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Tag Content
UUCD2 ID IUUC-Itr-048525
UUCD1 version UUC-SpT-00023
Ensembl Protein ID ENSSTOP00000008566.2
UniProt Accession I3MDR6; I3MDR6_ICTTR
Genbank Protein ID ENSSTOP00000008566
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTP01010823
Gene Name CUL7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000009522.2 ENSSTOT00000009550.2 ENSSTOP00000008566.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 2.90e-146 488.7 953 1494
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 70   nreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveL 156
            ++W+ freql++++++f      y+++           +++w+++i+ed +++ll+l+++l+ a+R+++++++++l++++++    
   Q: 953  PTFWPVFREQLCRHTRLF------YMVR-----------AQAWSQDIAED-RRSLLHLSSRLNGALRQEQNFADHFLPDDEAA---- 1017
           689***************......****...........***********.********************************.... PP
   S: 157  slnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllae 242
               +a++k+++Ea++++ +q++++++++ ++   + +d+Yl+++ea+ n+++++aa++++++++t+Ll++ve++++a       ++
   Q: 1018 ----QALGKTCWEALVSPLVQNITSPDEDGISPLgWLLDQYLECREASHNPQSRAAAFSSRVRRLTHLLVHVEPCEMA-------PP 1093
           ....**************************************************************************.......** PP
   S: 243  lvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlk 327
           +va +r k++++ +++++L++r+l+  ++++l+++++++++eq++++lt+ ++++d   +V+r++e+++ lqk++se+F+++a+Fl 
   Q: 1094 VVAAPRPKGRNRSHDWSSLATRGLPssIMRNLTRCWQAVVEEQVNNFLTSYWRDND---FVPRYCEHYYNLQKSSSELFGPRAAFLL 1177
           ************************999*****************************...**************************** PP
   S: 328  aldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLlsgksa 410
           al+++++ ++++ s+l+aa+++E++Ar+iDq++++s ++g++++e++aql+++l+ +  +s++++   Fe+yY++++a+RLl   + 
   Q: 1178 ALQNGCAGALLRLSFLRAAHVSEQFARHIDQRIQGSrIGGARGMEMLAQLQRCLETVLNFSGLEIattFEHYYQQYMADRLLG--VG 1262
           ***********************************************************************************..** PP
   S: 411  sseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk............................................ 452
           ss++E++v+e++    g++f+++L ++M+++l++Se+l+rqF+                                            
   Q: 1263 SSWLEGAVLEQI----GPCFPNRLpQQMLRSLSTSEELQRQFHvyqlqqldqellkledtekkiqvgheasgkehkngkeedageav 1345
           ************....*********************************************************************** PP
   S: 453  ..........eekenteesesvelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLqWqhtl 517
                     e+++ ++e +++e+svlvLs+++Wp+a  +++  + ++LP++l+ t++++++fY        le++s+R+LqW++ l
   Q: 1346 aadvvegeeeENEDLYYEGAMPEVSVLVLSPRCWPVAsiCHMlnPGTCLPSYLRGTLNRYSNFYnksqrhpaLERGSQRQLQWTW-L 1431
           ********99899999*********************999999999***************************************.* PP
   S: 518  graelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqv 582
           grae+++    g ++l+Vst+Qm++LL +nn ++vsve+l + ++lp e+L++++++L+ss+   ++
   Q: 1432 GRAEVQF----GDQTLHVSTMQMWLLLNLNNLKAVSVESLLALSGLPLEMLNQAIGPLTSSRgpLDL 1494
           *******....*************************************************9944444 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MVGELRYREF RVPLGPGLHA YPDELIRQRV GHDGHPEYQI RWLILRRGDD GEGASSQVDC 60
KAEHILLWMS DDEIYANCHK MLGEDGQVIG PSRESAEAGA LDKTVLGEME TDVKSLIQRA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-048525|E3,Cullin|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTGGGGG AACTCCGCTA CAGGGAATTC AGGGTGCCCC TTGGGCCTGG CTTGCATGCC 60
TATCCTGATG AGCTGATCCG CCAACGGGTG GGCCATGATG GGCACCCTGA GTACCAGATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-048525|E3,Cullin|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021097--CPH_domain
IPR031223--CUL7
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS50069--CULLIN_2
PS51284--DOC
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
SMART

SM01337--APC10
SM00884--Cullin_Nedd8
Gene Ontology

GO:1990393--C:3M complex
GO:0005813--C:centrosome
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0001837--P:epithelial to mesenchymal transition
GO:0000226--P:microtubule cytoskeleton organization
GO:0000281--P:mitotic cytokinesis
GO:0001890--P:placenta development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0001570--P:vasculogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002360 Ailuropoda melanoleuca 86.78 0.00e+00 2767.00
IUUC-Bta-013285 Bos taurus 83.82 0.00e+00 2699.00
IUUC-Cja-019033 Callithrix jacchus 83.25 0.00e+00 2612.00
IUUC-Cfa-020695 Canis familiaris 86.89 0.00e+00 1717.00
IUUC-Cpo-021513 Cavia porcellus 80.73 0.00e+00 2532.00
IUUC-Csa-023798 Chlorocebus sabaeus 87.05 0.00e+00 2719.00
IUUC-Dno-029587 Dasypus novemcinctus 83.01 0.00e+00 1501.00
IUUC-Dor-030234 Dipodomys ordii 86.17 0.00e+00 2810.00
IUUC-Ete-032612 Echinops telfairi 78.97 0.00e+00 892.00
IUUC-Eca-033408 Equus caballus 87.61 0.00e+00 2735.00
IUUC-Fca-035483 Felis catus 86.95 0.00e+00 2753.00
IUUC-Gmo-038795 Gadus morhua 45.94 0.00e+00 939.00
IUUC-Gac-041628 Gasterosteus aculeatus 45.40 0.00e+00 1290.00
IUUC-Ggo-044721 Gorilla gorilla 86.99 0.00e+00 2725.00
IUUC-Hsa-046406 Homo sapiens 87.05 0.00e+00 2744.00
IUUC-Lch-049956 Latimeria chalumnae 43.59 0.00e+00 1035.00
IUUC-Laf-054068 Loxodonta africana 86.02 0.00e+00 2753.00
IUUC-Mcc-055464 Macaca mulatta 86.87 0.00e+00 2702.00
IUUC-Meu-056198 Macropus eugenii 55.83 0.00e+00 1588.00
IUUC-Mmr-061464 Microcebus murinus 86.27 0.00e+00 2690.00
IUUC-Mdo-062018 Monodelphis domestica 58.52 0.00e+00 1411.00
IUUC-Mmu-063413 Mus musculus 80.05 0.00e+00 2462.00
IUUC-Mpu-066146 Mustela putorius furo 88.21 0.00e+00 2712.00
IUUC-Mlu-067036 Myotis lucifugus 85.12 0.00e+00 2715.00
IUUC-Opr-070670 Ochotona princeps 78.83 0.00e+00 2479.00
IUUC-Oan-073451 Ornithorhynchus anatinus 50.11 0.00e+00 1155.00
IUUC-Ocu-074155 Oryctolagus cuniculus 85.33 0.00e+00 2682.00
IUUC-Oga-089084 Otolemur garnettii 85.97 0.00e+00 2783.00
IUUC-Oar-090029 Ovis aries 85.54 0.00e+00 2723.00
IUUC-Ptr-091282 Pan troglodytes 85.62 0.00e+00 2728.00
IUUC-Pan-091883 Papio anubis 87.10 0.00e+00 2737.00
IUUC-Pab-098383 Pongo abelii 84.00 0.00e+00 2662.00
IUUC-Pca-100519 Procavia capensis 85.31 0.00e+00 811.00
IUUC-Pva-102417 Pteropus vampyrus 83.94 0.00e+00 2161.00
IUUC-Rno-105962 Rattus norvegicus 81.82 0.00e+00 2613.00
IUUC-Sar-113750 Sorex araneus 79.90 1.00e-169 590.00
IUUC-Ssc-115899 Sus scrofa 80.12 0.00e+00 2437.00
IUUC-Tsy-118860 Tarsius syrichta 83.88 0.00e+00 1097.00
IUUC-Tbe-127660 Tupaia belangeri 82.65 0.00e+00 1409.00
Created Date 25-Jun-2017

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