iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037087

Ensembl Protein ID

ENSFALP00000015926.1

UniProt Accession

U3KLM2; U3KLM2_FICAL

Genbank Protein ID

ENSFALP00000015926

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020255

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000015312.1	ENSFALT00000015992.1	ENSFALP00000015926.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	83.89	8.00e-153	537.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

RMAGCGEVDH SINMLPTNRK TNESCTNAAP SLQVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

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Nucleotide Sequence
(Fasta)

AGGATGGCTG GCTGTGGTGA AGTAGATCAT TCAATCAACA TGCTTCCCAC AAATAGGAAG 60
ACAAATGAGT CGTGTACCAA TGCAGCACCT TCCCTGCAAG TCCCTGAATG CGCCATCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	82.83	7.00e-135	473.00
IUUC-Apl-004143	Anas platyrhynchos	91.78	4.00e-145	507.00
IUUC-Aca-004557	Anolis carolinensis	85.59	2.00e-139	488.00
IUUC-Ame-011088	Astyanax mexicanus	62.02	5.00e-84	304.00
IUUC-Bta-012639	Bos taurus	84.38	2.00e-133	468.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	6.00e-19	87.00
IUUC-Cja-019397	Callithrix jacchus	83.06	3.00e-137	481.00
IUUC-Cfa-021140	Canis familiaris	82.50	1.00e-141	495.00
IUUC-Cpo-021387	Cavia porcellus	75.42	1.00e-143	501.00
IUUC-Csa-023503	Chlorocebus sabaeus	86.65	2.00e-137	481.00
IUUC-Cho-024895	Choloepus hoffmanni	80.00	2.00e-118	418.00
IUUC-Cin-025455	Ciona intestinalis	52.56	1.00e-43	168.00
IUUC-Dre-028824	Danio rerio	47.69	2.00e-84	305.00
IUUC-Dno-029269	Dasypus novemcinctus	82.83	5.00e-141	493.00
IUUC-Dor-030592	Dipodomys ordii	76.94	3.00e-142	497.00
IUUC-Dme-031618	Drosophila melanogaster	58.00	7.00e-56	211.00
IUUC-Ete-032478	Echinops telfairi	83.75	3.00e-144	504.00
IUUC-Eca-033389	Equus caballus	84.51	7.00e-153	532.00
IUUC-Fca-035488	Felis catus	84.08	1.00e-140	491.00
IUUC-Gga-040401	Gallus gallus	92.90	8.00e-154	535.00
IUUC-Gac-042412	Gasterosteus aculeatus	63.94	1.00e-85	309.00
IUUC-Ggo-045417	Gorilla gorilla	90.04	1.00e-135	475.00
IUUC-Hsa-045790	Homo sapiens	83.06	5.00e-137	479.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	78.27	2.00e-144	504.00
IUUC-Lch-049493	Latimeria chalumnae	72.27	2.00e-114	404.00
IUUC-Loc-052927	Lepisosteus oculatus	61.20	1.00e-103	369.00
IUUC-Laf-053904	Loxodonta africana	81.99	3.00e-142	497.00
IUUC-Mcc-055427	Macaca mulatta	82.50	7.00e-139	486.00
IUUC-Mmr-060580	Microcebus murinus	83.80	2.00e-136	478.00
IUUC-Mdo-062094	Monodelphis domestica	94.66	2.00e-76	276.00
IUUC-Mmu-063363	Mus musculus	77.22	1.00e-143	501.00
IUUC-Mpu-066816	Mustela putorius furo	83.66	1.00e-132	466.00
IUUC-Mlu-067433	Myotis lucifugus	82.83	1.00e-152	531.00
IUUC-Nle-068986	Nomascus leucogenys	83.61	4.00e-149	520.00
IUUC-Ont-072670	Oreochromis niloticus	67.11	5.00e-82	297.00
IUUC-Oan-073330	Ornithorhynchus anatinus	88.06	1.00e-106	378.00
IUUC-Ocu-074161	Oryctolagus cuniculus	84.09	2.00e-143	501.00
IUUC-Ola-086902	Oryzias latipes	60.58	3.00e-85	308.00
IUUC-Oga-089159	Otolemur garnettii	83.10	4.00e-155	540.00
IUUC-Oar-089586	Ovis aries	83.38	6.00e-126	443.00
IUUC-Ptr-090987	Pan troglodytes	83.06	5.00e-137	479.00
IUUC-Pan-091867	Papio anubis	82.55	2.00e-139	488.00
IUUC-Psi-094024	Pelodiscus sinensis	88.39	7.00e-151	526.00
IUUC-Pfo-097108	Poecilia formosa	51.84	7.00e-85	306.00
IUUC-Pab-097997	Pongo abelii	82.50	2.00e-140	491.00
IUUC-Pca-100260	Procavia capensis	82.07	6.00e-139	486.00
IUUC-Pva-103140	Pteropus vampyrus	82.50	3.00e-143	501.00
IUUC-Rno-105795	Rattus norvegicus	77.75	8.00e-144	502.00
IUUC-Sha-107033	Sarcophilus harrisii	86.12	5.00e-152	530.00
IUUC-Sit-110105	Setaria italica	42.31	6.00e-06	44.70
IUUC-Ssc-116395	Sus scrofa	83.66	1.00e-157	548.00
IUUC-Tgu-116685	Taeniopygia guttata	94.33	2.00e-157	547.00
IUUC-Tru-118014	Takifugu rubripes	74.88	5.00e-84	303.00
IUUC-Tsy-119326	Tarsius syrichta	78.77	5.00e-153	533.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	3.00e-81	295.00
IUUC-Tbe-128067	Tupaia belangeri	83.33	2.00e-145	508.00
IUUC-Ttr-128530	Tursiops truncatus	83.06	6.00e-141	493.00
IUUC-Vpa-130322	Vicugna pacos	84.17	1.00e-144	505.00
IUUC-Xtr-132606	Xenopus tropicalis	66.86	6.00e-117	413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence