iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000009637.2	ENSPANT00000000370.2	ENSPANP00000003560.1
ENSPANG00000009637.2	ENSPANT00000000371.1	ENSPANP00000001748.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.00e-08	34.1	413	474

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..............kdgpl......vlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC+e++                  +      +++CgH++h+ Cl ++ +++ ++ ++ +CP+C+
   Q: 413  CTICMERLvtasgyegvlrhkgV---RpelvgrLGRCGHMYHLLCLVAM-YSNGNKDGSLQCPTCK 474
           9*******888876666654331...2333333799**********666.79999**********6 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MSRPGHGGLM PVNGLGFPPQ NVARVVVWEW LNEHSRWRPY TATVCHHIEN VLKEDARGSV 60
VLGQVDAQLV PYIIDLQSMH QFRQDTGTMR PVRRNFYDPS SAPGKGIVWE WENDGGAWTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCGCGAGCA CGAGTGGGGT GGGGCGTGCC CACGGGCCCC CGCCCCCCTC GTCCCCCTCG 60
TCCCCCAGCC CAGCTCCGGA GCCGCAGTCC AGGCGCACCC CCCGGGGGTC CGCGCCGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50918--WWE
PS50089--ZF_RING_2

Pfam

PF02825--WWE
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0008270--F:zinc ion binding
GO:0010001--P:glial cell differentiation
GO:0045665--P:negative regulation of neuron differentiation
GO:0045581--P:negative regulation of T cell differentiation
GO:0007219--P:Notch signaling pathway
GO:0008593--P:regulation of Notch signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000830	Aegilops tauschii	31.25	6.00e-05	42.00
IUUC-Aml-001735	Ailuropoda melanoleuca	99.34	7.00e-159	554.00
IUUC-Aca-005007	Anolis carolinensis	81.62	0.00e+00	1001.00
IUUC-Ame-011497	Astyanax mexicanus	74.44	0.00e+00	907.00
IUUC-Bta-012612	Bos taurus	96.46	0.00e+00	1036.00
IUUC-Bdi-014427	Brachypodium distachyon	28.12	3.00e-04	40.00
IUUC-Csa-023525	Chlorocebus sabaeus	98.24	0.00e+00	1060.00
IUUC-Dre-028108	Danio rerio	82.30	6.00e-146	509.00
IUUC-Eca-033826	Equus caballus	90.77	3.00e-155	541.00
IUUC-Fca-036290	Felis catus	93.64	2.00e-156	546.00
IUUC-Gmo-039078	Gadus morhua	82.21	1.00e-156	546.00
IUUC-Gga-040162	Gallus gallus	80.23	0.00e+00	920.00
IUUC-Gac-042521	Gasterosteus aculeatus	75.16	0.00e+00	890.00
IUUC-Ggo-044598	Gorilla gorilla	87.20	0.00e+00	998.00
IUUC-Hsa-046570	Homo sapiens	97.43	0.00e+00	1046.00
IUUC-Hvu-047201	Hordeum vulgare	31.25	7.00e-05	42.00
IUUC-Loc-052134	Lepisosteus oculatus	77.13	0.00e+00	959.00
IUUC-Laf-054360	Loxodonta africana	99.40	2.00e-175	608.00
IUUC-Meu-056430	Macropus eugenii	93.11	5.00e-165	574.00
IUUC-Mmr-061378	Microcebus murinus	88.15	4.00e-149	521.00
IUUC-Mmu-064234	Mus musculus	94.90	0.00e+00	1032.00
IUUC-Mpu-066343	Mustela putorius furo	98.71	3.00e-162	564.00
IUUC-Mlu-067905	Myotis lucifugus	93.33	1.00e-161	563.00
IUUC-Nle-069498	Nomascus leucogenys	95.66	0.00e+00	1009.00
IUUC-Opr-070885	Ochotona princeps	89.30	0.00e+00	925.00
IUUC-Ont-072400	Oreochromis niloticus	74.03	0.00e+00	925.00
IUUC-Oan-073617	Ornithorhynchus anatinus	77.25	0.00e+00	677.00
IUUC-Oba-075224	Oryza barthii	27.27	3.00e-05	42.70
IUUC-Ogl-077568	Oryza glaberrima	27.27	3.00e-05	43.10
IUUC-Ogu-077958	Oryza glumaepatula	27.27	3.00e-05	43.10
IUUC-Oin-079699	Oryza indica	27.27	3.00e-05	43.10
IUUC-Ome-081380	Oryza meridionalis	27.27	3.00e-05	43.10
IUUC-Oni-082776	Oryza nivara	27.27	3.00e-05	43.10
IUUC-Opu-083671	Oryza punctata	26.36	2.00e-05	43.50
IUUC-Oru-085146	Oryza rufipogon	27.27	3.00e-05	43.10
IUUC-Osa-085571	Oryza sativa	27.27	3.00e-05	43.10
IUUC-Ola-087219	Oryzias latipes	74.33	0.00e+00	898.00
IUUC-Oga-088768	Otolemur garnettii	95.99	0.00e+00	1023.00
IUUC-Ptr-090522	Pan troglodytes	93.73	0.00e+00	988.00
IUUC-Psi-093534	Pelodiscus sinensis	88.03	2.00e-146	511.00
IUUC-Pma-094460	Petromyzon marinus	74.51	1.00e-133	469.00
IUUC-Pfo-096114	Poecilia formosa	73.42	0.00e+00	927.00
IUUC-Pab-098315	Pongo abelii	93.41	0.00e+00	977.00
IUUC-Pca-100459	Procavia capensis	95.54	2.00e-105	376.00
IUUC-Pva-102574	Pteropus vampyrus	88.16	8.00e-175	607.00
IUUC-Pte-104269	Pyrenophora teres	30.86	1.00e-03	36.60
IUUC-Pyt-104708	Pyrenophora triticirepentis	29.01	2.00e-03	36.60
IUUC-Rno-105607	Rattus norvegicus	95.06	0.00e+00	1033.00
IUUC-Sha-107129	Sarcophilus harrisii	82.55	0.00e+00	1009.00
IUUC-Sit-110693	Setaria italica	23.64	3.00e-05	43.10
IUUC-Ssc-116198	Sus scrofa	93.67	6.00e-163	567.00
IUUC-Tru-118569	Takifugu rubripes	72.88	0.00e+00	928.00
IUUC-Tni-120406	Tetraodon nigroviridis	69.92	0.00e+00	720.00
IUUC-Tae-125197	Triticum aestivum	31.25	7.00e-05	41.60
IUUC-Ttr-128583	Tursiops truncatus	94.37	0.00e+00	1007.00
IUUC-Xtr-132217	Xenopus tropicalis	78.26	0.00e+00	887.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence