iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005056

Ensembl Protein ID

ENSACAP00000008290.2

UniProt Accession

G1KHU3; G1KHU3_ANOCA

Protein Name

Coronin

Gene Name

CORO1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008365.3	ENSACAT00000008469.3	ENSACAP00000008290.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.10e-14	51.2	80	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d++++s+s D++i+vW +
   Q: 80   GHTGPVLDIDWcphNDNIIASASEDCSIMVWQI 112
           8***********9877***************86 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSFRKVVRQS KFRHVFGQPV KNDQCYDDIR VSRVTWDSTF CAVNPKFVAV IIEASGGGAF 60
MVLPLQKTGR IDKSYPTVCG HTGPVLDIDW CPHNDNIIAS ASEDCSIMVW QIPDSGLTLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGTTATGT TTATTCATAT CATGATCTGA TCACCATGCT CAATATATCC CATATGCATG 60
GGGGTATTGG GATAACGGAT ATTATGCATG GGAGTATTGG AGCCCCGGTG GCGCAGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0001725--C:stress fiber
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0090135--P:actin filament branching
GO:0051017--P:actin filament bundle assembly
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0035767--P:endothelial cell chemotaxis
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0071672--P:negative regulation of smooth muscle cell chemotaxis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:1902463--P:protein localization to cell leading edge
GO:0031529--P:ruffle organization
GO:0042060--P:wound healing

KEGG

acs:100557733

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002423	Ailuropoda melanoleuca	80.82	0.00e+00	849.00
IUUC-Apl-003861	Anas platyrhynchos	71.75	0.00e+00	767.00
IUUC-Ame-011256	Astyanax mexicanus	71.28	0.00e+00	716.00
IUUC-Bta-012984	Bos taurus	80.94	0.00e+00	852.00
IUUC-Cja-019498	Callithrix jacchus	80.41	0.00e+00	843.00
IUUC-Cfa-020937	Canis familiaris	84.81	0.00e+00	815.00
IUUC-Cpo-021866	Cavia porcellus	79.59	0.00e+00	821.00
IUUC-Csa-023561	Chlorocebus sabaeus	80.61	0.00e+00	845.00
IUUC-Cho-024687	Choloepus hoffmanni	78.72	0.00e+00	742.00
IUUC-Cin-025610	Ciona intestinalis	42.79	1.00e-53	202.00
IUUC-Dre-028124	Danio rerio	71.75	0.00e+00	773.00
IUUC-Dno-029770	Dasypus novemcinctus	77.44	0.00e+00	804.00
IUUC-Dor-030989	Dipodomys ordii	80.20	0.00e+00	833.00
IUUC-Dme-032091	Drosophila melanogaster	60.51	6.00e-150	523.00
IUUC-Ete-032839	Echinops telfairi	66.12	0.00e+00	686.00
IUUC-Eca-033901	Equus caballus	80.61	0.00e+00	830.00
IUUC-Eeu-034499	Erinaceus europaeus	71.88	1.00e-165	575.00
IUUC-Fca-036494	Felis catus	80.61	0.00e+00	827.00
IUUC-Fal-036737	Ficedula albicollis	81.15	0.00e+00	836.00
IUUC-Fox-037737	Fusarium oxysporum	41.67	8.00e-91	327.00
IUUC-Gmo-038678	Gadus morhua	71.49	0.00e+00	741.00
IUUC-Ggr-039956	Gaeumannomyces graminis	42.14	2.00e-96	346.00
IUUC-Gga-040842	Gallus gallus	71.34	0.00e+00	769.00
IUUC-Gac-041543	Gasterosteus aculeatus	71.90	0.00e+00	729.00
IUUC-Ggo-045035	Gorilla gorilla	81.02	0.00e+00	844.00
IUUC-Hsa-046154	Homo sapiens	80.82	0.00e+00	841.00
IUUC-Itr-048847	Ictidomys tridecemlineatus	80.41	0.00e+00	823.00
IUUC-Lch-050453	Latimeria chalumnae	72.73	0.00e+00	759.00
IUUC-Loc-052911	Lepisosteus oculatus	71.90	0.00e+00	758.00
IUUC-Laf-054566	Loxodonta africana	81.02	0.00e+00	829.00
IUUC-Mcc-054879	Macaca mulatta	80.41	0.00e+00	841.00
IUUC-Mpo-057410	Magnaporthe poae	42.14	4.00e-90	325.00
IUUC-Mga-060143	Meleagris gallopavo	71.49	0.00e+00	767.00
IUUC-Mmr-060910	Microcebus murinus	81.22	0.00e+00	854.00
IUUC-Mmu-063455	Mus musculus	81.06	0.00e+00	852.00
IUUC-Mpu-066350	Mustela putorius furo	81.02	0.00e+00	835.00
IUUC-Mlu-067353	Myotis lucifugus	80.57	0.00e+00	835.00
IUUC-Nle-069161	Nomascus leucogenys	81.02	0.00e+00	839.00
IUUC-Opr-071106	Ochotona princeps	79.80	0.00e+00	824.00
IUUC-Ont-072629	Oreochromis niloticus	71.40	0.00e+00	758.00
IUUC-Oan-073547	Ornithorhynchus anatinus	72.37	0.00e+00	766.00
IUUC-Ocu-074569	Oryctolagus cuniculus	71.34	0.00e+00	764.00
IUUC-Ola-086558	Oryzias latipes	71.40	0.00e+00	764.00
IUUC-Oga-088805	Otolemur garnettii	81.30	0.00e+00	850.00
IUUC-Oar-089654	Ovis aries	71.13	0.00e+00	766.00
IUUC-Ptr-091484	Pan troglodytes	81.02	0.00e+00	842.00
IUUC-Pan-091843	Papio anubis	80.20	0.00e+00	833.00
IUUC-Psi-093011	Pelodiscus sinensis	71.13	0.00e+00	759.00
IUUC-Pfo-097309	Poecilia formosa	71.49	0.00e+00	763.00
IUUC-Pab-097835	Pongo abelii	81.02	0.00e+00	843.00
IUUC-Pca-100411	Procavia capensis	72.24	0.00e+00	734.00
IUUC-Pva-102659	Pteropus vampyrus	81.22	0.00e+00	844.00
IUUC-Rno-106070	Rattus norvegicus	80.65	0.00e+00	846.00
IUUC-Sha-106609	Sarcophilus harrisii	89.01	0.00e+00	693.00
IUUC-Sar-113292	Sorex araneus	74.73	5.00e-177	613.00
IUUC-Ssc-115980	Sus scrofa	78.00	0.00e+00	824.00
IUUC-Tgu-116597	Taeniopygia guttata	71.55	0.00e+00	766.00
IUUC-Tru-118425	Takifugu rubripes	71.49	0.00e+00	757.00
IUUC-Tsy-119223	Tarsius syrichta	66.36	3.00e-175	607.00
IUUC-Tni-120610	Tetraodon nigroviridis	71.07	0.00e+00	758.00
IUUC-Tbe-127679	Tupaia belangeri	71.19	3.00e-159	554.00
IUUC-Vpa-130339	Vicugna pacos	80.78	7.00e-177	613.00
IUUC-Xtr-132873	Xenopus tropicalis	63.95	0.00e+00	679.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence