iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111259

Ensembl Protein ID

Solyc05g050580.2.1

UniProt Accession

K4C190; K4C190_SOLLC

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc05g050580.2	Solyc05g050580.2.1	Solyc05g050580.2.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	38.04	7.00e-40	162.00	IUUC-Hsa-046357
E3 activity/RING/RING	36.76	3.00e-40	162.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Solanum lycopersicum

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MELDSIECVS SSDGMIDDDE IPLHHPHIIH SQYSSSKTSN NNNINNSSSN NDGIAAIHST 60
TSVHELLECP VCTNSMYPPI HQCHNGHTIC STCKARAHNR CPTCRQELGD IRCLALEKVA 120

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Nucleotide Sequence
(Fasta)

AGCAGAAGCT TAAAGGTTTC TGTCTCTCTT CTCTTGTCTC TTCAATCTCT GAATCAAAAA 60
CAATGATTTG AAAAAGAAAA TGAAGATTGA TGGAAACCCA TCAACAAATT CCCTCAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sly:101246723

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	77.57	4.00e-125	439.00
IUUC-Aml-001186	Ailuropoda melanoleuca	36.76	1.00e-41	162.00
IUUC-Atr-003118	Amborella trichopoda	82.38	9.00e-133	465.00
IUUC-Apl-003813	Anas platyrhynchos	38.04	1.00e-41	162.00
IUUC-Aca-005014	Anolis carolinensis	36.76	1.00e-41	162.00
IUUC-Aly-006522	Arabidopsis lyrata	75.68	1.00e-147	514.00
IUUC-Ath-007092	Arabidopsis thaliana	79.76	2.00e-153	534.00
IUUC-Ame-011196	Astyanax mexicanus	36.76	7.00e-42	163.00
IUUC-Bta-012887	Bos taurus	36.76	1.00e-41	162.00
IUUC-Bdi-014729	Brachypodium distachyon	76.92	2.00e-151	527.00
IUUC-Bol-015983	Brassica oleracea	84.59	9.00e-147	511.00
IUUC-Bra-017336	Brassica rapa	79.06	1.00e-147	514.00
IUUC-Cel-018320	Caenorhabditis elegans	33.33	7.00e-37	147.00
IUUC-Cja-019796	Callithrix jacchus	36.76	2.00e-41	162.00
IUUC-Cfa-020642	Canis familiaris	38.04	9.00e-42	162.00
IUUC-Cpo-022348	Cavia porcellus	36.76	1.00e-41	162.00
IUUC-Csa-023974	Chlorocebus sabaeus	36.76	2.00e-41	162.00
IUUC-Cho-024933	Choloepus hoffmanni	35.22	1.00e-37	149.00
IUUC-Dre-028041	Danio rerio	36.76	6.00e-42	163.00
IUUC-Dno-029764	Dasypus novemcinctus	38.04	2.00e-41	162.00
IUUC-Dor-030489	Dipodomys ordii	32.43	6.00e-20	89.40
IUUC-Ete-032423	Echinops telfairi	37.24	1.00e-40	159.00
IUUC-Eca-033536	Equus caballus	38.04	1.00e-41	162.00
IUUC-Eeu-035314	Erinaceus europaeus	37.24	9.00e-41	159.00
IUUC-Fca-035362	Felis catus	36.76	1.00e-41	162.00
IUUC-Fal-037487	Ficedula albicollis	38.04	1.00e-41	162.00
IUUC-Gmo-039091	Gadus morhua	36.03	1.00e-36	146.00
IUUC-Gga-040269	Gallus gallus	38.04	1.00e-41	162.00
IUUC-Gac-042282	Gasterosteus aculeatus	36.76	4.00e-42	164.00
IUUC-Gma-042926	Glycine max	83.33	3.00e-133	466.00
IUUC-Ggo-045444	Gorilla gorilla	36.76	2.00e-41	162.00
IUUC-Hsa-046357	Homo sapiens	36.76	2.00e-41	162.00
IUUC-Hvu-047574	Hordeum vulgare	77.57	3.00e-125	440.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.76	1.00e-41	162.00
IUUC-Lch-049504	Latimeria chalumnae	36.76	1.00e-41	162.00
IUUC-Lpe-050879	Leersia perrieri	79.92	1.00e-124	438.00
IUUC-Loc-052191	Lepisosteus oculatus	36.76	1.00e-41	162.00
IUUC-Laf-053668	Loxodonta africana	38.04	1.00e-41	162.00
IUUC-Mcc-054640	Macaca mulatta	36.76	2.00e-41	162.00
IUUC-Meu-055922	Macropus eugenii	34.82	4.00e-36	144.00
IUUC-Mtr-058699	Medicago truncatula	81.27	3.00e-155	540.00
IUUC-Mga-059503	Meleagris gallopavo	36.76	1.00e-41	162.00
IUUC-Mmr-060794	Microcebus murinus	36.76	1.00e-41	162.00
IUUC-Mdo-061971	Monodelphis domestica	35.63	6.00e-38	150.00
IUUC-Mmu-064129	Mus musculus	36.76	9.00e-42	162.00
IUUC-Mac-065670	Musa acuminata	80.66	6.00e-157	545.00
IUUC-Mpu-066331	Mustela putorius furo	36.40	1.00e-41	162.00
IUUC-Mlu-067207	Myotis lucifugus	36.76	1.00e-41	162.00
IUUC-Nle-069706	Nomascus leucogenys	36.76	2.00e-41	162.00
IUUC-Opr-070341	Ochotona princeps	27.22	2.00e-11	62.40
IUUC-Ont-071849	Oreochromis niloticus	36.76	4.00e-42	164.00
IUUC-Ocu-074876	Oryctolagus cuniculus	36.76	2.00e-41	162.00
IUUC-Oba-075289	Oryza barthii	89.76	3.00e-138	483.00
IUUC-Obr-076037	Oryza brachyantha	80.46	6.00e-131	459.00
IUUC-Ogl-077148	Oryza glaberrima	81.40	5.00e-131	459.00
IUUC-Ogu-078042	Oryza glumaepatula	81.40	3.00e-131	460.00
IUUC-Oin-079325	Oryza indica	81.40	5.00e-131	459.00
IUUC-Olo-080244	Oryza longistaminata	82.03	2.00e-131	461.00
IUUC-Ome-081318	Oryza meridionalis	80.71	1.00e-124	437.00
IUUC-Oni-082163	Oryza nivara	81.40	5.00e-131	459.00
IUUC-Opu-084065	Oryza punctata	80.31	3.00e-124	437.00
IUUC-Oru-084833	Oryza rufipogon	81.40	5.00e-131	459.00
IUUC-Osa-085316	Oryza sativa	81.40	5.00e-131	459.00
IUUC-Ola-086814	Oryzias latipes	36.76	4.00e-42	164.00
IUUC-Oga-088114	Otolemur garnettii	38.49	7.00e-44	169.00
IUUC-Oar-089323	Ovis aries	36.76	1.00e-41	162.00
IUUC-Ptr-090692	Pan troglodytes	36.76	1.00e-41	162.00
IUUC-Pan-092012	Papio anubis	36.76	2.00e-41	162.00
IUUC-Psi-093687	Pelodiscus sinensis	38.04	1.00e-41	162.00
IUUC-Pma-094387	Petromyzon marinus	36.36	2.00e-41	161.00
IUUC-Ppa-095212	Physcomitrella patens	85.27	9.00e-137	478.00
IUUC-Pfo-097134	Poecilia formosa	36.76	4.00e-42	164.00
IUUC-Pab-097555	Pongo abelii	36.76	2.00e-41	162.00
IUUC-Pop-100033	Populus trichocarpa	79.88	7.00e-154	535.00
IUUC-Pca-100328	Procavia capensis	34.41	1.00e-34	139.00
IUUC-Ppe-101960	Prunus persica	81.14	1.00e-158	551.00
IUUC-Pva-103132	Pteropus vampyrus	27.08	3.00e-10	57.80
IUUC-Rno-104866	Rattus norvegicus	36.76	9.00e-42	162.00
IUUC-Sha-106547	Sarcophilus harrisii	38.04	2.00e-41	162.00
IUUC-Smo-109412	Selaginella moellendorffii	86.77	1.00e-138	484.00
IUUC-Sit-110245	Setaria italica	81.23	5.00e-131	459.00
IUUC-Stu-112571	Solanum tuberosum	96.70	0.00e+00	641.00
IUUC-Sbi-114035	Sorghum bicolor	81.61	3.00e-132	463.00
IUUC-Ssc-116441	Sus scrofa	35.22	2.00e-37	148.00
IUUC-Tgu-116579	Taeniopygia guttata	38.04	1.00e-41	162.00
IUUC-Tru-118250	Takifugu rubripes	35.97	2.00e-40	158.00
IUUC-Tsy-119548	Tarsius syrichta	29.06	1.00e-07	49.30
IUUC-Tni-120488	Tetraodon nigroviridis	36.36	6.00e-39	153.00
IUUC-Tca-121517	Theobroma cacao	81.12	4.00e-158	549.00
IUUC-Tae-123647	Triticum aestivum	77.57	4.00e-125	439.00
IUUC-Tur-126259	Triticum urartu	80.46	5.00e-130	456.00
IUUC-Ttr-129166	Tursiops truncatus	36.82	3.00e-39	154.00
IUUC-Vpa-130799	Vicugna pacos	31.40	4.00e-18	83.20
IUUC-Xtr-132553	Xenopus tropicalis	36.76	9.00e-42	162.00
IUUC-Xma-133670	Xiphophorus maculatus	36.76	4.00e-42	164.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence