iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054281

UUCD1 version

UUC-LoA-00065

Ensembl Protein ID

ENSLAFP00000001814.2

UniProt Accession

G3SPY8; G3SPY8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000002169.2	ENSLAFT00000002169.2	ENSLAFP00000001814.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	87.17	0.00e+00	783.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MTSLSTSVQC ASSASACRLS AEHITQVRPK LPLLKILHAA GAQGEMFTVK EVMQYLGQYI 60
MMKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKEPSPLYD MLRKNLVTLA TPAADAAQTL 120

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Nucleotide Sequence
(Fasta)

ATGACGTCCC TTTCCACCTC CGTCCAGTGT GCGTCATCTG CCAGTGCTTG CAGGCTCTCT 60
GCAGAACACA TCACTCAGGT AAATCGGTCG TAGGCATTTC TGTTTTTCTT AAAATTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

KEGG

lav:100658206

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	86.79	0.00e+00	768.00
IUUC-Apl-003800	Anas platyrhynchos	58.54	7.00e-150	523.00
IUUC-Aca-004608	Anolis carolinensis	56.97	2.00e-141	495.00
IUUC-Ame-010869	Astyanax mexicanus	46.25	2.00e-105	375.00
IUUC-Bta-013287	Bos taurus	84.32	0.00e+00	819.00
IUUC-Cja-019305	Callithrix jacchus	84.73	0.00e+00	771.00
IUUC-Cfa-020393	Canis familiaris	86.99	0.00e+00	788.00
IUUC-Cpo-022166	Cavia porcellus	85.41	0.00e+00	730.00
IUUC-Csa-023654	Chlorocebus sabaeus	87.17	0.00e+00	768.00
IUUC-Cho-024403	Choloepus hoffmanni	86.52	2.00e-123	435.00
IUUC-Cin-025448	Ciona intestinalis	28.70	2.00e-21	95.90
IUUC-Dre-027754	Danio rerio	48.35	3.00e-116	411.00
IUUC-Dno-029630	Dasypus novemcinctus	85.77	0.00e+00	812.00
IUUC-Dor-031064	Dipodomys ordii	65.17	0.00e+00	630.00
IUUC-Ete-032901	Echinops telfairi	83.74	0.00e+00	815.00
IUUC-Eca-034234	Equus caballus	88.59	0.00e+00	889.00
IUUC-Eeu-035015	Erinaceus europaeus	64.02	5.00e-161	560.00
IUUC-Fca-036587	Felis catus	87.78	0.00e+00	811.00
IUUC-Fal-036906	Ficedula albicollis	50.31	7.00e-132	463.00
IUUC-Gmo-038646	Gadus morhua	45.40	2.00e-97	348.00
IUUC-Gga-040124	Gallus gallus	57.77	2.00e-114	405.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.06	1.00e-106	379.00
IUUC-Ggo-045505	Gorilla gorilla	86.97	0.00e+00	785.00
IUUC-Hsa-046950	Homo sapiens	87.17	0.00e+00	788.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	86.15	0.00e+00	798.00
IUUC-Lch-050141	Latimeria chalumnae	52.87	2.00e-123	435.00
IUUC-Loc-051921	Lepisosteus oculatus	50.30	3.00e-115	408.00
IUUC-Mcc-055462	Macaca mulatta	83.13	0.00e+00	714.00
IUUC-Meu-056294	Macropus eugenii	70.40	3.00e-143	501.00
IUUC-Mga-059924	Meleagris gallopavo	58.42	1.00e-162	565.00
IUUC-Mmr-061428	Microcebus murinus	86.15	0.00e+00	828.00
IUUC-Mdo-062643	Monodelphis domestica	74.45	0.00e+00	715.00
IUUC-Mmu-063229	Mus musculus	78.82	0.00e+00	754.00
IUUC-Mpu-065782	Mustela putorius furo	84.99	0.00e+00	775.00
IUUC-Mlu-068105	Myotis lucifugus	77.24	0.00e+00	736.00
IUUC-Nle-069549	Nomascus leucogenys	87.17	0.00e+00	788.00
IUUC-Opr-070568	Ochotona princeps	85.16	0.00e+00	745.00
IUUC-Ont-072276	Oreochromis niloticus	47.39	1.00e-116	413.00
IUUC-Oan-072787	Ornithorhynchus anatinus	73.08	0.00e+00	666.00
IUUC-Ocu-074912	Oryctolagus cuniculus	86.35	0.00e+00	799.00
IUUC-Ola-087037	Oryzias latipes	46.18	8.00e-99	353.00
IUUC-Oga-088953	Otolemur garnettii	83.03	0.00e+00	772.00
IUUC-Oar-089202	Ovis aries	85.54	0.00e+00	831.00
IUUC-Ptr-090964	Pan troglodytes	87.17	0.00e+00	788.00
IUUC-Pan-091975	Papio anubis	86.97	0.00e+00	781.00
IUUC-Psi-093558	Pelodiscus sinensis	60.90	1.00e-160	559.00
IUUC-Pma-094500	Petromyzon marinus	30.93	4.00e-21	94.40
IUUC-Pfo-096454	Poecilia formosa	47.84	8.00e-113	400.00
IUUC-Pab-098123	Pongo abelii	86.97	0.00e+00	789.00
IUUC-Pca-101112	Procavia capensis	84.35	0.00e+00	795.00
IUUC-Pva-103098	Pteropus vampyrus	76.58	0.00e+00	725.00
IUUC-Rno-105930	Rattus norvegicus	78.25	0.00e+00	723.00
IUUC-Sha-107512	Sarcophilus harrisii	71.75	0.00e+00	632.00
IUUC-Sar-113584	Sorex araneus	78.82	0.00e+00	704.00
IUUC-Tgu-116766	Taeniopygia guttata	55.14	1.00e-99	355.00
IUUC-Tru-117829	Takifugu rubripes	48.97	2.00e-116	412.00
IUUC-Tsy-119268	Tarsius syrichta	72.71	0.00e+00	646.00
IUUC-Tni-120204	Tetraodon nigroviridis	45.31	3.00e-106	378.00
IUUC-Tbe-127840	Tupaia belangeri	80.98	2.00e-122	432.00
IUUC-Ttr-128863	Tursiops truncatus	84.32	0.00e+00	792.00
IUUC-Vpa-130718	Vicugna pacos	87.53	0.00e+00	779.00
IUUC-Xtr-132320	Xenopus tropicalis	45.91	1.00e-89	323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence