iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-094008

Ensembl Protein ID

ENSPSIP00000002790.1

UniProt Accession

K7F430; K7F430_PELSI

Genbank Protein ID

ENSPSIP00000002790

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01078516

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000002719.1	ENSPSIT00000002801.1	ENSPSIP00000002790.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-31	107.5	504	536
UBD/Beta-Prp	2.00e-60	204.5	271	556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++s+s D++i+vWD+r
   Q: 504  GHTDNITSLTFsPDsSLIASASMDNSIRVWDIR 536
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g++++++k+w++++ kl                                ++ l gh ++v++++f +d++ l++
   Q: 271  LNTAEISPDSKLLAAGFDNSCVKLWSLRSRKLksephlvdvsrihlacdvvdeeeeddnnvgteMKILRGHCGPVYSTRFLSDSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp + +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPWSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v  l+f++ngk          +klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+sir
   Q: 448  KTVRLWSTQQGNSVRLFTG-HRGPVLALAFSPNGKX----XXXXXLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASASMDNSIR 531
           ******************9.*************965....67789******************************************** PP
   S: 248  iWdlrsgdllktlqlhnssvisvav 272
           +Wd+r+  ++    ++ s ++ v +
   Q: 532  VWDIRNTYCNAPADGSSSELVGVYT 556
           **99999998888887755555554 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MKRARTEQIQ MAVSCYLKRR QYVDSEGPLK QGLRLCQSTE EMAANLTVQA ESGCANVVSA 60
APCLAEPQQY EVQFGRLRSF LTDSDSQHSH EVMPLLYPLF VYLHLNMVQN GLKSTVDSFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCTGCCCC CACAGAAGCT GTGGGACTCA CACTGCAACA TGGCTAGCTG GTTGGGATGC 60
CACCTGCCTG GGACGTGGGT TCCTGTTAAC CAGTTACTTC TCCGGTAAAA CTAAGGCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

KEGG

pss:102445421

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	89.81	0.00e+00	1026.00
IUUC-Apl-003636	Anas platyrhynchos	93.06	0.00e+00	1120.00
IUUC-Aca-004229	Anolis carolinensis	91.85	0.00e+00	1087.00
IUUC-Ame-010599	Astyanax mexicanus	65.73	0.00e+00	798.00
IUUC-Bta-013404	Bos taurus	86.59	0.00e+00	981.00
IUUC-Cja-019643	Callithrix jacchus	89.64	0.00e+00	1045.00
IUUC-Cfa-020913	Canis familiaris	89.98	0.00e+00	1045.00
IUUC-Cpo-021777	Cavia porcellus	87.95	0.00e+00	1005.00
IUUC-Csa-024184	Chlorocebus sabaeus	89.64	0.00e+00	1046.00
IUUC-Cho-024638	Choloepus hoffmanni	89.64	0.00e+00	1021.00
IUUC-Cin-025618	Ciona intestinalis	33.33	5.00e-83	301.00
IUUC-Csv-025874	Ciona savignyi	32.65	2.00e-83	302.00
IUUC-Dre-028817	Danio rerio	65.61	0.00e+00	776.00
IUUC-Dno-029969	Dasypus novemcinctus	82.34	0.00e+00	981.00
IUUC-Dor-031117	Dipodomys ordii	88.12	0.00e+00	1031.00
IUUC-Ete-032712	Echinops telfairi	82.51	0.00e+00	920.00
IUUC-Eca-033742	Equus caballus	90.15	0.00e+00	1050.00
IUUC-Eeu-035096	Erinaceus europaeus	87.29	0.00e+00	1048.00
IUUC-Fca-035769	Felis catus	89.17	0.00e+00	1061.00
IUUC-Fal-036645	Ficedula albicollis	93.53	0.00e+00	1060.00
IUUC-Gmo-038636	Gadus morhua	63.83	0.00e+00	759.00
IUUC-Gga-040144	Gallus gallus	93.04	0.00e+00	1094.00
IUUC-Gac-041716	Gasterosteus aculeatus	66.72	0.00e+00	784.00
IUUC-Ggo-044568	Gorilla gorilla	89.81	0.00e+00	1046.00
IUUC-Hsa-046178	Homo sapiens	89.81	0.00e+00	1046.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	83.19	0.00e+00	1011.00
IUUC-Lch-050501	Latimeria chalumnae	76.95	0.00e+00	853.00
IUUC-Loc-052895	Lepisosteus oculatus	79.57	2.00e-176	612.00
IUUC-Laf-053950	Loxodonta africana	86.59	0.00e+00	998.00
IUUC-Mcc-055450	Macaca mulatta	89.64	0.00e+00	1042.00
IUUC-Meu-056182	Macropus eugenii	87.27	0.00e+00	986.00
IUUC-Mga-059619	Meleagris gallopavo	93.21	0.00e+00	1097.00
IUUC-Mmr-061074	Microcebus murinus	88.83	0.00e+00	1056.00
IUUC-Mdo-062307	Monodelphis domestica	93.33	0.00e+00	888.00
IUUC-Mmu-063226	Mus musculus	86.25	0.00e+00	995.00
IUUC-Mpu-066016	Mustela putorius furo	89.64	0.00e+00	1022.00
IUUC-Mlu-067257	Myotis lucifugus	81.80	0.00e+00	1000.00
IUUC-Nle-070139	Nomascus leucogenys	89.98	0.00e+00	1048.00
IUUC-Opr-070243	Ochotona princeps	85.91	0.00e+00	1007.00
IUUC-Ont-072686	Oreochromis niloticus	67.89	0.00e+00	817.00
IUUC-Oan-073670	Ornithorhynchus anatinus	80.68	0.00e+00	818.00
IUUC-Ocu-074525	Oryctolagus cuniculus	88.79	0.00e+00	1042.00
IUUC-Ola-086524	Oryzias latipes	67.05	0.00e+00	827.00
IUUC-Oga-088540	Otolemur garnettii	89.47	0.00e+00	1043.00
IUUC-Oar-089793	Ovis aries	84.04	0.00e+00	920.00
IUUC-Ptr-091154	Pan troglodytes	89.81	0.00e+00	1046.00
IUUC-Pan-092759	Papio anubis	89.64	0.00e+00	1042.00
IUUC-Pma-094593	Petromyzon marinus	44.92	3.00e-125	441.00
IUUC-Pfo-097409	Poecilia formosa	65.89	0.00e+00	791.00
IUUC-Pab-097946	Pongo abelii	79.29	0.00e+00	899.00
IUUC-Pca-100727	Procavia capensis	83.19	0.00e+00	929.00
IUUC-Pva-103211	Pteropus vampyrus	78.95	0.00e+00	946.00
IUUC-Rno-105236	Rattus norvegicus	86.76	0.00e+00	979.00
IUUC-Sha-106833	Sarcophilus harrisii	91.22	0.00e+00	1063.00
IUUC-Sar-113381	Sorex araneus	90.15	0.00e+00	1076.00
IUUC-Ssc-116421	Sus scrofa	87.95	0.00e+00	1061.00
IUUC-Tgu-117143	Taeniopygia guttata	94.06	0.00e+00	1126.00
IUUC-Tru-118680	Takifugu rubripes	66.83	0.00e+00	815.00
IUUC-Tsy-119622	Tarsius syrichta	75.72	0.00e+00	787.00
IUUC-Tni-120131	Tetraodon nigroviridis	65.72	0.00e+00	810.00
IUUC-Tbe-127656	Tupaia belangeri	87.86	1.00e-80	293.00
IUUC-Ttr-129171	Tursiops truncatus	86.93	0.00e+00	996.00
IUUC-Xtr-132241	Xenopus tropicalis	79.49	0.00e+00	935.00
IUUC-Xma-133554	Xiphophorus maculatus	66.73	0.00e+00	728.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence