iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062688

Ensembl Protein ID

ENSMODP00000035281.1

UniProt Accession

F6ZQH8; F6ZQH8_MONDO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000018544.3	ENSMODT00000036869.2	ENSMODP00000035281.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-29	100.6	1186	1220
UBD/Beta-Prp	4.80e-44	150.9	1287	1502

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1186 GHTKAVLCIDSTDDLLFTGSKDRTCKVWNLVTGQE 1220
           8999****99766*****************99976 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqcle 130
           ++ + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g    
   Q: 1287 TIPSGENQINQIALNPNG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisNGqDLIITGSKDHYIKMFDVTEGALGT 1372
           56677899*********9.99**************************************9888*****************9998765 PP
   S: 131  e.....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
                 ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l + + ++ l+sg + g +klw++ t 
   Q: 1373 VspthnFEPPHYDGIEALTIQG--DNLFSGSRDNGIKKWDLSQKDLLQQVPNAHKDWVCALGMVPGQPALLSGCRGGILKLWNVDTF 1457
           4677889999999999999999..7799**********************999********************************** PP
   S: 213  ecvrtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdl 256
             v +++gh+++++ + +   ++ + ++++D ++riW   +l+ g++
   Q: 1458 APVGEMKGHDSPINAICVN--TTQIFTAADDHTVRIWkarNLQDGQI 1502
           **************88888..9***************8888888876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

LYNEEVLDLF DTTRDIDAKN KKSNIRIHED STGGIYTVGV TTRNVNTESE MMQCLKLGAL 60
SRTTASTQMN VQSSRSHAIF TIHLCQTRVC PKIDAENTVD NKMTSESPEM NEYETLTAKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATTCATCA AGGCTAAGAT TTTCCACCAT TTTACTTTGC TAGCTTTATA ATGAAGAGGT 60
TCTTGACCTT TTTGATACCA CACGTGACAT TGATGCTAAA AACAAAAAAT CAAATATAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	89.65	0.00e+00	2624.00
IUUC-Apl-003353	Anas platyrhynchos	83.04	0.00e+00	2352.00
IUUC-Aca-004467	Anolis carolinensis	82.32	0.00e+00	2465.00
IUUC-Ame-011237	Astyanax mexicanus	71.33	0.00e+00	1296.00
IUUC-Bta-013485	Bos taurus	89.18	0.00e+00	2558.00
IUUC-Cja-019385	Callithrix jacchus	88.93	0.00e+00	2550.00
IUUC-Cfa-020986	Canis familiaris	91.79	0.00e+00	1837.00
IUUC-Cpo-022297	Cavia porcellus	87.78	0.00e+00	2501.00
IUUC-Csa-023685	Chlorocebus sabaeus	91.22	0.00e+00	1826.00
IUUC-Cho-024531	Choloepus hoffmanni	90.58	0.00e+00	807.00
IUUC-Cin-025160	Ciona intestinalis	47.20	4.00e-86	312.00
IUUC-Dre-028532	Danio rerio	63.64	0.00e+00	1268.00
IUUC-Dno-029972	Dasypus novemcinctus	86.60	0.00e+00	1654.00
IUUC-Ete-032872	Echinops telfairi	76.88	0.00e+00	1006.00
IUUC-Eca-033518	Equus caballus	89.63	0.00e+00	2603.00
IUUC-Fca-036197	Felis catus	91.40	0.00e+00	1824.00
IUUC-Fal-037534	Ficedula albicollis	84.49	0.00e+00	1695.00
IUUC-Gmo-039407	Gadus morhua	65.78	0.00e+00	1851.00
IUUC-Gga-040687	Gallus gallus	81.09	0.00e+00	2327.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.46	0.00e+00	1959.00
IUUC-Ggo-044457	Gorilla gorilla	91.22	0.00e+00	1832.00
IUUC-Hsa-046372	Homo sapiens	91.60	0.00e+00	1838.00
IUUC-Lch-049786	Latimeria chalumnae	57.69	0.00e+00	1632.00
IUUC-Loc-052689	Lepisosteus oculatus	72.75	0.00e+00	2128.00
IUUC-Laf-054018	Loxodonta africana	85.45	0.00e+00	2406.00
IUUC-Mcc-055558	Macaca mulatta	89.70	0.00e+00	2598.00
IUUC-Meu-056080	Macropus eugenii	92.90	0.00e+00	1044.00
IUUC-Mga-059283	Meleagris gallopavo	83.68	0.00e+00	2396.00
IUUC-Mmr-060773	Microcebus murinus	88.39	0.00e+00	2512.00
IUUC-Mmu-063997	Mus musculus	87.36	0.00e+00	2476.00
IUUC-Mpu-066354	Mustela putorius furo	88.59	0.00e+00	2583.00
IUUC-Mlu-067599	Myotis lucifugus	88.62	0.00e+00	2551.00
IUUC-Nle-069477	Nomascus leucogenys	91.51	0.00e+00	1835.00
IUUC-Opr-070188	Ochotona princeps	82.03	0.00e+00	1593.00
IUUC-Ont-071717	Oreochromis niloticus	60.92	0.00e+00	1655.00
IUUC-Oan-073055	Ornithorhynchus anatinus	88.94	0.00e+00	2407.00
IUUC-Ocu-074302	Oryctolagus cuniculus	88.03	0.00e+00	2514.00
IUUC-Ola-086604	Oryzias latipes	66.10	0.00e+00	1880.00
IUUC-Oga-088799	Otolemur garnettii	89.18	0.00e+00	2579.00
IUUC-Oar-089629	Ovis aries	87.21	0.00e+00	2533.00
IUUC-Pan-092214	Papio anubis	91.31	0.00e+00	1829.00
IUUC-Psi-093757	Pelodiscus sinensis	80.47	0.00e+00	2246.00
IUUC-Pfo-096978	Poecilia formosa	64.91	0.00e+00	1323.00
IUUC-Pab-097984	Pongo abelii	91.51	0.00e+00	1816.00
IUUC-Pca-101061	Procavia capensis	77.00	0.00e+00	1393.00
IUUC-Pva-102306	Pteropus vampyrus	87.08	0.00e+00	2475.00
IUUC-Rno-105354	Rattus norvegicus	87.36	0.00e+00	1736.00
IUUC-Sce-106203	Saccharomyces cerevisiae	31.91	2.00e-24	107.00
IUUC-Sha-106938	Sarcophilus harrisii	94.12	0.00e+00	1917.00
IUUC-Ssc-115810	Sus scrofa	88.61	0.00e+00	2531.00
IUUC-Tgu-117076	Taeniopygia guttata	81.21	0.00e+00	1591.00
IUUC-Tru-117904	Takifugu rubripes	61.52	0.00e+00	1729.00
IUUC-Tsy-119020	Tarsius syrichta	90.73	0.00e+00	1828.00
IUUC-Tni-120813	Tetraodon nigroviridis	64.71	0.00e+00	1866.00
IUUC-Tbe-127494	Tupaia belangeri	73.41	0.00e+00	975.00
IUUC-Ttr-128393	Tursiops truncatus	81.70	0.00e+00	2331.00
IUUC-Vpa-130675	Vicugna pacos	78.44	0.00e+00	731.00
IUUC-Xtr-132829	Xenopus tropicalis	77.93	0.00e+00	2269.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence