iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020947

Ensembl Protein ID

ENSCAFP00000009145.1

UniProt Accession

E2R8X6; E2R8X6_CANLF

Genbank Protein ID

ENSCAFP00000009145

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAEX03013390

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006088.3	ENSCAFT00000009849.1	ENSCAFP00000009145.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.90e-09	36.3	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDEYYEKFKR 60
ETDSVQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFEAHQEVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGCC CTGCCAACGG GGAGCAGATC CACCTGGTGA ACTATGTGGA GGACTACCTG 60
GACTCCATCG AGTCTCTGCC TTTCGACCTG CAGAGAAACG TCTCCCTGAT GCGGGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

KEGG

cfa:476984

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	99.28	1.00e-136	478.00
IUUC-Apl-003910	Anas platyrhynchos	93.88	1.00e-128	452.00
IUUC-Aca-004874	Anolis carolinensis	92.86	1.00e-126	445.00
IUUC-Ame-011262	Astyanax mexicanus	67.59	3.00e-97	348.00
IUUC-Bta-013507	Bos taurus	91.03	5.00e-93	333.00
IUUC-Cja-018925	Callithrix jacchus	90.32	1.00e-124	439.00
IUUC-Cpo-022286	Cavia porcellus	91.95	1.00e-101	363.00
IUUC-Csa-023825	Chlorocebus sabaeus	89.96	4.00e-124	437.00
IUUC-Cho-024577	Choloepus hoffmanni	94.85	7.00e-103	366.00
IUUC-Dno-029834	Dasypus novemcinctus	96.42	4.00e-133	467.00
IUUC-Ete-032408	Echinops telfairi	91.91	6.00e-98	350.00
IUUC-Eca-034244	Equus caballus	96.58	3.00e-105	374.00
IUUC-Fca-035391	Felis catus	93.82	3.00e-115	407.00
IUUC-Fal-036838	Ficedula albicollis	92.83	4.00e-128	450.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gga-040619	Gallus gallus	93.19	5.00e-128	450.00
IUUC-Ggo-045481	Gorilla gorilla	87.29	2.00e-97	348.00
IUUC-Hsa-046170	Homo sapiens	87.29	2.00e-97	348.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	96.15	8.00e-106	375.00
IUUC-Lch-050397	Latimeria chalumnae	89.61	2.00e-124	437.00
IUUC-Loc-052038	Lepisosteus oculatus	82.56	2.00e-101	362.00
IUUC-Laf-054126	Loxodonta africana	95.70	3.00e-132	464.00
IUUC-Mcc-055031	Macaca mulatta	87.66	7.00e-97	347.00
IUUC-Meu-056248	Macropus eugenii	93.70	1.00e-103	369.00
IUUC-Mga-059217	Meleagris gallopavo	92.27	4.00e-100	357.00
IUUC-Mmr-061581	Microcebus murinus	94.65	6.00e-109	386.00
IUUC-Mdo-062452	Monodelphis domestica	96.06	1.00e-131	462.00
IUUC-Mmu-063412	Mus musculus	94.62	2.00e-130	457.00
IUUC-Mpu-066479	Mustela putorius furo	99.15	8.00e-109	386.00
IUUC-Nle-069122	Nomascus leucogenys	89.61	1.00e-123	435.00
IUUC-Opr-070835	Ochotona princeps	86.27	2.00e-85	308.00
IUUC-Oan-073023	Ornithorhynchus anatinus	92.11	2.00e-125	441.00
IUUC-Ocu-073779	Oryctolagus cuniculus	89.17	1.00e-95	342.00
IUUC-Oga-087954	Otolemur garnettii	94.62	1.00e-130	459.00
IUUC-Oar-090006	Ovis aries	92.83	4.00e-126	444.00
IUUC-Ptr-090589	Pan troglodytes	89.96	3.00e-124	437.00
IUUC-Pan-091896	Papio anubis	87.66	4.00e-97	348.00
IUUC-Psi-093266	Pelodiscus sinensis	94.62	2.00e-130	457.00
IUUC-Pma-094265	Petromyzon marinus	75.34	7.00e-34	135.00
IUUC-Pab-098253	Pongo abelii	89.96	6.00e-124	436.00
IUUC-Pva-102753	Pteropus vampyrus	86.49	7.00e-95	340.00
IUUC-Rno-105964	Rattus norvegicus	93.59	9.00e-93	332.00
IUUC-Sha-107270	Sarcophilus harrisii	95.34	4.00e-130	456.00
IUUC-Tgu-116822	Taeniopygia guttata	93.19	2.00e-128	451.00
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.80
IUUC-Ttr-128672	Tursiops truncatus	94.89	2.00e-103	368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence