iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106962

Ensembl Protein ID

ENSSHAP00000012396.1

UniProt Accession

G3WAE1; G3WAE1_SARHA

Genbank Protein ID

ENSSHAP00000012396

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

AEFK01127626

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010618.1	ENSSHAT00000012498.1	ENSSHAP00000012396.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	1.80e-19	68.9	1017	1045

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+QeE++a+++q +
   Q: 1017 AFSQVDPEVFAALPAELQEELKAAYDQKQ 1045
           59************************987 PP

Organism

Sarcophilus harrisii

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRT ENDGWRKWGG YMAAKVQKLE EQFRSDAGLQ KDGTSTIFSG VAIYVNGYTD 60
PSAEELRKLM MLHGGQYHVY YSRSKTTHII ATNLTNAKIR ELKGEKVIRP EWIVESIKAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCGAG GTGGATGGAG GAAACGAACT GAAAATGATG GCTGGAGGAA ATGGGTGTGT 60
TTAAGTACAA TTTATTTTGT AACTTTTTCA ACAATCTCAA CAATTGTTCT GAGTTTCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	31.08	2.00e-31	131.00
IUUC-Aml-001185	Ailuropoda melanoleuca	81.65	0.00e+00	2004.00
IUUC-Atr-002915	Amborella trichopoda	29.53	1.00e-102	367.00
IUUC-Apl-004054	Anas platyrhynchos	77.61	0.00e+00	1870.00
IUUC-Aca-004304	Anolis carolinensis	70.35	0.00e+00	1731.00
IUUC-Aly-005696	Arabidopsis lyrata	34.95	1.00e-86	314.00
IUUC-Ath-006893	Arabidopsis thaliana	34.49	3.00e-87	317.00
IUUC-Ago-007722	Ashbya gossypii	32.46	1.00e-35	144.00
IUUC-Acl-008347	Aspergillus clavatus	36.43	2.00e-84	307.00
IUUC-Afl-008444	Aspergillus flavus	37.35	6.00e-86	312.00
IUUC-Afu-008837	Aspergillus fumigatus	36.27	2.00e-83	304.00
IUUC-Ani-009188	Aspergillus nidulans	37.70	2.00e-91	330.00
IUUC-Ang-009866	Aspergillus niger	33.94	5.00e-97	349.00
IUUC-Aor-010107	Aspergillus oryzae	37.35	7.00e-86	312.00
IUUC-Ate-010359	Aspergillus terreus	32.27	6.00e-90	325.00
IUUC-Ame-010664	Astyanax mexicanus	50.26	0.00e+00	1139.00
IUUC-Bgr-012244	Blumeria graminis	30.62	1.00e-81	298.00
IUUC-Bta-013405	Bos taurus	74.63	0.00e+00	1704.00
IUUC-Bci-013849	Botrytis cinerea	30.80	2.00e-85	311.00
IUUC-Bdi-014066	Brachypodium distachyon	37.34	1.00e-86	314.00
IUUC-Bol-015544	Brassica oleracea	31.20	9.00e-89	321.00
IUUC-Bra-017792	Brassica rapa	35.56	7.00e-83	302.00
IUUC-Cel-018148	Caenorhabditis elegans	34.05	6.00e-85	308.00
IUUC-Cja-019742	Callithrix jacchus	72.32	0.00e+00	1451.00
IUUC-Cfa-020112	Canis familiaris	82.20	0.00e+00	2029.00
IUUC-Cpo-022152	Cavia porcellus	77.59	0.00e+00	1959.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	43.95	1.00e-39	158.00
IUUC-Csa-023504	Chlorocebus sabaeus	82.36	0.00e+00	2023.00
IUUC-Cho-024780	Choloepus hoffmanni	62.61	0.00e+00	691.00
IUUC-Cin-025276	Ciona intestinalis	52.37	6.00e-102	364.00
IUUC-Csv-026283	Ciona savignyi	43.95	1.00e-116	414.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	28.12	3.00e-88	320.00
IUUC-Cne-027079	Cryptococcus neoformans	34.64	2.00e-78	288.00
IUUC-Cme-027346	Cyanidioschyzon merolae	27.27	3.00e-40	160.00
IUUC-Dre-028073	Danio rerio	49.78	0.00e+00	1091.00
IUUC-Dno-030038	Dasypus novemcinctus	78.61	0.00e+00	1952.00
IUUC-Dor-031100	Dipodomys ordii	77.92	0.00e+00	1426.00
IUUC-Dse-031310	Dothistroma septosporum	32.91	2.00e-77	284.00
IUUC-Dme-031991	Drosophila melanogaster	40.60	3.00e-110	392.00
IUUC-Ete-033082	Echinops telfairi	73.37	0.00e+00	1350.00
IUUC-Eca-033471	Equus caballus	81.88	0.00e+00	2008.00
IUUC-Eeu-034993	Erinaceus europaeus	80.67	0.00e+00	1345.00
IUUC-Fca-035367	Felis catus	81.36	0.00e+00	1955.00
IUUC-Fal-036973	Ficedula albicollis	76.72	0.00e+00	1794.00
IUUC-Fox-037677	Fusarium oxysporum	33.75	1.00e-81	298.00
IUUC-Fso-038252	Fusarium solani	35.71	7.00e-84	305.00
IUUC-Gmo-039669	Gadus morhua	52.97	0.00e+00	841.00
IUUC-Ggr-039988	Gaeumannomyces graminis	42.32	2.00e-75	277.00
IUUC-Gga-040423	Gallus gallus	77.30	0.00e+00	1857.00
IUUC-Gac-042134	Gasterosteus aculeatus	53.34	0.00e+00	829.00
IUUC-Gma-042929	Glycine max	32.67	6.00e-91	328.00
IUUC-Ggo-044528	Gorilla gorilla	82.36	0.00e+00	2023.00
IUUC-Hsa-046259	Homo sapiens	82.44	0.00e+00	2006.00
IUUC-Hvu-047139	Hordeum vulgare	35.68	7.00e-54	204.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	81.16	0.00e+00	1999.00
IUUC-Kpa-049169	Komagataella pastoris	29.76	2.00e-64	240.00
IUUC-Lch-050471	Latimeria chalumnae	65.62	0.00e+00	1553.00
IUUC-Lpe-050800	Leersia perrieri	32.73	6.00e-91	328.00
IUUC-Loc-052320	Lepisosteus oculatus	46.33	0.00e+00	910.00
IUUC-Lma-053149	Leptosphaeria maculans	27.28	9.00e-89	322.00
IUUC-Laf-053810	Loxodonta africana	78.09	0.00e+00	1869.00
IUUC-Mcc-055574	Macaca mulatta	82.52	0.00e+00	1995.00
IUUC-Meu-055945	Macropus eugenii	75.95	0.00e+00	1355.00
IUUC-Mor-057195	Magnaporthe oryzae	30.06	8.00e-90	325.00
IUUC-Mpo-057488	Magnaporthe poae	34.83	6.00e-85	309.00
IUUC-Mtr-057955	Medicago truncatula	34.91	2.00e-87	317.00
IUUC-Mla-059027	Melampsora laricipopulina	36.72	1.00e-81	297.00
IUUC-Mga-060156	Meleagris gallopavo	77.14	0.00e+00	1864.00
IUUC-Mvi-060398	Microbotryum violaceum	36.61	2.00e-82	301.00
IUUC-Mmr-061113	Microcebus murinus	82.36	0.00e+00	2013.00
IUUC-Mdo-063001	Monodelphis domestica	93.11	0.00e+00	2262.00
IUUC-Mmu-063180	Mus musculus	77.55	0.00e+00	1882.00
IUUC-Mac-065551	Musa acuminata	40.00	4.00e-54	206.00
IUUC-Mpu-066525	Mustela putorius furo	82.36	0.00e+00	2022.00
IUUC-Mlu-067877	Myotis lucifugus	80.22	0.00e+00	1959.00
IUUC-Nfi-068418	Neosartorya fischeri	31.87	1.00e-84	308.00
IUUC-Ncr-068648	Neurospora crassa	31.07	6.00e-88	319.00
IUUC-Nle-069959	Nomascus leucogenys	82.42	0.00e+00	2010.00
IUUC-Opr-070522	Ochotona princeps	78.02	0.00e+00	1137.00
IUUC-Ont-072293	Oreochromis niloticus	49.57	0.00e+00	833.00
IUUC-Oan-073519	Ornithorhynchus anatinus	79.76	0.00e+00	1984.00
IUUC-Ocu-074492	Oryctolagus cuniculus	78.79	0.00e+00	1831.00
IUUC-Oba-075567	Oryza barthii	33.23	4.00e-91	329.00
IUUC-Obr-076332	Oryza brachyantha	37.60	7.00e-87	315.00
IUUC-Ogl-077348	Oryza glaberrima	33.23	7.00e-91	328.00
IUUC-Ogu-078779	Oryza glumaepatula	33.08	2.00e-90	327.00
IUUC-Oin-079738	Oryza indica	30.62	7.00e-79	288.00
IUUC-Olo-080701	Oryza longistaminata	30.77	2.00e-79	290.00
IUUC-Ome-081708	Oryza meridionalis	33.13	2.00e-88	320.00
IUUC-Oni-082251	Oryza nivara	32.77	5.00e-88	319.00
IUUC-Opu-083528	Oryza punctata	31.98	1.00e-83	305.00
IUUC-Oru-084293	Oryza rufipogon	32.46	6.00e-86	312.00
IUUC-Osa-085549	Oryza sativa	33.23	1.00e-90	328.00
IUUC-Ola-086793	Oryzias latipes	49.51	0.00e+00	858.00
IUUC-Olu-087786	Ostreococcus lucimarinus	28.05	1.00e-59	224.00
IUUC-Oga-089006	Otolemur garnettii	81.58	0.00e+00	1988.00
IUUC-Oar-089597	Ovis aries	76.27	0.00e+00	1862.00
IUUC-Ptr-091520	Pan troglodytes	82.44	0.00e+00	2005.00
IUUC-Pan-092333	Papio anubis	82.28	0.00e+00	1985.00
IUUC-Psi-094004	Pelodiscus sinensis	80.53	0.00e+00	1956.00
IUUC-Pma-094128	Petromyzon marinus	53.04	1.00e-94	340.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.91	1.00e-75	278.00
IUUC-Ppa-095714	Physcomitrella patens	27.82	1.00e-93	337.00
IUUC-Pfo-096569	Poecilia formosa	47.79	0.00e+00	1009.00
IUUC-Pab-097960	Pongo abelii	82.20	0.00e+00	1999.00
IUUC-Pop-098921	Populus trichocarpa	31.29	2.00e-105	377.00
IUUC-Pca-100509	Procavia capensis	66.10	0.00e+00	1148.00
IUUC-Ppe-101730	Prunus persica	31.77	1.00e-92	334.00
IUUC-Pva-102142	Pteropus vampyrus	79.03	0.00e+00	1914.00
IUUC-Pgr-103446	Puccinia graminis	32.82	3.00e-71	263.00
IUUC-Ptt-103849	Puccinia triticina	31.08	2.00e-74	275.00
IUUC-Pte-104128	Pyrenophora teres	34.31	5.00e-76	279.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	39.27	9.00e-73	268.00
IUUC-Rno-104871	Rattus norvegicus	75.32	0.00e+00	1855.00
IUUC-Sce-106236	Saccharomyces cerevisiae	27.88	2.00e-41	164.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	33.61	2.00e-63	237.00
IUUC-Spo-108170	Schizosaccharomyces pombe	34.29	4.00e-66	246.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	35.09	9.00e-86	311.00
IUUC-Smo-109554	Selaginella moellendorffii	36.44	5.00e-86	312.00
IUUC-Sit-110479	Setaria italica	35.15	3.00e-72	266.00
IUUC-Sly-111752	Solanum lycopersicum	36.35	2.00e-91	330.00
IUUC-Sar-113304	Sorex araneus	79.40	0.00e+00	1889.00
IUUC-Sbi-114196	Sorghum bicolor	42.38	3.00e-72	266.00
IUUC-Sre-115151	Sporisorium reilianum	32.16	6.00e-88	319.00
IUUC-Ssc-116104	Sus scrofa	79.97	0.00e+00	1968.00
IUUC-Tgu-117438	Taeniopygia guttata	78.08	0.00e+00	1851.00
IUUC-Tru-118553	Takifugu rubripes	48.20	0.00e+00	990.00
IUUC-Tsy-119056	Tarsius syrichta	77.88	0.00e+00	1834.00
IUUC-Tni-119933	Tetraodon nigroviridis	47.47	0.00e+00	974.00
IUUC-Tca-121376	Theobroma cacao	31.07	3.00e-87	317.00
IUUC-Tre-121972	Trichoderma reesei	42.01	2.00e-72	267.00
IUUC-Tvi-122342	Trichoderma virens	29.48	1.00e-85	311.00
IUUC-Tae-123898	Triticum aestivum	33.03	2.00e-85	310.00
IUUC-Tur-126735	Triticum urartu	30.84	9.00e-37	149.00
IUUC-Tme-126999	Tuber melanosporum	33.78	6.00e-83	303.00
IUUC-Tbe-127280	Tupaia belangeri	77.50	8.00e-119	421.00
IUUC-Ttr-129104	Tursiops truncatus	79.13	0.00e+00	1924.00
IUUC-Uma-129562	Ustilago maydis	29.53	5.00e-86	313.00
IUUC-Vda-129862	Verticillium dahliae	41.72	4.00e-76	280.00
IUUC-Vpa-130819	Vicugna pacos	79.54	0.00e+00	1051.00
IUUC-Vvi-131111	Vitis vinifera	34.99	6.00e-87	315.00
IUUC-Xtr-132629	Xenopus tropicalis	62.46	0.00e+00	1433.00
IUUC-Xma-134065	Xiphophorus maculatus	49.75	0.00e+00	813.00
IUUC-Yli-134633	Yarrowia lipolytica	33.33	2.00e-61	231.00
IUUC-Zma-135176	Zea mays	33.13	1.00e-88	321.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence