iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089919

Ensembl Protein ID

ENSOARP00000021722.1

UniProt Accession

W5QG73; W5QG73_SHEEP

Genbank Protein ID

ENSOARP00000021722

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01076333

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020221.1	ENSOART00000022025.1	ENSOARP00000021722.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-69	235.2	1906	2251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1906 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1985
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1986 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2044
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2045 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2126
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 2127 MTPYTEDflmgksdrkegfkevsDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2213
           **********99999999999986666777***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2214 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2251
           7779********************************96 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

LCEIFVNLIY FFYFLSVSDI EGGDGLQLRK EHTLKIFAYI NSWTQRQCLC CFKEYKHLEI 60
FNQVVCALIN LVIAQVQVLR DQLCKHCTTI NIDSTWQDES NQAEEPQNIE RECNEGSTER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTATGTGAAA TATTTGTAAA TCTAATTTTT TTTAAGTATG GCTTTTTTTT TTGGCCACTG 60
TGTGTAGCAT GCAGGATCTT AGTTCCCTGA CCAGGGATTG AACCTGTGTA CCTTGCAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	98.50	0.00e+00	6859.00
IUUC-Apl-003284	Anas platyrhynchos	94.64	0.00e+00	6309.00
IUUC-Aca-004415	Anolis carolinensis	92.74	0.00e+00	6438.00
IUUC-Acl-008140	Aspergillus clavatus	28.62	3.00e-64	241.00
IUUC-Afl-008381	Aspergillus flavus	28.97	1.00e-64	242.00
IUUC-Afu-008857	Aspergillus fumigatus	27.35	4.00e-64	241.00
IUUC-Ani-009257	Aspergillus nidulans	28.68	6.00e-56	214.00
IUUC-Ang-009759	Aspergillus niger	27.72	5.00e-64	241.00
IUUC-Aor-009931	Aspergillus oryzae	28.97	1.00e-64	243.00
IUUC-Ate-010246	Aspergillus terreus	29.24	2.00e-53	206.00
IUUC-Ame-011219	Astyanax mexicanus	64.86	0.00e+00	2480.00
IUUC-Bgr-012195	Blumeria graminis	27.63	2.00e-64	242.00
IUUC-Bta-012989	Bos taurus	99.35	0.00e+00	6899.00
IUUC-Bci-013798	Botrytis cinerea	32.44	3.00e-58	221.00
IUUC-Cja-018974	Callithrix jacchus	95.99	0.00e+00	815.00
IUUC-Cfa-021214	Canis familiaris	98.73	0.00e+00	6873.00
IUUC-Cpo-021912	Cavia porcellus	97.66	0.00e+00	4747.00
IUUC-Csa-023658	Chlorocebus sabaeus	97.72	0.00e+00	6813.00
IUUC-Cho-024971	Choloepus hoffmanni	83.90	0.00e+00	3203.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	28.46	2.00e-63	238.00
IUUC-Dre-027428	Danio rerio	85.24	0.00e+00	4641.00
IUUC-Dno-029690	Dasypus novemcinctus	97.48	0.00e+00	6657.00
IUUC-Dor-030817	Dipodomys ordii	88.19	0.00e+00	2138.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	1.00e-35	147.00
IUUC-Dme-032102	Drosophila melanogaster	54.00	0.00e+00	847.00
IUUC-Ete-032552	Echinops telfairi	93.74	0.00e+00	2994.00
IUUC-Eca-033457	Equus caballus	98.50	0.00e+00	6563.00
IUUC-Eeu-035118	Erinaceus europaeus	93.95	0.00e+00	3067.00
IUUC-Fca-036213	Felis catus	96.55	0.00e+00	5076.00
IUUC-Fal-037643	Ficedula albicollis	92.02	0.00e+00	6401.00
IUUC-Fox-037971	Fusarium oxysporum	27.27	2.00e-63	238.00
IUUC-Fso-038108	Fusarium solani	27.10	5.00e-60	227.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.16	2.00e-62	235.00
IUUC-Gga-040511	Gallus gallus	92.08	0.00e+00	6426.00
IUUC-Gac-042024	Gasterosteus aculeatus	87.66	0.00e+00	5008.00
IUUC-Ggo-044924	Gorilla gorilla	94.11	0.00e+00	6274.00
IUUC-Hsa-046913	Homo sapiens	97.81	0.00e+00	6846.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	98.36	0.00e+00	6851.00
IUUC-Lch-049675	Latimeria chalumnae	85.73	0.00e+00	4877.00
IUUC-Loc-052832	Lepisosteus oculatus	86.68	0.00e+00	5957.00
IUUC-Lma-053130	Leptosphaeria maculans	27.49	3.00e-61	231.00
IUUC-Laf-054169	Loxodonta africana	96.81	0.00e+00	6796.00
IUUC-Mcc-055847	Macaca mulatta	97.23	0.00e+00	6728.00
IUUC-Meu-056327	Macropus eugenii	85.17	0.00e+00	1561.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	8.00e-62	233.00
IUUC-Mpo-057310	Magnaporthe poae	26.43	3.00e-60	228.00
IUUC-Mmr-060780	Microcebus murinus	98.03	0.00e+00	6855.00
IUUC-Mdo-062308	Monodelphis domestica	92.53	0.00e+00	6179.00
IUUC-Mmu-063457	Mus musculus	96.04	0.00e+00	6729.00
IUUC-Mpu-066917	Mustela putorius furo	96.37	0.00e+00	6670.00
IUUC-Mlu-067696	Myotis lucifugus	98.28	0.00e+00	6819.00
IUUC-Nfi-068259	Neosartorya fischeri	27.70	2.00e-64	242.00
IUUC-Ncr-068911	Neurospora crassa	25.71	1.00e-59	226.00
IUUC-Nle-069586	Nomascus leucogenys	98.02	0.00e+00	6868.00
IUUC-Opr-070447	Ochotona princeps	93.60	0.00e+00	2879.00
IUUC-Ont-072396	Oreochromis niloticus	84.59	0.00e+00	5476.00
IUUC-Oan-073147	Ornithorhynchus anatinus	94.47	0.00e+00	6595.00
IUUC-Ocu-074324	Oryctolagus cuniculus	97.80	0.00e+00	6802.00
IUUC-Ola-086312	Oryzias latipes	81.99	0.00e+00	5293.00
IUUC-Oga-088878	Otolemur garnettii	98.19	0.00e+00	6846.00
IUUC-Ptr-090713	Pan troglodytes	98.22	0.00e+00	6289.00
IUUC-Pan-091957	Papio anubis	98.73	0.00e+00	5120.00
IUUC-Psi-093240	Pelodiscus sinensis	93.69	0.00e+00	6521.00
IUUC-Pma-094469	Petromyzon marinus	72.99	0.00e+00	4092.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.39	4.00e-57	218.00
IUUC-Pfo-097159	Poecilia formosa	81.61	0.00e+00	5522.00
IUUC-Pab-098003	Pongo abelii	97.53	0.00e+00	6496.00
IUUC-Pca-100799	Procavia capensis	90.90	0.00e+00	1939.00
IUUC-Pva-103226	Pteropus vampyrus	92.98	0.00e+00	6409.00
IUUC-Pte-104235	Pyrenophora teres	32.13	2.00e-58	222.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.43	3.00e-60	228.00
IUUC-Rno-105389	Rattus norvegicus	96.37	0.00e+00	5538.00
IUUC-Sha-106979	Sarcophilus harrisii	94.65	0.00e+00	6586.00
IUUC-Sar-113444	Sorex araneus	91.28	0.00e+00	5988.00
IUUC-Ssc-115815	Sus scrofa	98.22	0.00e+00	5696.00
IUUC-Tgu-117470	Taeniopygia guttata	93.95	0.00e+00	6236.00
IUUC-Tru-118543	Takifugu rubripes	82.12	0.00e+00	5377.00
IUUC-Tsy-119081	Tarsius syrichta	89.62	0.00e+00	4872.00
IUUC-Tni-120294	Tetraodon nigroviridis	81.90	9.00e-165	572.00
IUUC-Tre-122057	Trichoderma reesei	29.56	5.00e-62	234.00
IUUC-Tvi-122570	Trichoderma virens	35.89	2.00e-59	225.00
IUUC-Tme-127154	Tuber melanosporum	26.81	1.00e-59	225.00
IUUC-Tbe-127801	Tupaia belangeri	86.81	0.00e+00	3317.00
IUUC-Ttr-129262	Tursiops truncatus	93.96	0.00e+00	6485.00
IUUC-Vda-129686	Verticillium dahliae	28.06	3.00e-62	235.00
IUUC-Vpa-130484	Vicugna pacos	96.23	0.00e+00	5297.00
IUUC-Xtr-131769	Xenopus tropicalis	86.05	0.00e+00	6066.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence