iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003389

Ensembl Protein ID

ENSAPLP00000013124.1

UniProt Accession

U3J0U7; U3J0U7_ANAPL

Genbank Protein ID

ENSAPLP00000013124

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

ADON01071390

Gene Name

ABL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000013308.1	ENSAPLT00000013872.1	ENSAPLP00000013124.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-12	47.0	36	93

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 36   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 93
           67899************************.*********98..788899*********997 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

EALHRPYGCD VEPQALNEAI RWSSKENLLG ATESDPNLFV ALYDFVASGD NTLSITKGEK 60
LRVLGYNQNG EWSEVRSKNG QGWVPSNYIT PVNSLEKHSW YHGPVSRSAA EYLLSSLING 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCCCTGC ACCGCCCCTA TGGTTGCGAT GTTGAACCCC AGGCACTGAA CGAAGCCATC 60
AGGTGGAGCT CCAAGGAGAA CCTGCTTGGA GCCACTGAGA GCGATCCCAA CCTCTTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	86.47	0.00e+00	1764.00
IUUC-Aly-005867	Arabidopsis lyrata	28.68	6.00e-19	89.40
IUUC-Ath-006978	Arabidopsis thaliana	28.68	3.00e-19	90.10
IUUC-Ame-010629	Astyanax mexicanus	57.76	0.00e+00	1041.00
IUUC-Bta-013370	Bos taurus	86.47	0.00e+00	1749.00
IUUC-Cja-018894	Callithrix jacchus	86.36	0.00e+00	1766.00
IUUC-Cfa-020398	Canis familiaris	96.74	0.00e+00	1227.00
IUUC-Cpo-022367	Cavia porcellus	83.49	0.00e+00	1651.00
IUUC-Csa-023386	Chlorocebus sabaeus	86.29	0.00e+00	1764.00
IUUC-Cho-024714	Choloepus hoffmanni	91.68	0.00e+00	1305.00
IUUC-Dre-027741	Danio rerio	67.22	0.00e+00	1357.00
IUUC-Dno-029246	Dasypus novemcinctus	86.56	0.00e+00	1754.00
IUUC-Dor-030416	Dipodomys ordii	80.84	0.00e+00	1584.00
IUUC-Ete-032899	Echinops telfairi	63.66	0.00e+00	660.00
IUUC-Eca-033387	Equus caballus	86.29	0.00e+00	1728.00
IUUC-Eeu-035058	Erinaceus europaeus	78.27	0.00e+00	1623.00
IUUC-Fca-036578	Felis catus	80.58	0.00e+00	1585.00
IUUC-Fal-037491	Ficedula albicollis	93.10	0.00e+00	1961.00
IUUC-Gmo-038509	Gadus morhua	72.79	0.00e+00	1171.00
IUUC-Gga-040638	Gallus gallus	92.90	0.00e+00	1922.00
IUUC-Gac-042550	Gasterosteus aculeatus	68.95	0.00e+00	1340.00
IUUC-Gma-043938	Glycine max	28.42	1.00e-22	101.00
IUUC-Ggo-044487	Gorilla gorilla	86.02	0.00e+00	1757.00
IUUC-Hsa-046636	Homo sapiens	86.02	0.00e+00	1756.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	86.29	0.00e+00	1752.00
IUUC-Lch-049530	Latimeria chalumnae	77.31	0.00e+00	1545.00
IUUC-Lpe-051291	Leersia perrieri	31.05	1.00e-22	101.00
IUUC-Loc-051933	Lepisosteus oculatus	70.14	0.00e+00	1410.00
IUUC-Laf-053802	Loxodonta africana	86.23	0.00e+00	1794.00
IUUC-Mcc-054836	Macaca mulatta	86.74	0.00e+00	1781.00
IUUC-Mga-059277	Meleagris gallopavo	93.54	0.00e+00	1939.00
IUUC-Mmr-061206	Microcebus murinus	85.48	0.00e+00	1670.00
IUUC-Mdo-062281	Monodelphis domestica	80.60	0.00e+00	1585.00
IUUC-Mmu-063847	Mus musculus	84.76	0.00e+00	1659.00
IUUC-Mac-064649	Musa acuminata	33.17	2.00e-22	100.00
IUUC-Mpu-066309	Mustela putorius furo	96.09	0.00e+00	1220.00
IUUC-Mlu-068070	Myotis lucifugus	86.02	0.00e+00	1746.00
IUUC-Nle-070062	Nomascus leucogenys	96.42	0.00e+00	1224.00
IUUC-Opr-070534	Ochotona princeps	79.86	0.00e+00	888.00
IUUC-Ont-072440	Oreochromis niloticus	65.82	0.00e+00	1309.00
IUUC-Oan-073526	Ornithorhynchus anatinus	87.32	0.00e+00	1719.00
IUUC-Ocu-074051	Oryctolagus cuniculus	84.77	0.00e+00	1671.00
IUUC-Oba-074988	Oryza barthii	30.30	6.00e-19	89.40
IUUC-Oin-079172	Oryza indica	33.94	2.00e-23	104.00
IUUC-Olo-080286	Oryza longistaminata	33.94	1.00e-23	104.00
IUUC-Ome-081788	Oryza meridionalis	28.70	4.00e-27	115.00
IUUC-Oni-082734	Oryza nivara	33.64	2.00e-23	104.00
IUUC-Opu-083538	Oryza punctata	34.39	3.00e-23	103.00
IUUC-Oru-084741	Oryza rufipogon	33.94	1.00e-23	104.00
IUUC-Osa-085779	Oryza sativa	33.94	1.00e-23	104.00
IUUC-Ola-086752	Oryzias latipes	95.27	0.00e+00	917.00
IUUC-Oga-088767	Otolemur garnettii	80.31	0.00e+00	1563.00
IUUC-Oar-089800	Ovis aries	86.29	0.00e+00	1745.00
IUUC-Ptr-090857	Pan troglodytes	96.42	0.00e+00	1224.00
IUUC-Pan-092279	Papio anubis	86.20	0.00e+00	1761.00
IUUC-Psi-093573	Pelodiscus sinensis	90.49	0.00e+00	1831.00
IUUC-Pfo-096543	Poecilia formosa	65.44	0.00e+00	1259.00
IUUC-Pab-097949	Pongo abelii	86.02	0.00e+00	1716.00
IUUC-Pop-099554	Populus trichocarpa	32.00	5.00e-23	102.00
IUUC-Pca-100370	Procavia capensis	82.60	0.00e+00	1264.00
IUUC-Ppe-101625	Prunus persica	33.33	1.00e-20	95.10
IUUC-Pva-103220	Pteropus vampyrus	79.55	0.00e+00	1499.00
IUUC-Rno-105924	Rattus norvegicus	85.06	0.00e+00	1668.00
IUUC-Sha-107114	Sarcophilus harrisii	83.73	0.00e+00	1301.00
IUUC-Smo-109661	Selaginella moellendorffii	29.86	2.00e-23	102.00
IUUC-Sit-110219	Setaria italica	30.40	2.00e-21	97.40
IUUC-Sbi-114480	Sorghum bicolor	33.18	2.00e-24	107.00
IUUC-Ssc-115968	Sus scrofa	87.10	0.00e+00	1806.00
IUUC-Tgu-117301	Taeniopygia guttata	92.64	0.00e+00	1866.00
IUUC-Tru-118410	Takifugu rubripes	67.42	0.00e+00	1346.00
IUUC-Tni-119991	Tetraodon nigroviridis	67.92	0.00e+00	1342.00
IUUC-Tca-121389	Theobroma cacao	34.36	3.00e-24	107.00
IUUC-Tbe-127362	Tupaia belangeri	88.92	0.00e+00	1344.00
IUUC-Ttr-129291	Tursiops truncatus	86.38	0.00e+00	1763.00
IUUC-Vpa-130800	Vicugna pacos	87.94	0.00e+00	1385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence