iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072537

Ensembl Protein ID

ENSONIP00000026362.1

UniProt Accession

I3KZ15; I3KZ15_ORENI

Genbank Protein ID

ENSONIP00000026362

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01004907

Gene Name

socs9; LOC100693056

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000021059.1	ENSONIT00000026385.1	ENSONIP00000026362.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.10e-14	53.0	488	532

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 6    llrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           + r++p+SLqh+CR +I +c++++++   + LP+P++Lk++L++++y+
   Q: 488  IHRTQPFSLQHICRAVISSCTTYDGI---NMLPIPNALKKHLKEYHYK 532
           5689**********************...****************985 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSLPKDSGNR GKDRERGARP KVRQSRSEER RDAGGGRKGG KGKKKGLSSH DAAAERPVSD 60
GFEYGELLSE LETRDQSSPS PLRDSWRWQG FEVAASLLGQ ERVTAKPTLG ATGSAAELPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCATTAC CAAAGGACTC AGGGAACCGA GGAAAAGATC GAGAGAGGGG GGCTCGTCCC 60
AAGGTGAGAC AGAGCCGGTC AGAGGAGAGA CGAGATGCAG GCGGTGGAAG GAAAGGTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	80.23	4.00e-86	311.00
IUUC-Ame-010732	Astyanax mexicanus	66.23	1.00e-175	609.00
IUUC-Bol-016597	Brassica oleracea	32.81	5.20e-02	33.10
IUUC-Dme-031965	Drosophila melanogaster	70.76	4.00e-73	269.00
IUUC-Eeu-035208	Erinaceus europaeus	79.19	2.00e-85	310.00
IUUC-Gac-041931	Gasterosteus aculeatus	80.82	3.00e-178	617.00
IUUC-Loc-051791	Lepisosteus oculatus	66.94	1.00e-164	573.00
IUUC-Pfo-097139	Poecilia formosa	80.11	0.00e+00	770.00
IUUC-Pop-098820	Populus trichocarpa	44.12	5.90e-02	32.30
IUUC-Vvi-131327	Vitis vinifera	45.95	3.20e-02	33.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence