iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000001318.1	ENSONIT00000001665.1	ENSONIP00000001666.1
ENSONIG00000001318.1	ENSONIT00000001666.1	ENSONIP00000001667.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.20e-76	256.2	40	500

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +G+kN+g tCY+NS+LQ+L+++pe+re l++  + +l   ++k++ +     +  +lq+lf++l+  ++++ s+  l++++++ ++e  
   Q: 40   CGIKNQGGTCYLNSLLQTLLFTPEFREELFSLVPDELGCLEDKDKPEakvrVIPLELQRLFAHLLLVDQQSASTAGLTDSFGWNSSE-- 126
           7******************************66666654443222223444899****************************99987.. PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           g++q+D+qE+ ++l+++le +l                            ++++++i++l++g++ ++i+c+ec+nvs+r+e+fldl++
   Q: 127  GTNQHDVQELNRILFSALEHSL--------------------------VGTSGSTFIHRLYHGTIVNSIVCKECGNVSQRQEDFLDLTV 189
           **********************..........................7899************************************* PP
   S: 175  pvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
            v g +     sl+d+L ++f++ee +eg+n y c +c+++++a k+ kl+klP+++++ L Rfsf+ +++ r k + +++fpl+++l+
   Q: 190  CVCGLS-----SLEDALwNMFVAEELFEGNNLYRCAQCDRLVTAAKSAKLRKLPPFMTMSLLRFSFDFAKCERYKETGRYSFPLTINLR 273
           ******.....9*****99********************************************************************** PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.................................................. 301
           pfc++ + + +++++YeL++v++H+G++ +GHY++y+k+                                                  
   Q: 274  PFCEQGDGD-DSDYSYELFSVIIHKGGCYGGHYHVYIKDvdklgrweppeedckpktqkkakvelkevlepklqeddplsivttiiaqe 361
           *****6655.56***************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 362  ssksvlldqlgqklmdkigsswnkkfrkqygpickflqshndvfmmvsngtrvalkanppspatelpspaeltsnsdpspapvsgasep 450
           ************************************************************************************99999 PP
   S: 302  ............ekgkWllfdDskVtevkeeevleetg..staYvlfYkr 337
                       e  +W+ ++Ds+Vt+++e++++++ +  ++aY+lfY++
   Q: 451  qlalnqkpepepEGSHWFDLNDSTVTSIRESDIEKQFQgkESAYMLFYRK 500
           9999988887754555*******************9889*********98 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MFGNLFEEEE EEGFSSTSSK GRVSKIGDEP PPPRGRSNLC GIKNQGGTCY LNSLLQTLLF 60
TPEFREELFS LVPDELGCLE DKDKPEAKVR VIPLELQRLF AHLLLVDQQS ASTAGLTDSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAACAT GGCTGCTCAC TGTTCAACGA CGGTATTTTT ATTTACGTTT CGTTTGTTTT 60
CTGCTTTACG ACAAACAGAA GAAGAAATGG CTTATTTTGG TAGGGATTCT GAGTAAAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	47.94	0.00e+00	1027.00
IUUC-Apl-004105	Anas platyrhynchos	48.86	0.00e+00	1115.00
IUUC-Aca-004715	Anolis carolinensis	48.25	0.00e+00	1081.00
IUUC-Ame-011073	Astyanax mexicanus	58.24	0.00e+00	1306.00
IUUC-Bta-012487	Bos taurus	47.88	0.00e+00	1071.00
IUUC-Cja-018937	Callithrix jacchus	47.70	0.00e+00	1075.00
IUUC-Cfa-020645	Canis familiaris	38.08	2.00e-150	526.00
IUUC-Cpo-022160	Cavia porcellus	57.29	0.00e+00	735.00
IUUC-Csa-023078	Chlorocebus sabaeus	47.13	0.00e+00	1074.00
IUUC-Cho-025013	Choloepus hoffmanni	75.00	3.00e-105	376.00
IUUC-Csv-026193	Ciona savignyi	55.84	2.00e-57	215.00
IUUC-Dre-027416	Danio rerio	63.80	0.00e+00	1510.00
IUUC-Dno-029639	Dasypus novemcinctus	42.93	0.00e+00	837.00
IUUC-Dor-030624	Dipodomys ordii	67.53	1.00e-112	401.00
IUUC-Ete-032626	Echinops telfairi	35.05	2.00e-101	363.00
IUUC-Eca-034208	Equus caballus	47.86	0.00e+00	1082.00
IUUC-Fca-036006	Felis catus	65.92	4.00e-144	504.00
IUUC-Fal-036925	Ficedula albicollis	48.55	0.00e+00	1059.00
IUUC-Gmo-038597	Gadus morhua	68.39	0.00e+00	1454.00
IUUC-Gga-041171	Gallus gallus	48.27	0.00e+00	1093.00
IUUC-Gac-041362	Gasterosteus aculeatus	79.41	0.00e+00	1724.00
IUUC-Ggo-045069	Gorilla gorilla	46.52	0.00e+00	955.00
IUUC-Hsa-046715	Homo sapiens	47.79	0.00e+00	1065.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	46.14	0.00e+00	1027.00
IUUC-Lch-050182	Latimeria chalumnae	47.16	0.00e+00	1007.00
IUUC-Loc-052705	Lepisosteus oculatus	60.25	0.00e+00	1456.00
IUUC-Laf-054132	Loxodonta africana	46.36	0.00e+00	1065.00
IUUC-Mcc-055734	Macaca mulatta	47.82	0.00e+00	1076.00
IUUC-Meu-056135	Macropus eugenii	75.76	8.00e-100	358.00
IUUC-Mga-060092	Meleagris gallopavo	47.88	0.00e+00	1068.00
IUUC-Mmr-061546	Microcebus murinus	45.84	0.00e+00	989.00
IUUC-Mdo-061935	Monodelphis domestica	46.92	0.00e+00	1076.00
IUUC-Mmu-063630	Mus musculus	47.07	0.00e+00	1068.00
IUUC-Mpu-066579	Mustela putorius furo	46.96	0.00e+00	1095.00
IUUC-Mlu-068034	Myotis lucifugus	46.89	0.00e+00	1038.00
IUUC-Nle-069082	Nomascus leucogenys	42.51	0.00e+00	807.00
IUUC-Opr-070953	Ochotona princeps	37.75	9.00e-123	435.00
IUUC-Oan-073339	Ornithorhynchus anatinus	48.37	0.00e+00	1086.00
IUUC-Ocu-073760	Oryctolagus cuniculus	47.90	0.00e+00	1085.00
IUUC-Ola-087015	Oryzias latipes	76.16	0.00e+00	1632.00
IUUC-Oga-088960	Otolemur garnettii	47.27	0.00e+00	1073.00
IUUC-Oar-089853	Ovis aries	47.69	0.00e+00	1074.00
IUUC-Ptr-091093	Pan troglodytes	47.71	0.00e+00	1058.00
IUUC-Pan-091962	Papio anubis	47.08	0.00e+00	1062.00
IUUC-Psi-093691	Pelodiscus sinensis	48.81	0.00e+00	1121.00
IUUC-Pma-094428	Petromyzon marinus	61.15	6.00e-85	307.00
IUUC-Pfo-096983	Poecilia formosa	79.52	0.00e+00	1795.00
IUUC-Pab-097860	Pongo abelii	46.42	0.00e+00	971.00
IUUC-Pca-100514	Procavia capensis	51.18	5.00e-114	406.00
IUUC-Pva-102771	Pteropus vampyrus	46.90	0.00e+00	1003.00
IUUC-Rno-105405	Rattus norvegicus	47.22	0.00e+00	1071.00
IUUC-Sha-107376	Sarcophilus harrisii	46.69	0.00e+00	1028.00
IUUC-Ssc-115819	Sus scrofa	39.96	1.00e-179	623.00
IUUC-Tgu-117262	Taeniopygia guttata	48.17	0.00e+00	1096.00
IUUC-Tru-117601	Takifugu rubripes	74.40	0.00e+00	1833.00
IUUC-Tsy-118996	Tarsius syrichta	40.34	0.00e+00	751.00
IUUC-Tni-120682	Tetraodon nigroviridis	68.29	0.00e+00	813.00
IUUC-Tbe-127616	Tupaia belangeri	35.99	7.00e-175	608.00
IUUC-Ttr-129075	Tursiops truncatus	59.08	0.00e+00	662.00
IUUC-Vpa-130108	Vicugna pacos	47.72	0.00e+00	976.00
IUUC-Xtr-132623	Xenopus tropicalis	45.89	0.00e+00	1025.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence