iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116630

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01027090

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000009903.1	ENSTGUT00000010328.1	ENSTGUP00000010220.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-21	75.9	186	218
UBD/Beta-Prp	5.20e-41	140.6	257	393

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H+ +v+c++f+++l+vsGs+D t kvW+l+ g+
   Q: 186  HEQEVNCVDFQGGLIVSGSRDRTAKVWSLSAGR 218
           99********669***************99887 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtl.tgghtdsvysls.fdsngkelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sD 243
           +r+Wdl++g+ll+ l t + ++    l+ f ++   l+s+++d+++++wd++  t +cv+++++ h++  +++r + +++ ++sgs   
   Q: 257  LRIWDLESGQLLTCLgT-DFHRGAGVLDvFYETPSLLLSCGYDTYIRYWDIRtsTRKCVQEWEEpHDSALYCIRSD-KNHMIASGSsYY 343
           79*************54.45555555554888889*****************9999*******9899999999988.999999999789 PP
   S: 244  gsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           g++r+Wd+r+  +l+++ l+  ++++v +l+f+  +l+++ + s ++++++
   Q: 344  GVVRLWDKRQTRCLQSFHLSSPTSSPVYCLRFSTTHLYAALA-SALHVLDF 393
           *********************************999988755.55666655 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

PPPPSSSPPS SPLWTLPEEM MLLICSYLDA QPLGRLAQVC RRLRFLSSRD VLWRRIARGC 60
LNSGFTQLGT DLAAGIPVKE RVKVSQNWRH GRCRRETVLK WKCNLMPWME LDGEYLYLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCGC CTTCCTCTTC CCCACCTTCC TAATGTGAAA CCTATGTGCT CTAATATCTC 60
TGAGTCCAGA TAGAATCTCT AAGAAACCTC AGAGTTTCTG GTGGCCTGTA TGAAATTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	71.97	8.00e-164	569.00
IUUC-Apl-003837	Anas platyrhynchos	95.96	0.00e+00	643.00
IUUC-Aca-004776	Anolis carolinensis	79.09	1.00e-164	572.00
IUUC-Ame-010651	Astyanax mexicanus	65.63	3.00e-124	437.00
IUUC-Bta-013495	Bos taurus	71.43	7.00e-155	539.00
IUUC-Cja-018901	Callithrix jacchus	71.04	3.00e-152	530.00
IUUC-Cfa-021251	Canis familiaris	71.70	7.00e-163	566.00
IUUC-Cpo-021750	Cavia porcellus	72.41	6.00e-142	496.00
IUUC-Csa-024026	Chlorocebus sabaeus	71.04	3.00e-159	554.00
IUUC-Cho-024496	Choloepus hoffmanni	54.92	7.00e-112	396.00
IUUC-Cin-025142	Ciona intestinalis	30.68	7.00e-28	116.00
IUUC-Csv-025883	Ciona savignyi	36.78	5.00e-69	254.00
IUUC-Dre-027447	Danio rerio	62.73	3.00e-144	504.00
IUUC-Dno-029572	Dasypus novemcinctus	60.59	1.00e-125	442.00
IUUC-Dor-030982	Dipodomys ordii	64.75	1.00e-140	492.00
IUUC-Ete-032917	Echinops telfairi	72.27	8.00e-144	502.00
IUUC-Eca-033969	Equus caballus	71.31	4.00e-153	533.00
IUUC-Eeu-034850	Erinaceus europaeus	66.94	5.00e-143	500.00
IUUC-Fca-036182	Felis catus	68.19	2.00e-149	521.00
IUUC-Fal-037391	Ficedula albicollis	92.57	0.00e+00	693.00
IUUC-Gmo-038632	Gadus morhua	59.01	6.00e-133	466.00
IUUC-Gga-040783	Gallus gallus	93.83	0.00e+00	705.00
IUUC-Gac-042314	Gasterosteus aculeatus	55.18	1.00e-111	395.00
IUUC-Ggo-044739	Gorilla gorilla	71.31	5.00e-159	553.00
IUUC-Hsa-046705	Homo sapiens	71.31	2.00e-152	531.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	72.03	6.00e-126	442.00
IUUC-Loc-052397	Lepisosteus oculatus	71.39	8.00e-154	536.00
IUUC-Laf-054544	Loxodonta africana	70.57	3.00e-143	500.00
IUUC-Meu-056363	Macropus eugenii	61.32	3.00e-100	357.00
IUUC-Mga-059275	Meleagris gallopavo	95.34	0.00e+00	642.00
IUUC-Mmr-060906	Microcebus murinus	70.77	5.00e-158	550.00
IUUC-Mdo-062400	Monodelphis domestica	79.73	2.00e-178	618.00
IUUC-Mmu-063556	Mus musculus	71.86	6.00e-159	553.00
IUUC-Mpu-066500	Mustela putorius furo	71.70	4.00e-163	566.00
IUUC-Mlu-068074	Myotis lucifugus	71.65	2.00e-142	498.00
IUUC-Nle-069601	Nomascus leucogenys	71.31	4.00e-159	553.00
IUUC-Opr-070904	Ochotona princeps	65.12	3.00e-109	387.00
IUUC-Ont-072679	Oreochromis niloticus	57.85	2.00e-127	448.00
IUUC-Oan-073434	Ornithorhynchus anatinus	73.95	4.00e-86	310.00
IUUC-Ocu-074649	Oryctolagus cuniculus	71.31	2.00e-157	548.00
IUUC-Ola-087336	Oryzias latipes	51.95	1.00e-108	385.00
IUUC-Oga-088590	Otolemur garnettii	70.22	1.00e-150	525.00
IUUC-Oar-090178	Ovis aries	68.82	8.00e-142	496.00
IUUC-Pan-092881	Papio anubis	71.04	2.00e-159	554.00
IUUC-Pfo-096176	Poecilia formosa	56.73	2.00e-117	415.00
IUUC-Pab-098285	Pongo abelii	71.31	5.00e-159	554.00
IUUC-Pca-100888	Procavia capensis	69.81	7.00e-150	523.00
IUUC-Pva-102184	Pteropus vampyrus	61.48	3.00e-128	451.00
IUUC-Rno-105668	Rattus norvegicus	70.22	4.00e-156	543.00
IUUC-Sha-106629	Sarcophilus harrisii	81.76	2.00e-158	550.00
IUUC-Ssc-116183	Sus scrofa	72.78	4.00e-165	574.00
IUUC-Tru-118761	Takifugu rubripes	55.76	3.00e-123	434.00
IUUC-Tni-120651	Tetraodon nigroviridis	53.47	9.00e-63	232.00
IUUC-Ttr-128582	Tursiops truncatus	71.97	4.00e-154	536.00
IUUC-Vpa-130431	Vicugna pacos	58.77	2.00e-73	268.00
IUUC-Xtr-132655	Xenopus tropicalis	73.17	2.00e-163	568.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence