iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mvi-060336

Ensembl Protein ID

MVLG_02227T0

UniProt Accession

U5H4I7; U5H4I7_USTV1

Genbank Protein ID

KDE07556.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

AEIJ01000218

Gene Name

MVLG_02227

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MVLG_02227	MVLG_02227T0	MVLG_02227T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-38	128.3	52	88
UBD/Beta-Prp	4.10e-78	261.2	3	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f s+ +l++sG+dD +ikvW+++t ++l
   Q: 52   HDGPVRGISFhSTqPLFCSGGDDYKIKVWNYKTRRCL 88
           99*********878*****************999997 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           + t +++++++++ ++f+p  +lla++  +g+i++w++++g l+ ++++h+++v+ ++f+++++++ +g++D+ ikvw+++t+ c+ tl+gh d+v+
   Q: 3    MLTKFESKSNRVKGIAFHPRLTLLAASLHSGSIQLWNFQMGVLVDRFEEHDGPVRGISFHSTQPLFCSGGDDYKIKVWNYKTRRCLFTLHGHLDYVR 99
           67889999***************************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............................. 166
           s+ f+ +  +++s+s+d+tir+w+++++qc+  +l+gh++ ++c+++hp+++++vs+s D+tvr+Wd+                             
   Q: 100  SVYFHHEHPWILSASDDQTIRIWNWQSRQCIA-ILTGHNHYIMCAQFHPKEDYVVSASMDQTVRVWDIsglrkknttaqplsfeeqiqransgqadl 195
           ********************************.**************************************************************** PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
             +t+ +++   +gh++ v++ +f+++++ +vs+++d+++klw ++ ++   v+t++gh +nv++  f+p++e+++s s+D++ir+Wdl +++ ++t
   Q: 196  fgNTDAVVKYVLEGHDRGVNWATFHPTMPLIVSCGDDRQIKLWRMSDTKAweVDTCRGHFNNVSVALFHPKHELIISDSEDKTIRVWDLSKRTAVQT 292
           *9888888888777********************************777668********************************************* PP
   S: 260  lqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           + ++n++++  ++ +++ n +++g  ds + ++kl++++p
   Q: 293  FRRENDRFWVLTA-HPELNLFAAG-HDSGLIVFKLDRERP 330
           ************9.6655555444.589999999998775 PP

Organism

Microbotryum violaceum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQMLTKFESK SNRVKGIAFH PRLTLLAASL HSGSIQLWNF QMGVLVDRFE EHDGPVRGIS 60
FHSTQPLFCS GGDDYKIKVW NYKTRRCLFT LHGHLDYVRS VYFHHEHPWI LSASDDQTIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACGCTGTC ACCACTACTG GAACCCCCTC CCTGCACCCT CCTCTCCCCC CCTTCCCCCA 60
CTCACCACTC GACCACCTCT CCAGGTTCGA CTAGGTCCGT CGATAAGTGC CGACTGCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	58.59	0.00e+00	1048.00
IUUC-Aml-001758	Ailuropoda melanoleuca	52.61	0.00e+00	1295.00
IUUC-Atr-002493	Amborella trichopoda	59.76	0.00e+00	1053.00
IUUC-Apl-003385	Anas platyrhynchos	49.30	0.00e+00	1011.00
IUUC-Aca-005154	Anolis carolinensis	70.39	4.00e-89	318.00
IUUC-Aly-006020	Arabidopsis lyrata	58.50	0.00e+00	1044.00
IUUC-Ath-007360	Arabidopsis thaliana	58.62	0.00e+00	1050.00
IUUC-Ago-007992	Ashbya gossypii	46.43	0.00e+00	1066.00
IUUC-Acl-008027	Aspergillus clavatus	64.78	0.00e+00	1162.00
IUUC-Afl-008644	Aspergillus flavus	64.75	0.00e+00	1152.00
IUUC-Afu-008964	Aspergillus fumigatus	64.51	0.00e+00	1166.00
IUUC-Ani-009379	Aspergillus nidulans	64.89	0.00e+00	1170.00
IUUC-Ang-009756	Aspergillus niger	64.78	0.00e+00	1168.00
IUUC-Aor-010174	Aspergillus oryzae	64.75	0.00e+00	1152.00
IUUC-Ate-010302	Aspergillus terreus	56.26	0.00e+00	1420.00
IUUC-Ame-011229	Astyanax mexicanus	59.27	0.00e+00	1058.00
IUUC-Bgr-012300	Blumeria graminis	63.05	0.00e+00	1084.00
IUUC-Bta-012524	Bos taurus	52.75	0.00e+00	1284.00
IUUC-Bci-013781	Botrytis cinerea	62.78	0.00e+00	1158.00
IUUC-Bdi-014214	Brachypodium distachyon	50.81	0.00e+00	1222.00
IUUC-Bol-015925	Brassica oleracea	59.07	0.00e+00	1045.00
IUUC-Bra-016978	Brassica rapa	59.00	0.00e+00	1043.00
IUUC-Cel-018115	Caenorhabditis elegans	55.91	0.00e+00	919.00
IUUC-Cja-019107	Callithrix jacchus	51.93	0.00e+00	1271.00
IUUC-Cfa-020675	Canis familiaris	52.49	0.00e+00	1273.00
IUUC-Cpo-021813	Cavia porcellus	52.83	0.00e+00	1301.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	60.26	0.00e+00	1073.00
IUUC-Csa-023523	Chlorocebus sabaeus	52.91	0.00e+00	1301.00
IUUC-Cho-024704	Choloepus hoffmanni	53.92	0.00e+00	787.00
IUUC-Cin-025572	Ciona intestinalis	50.32	0.00e+00	1220.00
IUUC-Csv-025864	Ciona savignyi	56.04	0.00e+00	969.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	65.24	0.00e+00	1187.00
IUUC-Cne-027053	Cryptococcus neoformans	73.76	0.00e+00	1332.00
IUUC-Cme-027222	Cyanidioschyzon merolae	43.37	1.00e-148	519.00
IUUC-Dre-027421	Danio rerio	51.51	0.00e+00	1263.00
IUUC-Dno-029303	Dasypus novemcinctus	52.78	0.00e+00	1300.00
IUUC-Dor-030290	Dipodomys ordii	48.94	1.00e-155	543.00
IUUC-Dse-031543	Dothistroma septosporum	55.46	0.00e+00	1316.00
IUUC-Dme-031945	Drosophila melanogaster	56.49	0.00e+00	985.00
IUUC-Ete-032873	Echinops telfairi	56.74	0.00e+00	994.00
IUUC-Eca-033773	Equus caballus	52.30	0.00e+00	1267.00
IUUC-Eeu-034874	Erinaceus europaeus	41.12	3.00e-180	624.00
IUUC-Fca-035739	Felis catus	59.43	0.00e+00	1050.00
IUUC-Fal-037263	Ficedula albicollis	49.31	0.00e+00	1159.00
IUUC-Fox-037738	Fusarium oxysporum	56.80	0.00e+00	1417.00
IUUC-Fso-038153	Fusarium solani	65.25	0.00e+00	1187.00
IUUC-Gmo-039602	Gadus morhua	49.43	0.00e+00	1176.00
IUUC-Ggr-039931	Gaeumannomyces graminis	63.69	0.00e+00	1160.00
IUUC-Gga-040590	Gallus gallus	53.04	0.00e+00	1308.00
IUUC-Gac-041318	Gasterosteus aculeatus	52.24	0.00e+00	1273.00
IUUC-Gma-043894	Glycine max	59.81	0.00e+00	1067.00
IUUC-Ggo-045029	Gorilla gorilla	52.53	0.00e+00	1293.00
IUUC-Hsa-046078	Homo sapiens	52.45	0.00e+00	1290.00
IUUC-Hvu-047556	Hordeum vulgare	50.36	0.00e+00	1228.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	44.62	0.00e+00	712.00
IUUC-Kpa-049256	Komagataella pastoris	47.95	0.00e+00	1165.00
IUUC-Lch-049706	Latimeria chalumnae	52.71	0.00e+00	1278.00
IUUC-Lpe-051316	Leersia perrieri	58.95	0.00e+00	1053.00
IUUC-Loc-051867	Lepisosteus oculatus	47.77	0.00e+00	780.00
IUUC-Lma-053138	Leptosphaeria maculans	63.10	0.00e+00	1170.00
IUUC-Laf-053510	Loxodonta africana	53.60	0.00e+00	1303.00
IUUC-Mcc-055836	Macaca mulatta	52.53	0.00e+00	1295.00
IUUC-Meu-056238	Macropus eugenii	55.75	0.00e+00	768.00
IUUC-Mor-057172	Magnaporthe oryzae	63.73	0.00e+00	1162.00
IUUC-Mpo-057300	Magnaporthe poae	63.42	0.00e+00	1162.00
IUUC-Mtr-058248	Medicago truncatula	58.84	0.00e+00	1058.00
IUUC-Mla-059019	Melampsora laricipopulina	82.83	0.00e+00	1529.00
IUUC-Mga-059499	Meleagris gallopavo	52.87	0.00e+00	1303.00
IUUC-Mmr-061102	Microcebus murinus	52.52	0.00e+00	1284.00
IUUC-Mdo-062594	Monodelphis domestica	52.83	0.00e+00	1296.00
IUUC-Mmu-063736	Mus musculus	52.37	0.00e+00	1290.00
IUUC-Mac-065398	Musa acuminata	47.77	0.00e+00	1120.00
IUUC-Mpu-066701	Mustela putorius furo	53.06	0.00e+00	1302.00
IUUC-Mlu-067392	Myotis lucifugus	52.99	0.00e+00	1295.00
IUUC-Nfi-068270	Neosartorya fischeri	64.66	0.00e+00	1167.00
IUUC-Ncr-068892	Neurospora crassa	63.28	0.00e+00	1181.00
IUUC-Nle-069634	Nomascus leucogenys	62.99	0.00e+00	910.00
IUUC-Opr-070952	Ochotona princeps	40.48	9.00e-178	616.00
IUUC-Ont-072488	Oreochromis niloticus	52.59	0.00e+00	1270.00
IUUC-Ocu-074211	Oryctolagus cuniculus	52.91	0.00e+00	1301.00
IUUC-Oba-075761	Oryza barthii	58.71	0.00e+00	1053.00
IUUC-Obr-076429	Oryza brachyantha	58.35	0.00e+00	1047.00
IUUC-Ogl-077364	Oryza glaberrima	58.71	0.00e+00	1053.00
IUUC-Ogu-078257	Oryza glumaepatula	58.71	0.00e+00	1051.00
IUUC-Oin-080029	Oryza indica	58.95	0.00e+00	1056.00
IUUC-Olo-080466	Oryza longistaminata	59.35	0.00e+00	1052.00
IUUC-Ome-081993	Oryza meridionalis	61.02	0.00e+00	1012.00
IUUC-Oni-082874	Oryza nivara	58.52	0.00e+00	1052.00
IUUC-Opu-083885	Oryza punctata	58.95	0.00e+00	1049.00
IUUC-Oru-084274	Oryza rufipogon	58.59	0.00e+00	1051.00
IUUC-Osa-085565	Oryza sativa	58.59	0.00e+00	1051.00
IUUC-Ola-086921	Oryzias latipes	51.68	0.00e+00	1258.00
IUUC-Olu-087639	Ostreococcus lucimarinus	52.82	0.00e+00	1269.00
IUUC-Oga-087991	Otolemur garnettii	50.69	0.00e+00	1214.00
IUUC-Oar-089590	Ovis aries	52.99	0.00e+00	1303.00
IUUC-Ptr-090808	Pan troglodytes	52.45	0.00e+00	1291.00
IUUC-Pan-092475	Papio anubis	52.47	0.00e+00	1287.00
IUUC-Psi-093044	Pelodiscus sinensis	53.05	0.00e+00	863.00
IUUC-Pno-094839	Phaeosphaeria nodorum	63.70	0.00e+00	1122.00
IUUC-Ppa-095254	Physcomitrella patens	62.30	0.00e+00	1103.00
IUUC-Pfo-097493	Poecilia formosa	52.58	0.00e+00	1268.00
IUUC-Pab-098497	Pongo abelii	52.83	0.00e+00	1300.00
IUUC-Pop-099992	Populus trichocarpa	59.52	0.00e+00	1053.00
IUUC-Pca-100413	Procavia capensis	56.63	0.00e+00	663.00
IUUC-Ppe-101899	Prunus persica	60.36	0.00e+00	1070.00
IUUC-Pva-102126	Pteropus vampyrus	50.84	0.00e+00	1228.00
IUUC-Pgr-103376	Puccinia graminis	73.35	0.00e+00	1857.00
IUUC-Ptt-103978	Puccinia triticina	65.66	0.00e+00	1590.00
IUUC-Pte-104126	Pyrenophora teres	63.43	0.00e+00	1126.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	55.26	0.00e+00	783.00
IUUC-Rno-105428	Rattus norvegicus	52.99	0.00e+00	1303.00
IUUC-Sce-106464	Saccharomyces cerevisiae	53.75	0.00e+00	909.00
IUUC-Sha-107301	Sarcophilus harrisii	52.58	0.00e+00	1278.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	50.24	0.00e+00	1238.00
IUUC-Spo-108217	Schizosaccharomyces pombe	51.15	0.00e+00	1284.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	62.78	0.00e+00	1157.00
IUUC-Smo-109582	Selaginella moellendorffii	60.02	0.00e+00	1093.00
IUUC-Sit-109697	Setaria italica	59.09	0.00e+00	1051.00
IUUC-Sly-111759	Solanum lycopersicum	52.03	0.00e+00	1253.00
IUUC-Stu-112564	Solanum tuberosum	51.86	0.00e+00	1254.00
IUUC-Sar-113313	Sorex araneus	40.20	1.00e-174	605.00
IUUC-Sbi-114388	Sorghum bicolor	58.83	0.00e+00	1052.00
IUUC-Sre-115209	Sporisorium reilianum	73.32	0.00e+00	1330.00
IUUC-Ssc-115933	Sus scrofa	52.99	0.00e+00	1303.00
IUUC-Tgu-117109	Taeniopygia guttata	46.27	1.00e-96	345.00
IUUC-Tru-117772	Takifugu rubripes	52.60	0.00e+00	1259.00
IUUC-Tsy-119105	Tarsius syrichta	50.10	0.00e+00	996.00
IUUC-Tni-120556	Tetraodon nigroviridis	39.11	0.00e+00	746.00
IUUC-Tca-121545	Theobroma cacao	60.19	0.00e+00	1073.00
IUUC-Tre-121951	Trichoderma reesei	63.26	0.00e+00	1174.00
IUUC-Tvi-122359	Trichoderma virens	64.76	0.00e+00	1180.00
IUUC-Tae-123688	Triticum aestivum	50.12	0.00e+00	1228.00
IUUC-Tur-126016	Triticum urartu	49.57	0.00e+00	1110.00
IUUC-Tme-127170	Tuber melanosporum	56.28	0.00e+00	1420.00
IUUC-Tbe-127882	Tupaia belangeri	47.12	4.00e-145	507.00
IUUC-Ttr-128217	Tursiops truncatus	51.00	0.00e+00	1232.00
IUUC-Uma-129337	Ustilago maydis	73.08	0.00e+00	1323.00
IUUC-Vda-129828	Verticillium dahliae	62.54	0.00e+00	1125.00
IUUC-Vpa-130537	Vicugna pacos	51.88	0.00e+00	1259.00
IUUC-Vvi-130958	Vitis vinifera	59.52	0.00e+00	1061.00
IUUC-Xtr-132857	Xenopus tropicalis	50.08	0.00e+00	1169.00
IUUC-Xma-133138	Xiphophorus maculatus	52.58	0.00e+00	1269.00
IUUC-Yli-134399	Yarrowia lipolytica	55.80	0.00e+00	961.00
IUUC-Zma-135612	Zea mays	50.49	0.00e+00	1216.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence