iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026163

UUCD1 version

UUC-CiS-00187

Ensembl Protein ID

ENSCSAVP00000016052.1

UniProt Accession

H2ZEN6; H2ZEN6_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000009453.1	ENSCSAVT00000016232.1	ENSCSAVP00000016052.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.60e-34	114.3	276	307
UBD/Beta-Prp	2.00e-61	207.7	259	487

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           gHt++v+cl+ ++++l sGs D++ikvWD+ t
   Q: 276  GHTGPVWCLCVHGDYLFSGSSDKQIKVWDTAT 307
           8********99559***************865 PP

UBD/Beta-Prp

   S: 34   ikvwdvttg.kllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklvsGshdrtir 119
           + v+d ++  k+  ++ gh+++v++++ + d  +l +gs+D+ ikvwd   ++kc  tl+ghe  vl+l+ +   +kl sGs+d ti+
   Q: 259  VGVFDPQQIfKCKGTFVGHTGPVWCLCVHGD--YLFSGSSDKQIKVWDTAtNYKCQKTLEGHEGIVLALTAHG--NKLFSGSADCTIK 342
           5566666652457899***************..8*************877599*****************999..************* PP
   S: 120  vwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls.fdsngkelvsgsldgtvkl 206
           +w + +  +l+   + hd  v+++v  +  n+l+sGsl + +++W++  ++ + t++++ ++  +++  +  ++ +l sgs+ +t+k+
   Q: 343  IWSIANLVELN-SIAAHDNPVCTLVCTD--NMLFSGSL-KSIKVWSV--ESEIITFKQELEGLNHWVRaLVAQQDYLYSGSY-QTIKI 423
           **********9.8888998888888777..********.68****99..666888877788888888854444567777776.79*** PP
   S: 207  wdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav 272
           wd++t +c++ l+     v+s++++  ++++++g+ ++si +Wdlr+ +++ +l++h   v + av
   Q: 424  WDIRTLDCIHVLQTSGGSVYSIAVT--NHHILCGTYENSIHVWDLRTHEPVAQLSGHVGIVYALAV 487
           *************************..9***************************99766666555 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

PLVFVDTPPA QLYCKICHHV YKHPVIMSCG HSYCKRCSLS IESCPVDNKK MTSVLSNLAV 60
CEQVGALYIH CRYGCKLIND RVNEYEVNQS GCPFTVKLAE RRTHEDSCLY APISCPNNPM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACTTGTTT TTGTGGACAC ACCACCTGCT CAACTATATT GCAAGATCTG TCACCATGTA 60
TATAAACACC CAGTTATAAT GTCTTGCGGA CATTCCTACT GTAAACGATG TTCCTTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	64.20	0.00e+00	750.00
IUUC-Apl-004098	Anas platyrhynchos	64.55	0.00e+00	762.00
IUUC-Aca-004852	Anolis carolinensis	60.00	2.00e-164	570.00
IUUC-Ame-011275	Astyanax mexicanus	56.48	2.00e-156	544.00
IUUC-Bta-013153	Bos taurus	64.55	0.00e+00	758.00
IUUC-Cja-019243	Callithrix jacchus	64.18	0.00e+00	728.00
IUUC-Cfa-020036	Canis familiaris	64.55	0.00e+00	755.00
IUUC-Cpo-022194	Cavia porcellus	64.48	0.00e+00	754.00
IUUC-Csa-023363	Chlorocebus sabaeus	64.73	0.00e+00	756.00
IUUC-Cin-025279	Ciona intestinalis	89.07	0.00e+00	1047.00
IUUC-Dre-027998	Danio rerio	64.07	0.00e+00	732.00
IUUC-Dno-029356	Dasypus novemcinctus	50.00	2.00e-69	253.00
IUUC-Dor-030750	Dipodomys ordii	64.30	0.00e+00	737.00
IUUC-Eca-033671	Equus caballus	54.07	2.00e-161	561.00
IUUC-Eeu-034765	Erinaceus europaeus	74.67	1.00e-128	452.00
IUUC-Fca-035843	Felis catus	64.36	0.00e+00	753.00
IUUC-Fal-037237	Ficedula albicollis	64.36	0.00e+00	763.00
IUUC-Gmo-038779	Gadus morhua	58.58	0.00e+00	677.00
IUUC-Gga-040579	Gallus gallus	64.55	0.00e+00	761.00
IUUC-Gac-042233	Gasterosteus aculeatus	60.46	0.00e+00	718.00
IUUC-Gma-043481	Glycine max	24.71	1.00e-18	85.90
IUUC-Ggo-045147	Gorilla gorilla	64.73	0.00e+00	756.00
IUUC-Hsa-046117	Homo sapiens	64.73	0.00e+00	756.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	64.73	0.00e+00	761.00
IUUC-Lch-050593	Latimeria chalumnae	64.43	0.00e+00	738.00
IUUC-Loc-052444	Lepisosteus oculatus	63.52	0.00e+00	752.00
IUUC-Laf-053499	Loxodonta africana	64.07	0.00e+00	746.00
IUUC-Mcc-055038	Macaca mulatta	64.73	0.00e+00	756.00
IUUC-Meu-056610	Macropus eugenii	57.70	1.00e-140	491.00
IUUC-Mtr-057641	Medicago truncatula	25.50	2.00e-19	88.60
IUUC-Mga-060183	Meleagris gallopavo	64.49	0.00e+00	758.00
IUUC-Mmr-061133	Microcebus murinus	62.26	0.00e+00	690.00
IUUC-Mdo-062312	Monodelphis domestica	64.18	0.00e+00	754.00
IUUC-Mmu-063844	Mus musculus	64.73	0.00e+00	756.00
IUUC-Mac-065113	Musa acuminata	28.23	5.00e-21	94.70
IUUC-Mpu-066552	Mustela putorius furo	64.55	0.00e+00	754.00
IUUC-Mlu-067719	Myotis lucifugus	64.36	0.00e+00	729.00
IUUC-Nle-070045	Nomascus leucogenys	64.55	0.00e+00	753.00
IUUC-Opr-070927	Ochotona princeps	64.07	0.00e+00	754.00
IUUC-Ont-072680	Oreochromis niloticus	62.06	0.00e+00	741.00
IUUC-Oan-073521	Ornithorhynchus anatinus	80.00	6.00e-45	170.00
IUUC-Ola-087454	Oryzias latipes	61.70	0.00e+00	746.00
IUUC-Oga-088380	Otolemur garnettii	64.55	0.00e+00	760.00
IUUC-Oar-089558	Ovis aries	56.74	5.00e-176	609.00
IUUC-Ptr-091606	Pan troglodytes	64.73	0.00e+00	756.00
IUUC-Pan-092227	Papio anubis	64.73	0.00e+00	756.00
IUUC-Psi-093853	Pelodiscus sinensis	57.45	2.00e-174	603.00
IUUC-Pma-094541	Petromyzon marinus	54.98	2.00e-105	373.00
IUUC-Pfo-096237	Poecilia formosa	62.39	0.00e+00	746.00
IUUC-Pab-097589	Pongo abelii	64.91	0.00e+00	758.00
IUUC-Pop-099181	Populus trichocarpa	28.87	2.00e-18	84.70
IUUC-Pca-100375	Procavia capensis	63.99	0.00e+00	724.00
IUUC-Ppe-101355	Prunus persica	25.44	2.00e-17	81.60
IUUC-Pva-102434	Pteropus vampyrus	64.73	0.00e+00	757.00
IUUC-Rno-105443	Rattus norvegicus	64.73	0.00e+00	758.00
IUUC-Sha-106517	Sarcophilus harrisii	64.25	0.00e+00	751.00
IUUC-Sly-111471	Solanum lycopersicum	26.69	3.00e-18	84.70
IUUC-Stu-112183	Solanum tuberosum	25.83	6.00e-16	77.00
IUUC-Ssc-115990	Sus scrofa	64.00	0.00e+00	752.00
IUUC-Tgu-117222	Taeniopygia guttata	64.66	0.00e+00	760.00
IUUC-Tru-118392	Takifugu rubripes	62.12	0.00e+00	743.00
IUUC-Tni-120220	Tetraodon nigroviridis	61.84	0.00e+00	739.00
IUUC-Tca-121089	Theobroma cacao	26.30	2.00e-20	91.70
IUUC-Tbe-128045	Tupaia belangeri	78.12	2.00e-129	454.00
IUUC-Ttr-128203	Tursiops truncatus	61.45	0.00e+00	714.00
IUUC-Vvi-131635	Vitis vinifera	28.24	4.00e-23	100.00
IUUC-Xtr-132043	Xenopus tropicalis	64.43	0.00e+00	752.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence