iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074316

Ensembl Protein ID

ENSOCUP00000006274.2

UniProt Accession

G1SSP0; G1SSP0_RABIT

Genbank Protein ID

ENSOCUP00000006274

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02005947

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007258.3	ENSOCUT00000007259.3	ENSOCUP00000006274.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.50e-30	101.4	489	520
UBD/Beta-Prp	6.20e-45	153.7	485	699

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHtd v++la+   +  +l+s+s Dgt+++W++
   Q: 489  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNT 520
           8**********9853.89*************96 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlk.....ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+   + + +++++     g  +sv ++s++p  + +v+  +  +  ++++et+q 
   Q: 485  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTAeAAPALSVFNdnkelGIPASVDLVSSDP--SLMVASFSKGYTSIFNMETQQR 571
           5689******************************7661566666666555555555555566666..6666666788************ PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t  + +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 572  ILTlesnpdTTINSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 659
           **9888865444455557778899999**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 660  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 699
           ***********999999******************97665 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

AQIAFLQGER KGQENLKKDL VRRIKMLEYA LKQERAKYHK LKYGTELNQG DMKPPSYDSV 60
DEGNETEVQP QQNSQLMWKQ GRQLLRQYLQ EVGYTDTILD VKSKRVRALL GFSSDVTDRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAATTAAGA AGAGGGAGCT GTTTATCGCG TGGTCTAATC TGAGTTTTGT CTTTTTCTCC 60
TCTACTTAGG CCCAGATTGC CTTTCTTCAG GGAGAAAGGA AAGGCCAAGA AAATTTGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	96.73	0.00e+00	1269.00
IUUC-Apl-003927	Anas platyrhynchos	87.64	0.00e+00	1110.00
IUUC-Aca-004933	Anolis carolinensis	80.19	0.00e+00	1116.00
IUUC-Ame-010997	Astyanax mexicanus	74.58	0.00e+00	970.00
IUUC-Bta-013077	Bos taurus	96.59	0.00e+00	1266.00
IUUC-Cja-018973	Callithrix jacchus	97.16	0.00e+00	1277.00
IUUC-Cfa-020988	Canis familiaris	93.03	0.00e+00	1213.00
IUUC-Cpo-022496	Cavia porcellus	95.73	0.00e+00	1269.00
IUUC-Csa-023829	Chlorocebus sabaeus	96.87	0.00e+00	1270.00
IUUC-Dre-028560	Danio rerio	69.32	0.00e+00	877.00
IUUC-Dno-029742	Dasypus novemcinctus	89.90	0.00e+00	1198.00
IUUC-Dor-030721	Dipodomys ordii	87.34	0.00e+00	1134.00
IUUC-Eca-033760	Equus caballus	96.73	0.00e+00	1270.00
IUUC-Eeu-034953	Erinaceus europaeus	95.31	0.00e+00	738.00
IUUC-Fca-036530	Felis catus	96.73	0.00e+00	1274.00
IUUC-Fal-037353	Ficedula albicollis	81.65	0.00e+00	887.00
IUUC-Gmo-039653	Gadus morhua	50.56	0.00e+00	636.00
IUUC-Gga-040132	Gallus gallus	87.62	0.00e+00	1103.00
IUUC-Gac-041713	Gasterosteus aculeatus	74.48	0.00e+00	967.00
IUUC-Ggo-045455	Gorilla gorilla	86.56	0.00e+00	1078.00
IUUC-Hsa-046415	Homo sapiens	97.01	0.00e+00	1273.00
IUUC-Lch-050475	Latimeria chalumnae	83.40	0.00e+00	1088.00
IUUC-Loc-051859	Lepisosteus oculatus	78.82	0.00e+00	1037.00
IUUC-Laf-053537	Loxodonta africana	96.16	0.00e+00	1283.00
IUUC-Mcc-055817	Macaca mulatta	96.87	0.00e+00	1270.00
IUUC-Meu-055946	Macropus eugenii	67.76	0.00e+00	783.00
IUUC-Mga-059694	Meleagris gallopavo	87.48	0.00e+00	1102.00
IUUC-Mmr-060768	Microcebus murinus	97.01	0.00e+00	1270.00
IUUC-Mdo-061901	Monodelphis domestica	87.70	0.00e+00	1189.00
IUUC-Mmu-064154	Mus musculus	94.88	0.00e+00	1251.00
IUUC-Mpu-065827	Mustela putorius furo	91.26	0.00e+00	1259.00
IUUC-Mlu-067102	Myotis lucifugus	96.02	0.00e+00	1265.00
IUUC-Ncr-068831	Neurospora crassa	39.60	5.00e-22	100.00
IUUC-Nle-070008	Nomascus leucogenys	97.44	0.00e+00	1278.00
IUUC-Opr-071067	Ochotona princeps	63.12	8.00e-164	570.00
IUUC-Ont-072025	Oreochromis niloticus	74.19	0.00e+00	950.00
IUUC-Oan-072950	Ornithorhynchus anatinus	91.63	0.00e+00	1157.00
IUUC-Ola-087279	Oryzias latipes	71.87	0.00e+00	929.00
IUUC-Oga-088284	Otolemur garnettii	96.44	0.00e+00	1269.00
IUUC-Oar-090304	Ovis aries	96.87	0.00e+00	1270.00
IUUC-Ptr-091052	Pan troglodytes	97.16	0.00e+00	1275.00
IUUC-Pan-092270	Papio anubis	92.77	0.00e+00	1229.00
IUUC-Psi-093907	Pelodiscus sinensis	88.05	0.00e+00	1033.00
IUUC-Pfo-097042	Poecilia formosa	72.97	0.00e+00	1024.00
IUUC-Pab-098110	Pongo abelii	97.16	0.00e+00	1275.00
IUUC-Pca-100266	Procavia capensis	83.00	0.00e+00	875.00
IUUC-Pva-102824	Pteropus vampyrus	94.45	0.00e+00	1220.00
IUUC-Rno-105638	Rattus norvegicus	95.45	0.00e+00	1264.00
IUUC-Sha-107004	Sarcophilus harrisii	88.10	0.00e+00	1107.00
IUUC-Ssc-115280	Sus scrofa	97.30	0.00e+00	1277.00
IUUC-Tgu-116759	Taeniopygia guttata	88.05	0.00e+00	1127.00
IUUC-Tru-117944	Takifugu rubripes	73.63	0.00e+00	948.00
IUUC-Tsy-119405	Tarsius syrichta	85.35	0.00e+00	1064.00
IUUC-Tni-120571	Tetraodon nigroviridis	73.01	0.00e+00	955.00
IUUC-Vpa-130294	Vicugna pacos	96.16	0.00e+00	1253.00
IUUC-Xma-134233	Xiphophorus maculatus	66.76	0.00e+00	865.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence