iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067257

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02050513

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006230.2	ENSMLUT00000006232.2	ENSMLUP00000005690.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-42	140.0	515	547
UBD/Beta-Prp	3.70e-70	236.5	276	577

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+laf +d  l++s+s D+++++WD+r
   Q: 515  GHTDNITSLAFsPDsSLVASASMDNSVRIWDIR 547
           8***********9999***************87 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl.............................lrslsgheaevtavkfspdgkil 67
           h ++ +++  +spd++lla+g+++++ik+w+++++kl                             +++l gh ++v++++f  d++ l
   Q: 276  HTEQLLNAAEISPDGKLLAAGFDNSCIKLWSLRSKKLkaephqvdvsrirlacdaleeeeeeeeaeMKTLRGHCGPVYSTRFLADSSGL 364
           55667788899****************************************************************************** PP
   S: 68   vtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGs 156
           +++seD+ i+ wdl t++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + ++ + +gh + v cv++hp++n+l++Gs
   Q: 365  LSCSEDMSIRYWDLGTFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPVR-IYAGHLADVDCVRFHPNSNYLATGS 452
           ***************************************************************.************************* PP
   S: 157  lDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgs 245
           +D+tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s++fsp++ +++s+s+D+s
   Q: 453  TDKTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGSLYKELRGHTDNITSLAFSPDSSLVASASMDNS 540
           ********************9.******************************************************************* PP
   S: 246  iriWdlrsgdllktlqlhn...........ssvisva 271
           +riWd+r++ +  +  ++            s+v sv+
   Q: 541  VRIWDIRNSFCSAAADGSSgelvgvytgqmSNVLSVQ 577
           ****999999999999988444444444444444444 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDTDGPLK QGLRLSQTPE EMAANLTVQT ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSQ EVMPLLYPLF VYLHLHLVQN SPKSTAESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGGG TGCGCACGGA GCAGATTCAG ATGGCCGTGT CCTGCTACCT CAAACGCCGG 60
CAGTACGTGG ACACCGACGG TCCCCTGAAG CAAGGCCTGC GCCTGTCCCA GACGCCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	88.98	0.00e+00	1038.00
IUUC-Apl-003636	Anas platyrhynchos	84.69	0.00e+00	1043.00
IUUC-Aca-004229	Anolis carolinensis	83.31	0.00e+00	1001.00
IUUC-Ame-010599	Astyanax mexicanus	67.60	0.00e+00	806.00
IUUC-Bta-013404	Bos taurus	86.31	0.00e+00	984.00
IUUC-Cja-019643	Callithrix jacchus	88.48	0.00e+00	1035.00
IUUC-Cfa-020913	Canis familiaris	88.65	0.00e+00	1035.00
IUUC-Cpo-021777	Cavia porcellus	87.31	0.00e+00	1013.00
IUUC-Csa-024184	Chlorocebus sabaeus	88.31	0.00e+00	1034.00
IUUC-Cho-024638	Choloepus hoffmanni	87.31	0.00e+00	1019.00
IUUC-Cin-025618	Ciona intestinalis	34.05	1.00e-85	310.00
IUUC-Csv-025874	Ciona savignyi	42.47	6.00e-77	281.00
IUUC-Dre-028817	Danio rerio	67.16	0.00e+00	789.00
IUUC-Dno-029969	Dasypus novemcinctus	84.97	0.00e+00	999.00
IUUC-Dor-031117	Dipodomys ordii	86.64	0.00e+00	1040.00
IUUC-Ete-032712	Echinops telfairi	80.47	0.00e+00	921.00
IUUC-Eca-033742	Equus caballus	88.65	0.00e+00	1034.00
IUUC-Eeu-035096	Erinaceus europaeus	87.33	0.00e+00	1049.00
IUUC-Fca-035769	Felis catus	88.19	0.00e+00	1053.00
IUUC-Fal-036645	Ficedula albicollis	83.92	0.00e+00	977.00
IUUC-Fso-038302	Fusarium solani	33.77	6.00e-40	159.00
IUUC-Gmo-038636	Gadus morhua	68.55	0.00e+00	773.00
IUUC-Gga-040144	Gallus gallus	83.97	0.00e+00	1011.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.17	0.00e+00	802.00
IUUC-Ggo-044568	Gorilla gorilla	88.31	0.00e+00	1034.00
IUUC-Hsa-046178	Homo sapiens	88.31	0.00e+00	1034.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	84.81	0.00e+00	1036.00
IUUC-Lch-050501	Latimeria chalumnae	73.52	0.00e+00	827.00
IUUC-Loc-052895	Lepisosteus oculatus	79.89	6.00e-179	620.00
IUUC-Laf-053950	Loxodonta africana	85.98	0.00e+00	1008.00
IUUC-Mcc-055450	Macaca mulatta	88.15	0.00e+00	1030.00
IUUC-Meu-056182	Macropus eugenii	81.30	0.00e+00	956.00
IUUC-Mga-059619	Meleagris gallopavo	84.14	0.00e+00	1014.00
IUUC-Mmr-061074	Microcebus murinus	87.52	0.00e+00	1041.00
IUUC-Mdo-062307	Monodelphis domestica	86.33	0.00e+00	845.00
IUUC-Mmu-063226	Mus musculus	85.98	0.00e+00	1003.00
IUUC-Mpu-066016	Mustela putorius furo	88.31	0.00e+00	1030.00
IUUC-Nle-070139	Nomascus leucogenys	88.15	0.00e+00	1031.00
IUUC-Opr-070243	Ochotona princeps	83.47	0.00e+00	1005.00
IUUC-Ont-072686	Oreochromis niloticus	68.55	0.00e+00	823.00
IUUC-Oan-073670	Ornithorhynchus anatinus	80.59	0.00e+00	805.00
IUUC-Ocu-074525	Oryctolagus cuniculus	87.48	0.00e+00	1048.00
IUUC-Ola-086524	Oryzias latipes	68.22	0.00e+00	826.00
IUUC-Oga-088540	Otolemur garnettii	87.81	0.00e+00	1023.00
IUUC-Oar-089793	Ovis aries	82.64	0.00e+00	919.00
IUUC-Ptr-091154	Pan troglodytes	88.31	0.00e+00	1034.00
IUUC-Pan-092759	Papio anubis	88.15	0.00e+00	1030.00
IUUC-Psi-094008	Pelodiscus sinensis	81.80	0.00e+00	1000.00
IUUC-Pma-094593	Petromyzon marinus	46.48	3.00e-132	465.00
IUUC-Pfo-097409	Poecilia formosa	68.39	0.00e+00	804.00
IUUC-Pab-097946	Pongo abelii	77.46	0.00e+00	882.00
IUUC-Pca-100727	Procavia capensis	81.14	0.00e+00	930.00
IUUC-Pva-103211	Pteropus vampyrus	82.94	0.00e+00	986.00
IUUC-Ptt-103995	Puccinia triticina	45.89	6.00e-69	256.00
IUUC-Rno-105236	Rattus norvegicus	86.14	0.00e+00	994.00
IUUC-Sha-106833	Sarcophilus harrisii	86.71	0.00e+00	1036.00
IUUC-Sar-113381	Sorex araneus	88.31	0.00e+00	1060.00
IUUC-Ssc-116421	Sus scrofa	87.48	0.00e+00	1063.00
IUUC-Tgu-117143	Taeniopygia guttata	84.64	0.00e+00	1042.00
IUUC-Tru-118680	Takifugu rubripes	67.61	0.00e+00	820.00
IUUC-Tsy-119622	Tarsius syrichta	72.58	0.00e+00	779.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.17	0.00e+00	818.00
IUUC-Tbe-127656	Tupaia belangeri	80.65	6.00e-74	271.00
IUUC-Ttr-129171	Tursiops truncatus	86.81	0.00e+00	1003.00
IUUC-Xtr-132241	Xenopus tropicalis	77.05	0.00e+00	913.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence