iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002374.3	ENSXETT00000065527.1	ENSXETP00000058805.1
ENSXETG00000002374.3	ENSXETT00000005057.2	ENSXETP00000005057.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.20e-109	365.7	1	377

Active Site

Position(s)	Description	Evidence
127	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 48   vDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclnarvp 136
           +D dt++vsnlnrqFLf++++vg+sKA+va+e++ +++p  n++a+++si++++++++Ffk+f++V++aldn +ar++vnr+cl+a +p
   Q: 1    IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIP 89
           7**************************************************************************************** PP
   S: 137  liesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.vlfnklleeeageeevlekldseekeegkdkvks 224
           liesgt G+lGqv+v+ kg+tecy+c+++p+qkt+P+ct+++tp+++ h+i+wa +lfn+l++ee++++ev++++  +++e+++d++++
   Q: 90   LIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAkYLFNQLFGEEDADQEVAPDI--ADPEAAWDPTQA 176
           *************************************************************************76..7*********** PP
   S: 225  elksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv...................sfcsnaealqvp.ekvekd 292
           ++++++++ + +++++++k++ak+t ++ ik + k f++di +  +++ ++                   + ++ +e++++    ++kd
   Q: 177  AERANASNVDGDIKRVSTKQWAKSTGYDpIKLFNKLFRDDIKYLLTMDRLWrkrkppvplewsslhnkdyKTKNCSETQNESsLQGLKD 265
           ****************************************************************9999994444444444431468999 PP
   S: 293  eevvkasaplylllralerfekkkgrk..pgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGl 379
           ++v++++++ +l+ +++e+++++  +k   +el ++kdd+ a+d+vtaaanlr++ +++++  +++++k++agniipaiattnav++Gl
   Q: 266  QKVLDVTSCAQLFSKSVETLREQLREKgnGAELVWDKDDPPAMDFVTAAANLRMHIFSMNM-KSRFDVKSMAGNIIPAIATTNAVISGL 353
           *******996666666666665544431134899***************************.*************************** PP
   S: 380  aaqEviKvvsgkfeplknfflfda 403
           +++E +K++sg  e+++++fl+++
   Q: 354  IVLEGLKILSGNTEQCRTVFLNKQ 377
           ********************9965 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

IDLDTIDVSN LNRQFLFQKK HVGRSKAQVA KESVLQFCPE ANITAYHDSI MNPDYNVEFF 60
KQFTMVMNAL DNNAARNHVN RMCLAAGIPL IESGTAGYLG QVTVVKKGVT ECYECQPKPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGACCTGG ATACTATTGA TGTCAGCAAT CTCAACAGAC AGTTTCTTTT TCAAAAAAAG 60
CATGTTGGAA GATCAAAGGC CCAGGTAATT TATGTGGGGA GAAAATGTGT AACATGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR019572--UBA_E1_Cys
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C
PF10585--UBA_e1_thiolCys

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	38.67	1.00e-95	343.00
IUUC-Aml-001662	Ailuropoda melanoleuca	75.50	0.00e+00	912.00
IUUC-Atr-002636	Amborella trichopoda	37.08	5.00e-98	351.00
IUUC-Apl-003369	Anas platyrhynchos	76.29	0.00e+00	855.00
IUUC-Aca-004490	Anolis carolinensis	76.42	0.00e+00	757.00
IUUC-Aly-006359	Arabidopsis lyrata	38.70	1.00e-87	317.00
IUUC-Ath-007667	Arabidopsis thaliana	39.49	1.00e-90	327.00
IUUC-Ago-007844	Ashbya gossypii	39.28	2.00e-66	246.00
IUUC-Acl-008270	Aspergillus clavatus	38.95	4.00e-89	322.00
IUUC-Afl-008674	Aspergillus flavus	39.96	7.00e-94	337.00
IUUC-Afu-008883	Aspergillus fumigatus	42.16	7.00e-91	328.00
IUUC-Ani-009500	Aspergillus nidulans	44.60	3.00e-96	345.00
IUUC-Ang-009535	Aspergillus niger	43.58	3.00e-92	332.00
IUUC-Aor-010223	Aspergillus oryzae	39.92	1.00e-94	340.00
IUUC-Ate-010282	Aspergillus terreus	41.78	3.00e-74	272.00
IUUC-Ame-011736	Astyanax mexicanus	70.97	0.00e+00	837.00
IUUC-Bgr-012166	Blumeria graminis	42.41	5.00e-83	301.00
IUUC-Bta-012589	Bos taurus	75.13	0.00e+00	912.00
IUUC-Bci-013802	Botrytis cinerea	40.73	6.00e-87	315.00
IUUC-Bdi-014697	Brachypodium distachyon	37.63	3.00e-97	348.00
IUUC-Bol-016315	Brassica oleracea	37.26	3.00e-95	342.00
IUUC-Bra-017009	Brassica rapa	38.06	3.00e-95	342.00
IUUC-Cel-018708	Caenorhabditis elegans	41.86	1.00e-117	416.00
IUUC-Cja-019120	Callithrix jacchus	75.63	0.00e+00	885.00
IUUC-Cfa-021061	Canis familiaris	75.29	0.00e+00	912.00
IUUC-Cpo-021842	Cavia porcellus	75.46	0.00e+00	879.00
IUUC-Csa-024104	Chlorocebus sabaeus	75.67	0.00e+00	869.00
IUUC-Cho-024332	Choloepus hoffmanni	73.88	0.00e+00	713.00
IUUC-Cin-025363	Ciona intestinalis	55.25	5.00e-167	580.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.17	5.00e-81	295.00
IUUC-Cne-026888	Cryptococcus neoformans	39.83	4.00e-63	235.00
IUUC-Cme-027315	Cyanidioschyzon merolae	30.02	1.00e-49	191.00
IUUC-Dre-028420	Danio rerio	70.42	0.00e+00	792.00
IUUC-Dno-030041	Dasypus novemcinctus	75.33	0.00e+00	880.00
IUUC-Dor-031039	Dipodomys ordii	59.11	4.00e-128	451.00
IUUC-Dse-031504	Dothistroma septosporum	44.93	6.00e-85	308.00
IUUC-Dme-031771	Drosophila melanogaster	45.29	3.00e-124	438.00
IUUC-Ete-033037	Echinops telfairi	70.12	0.00e+00	777.00
IUUC-Eca-033774	Equus caballus	75.46	0.00e+00	919.00
IUUC-Eeu-035074	Erinaceus europaeus	71.95	0.00e+00	705.00
IUUC-Fca-036508	Felis catus	75.63	0.00e+00	918.00
IUUC-Fal-036813	Ficedula albicollis	73.99	0.00e+00	856.00
IUUC-Fox-038056	Fusarium oxysporum	44.34	6.00e-83	301.00
IUUC-Fso-038223	Fusarium solani	41.57	4.00e-81	295.00
IUUC-Gmo-038526	Gadus morhua	71.72	0.00e+00	754.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.57	3.00e-83	303.00
IUUC-Gga-040981	Gallus gallus	75.79	0.00e+00	813.00
IUUC-Gac-041437	Gasterosteus aculeatus	71.95	0.00e+00	812.00
IUUC-Gma-044072	Glycine max	36.76	7.00e-101	361.00
IUUC-Ggo-045358	Gorilla gorilla	72.89	0.00e+00	830.00
IUUC-Hsa-046068	Homo sapiens	75.79	0.00e+00	874.00
IUUC-Hvu-047646	Hordeum vulgare	37.86	1.00e-96	347.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	75.17	0.00e+00	877.00
IUUC-Lch-049565	Latimeria chalumnae	75.46	0.00e+00	891.00
IUUC-Lpe-050884	Leersia perrieri	39.64	9.00e-99	354.00
IUUC-Loc-052493	Lepisosteus oculatus	75.00	0.00e+00	885.00
IUUC-Lma-053117	Leptosphaeria maculans	42.76	1.00e-89	323.00
IUUC-Laf-054518	Loxodonta africana	74.21	0.00e+00	872.00
IUUC-Mcc-055334	Macaca mulatta	75.79	0.00e+00	872.00
IUUC-Mor-057137	Magnaporthe oryzae	42.60	4.00e-78	285.00
IUUC-Mpo-057449	Magnaporthe poae	43.96	1.00e-84	307.00
IUUC-Mtr-058045	Medicago truncatula	37.66	3.00e-103	369.00
IUUC-Mla-058864	Melampsora laricipopulina	46.48	3.00e-86	312.00
IUUC-Mga-059422	Meleagris gallopavo	72.64	0.00e+00	758.00
IUUC-Mvi-060536	Microbotryum violaceum	37.93	5.00e-72	265.00
IUUC-Mmr-061161	Microcebus murinus	74.96	0.00e+00	880.00
IUUC-Mdo-061802	Monodelphis domestica	77.13	0.00e+00	890.00
IUUC-Mmu-064357	Mus musculus	74.29	0.00e+00	865.00
IUUC-Mac-065475	Musa acuminata	40.16	2.00e-99	356.00
IUUC-Mpu-066895	Mustela putorius furo	75.46	0.00e+00	912.00
IUUC-Mlu-067862	Myotis lucifugus	75.17	0.00e+00	905.00
IUUC-Nfi-068385	Neosartorya fischeri	43.81	9.00e-93	334.00
IUUC-Ncr-068885	Neurospora crassa	38.33	4.00e-88	318.00
IUUC-Nle-069524	Nomascus leucogenys	74.96	0.00e+00	858.00
IUUC-Opr-071038	Ochotona princeps	75.46	0.00e+00	882.00
IUUC-Ont-071719	Oreochromis niloticus	70.53	0.00e+00	835.00
IUUC-Oan-072877	Ornithorhynchus anatinus	74.46	0.00e+00	816.00
IUUC-Ocu-074080	Oryctolagus cuniculus	74.79	0.00e+00	877.00
IUUC-Oba-075936	Oryza barthii	38.08	2.00e-98	353.00
IUUC-Obr-076841	Oryza brachyantha	38.13	3.00e-101	362.00
IUUC-Ogl-077686	Oryza glaberrima	38.08	1.00e-98	353.00
IUUC-Ogu-078597	Oryza glumaepatula	37.09	2.00e-95	342.00
IUUC-Oin-079791	Oryza indica	38.08	2.00e-98	353.00
IUUC-Olo-081009	Oryza longistaminata	38.43	2.00e-98	353.00
IUUC-Ome-081327	Oryza meridionalis	37.90	6.00e-98	351.00
IUUC-Oni-082334	Oryza nivara	37.28	6.00e-96	344.00
IUUC-Opu-083447	Oryza punctata	38.32	1.00e-99	357.00
IUUC-Oru-084977	Oryza rufipogon	38.08	2.00e-98	352.00
IUUC-Osa-086160	Oryza sativa	43.68	1.00e-85	309.00
IUUC-Ola-087415	Oryzias latipes	70.85	0.00e+00	791.00
IUUC-Olu-087850	Ostreococcus lucimarinus	39.17	1.00e-86	313.00
IUUC-Oga-088434	Otolemur garnettii	75.96	0.00e+00	887.00
IUUC-Oar-089872	Ovis aries	75.00	0.00e+00	909.00
IUUC-Ptr-091212	Pan troglodytes	75.79	0.00e+00	874.00
IUUC-Pan-092708	Papio anubis	87.79	1.00e-106	379.00
IUUC-Psi-093703	Pelodiscus sinensis	77.96	0.00e+00	875.00
IUUC-Pno-094953	Phaeosphaeria nodorum	44.69	7.00e-93	334.00
IUUC-Ppa-095739	Physcomitrella patens	46.86	7.00e-90	324.00
IUUC-Pfo-097515	Poecilia formosa	69.62	0.00e+00	795.00
IUUC-Pab-097951	Pongo abelii	73.95	0.00e+00	775.00
IUUC-Pop-099703	Populus trichocarpa	35.92	3.00e-82	299.00
IUUC-Pca-100426	Procavia capensis	74.67	0.00e+00	902.00
IUUC-Ppe-101152	Prunus persica	38.94	1.00e-98	353.00
IUUC-Pva-102792	Pteropus vampyrus	71.45	0.00e+00	850.00
IUUC-Pgr-103592	Puccinia graminis	43.83	4.00e-91	328.00
IUUC-Ptt-103805	Puccinia triticina	38.29	4.00e-74	272.00
IUUC-Pte-104215	Pyrenophora teres	43.90	6.00e-97	348.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	44.15	6.00e-97	348.00
IUUC-Rno-106117	Rattus norvegicus	74.46	0.00e+00	869.00
IUUC-Sce-106177	Saccharomyces cerevisiae	37.30	1.00e-60	227.00
IUUC-Sha-107006	Sarcophilus harrisii	76.29	0.00e+00	891.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	40.44	1.00e-80	294.00
IUUC-Spo-108020	Schizosaccharomyces pombe	40.92	5.00e-81	295.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	40.73	3.00e-87	315.00
IUUC-Smo-108809	Selaginella moellendorffii	41.29	1.00e-90	327.00
IUUC-Sit-110581	Setaria italica	40.47	2.00e-98	353.00
IUUC-Sly-111870	Solanum lycopersicum	36.97	5.00e-98	352.00
IUUC-Stu-112283	Solanum tuberosum	36.51	1.00e-95	343.00
IUUC-Sar-113432	Sorex araneus	53.59	2.00e-160	559.00
IUUC-Sbi-114075	Sorghum bicolor	38.82	7.00e-99	354.00
IUUC-Sre-114926	Sporisorium reilianum	42.02	1.00e-83	304.00
IUUC-Ssc-116281	Sus scrofa	88.14	4.00e-94	337.00
IUUC-Tgu-117247	Taeniopygia guttata	73.83	0.00e+00	856.00
IUUC-Tru-118075	Takifugu rubripes	66.34	0.00e+00	754.00
IUUC-Tsy-119398	Tarsius syrichta	74.70	8.00e-177	613.00
IUUC-Tni-120771	Tetraodon nigroviridis	60.66	0.00e+00	677.00
IUUC-Tca-121651	Theobroma cacao	38.03	2.00e-93	336.00
IUUC-Tre-122224	Trichoderma reesei	37.41	1.00e-75	277.00
IUUC-Tvi-122634	Trichoderma virens	38.06	2.00e-75	276.00
IUUC-Tae-123607	Triticum aestivum	38.28	2.00e-95	343.00
IUUC-Tur-126417	Triticum urartu	38.30	6.00e-94	338.00
IUUC-Tme-127016	Tuber melanosporum	42.35	1.00e-84	307.00
IUUC-Tbe-127678	Tupaia belangeri	58.51	6.00e-118	417.00
IUUC-Ttr-128598	Tursiops truncatus	70.95	0.00e+00	852.00
IUUC-Uma-129612	Ustilago maydis	41.87	1.00e-77	284.00
IUUC-Vda-129811	Verticillium dahliae	42.33	6.00e-87	315.00
IUUC-Vpa-130732	Vicugna pacos	67.60	0.00e+00	762.00
IUUC-Vvi-130832	Vitis vinifera	40.15	3.00e-97	348.00
IUUC-Xma-133552	Xiphophorus maculatus	69.45	0.00e+00	792.00
IUUC-Yli-134666	Yarrowia lipolytica	35.75	6.00e-61	228.00
IUUC-Zma-135547	Zea mays	37.52	2.00e-96	346.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence