iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010660

Ensembl Protein ID

ENSAMXP00000007921.1

UniProt Accession

W5KK09; W5KK09_ASTMX

Genbank Protein ID

ENSAMXP00000007921

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01092423

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000007707.1	ENSAMXT00000007921.1	ENSAMXP00000007921.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.10e-87	293.9	11	311

Active Site

Position(s)	Description	Evidence
279	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 40   dlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgk..............klsledleevd 114
            +g+f+y ++++++++ + +      ++ + F+++G l+g+a++++  ld+++++++yk+ll+                l+l+dl++++
   Q: 11   ITGMFTYVKDSQCHWFSSWKC-----DNCSEFRLVGALMGLAVYNSITLDIRFPPCVYKKLLTPpiipcdpdapvgmaTLTLDDLQQIM 94
           5799*****999999966655.....7899*******************************999666555555555555********** PP
   S: 115  pelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevipl 203
           p+l++ l e++++ e ++ee  +  tf+v +e+lg +k+++LkpgG++ipVtn+N++eYv+l++++ l+++i +q++af+ Gf++v+  
   Q: 95   PDLAHGLGELLSY-EGNVEED-FYTTFQVFQEELGVVKSYNLKPGGDKIPVTNQNRREYVQLYIDFLLNKSIYRQFAAFYHGFHSVCAS 181
           ************9.6788885.******************************************************************* PP
   S: 204  ellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk. 291
           + l l+++ee+e+l+cG++++d+++l++ ++y+ gy++++p+i+ Fw+v+ +f  e +k++L+F+Tgs+r+P+gG+a+l+   f i+k 
   Q: 182  NALMLLRPEEVEILVCGNPNLDMSSLQRVAQYE-GYSKTDPTIRAFWDVVLGFPLELQKRMLHFTTGSDRVPVGGMADLN---FKISKi 266
           ********************************5.5*********************************************...899998 PP
   S: 292  dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           d s+d+lP s+TCfn+++LP+Y+sk++l++kL++Ai++++gF+l+
   Q: 267  DVSTDWLPVSHTCFNQICLPPYKSKKELRQKLTIAISNAEGFGLE 311
           99****************************************985 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MKCFFFLCVS ITGMFTYVKD SQCHWFSSWK CDNCSEFRLV GALMGLAVYN SITLDIRFPP 60
CVYKKLLTPP IIPCDPDAPV GMATLTLDDL QQIMPDLAHG LGELLSYEGN VEEDFYTTFQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCACAATT TGCTCTATAA TCAGTGGCTT TTTTGATTAG TGTGTTGTCA GAAAATGGTG 60
TGTAGCAGTC CAACAACAGC CACTGCAGGA AAAGTCACTT TTTTTAAACC TTTTCAAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	82.94	2.00e-153	536.00
IUUC-Apl-003589	Anas platyrhynchos	82.94	5.00e-152	531.00
IUUC-Aca-004350	Anolis carolinensis	80.94	1.00e-149	523.00
IUUC-Bta-012945	Bos taurus	82.94	1.00e-153	536.00
IUUC-Cja-019263	Callithrix jacchus	81.94	1.00e-151	530.00
IUUC-Cfa-020486	Canis familiaris	83.28	9.00e-154	536.00
IUUC-Cpo-021755	Cavia porcellus	82.61	4.00e-153	535.00
IUUC-Csa-023814	Chlorocebus sabaeus	81.92	1.00e-130	460.00
IUUC-Cho-024980	Choloepus hoffmanni	61.54	2.00e-102	367.00
IUUC-Dre-028551	Danio rerio	94.98	3.00e-173	602.00
IUUC-Dno-029497	Dasypus novemcinctus	82.61	4.00e-152	531.00
IUUC-Dor-030867	Dipodomys ordii	75.59	3.00e-136	478.00
IUUC-Ete-032902	Echinops telfairi	73.91	9.00e-135	474.00
IUUC-Eca-033678	Equus caballus	82.61	1.00e-153	536.00
IUUC-Eeu-035262	Erinaceus europaeus	69.23	1.00e-121	430.00
IUUC-Fca-035590	Felis catus	82.94	7.00e-154	537.00
IUUC-Fal-037123	Ficedula albicollis	76.32	2.00e-136	479.00
IUUC-Gmo-039553	Gadus morhua	77.93	3.00e-146	511.00
IUUC-Gga-040406	Gallus gallus	82.61	1.00e-151	530.00
IUUC-Gac-042141	Gasterosteus aculeatus	83.61	2.00e-153	536.00
IUUC-Ggo-045504	Gorilla gorilla	81.61	7.00e-150	524.00
IUUC-Hsa-045786	Homo sapiens	81.61	9.00e-150	524.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	81.46	1.00e-152	533.00
IUUC-Lch-049824	Latimeria chalumnae	80.77	2.00e-129	456.00
IUUC-Loc-052173	Lepisosteus oculatus	85.62	1.00e-159	556.00
IUUC-Laf-054017	Loxodonta africana	81.61	4.00e-152	531.00
IUUC-Mcc-055713	Macaca mulatta	81.94	1.00e-151	530.00
IUUC-Meu-056212	Macropus eugenii	63.76	8.00e-97	347.00
IUUC-Mga-059884	Meleagris gallopavo	82.94	4.00e-153	535.00
IUUC-Mmr-061344	Microcebus murinus	81.61	3.00e-151	528.00
IUUC-Mdo-062653	Monodelphis domestica	80.94	2.00e-150	526.00
IUUC-Mmu-063775	Mus musculus	82.94	4.00e-153	535.00
IUUC-Mpu-066069	Mustela putorius furo	82.94	3.00e-153	535.00
IUUC-Mlu-067925	Myotis lucifugus	82.61	3.00e-154	538.00
IUUC-Nle-070046	Nomascus leucogenys	81.27	2.00e-149	523.00
IUUC-Opr-071085	Ochotona princeps	67.45	5.00e-116	412.00
IUUC-Ont-072126	Oreochromis niloticus	84.28	7.00e-157	547.00
IUUC-Oan-072933	Ornithorhynchus anatinus	80.27	2.00e-147	516.00
IUUC-Ocu-073800	Oryctolagus cuniculus	82.27	2.00e-152	532.00
IUUC-Ola-086988	Oryzias latipes	81.94	4.00e-153	535.00
IUUC-Oga-088117	Otolemur garnettii	81.61	2.00e-150	525.00
IUUC-Oar-089371	Ovis aries	82.94	4.00e-153	535.00
IUUC-Ptr-090551	Pan troglodytes	81.61	5.00e-150	525.00
IUUC-Pan-092067	Papio anubis	81.94	2.00e-151	530.00
IUUC-Psi-092963	Pelodiscus sinensis	82.27	3.00e-151	528.00
IUUC-Pfo-096562	Poecilia formosa	82.27	2.00e-152	533.00
IUUC-Pab-098680	Pongo abelii	81.61	5.00e-150	525.00
IUUC-Pca-100986	Procavia capensis	69.77	2.00e-105	376.00
IUUC-Pva-102219	Pteropus vampyrus	76.06	3.00e-117	416.00
IUUC-Rno-105270	Rattus norvegicus	83.28	1.00e-152	533.00
IUUC-Sha-106819	Sarcophilus harrisii	82.27	2.00e-152	533.00
IUUC-Sar-113134	Sorex araneus	76.59	4.00e-141	495.00
IUUC-Ssc-115441	Sus scrofa	82.61	3.00e-153	535.00
IUUC-Tgu-117166	Taeniopygia guttata	82.27	1.00e-151	530.00
IUUC-Tsy-118898	Tarsius syrichta	67.55	5.00e-115	408.00
IUUC-Tni-119828	Tetraodon nigroviridis	79.50	4.00e-79	286.00
IUUC-Tbe-127292	Tupaia belangeri	68.56	2.00e-118	419.00
IUUC-Ttr-128352	Tursiops truncatus	75.59	7.00e-134	471.00
IUUC-Vpa-130218	Vicugna pacos	80.95	2.00e-59	224.00
IUUC-Xtr-132594	Xenopus tropicalis	70.86	1.00e-122	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence