029347 Dasypus novemcinctus 70.59 0.00e+00 1271.00
IUUC-Dor-030997 Dipodomys ordii 70.97 0.00e+00 1315.00
IUUC-Ete-033124 Echinops telfairi 69.64 0.00e+00 907.00
IUUC-Eca-033929 Equus caballus 71.91 0.00e+00 1398.00
IUUC-Eeu-034717 Erinaceus europaeus 64.95 0.00e+00 884.00
IUUC-Fca-036564 Felis catus 71.00 0.00e+00 1296.00
IUUC-Ggo-044480 Gorilla gorilla 73.45 0.00e+00 1308.00
IUUC-Hsa-046498 Homo sapiens 72.78 0.00e+00 1296.00
IUUC-Itr-048657 Ictidomys tridecemlineatus 71.47 0.00e+00 1307.00
IUUC-Laf-054119 Loxodonta africana 68.73 0.00e+00 1309.00
IUUC-Mcc-055597 Macaca mulatta 72.81 0.00e+00 1269.00
IUUC-Mdo-063058 Monodelphis domestica 53.45 0.00e+00 974.00
IUUC-Mpu-066255 Mustela putorius furo 68.76 0.00e+00 1259.00
IUUC-Mlu-067814 Myotis lucifugus 67.76 0.00e+00 1150.00
IUUC-Nle-069193 Nomascus leucogenys 73.55 0.00e+00 1317.00
IUUC-Opr-070715 Ochotona princeps 66.20 0.00e+00 1208.00
IUUC-Ocu-074162 Oryctolagus cuniculus 69.45 0.00e+00 1270.00
IUUC-Oga-088895 Otolemur garnettii 70.11 0.00e+00 1253.00
IUUC-Oar-089579 Ovis aries 66.70 0.00e+00 1172.00
IUUC-Ptr-090581 Pan troglodytes 72.51 0.00e+00 1277.00
IUUC-Pan-092458 Papio anubis 74.18 0.00e+00 1305.00
IUUC-Pab-098653 Pongo abelii 68.69 0.00e+00 1232.00
IUUC-Pca-100578 Procavia capensis 65.52 0.00e+00 764.00
IUUC-Pva-102914 Pteropus vampyrus 68.75 0.00e+00 1060.00
IUUC-Rno-106066 Rattus norvegicus 86.19 0.00e+00 1686.00
IUUC-Sha-107368 Sarcophilus harrisii 56.27 0.00e+00 1051.00
IUUC-Ssc-115743 Sus scrofa 71.10 0.00e+00 1319.00
IUUC-Tbe-127587 Tupaia belangeri 72.60 0.00e+00 978.00
Created Date 25-Jun-2017

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