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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046841
Ensembl Protein ID ENSP00000364798.4
UniProt Accession Q9NUA8; O75066; Q5TFU5; Q8N1R1; ZBT40_HUMAN
Genbank Protein ID BAA32323.2; BAC04518.1; CAI22040.1
Protein Name Zinc finger and BTB domain-containing protein 40
Genbank Nucleotide ID AB007947; AK095273; AL035703
Gene Name ZBTB40; KIAA0478
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000184677.16 ENST00000375647.4 ENSP00000364798.4
ENSG00000184677.16 ENST00000374651.8 ENSP00000363782.4
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Disease-associated Variation
GWASdbGWAS CentralOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtBioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 2.90e-08 35.6 24 85
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgklde 67
           +D+++ +g  +f+ahk+vLaa+S  F+ l+++       ++++ i+   v+pe f  ll+ +Ytgkl+ 
   Q: 24   CDCTISIGTIYFRAHKLVLAAASLLFKTLLDN-------TDTISIDAsvVSPEEFALLLEMMYTGKLPV 85
           8*****************************43.......8899999558*****************986 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Belongs to the krueppel C2H2-type zinc-finger protein family.
 Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein Sequence
(Fasta)
MELPNYSRQL LQQLYTLCKE QQFCDCTISI GTIYFRAHKL VLAAASLLFK TLLDNTDTIS 60
IDASVVSPEE FALLLEMMYT GKLPVGKHNF SKIISLADSL QMFDVAVSCK NLLTSLVNCS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046841|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATACCCATT GCGCGCCGGC CTCAAGATGG CCGCCTTCTG GCGTCTCCGG CGCTGTTGAA 60
TGGCGAAAGC TTTATTGTTC CCTTCGGGCA GGAGTGTTCG TGTCCTCTAT GGCGCTGTCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046841|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR011029--DEATH-like_dom
IPR011333--SKP1/BTB/POZ
IPR030404--ZBTB40
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0030282--P:bone mineralization
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:9923
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001920 Ailuropoda melanoleuca 84.46 0.00e+00 2112.00
IUUC-Apl-003605 Anas platyrhynchos 43.31 1.00e-146 513.00
IUUC-Ame-011397 Astyanax mexicanus 35.60 5.00e-167 582.00
IUUC-Bta-012624 Bos taurus 83.05 0.00e+00 2032.00
IUUC-Cja-018947 Callithrix jacchus 93.64 0.00e+00 2333.00
IUUC-Cfa-020834 Canis familiaris 86.08 0.00e+00 2129.00
IUUC-Cpo-022231 Cavia porcellus 82.98 0.00e+00 1978.00
IUUC-Csa-023812 Chlorocebus sabaeus 96.37 0.00e+00 2416.00
IUUC-Cho-024798 Choloepus hoffmanni 79.15 0.00e+00 1369.00
IUUC-Dre-028535 Danio rerio 37.64 5.00e-158 551.00
IUUC-Dno-029544 Dasypus novemcinctus 86.80 0.00e+00 2145.00
IUUC-Ete-032390 Echinops telfairi 76.20 0.00e+00 1785.00
IUUC-Eca-033930 Equus caballus 82.61 0.00e+00 2004.00
IUUC-Fca-035364 Felis catus 77.63 0.00e+00 1374.00
IUUC-Gga-040492 Gallus gallus 53.10 0.00e+00 703.00
IUUC-Ggo-045476 Gorilla gorilla 98.47 0.00e+00 2447.00
IUUC-Lch-050586 Latimeria chalumnae 47.88 0.00e+00 1096.00
IUUC-Loc-052801 Lepisosteus oculatus 44.99 0.00e+00 805.00
IUUC-Laf-053711 Loxodonta africana 86.10 0.00e+00 2165.00
IUUC-Mcc-055818 Macaca mulatta 96.05 0.00e+00 2409.00
IUUC-Mga-059901 Meleagris gallopavo 62.33 0.00e+00 1422.00
IUUC-Mmr-060838 Microcebus murinus 87.34 0.00e+00 2159.00
IUUC-Mdo-061850 Monodelphis domestica 68.09 0.00e+00 1681.00
IUUC-Mmu-063124 Mus musculus 77.30 0.00e+00 1869.00
IUUC-Mpu-065753 Mustela putorius furo 83.74 0.00e+00 2003.00
IUUC-Mlu-066935 Myotis lucifugus 82.93 0.00e+00 2049.00
IUUC-Nle-070124 Nomascus leucogenys 97.50 0.00e+00 2440.00
IUUC-Opr-070923 Ochotona princeps 84.20 0.00e+00 1448.00
IUUC-Ont-071320 Oreochromis niloticus 49.70 3.00e-129 456.00
IUUC-Oan-073611 Ornithorhynchus anatinus 66.56 0.00e+00 1602.00
IUUC-Ocu-074805 Oryctolagus cuniculus 82.85 0.00e+00 1961.00
IUUC-Ola-087539 Oryzias latipes 67.52 3.00e-33 133.00
IUUC-Oga-088828 Otolemur garnettii 85.76 0.00e+00 2174.00
IUUC-Oar-089430 Ovis aries 82.32 0.00e+00 2027.00
IUUC-Ptr-090587 Pan troglodytes 98.55 0.00e+00 2468.00
IUUC-Pan-091889 Papio anubis 93.80 0.00e+00 1682.00
IUUC-Pab-098090 Pongo abelii 97.90 0.00e+00 2412.00
IUUC-Rno-104899 Rattus norvegicus 77.37 0.00e+00 1882.00
IUUC-Sha-106799 Sarcophilus harrisii 63.11 0.00e+00 1465.00
IUUC-Sar-113563 Sorex araneus 71.13 0.00e+00 1039.00
IUUC-Ssc-115845 Sus scrofa 80.96 0.00e+00 1967.00
IUUC-Tru-117975 Takifugu rubripes 53.27 8.00e-134 471.00
IUUC-Tsy-119438 Tarsius syrichta 76.87 0.00e+00 1278.00
IUUC-Ttr-128872 Tursiops truncatus 82.21 0.00e+00 1992.00
IUUC-Vpa-130652 Vicugna pacos 75.50 0.00e+00 1361.00
Created Date 25-Jun-2017

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