iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002286

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01114386

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000012836.1	ENSAMET00000014086.1	ENSAMEP00000013524.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.50e-06	27.2	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ +  Cl +w     + s +++CP Cr
   Q: 351  CKICAESNKD-VKIEPCGHLLCSRCLAAW-----QHSDSQTCPFCR 390
           99********.******************.....6889999****8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAAAAAPWGR QWGEARALGR AVRMLQCLDE QCGDPRLASS PPSLRDLLPR LAQLLRQVAH 60
ARRAAGGGGP EGPGGARDFL IVYLHNLEAK SRQVAALLPP RGGKSANDEL FREGSRLRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCGG CGGCCGCCCC CTGGGGGCGG CAGTGGGGCG AGGCCCGCGC GCTTGGCCGG 60
GCGGTGAGAA TGCTGCAGTG CCTGGATGAG CAATGCGGGG ACCCCCGGCT TGCCTCCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012705	Bos taurus	80.96	0.00e+00	714.00
IUUC-Cja-019179	Callithrix jacchus	80.37	0.00e+00	677.00
IUUC-Cfa-020593	Canis familiaris	88.44	0.00e+00	777.00
IUUC-Cpo-021289	Cavia porcellus	76.12	6.00e-174	603.00
IUUC-Csa-023966	Chlorocebus sabaeus	77.76	0.00e+00	659.00
IUUC-Dor-030246	Dipodomys ordii	78.03	5.00e-128	450.00
IUUC-Eca-033921	Equus caballus	74.84	2.00e-153	535.00
IUUC-Fca-035747	Felis catus	71.74	0.00e+00	642.00
IUUC-Fox-037671	Fusarium oxysporum	46.88	3.00e-05	42.00
IUUC-Ggo-044622	Gorilla gorilla	85.13	1.00e-156	545.00
IUUC-Hsa-045735	Homo sapiens	84.30	0.00e+00	697.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	76.85	2.00e-174	605.00
IUUC-Laf-053983	Loxodonta africana	77.64	0.00e+00	705.00
IUUC-Mmr-061310	Microcebus murinus	75.62	0.00e+00	659.00
IUUC-Mmu-064155	Mus musculus	68.61	0.00e+00	652.00
IUUC-Mpu-066655	Mustela putorius furo	87.79	0.00e+00	798.00
IUUC-Mlu-067929	Myotis lucifugus	85.81	2.00e-156	544.00
IUUC-Nle-070065	Nomascus leucogenys	70.67	8.00e-160	556.00
IUUC-Ocu-074049	Oryctolagus cuniculus	76.76	5.00e-128	450.00
IUUC-Oga-087952	Otolemur garnettii	82.42	0.00e+00	702.00
IUUC-Oar-089382	Ovis aries	78.36	0.00e+00	676.00
IUUC-Ptr-090579	Pan troglodytes	70.15	2.00e-122	432.00
IUUC-Pan-092075	Papio anubis	82.22	0.00e+00	644.00
IUUC-Pab-098100	Pongo abelii	73.44	3.00e-170	590.00
IUUC-Pca-100830	Procavia capensis	81.42	4.00e-113	401.00
IUUC-Pva-102714	Pteropus vampyrus	79.37	1.00e-168	586.00
IUUC-Rno-105348	Rattus norvegicus	70.22	0.00e+00	656.00
IUUC-Sha-107138	Sarcophilus harrisii	70.88	4.00e-123	434.00
IUUC-Ssc-116424	Sus scrofa	80.04	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence