iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059460

Ensembl Protein ID

ENSMGAP00000010619.1

UniProt Accession

G1NCV5; G1NCV5_MELGA

Protein Name

Uncharacterized protein

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010232.1	ENSMGAT00000011480.1	ENSMGAP00000010619.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	84.54	0.00e+00	1316.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MQSTSNYLWL LSDILGQGAT ANVFRGRHKK TGDLYAVKVF NSISFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTTR HKVLVMEFCP CGSLYTVLEE PSNAFGLPES EFLIVLRDVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGAGCA CCTCCAATTA TCTCTGGCTG TTGTCTGACA TTCTAGGACA AGGAGCTACT 60
GCAAATGTTT TCCGGGGACG ACATAAGGTT TGTGAAGAGT TACCAACAGA AATGAAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	85.36	0.00e+00	1329.00
IUUC-Apl-004028	Anas platyrhynchos	95.08	0.00e+00	1444.00
IUUC-Aca-004998	Anolis carolinensis	84.40	0.00e+00	1303.00
IUUC-Ame-011617	Astyanax mexicanus	70.15	0.00e+00	1042.00
IUUC-Bta-012799	Bos taurus	85.09	0.00e+00	1325.00
IUUC-Cja-019357	Callithrix jacchus	85.36	0.00e+00	1330.00
IUUC-Cfa-020309	Canis familiaris	84.95	0.00e+00	1324.00
IUUC-Cpo-022062	Cavia porcellus	84.82	0.00e+00	1316.00
IUUC-Csa-023517	Chlorocebus sabaeus	85.64	0.00e+00	1332.00
IUUC-Cho-025037	Choloepus hoffmanni	79.39	0.00e+00	841.00
IUUC-Cin-025580	Ciona intestinalis	38.71	2.00e-147	516.00
IUUC-Csv-025818	Ciona savignyi	41.34	2.00e-142	499.00
IUUC-Dre-027527	Danio rerio	69.96	0.00e+00	1054.00
IUUC-Dno-029475	Dasypus novemcinctus	75.65	0.00e+00	1022.00
IUUC-Dme-031698	Drosophila melanogaster	38.37	2.00e-128	452.00
IUUC-Ete-033090	Echinops telfairi	73.19	0.00e+00	1092.00
IUUC-Eca-033996	Equus caballus	85.09	0.00e+00	1320.00
IUUC-Eeu-035082	Erinaceus europaeus	78.96	0.00e+00	785.00
IUUC-Fca-035921	Felis catus	82.56	0.00e+00	1274.00
IUUC-Fal-037406	Ficedula albicollis	96.03	0.00e+00	1455.00
IUUC-Gmo-038721	Gadus morhua	69.69	0.00e+00	1026.00
IUUC-Gga-041234	Gallus gallus	97.40	0.00e+00	1479.00
IUUC-Gac-042315	Gasterosteus aculeatus	70.15	0.00e+00	1045.00
IUUC-Ggo-044885	Gorilla gorilla	79.48	0.00e+00	1219.00
IUUC-Hsa-046847	Homo sapiens	85.36	0.00e+00	1328.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	84.63	0.00e+00	1318.00
IUUC-Lch-049731	Latimeria chalumnae	53.49	0.00e+00	765.00
IUUC-Loc-051879	Lepisosteus oculatus	71.86	0.00e+00	1080.00
IUUC-Laf-054232	Loxodonta africana	84.68	0.00e+00	1322.00
IUUC-Mcc-055447	Macaca mulatta	85.64	0.00e+00	1332.00
IUUC-Meu-056138	Macropus eugenii	92.49	0.00e+00	652.00
IUUC-Mmr-061445	Microcebus murinus	85.64	0.00e+00	1333.00
IUUC-Mmu-064107	Mus musculus	84.54	0.00e+00	1291.00
IUUC-Mpu-066834	Mustela putorius furo	85.77	0.00e+00	1333.00
IUUC-Mlu-068006	Myotis lucifugus	83.45	0.00e+00	1283.00
IUUC-Nle-069280	Nomascus leucogenys	85.23	0.00e+00	1328.00
IUUC-Opr-070728	Ochotona princeps	76.95	0.00e+00	1050.00
IUUC-Ont-071621	Oreochromis niloticus	71.17	0.00e+00	1058.00
IUUC-Oan-073162	Ornithorhynchus anatinus	84.76	0.00e+00	1258.00
IUUC-Ocu-074787	Oryctolagus cuniculus	85.77	0.00e+00	1336.00
IUUC-Ola-086737	Oryzias latipes	32.74	1.00e-26	114.00
IUUC-Oga-088764	Otolemur garnettii	84.68	0.00e+00	1324.00
IUUC-Oar-090333	Ovis aries	84.82	0.00e+00	1325.00
IUUC-Ptr-090568	Pan troglodytes	85.50	0.00e+00	1328.00
IUUC-Pan-091979	Papio anubis	85.52	0.00e+00	1328.00
IUUC-Psi-093336	Pelodiscus sinensis	88.51	0.00e+00	1353.00
IUUC-Pma-094200	Petromyzon marinus	42.74	4.00e-166	577.00
IUUC-Pfo-096354	Poecilia formosa	70.29	0.00e+00	1055.00
IUUC-Pab-098499	Pongo abelii	85.36	0.00e+00	1329.00
IUUC-Pva-102454	Pteropus vampyrus	83.58	0.00e+00	1289.00
IUUC-Rno-105595	Rattus norvegicus	83.86	0.00e+00	1279.00
IUUC-Sha-106864	Sarcophilus harrisii	85.79	0.00e+00	1330.00
IUUC-Sar-113728	Sorex araneus	77.64	0.00e+00	1122.00
IUUC-Tgu-117200	Taeniopygia guttata	94.14	0.00e+00	1427.00
IUUC-Tsy-119017	Tarsius syrichta	86.08	0.00e+00	991.00
IUUC-Tni-120724	Tetraodon nigroviridis	70.33	0.00e+00	1049.00
IUUC-Tbe-127887	Tupaia belangeri	77.55	0.00e+00	946.00
IUUC-Ttr-129111	Tursiops truncatus	77.84	0.00e+00	1187.00
IUUC-Vpa-130724	Vicugna pacos	85.50	0.00e+00	1334.00
IUUC-Xtr-132091	Xenopus tropicalis	74.49	0.00e+00	1157.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence