iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118720

Ensembl Protein ID

ENSTRUP00000029320.1

UniProt Accession

H2TXB1; H2TXB1_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000011601.1	ENSTRUT00000029437.1	ENSTRUP00000029320.1
ENSTRUG00000011601.1	ENSTRUT00000029438.1	ENSTRUP00000029321.1
ENSTRUG00000011601.1	ENSTRUT00000029439.1	ENSTRUP00000029322.1
ENSTRUG00000011601.1	ENSTRUT00000029440.1	ENSTRUP00000029323.1
ENSTRUG00000011601.1	ENSTRUT00000029441.1	ENSTRUP00000029324.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	9.90e-39	134.1	199	373

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek....edekefcqklvepe.....ak.g.. 77
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++++++ +++ + k+++++++++++k    e+e++++ kl+++e     +k g  
   Q: 199  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKSLYTMMKSGAERDALKRRWRWQQTQQNKeeewEKEWNELLKLASSEprthlSKnGnt 287
           6899********************************************************9999999**********988766444488 PP
   S: 78   ...............eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYdaLval 138
                          ee+h+f+La++L+rpi+vv++++l++         ++gg +lpl++p+++ +++p+vL+Y+++H++aLv++
   Q: 288  sggvdnsedpvyeslEEFHVFVLAHVLRRPIVVVADTMLRDsggeafapiPFGGLYLPLEVPPSRcHCSPLVLAYDQAHFSALVSM 373
           889********************************************************************************986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

RLASTKATAA PWAAHAHDHM TLDMDAVLSD FVRSTGAEPG LARDLLEGKN WDLNAALNDY 60
EELRQVHTAN LPQVFNEGRY CRQPETRDTP THVSKIDRPC AQKQEDNAQE KRLSRGISHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCTGGCGT CCACCAAGGC CACCGCTGCA CCTTGGGCAG CGCACGCACA TGATCACATG 60
ACTCTGGACA TGGACGCGGT CCTGTCAGAC TTTGTTCGGT CCACGGGGGC TGAACCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR009060--UBA-like
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

SMART

SM00259--ZnF_A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001551	Ailuropoda melanoleuca	78.97	0.00e+00	880.00
IUUC-Apl-003825	Anas platyrhynchos	70.81	0.00e+00	1202.00
IUUC-Aca-004392	Anolis carolinensis	74.26	0.00e+00	1217.00
IUUC-Ame-011052	Astyanax mexicanus	80.26	0.00e+00	1323.00
IUUC-Bta-013296	Bos taurus	64.16	0.00e+00	968.00
IUUC-Bol-015805	Brassica oleracea	35.19	1.40e+00	28.10
IUUC-Cja-019141	Callithrix jacchus	77.55	0.00e+00	897.00
IUUC-Cfa-020447	Canis familiaris	79.73	0.00e+00	930.00
IUUC-Cpo-022059	Cavia porcellus	86.30	0.00e+00	824.00
IUUC-Csa-023263	Chlorocebus sabaeus	79.85	0.00e+00	939.00
IUUC-Cho-024611	Choloepus hoffmanni	77.46	9.00e-150	524.00
IUUC-Dre-028617	Danio rerio	78.25	0.00e+00	1321.00
IUUC-Dno-029121	Dasypus novemcinctus	78.77	0.00e+00	933.00
IUUC-Ete-033068	Echinops telfairi	73.99	0.00e+00	840.00
IUUC-Eca-034413	Equus caballus	79.45	0.00e+00	892.00
IUUC-Eeu-034670	Erinaceus europaeus	53.03	0.00e+00	770.00
IUUC-Fca-036487	Felis catus	76.63	0.00e+00	856.00
IUUC-Fal-037145	Ficedula albicollis	73.69	0.00e+00	1201.00
IUUC-Gmo-038786	Gadus morhua	74.36	0.00e+00	1199.00
IUUC-Gga-040512	Gallus gallus	73.44	0.00e+00	1229.00
IUUC-Gac-041599	Gasterosteus aculeatus	90.83	0.00e+00	1418.00
IUUC-Ggo-044819	Gorilla gorilla	65.90	0.00e+00	995.00
IUUC-Hsa-046781	Homo sapiens	67.38	0.00e+00	1061.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	52.52	0.00e+00	790.00
IUUC-Lch-050666	Latimeria chalumnae	75.42	0.00e+00	1196.00
IUUC-Loc-052841	Lepisosteus oculatus	88.45	0.00e+00	893.00
IUUC-Laf-053437	Loxodonta africana	77.56	0.00e+00	931.00
IUUC-Mcc-055353	Macaca mulatta	67.89	0.00e+00	1056.00
IUUC-Meu-056510	Macropus eugenii	61.48	2.00e-103	370.00
IUUC-Mga-059741	Meleagris gallopavo	70.44	0.00e+00	1154.00
IUUC-Mmr-061437	Microcebus murinus	80.48	0.00e+00	998.00
IUUC-Mdo-061907	Monodelphis domestica	77.30	0.00e+00	1220.00
IUUC-Mmu-064074	Mus musculus	77.57	0.00e+00	950.00
IUUC-Mpu-066004	Mustela putorius furo	78.00	0.00e+00	875.00
IUUC-Mlu-068039	Myotis lucifugus	52.49	0.00e+00	780.00
IUUC-Nle-069182	Nomascus leucogenys	75.10	0.00e+00	944.00
IUUC-Opr-070701	Ochotona princeps	67.25	0.00e+00	749.00
IUUC-Ont-072431	Oreochromis niloticus	89.63	0.00e+00	1479.00
IUUC-Oan-073235	Ornithorhynchus anatinus	79.48	0.00e+00	794.00
IUUC-Ocu-073935	Oryctolagus cuniculus	79.49	0.00e+00	873.00
IUUC-Ola-087026	Oryzias latipes	88.32	0.00e+00	1495.00
IUUC-Oga-088249	Otolemur garnettii	78.71	0.00e+00	979.00
IUUC-Oar-089476	Ovis aries	65.64	0.00e+00	1031.00
IUUC-Ptr-090548	Pan troglodytes	78.98	0.00e+00	853.00
IUUC-Pan-092616	Papio anubis	80.85	0.00e+00	939.00
IUUC-Psi-093126	Pelodiscus sinensis	73.42	0.00e+00	1211.00
IUUC-Pfo-096785	Poecilia formosa	86.89	0.00e+00	1442.00
IUUC-Pab-098336	Pongo abelii	68.87	0.00e+00	956.00
IUUC-Pca-100206	Procavia capensis	77.78	3.00e-150	525.00
IUUC-Rno-105546	Rattus norvegicus	53.49	0.00e+00	756.00
IUUC-Sha-106617	Sarcophilus harrisii	78.79	0.00e+00	843.00
IUUC-Sar-113562	Sorex araneus	47.78	2.00e-172	599.00
IUUC-Ssc-115415	Sus scrofa	78.34	0.00e+00	866.00
IUUC-Tgu-117218	Taeniopygia guttata	78.16	0.00e+00	976.00
IUUC-Tsy-119343	Tarsius syrichta	60.79	0.00e+00	716.00
IUUC-Tni-120795	Tetraodon nigroviridis	96.08	0.00e+00	914.00
IUUC-Ttr-128692	Tursiops truncatus	49.89	0.00e+00	717.00
IUUC-Xtr-132158	Xenopus tropicalis	70.85	0.00e+00	1214.00
IUUC-Xma-133941	Xiphophorus maculatus	91.05	0.00e+00	1425.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence