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Tag Content
iUUCD ID IUUC-Ggo-044487
Ensembl Protein ID ENSGGOP00000002596.2
UniProt Accession G3QJK0; G3QJK0_GORGO
Protein Name Tyrosine-protein kinase
Gene Name ABL2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGGOG00000002631.2 ENSGGOT00000002648.2 ENSGGOP00000002594.2
ENSGGOG00000002631.2 ENSGGOT00000002650.2 ENSGGOP00000002596.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.70e-12 46.8 109 166
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 109  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 166
           67899************************.*********98..788899*********997 PP
   
Organism Gorilla gorilla
Protein Sequence
(Fasta)
MGQQVGRVGE APGLQQPQPR GIRGSSAARP SGRRRDPAGR TTETGFNIFT QHDHFASCVE 60
DGFEGDKTGG SSPEALHRPY GCDVEPQALN EAIRWSSKEN LLGATESDPN LFVALYDFVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ggo-044487|UBD,SH3|Gorilla gorilla
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGCAGC AGGTGGGCCG CGTCGGGGAA GCTCCGGGGC TCCAGCAGCC TCAGCCCCGC 60
GGGATCCGGG GCAGCAGTGC AGCCAGGCCC TCCGGCCGCA GGCGGGACCC GGCGGGGCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ggo-044487|UBD,SH3|Gorilla gorilla
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
KEGG ggo:101134626
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 96.84 0.00e+00 1994.00
IUUC-Apl-003389 Anas platyrhynchos 85.12 0.00e+00 1741.00
IUUC-Ame-010629 Astyanax mexicanus 58.31 0.00e+00 1077.00
IUUC-Bta-013370 Bos taurus 96.02 0.00e+00 2072.00
IUUC-Bdi-014324 Brachypodium distachyon 32.39 1.00e-22 101.00
IUUC-Cja-018894 Callithrix jacchus 96.49 0.00e+00 2029.00
IUUC-Cfa-020398 Canis familiaris 99.21 0.00e+00 1298.00
IUUC-Cpo-022367 Cavia porcellus 94.87 0.00e+00 1531.00
IUUC-Csa-023386 Chlorocebus sabaeus 99.19 0.00e+00 2050.00
IUUC-Cho-024714 Choloepus hoffmanni 91.88 0.00e+00 1880.00
IUUC-Dre-027741 Danio rerio 66.36 0.00e+00 1382.00
IUUC-Dno-029246 Dasypus novemcinctus 94.67 0.00e+00 2019.00
IUUC-Dor-030416 Dipodomys ordii 89.26 0.00e+00 1881.00
IUUC-Ete-032899 Echinops telfairi 76.93 0.00e+00 841.00
IUUC-Eca-033387 Equus caballus 96.85 0.00e+00 2007.00
IUUC-Eeu-035058 Erinaceus europaeus 84.95 0.00e+00 1858.00
IUUC-Fca-036578 Felis catus 89.69 0.00e+00 1801.00
IUUC-Fal-037491 Ficedula albicollis 88.04 0.00e+00 1873.00
IUUC-Gmo-038509 Gadus morhua 70.98 0.00e+00 1174.00
IUUC-Gga-040638 Gallus gallus 85.51 0.00e+00 1820.00
IUUC-Gac-042550 Gasterosteus aculeatus 78.16 0.00e+00 1181.00
IUUC-Hsa-046636 Homo sapiens 99.75 0.00e+00 2166.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 96.81 0.00e+00 2035.00
IUUC-Lch-049530 Latimeria chalumnae 75.27 0.00e+00 1588.00
IUUC-Loc-051933 Lepisosteus oculatus 69.72 0.00e+00 1432.00
IUUC-Laf-053802 Loxodonta africana 95.78 0.00e+00 2142.00
IUUC-Mcc-054836 Macaca mulatta 99.15 0.00e+00 2151.00
IUUC-Mga-059277 Meleagris gallopavo 87.76 0.00e+00 1836.00
IUUC-Mmr-061206 Microcebus murinus 96.02 0.00e+00 2049.00
IUUC-Mdo-062281 Monodelphis domestica 93.60 0.00e+00 1249.00
IUUC-Mmu-063847 Mus musculus 94.34 0.00e+00 1964.00
IUUC-Mpu-066309 Mustela putorius furo 98.54 0.00e+00 1397.00
IUUC-Mlu-068070 Myotis lucifugus 96.21 0.00e+00 1976.00
IUUC-Nle-070062 Nomascus leucogenys 99.85 0.00e+00 1366.00
IUUC-Opr-070534 Ochotona princeps 91.25 0.00e+00 1057.00
IUUC-Ont-072440 Oreochromis niloticus 64.12 0.00e+00 1350.00
IUUC-Oan-073526 Ornithorhynchus anatinus 88.58 0.00e+00 1766.00
IUUC-Ocu-074051 Oryctolagus cuniculus 95.23 0.00e+00 1888.00
IUUC-Ogl-077331 Oryza glaberrima 31.98 9.00e-23 102.00
IUUC-Ogu-078962 Oryza glumaepatula 33.94 6.00e-23 102.00
IUUC-Oin-079172 Oryza indica 33.94 5.00e-23 103.00
IUUC-Olo-080286 Oryza longistaminata 33.94 4.00e-23 103.00
IUUC-Oni-082734 Oryza nivara 33.64 4.00e-23 103.00
IUUC-Opu-083538 Oryza punctata 34.39 7.00e-23 102.00
IUUC-Oru-084741 Oryza rufipogon 33.94 3.00e-23 103.00
IUUC-Osa-085779 Oryza sativa 33.94 3.00e-23 103.00
IUUC-Oga-088767 Otolemur garnettii 91.19 0.00e+00 1806.00
IUUC-Oar-089800 Ovis aries 96.40 0.00e+00 1976.00
IUUC-Ptr-090857 Pan troglodytes 99.85 0.00e+00 1366.00
IUUC-Pan-092279 Papio anubis 97.38 0.00e+00 2089.00
IUUC-Psi-093573 Pelodiscus sinensis 88.51 0.00e+00 1811.00
IUUC-Pfo-096543 Poecilia formosa 71.69 0.00e+00 1156.00
IUUC-Pab-097949 Pongo abelii 97.80 0.00e+00 2062.00
IUUC-Pca-100370 Procavia capensis 94.55 0.00e+00 1467.00
IUUC-Pva-103220 Pteropus vampyrus 88.25 0.00e+00 1789.00
IUUC-Rno-105924 Rattus norvegicus 91.29 0.00e+00 1929.00
IUUC-Sha-107114 Sarcophilus harrisii 87.34 0.00e+00 1391.00
IUUC-Sit-110219 Setaria italica 30.30 7.00e-20 92.40
IUUC-Sbi-114480 Sorghum bicolor 32.27 3.00e-23 103.00
IUUC-Ssc-115968 Sus scrofa 96.02 0.00e+00 2130.00
IUUC-Tgu-117301 Taeniopygia guttata 87.60 0.00e+00 1794.00
IUUC-Tru-118410 Takifugu rubripes 65.87 0.00e+00 1404.00
IUUC-Tni-119991 Tetraodon nigroviridis 66.40 0.00e+00 1414.00
IUUC-Tbe-127362 Tupaia belangeri 91.71 0.00e+00 1895.00
IUUC-Ttr-129291 Tursiops truncatus 96.48 0.00e+00 1981.00
IUUC-Vpa-130800 Vicugna pacos 95.88 0.00e+00 1551.00
IUUC-Vvi-131181 Vitis vinifera 32.83 3.00e-21 97.40
IUUC-Xtr-132965 Xenopus tropicalis 67.99 0.00e+00 1444.00
Created Date 25-Jun-2017

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