iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071920

Ensembl Protein ID

ENSONIP00000022857.1

UniProt Accession

I3KP12; I3KP12_ORENI

Genbank Protein ID

ENSONIP00000022857

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01018910

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000018141.1	ENSONIT00000022877.1	ENSONIP00000022857.1
ENSONIG00000018141.1	ENSONIT00000022878.1	ENSONIP00000022858.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-91	308.0	9	644

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           GlkN+gNtC+mN+v+QcLsn+  l+e+l     e+ +    ++  ge++++l++l+++lw+ + +     e++++++k+a++f+g++q+
   Q: 9    GLKNHGNTCFMNAVVQCLSNTDLLAEYLGL---EQYKS---QTARGEVTEQLASLVRALWTLEYTPQLSVEFKSIVAKYASQFRGNSQH 91
           9**************************988...33332...46789******************************************* PP
   S: 91   DaqEflaflldqleeel.kk.......eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
           Da Efl +lld+++e+  ++        +  p + +++ d+ ++++ a+ ++++  +s++++ Fq q++s+++c++c ++s++++pfl 
   Q: 92   DALEFLLWLLDRVHEDDlHEggwrppvFEPLPPKGASSLDNASSPSVASIQQPRGRHSFVHEHFQAQYRSSLTCPHCLKQSNTFDPFLC 180
           **************975255999999877778888888888999999****************************************** PP
   S: 172  lslpvpgkeetkke........................................................................... 185
           +slp+p ++++ +                                                                            
   Q: 181  ISLPIPLRQTR-PMcvtlvfntkgqrhlrvglavplfgslsslralvaaegnispdqvilvelystgfqrsfsdeedltaiadsdvvya 268
           *******9966.4469************************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 269  fqapslssrggsaqhsgyhhslpsspyafmagpdgqrlppsgtlsseylnqgnskvlllicntagsasqavrfgppfliledrsiswdq 357
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 358  lhqsilsklyylmlngsqaqsagalfkirvvggsaaysylspqdgrplyhpavdralkfcgpggpphvklviewepstkeclfgsiqee 446
           ***************************************************************************************** PP
   S: 186  .....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkv 253
                                +l++c++ +tkee+l  +++++c++ck++q+   k++l++lP++LilhLkRf  ++ +++r+k+++ v
   Q: 447  vvkdaesvrnqqqqhlqqhscTLDECFKLYTKEEQLAPDDAWKCPHCKQLQQGMVKMSLWTLPDILILHLKRF--RQVGERRNKLSTLV 533
           *************************************************************************..9999********** PP
   S: 254  efple.Ldlspfctspeekqke...........................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDsk 313
            fpl+ Ld++p++++++++ k+                           +  Y+L+av++H+G++++GHY+ay++n  +g+W+ +dDs+
   Q: 534  RFPLTgLDMAPHVVKRSQSMKNlnmgpsppswkqhsgqphqaadmmlphEFLYDLYAVCNHHGGMHGGHYTAYCRNsVDGQWYSYDDSS 622
           ***************999998899****************************************************55777******** PP
   S: 314  VtevkeeevleetgstaYvlfYkrr 338
           V  v+ eev++   + aY+lfY+rr
   Q: 623  VDLVQDEEVCT---RGAYILFYQRR 644
           ***********...*********96 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

GDKTPGVLGL KNHGNTCFMN AVVQCLSNTD LLAEYLGLEQ YKSQTARGEV TEQLASLVRA 60
LWTLEYTPQL SVEFKSIVAK YASQFRGNSQ HDALEFLLWL LDRVHEDDLH EGGWRPPVFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGACAAGA CCCCGGGAGT GCTGGGACTG AAGAACCACG GCAACACCTG TTTCATGAAC 60
GCCGTGGTTC AGTGCCTCAG CAACACGGAC CTGCTCGCCG AATACCTCGG GTTGGAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	46.92	0.00e+00	755.00
IUUC-Aca-004436	Anolis carolinensis	53.14	0.00e+00	796.00
IUUC-Ame-011153	Astyanax mexicanus	59.21	0.00e+00	1109.00
IUUC-Bta-013560	Bos taurus	52.01	0.00e+00	902.00
IUUC-Cja-018737	Callithrix jacchus	52.47	0.00e+00	888.00
IUUC-Cfa-020347	Canis familiaris	48.58	0.00e+00	821.00
IUUC-Csa-023656	Chlorocebus sabaeus	52.79	0.00e+00	919.00
IUUC-Cho-024864	Choloepus hoffmanni	50.90	1.00e-159	556.00
IUUC-Dre-028066	Danio rerio	61.58	0.00e+00	1206.00
IUUC-Dno-028855	Dasypus novemcinctus	57.82	0.00e+00	793.00
IUUC-Dor-030475	Dipodomys ordii	63.86	2.00e-136	481.00
IUUC-Dme-032088	Drosophila melanogaster	37.06	1.00e-109	391.00
IUUC-Eca-034147	Equus caballus	59.69	0.00e+00	851.00
IUUC-Fca-036550	Felis catus	46.21	0.00e+00	656.00
IUUC-Gmo-038903	Gadus morhua	58.49	0.00e+00	810.00
IUUC-Gac-042087	Gasterosteus aculeatus	72.34	0.00e+00	1329.00
IUUC-Ggo-045171	Gorilla gorilla	52.84	0.00e+00	920.00
IUUC-Hsa-045961	Homo sapiens	52.84	0.00e+00	924.00
IUUC-Loc-052852	Lepisosteus oculatus	63.51	0.00e+00	1202.00
IUUC-Laf-054033	Loxodonta africana	49.69	0.00e+00	832.00
IUUC-Mcc-055431	Macaca mulatta	52.66	0.00e+00	923.00
IUUC-Mmr-061035	Microcebus murinus	51.37	0.00e+00	882.00
IUUC-Mdo-062172	Monodelphis domestica	56.93	0.00e+00	773.00
IUUC-Mmu-063966	Mus musculus	59.69	0.00e+00	849.00
IUUC-Mpu-066307	Mustela putorius furo	48.09	0.00e+00	782.00
IUUC-Nle-070172	Nomascus leucogenys	53.16	0.00e+00	924.00
IUUC-Opr-070499	Ochotona princeps	62.23	0.00e+00	744.00
IUUC-Ocu-074014	Oryctolagus cuniculus	60.52	0.00e+00	751.00
IUUC-Ola-086360	Oryzias latipes	70.33	0.00e+00	1352.00
IUUC-Oga-088202	Otolemur garnettii	51.08	0.00e+00	879.00
IUUC-Oar-089819	Ovis aries	50.23	0.00e+00	832.00
IUUC-Ptr-091076	Pan troglodytes	52.84	0.00e+00	924.00
IUUC-Pan-092248	Papio anubis	52.84	0.00e+00	919.00
IUUC-Pfo-096534	Poecilia formosa	72.03	0.00e+00	1309.00
IUUC-Pab-098453	Pongo abelii	51.90	0.00e+00	872.00
IUUC-Pca-100290	Procavia capensis	49.18	4.00e-88	319.00
IUUC-Pva-102317	Pteropus vampyrus	44.96	0.00e+00	706.00
IUUC-Rno-104948	Rattus norvegicus	58.49	0.00e+00	764.00
IUUC-Sha-106558	Sarcophilus harrisii	47.17	0.00e+00	850.00
IUUC-Sar-113105	Sorex araneus	51.80	2.00e-170	593.00
IUUC-Ssc-115312	Sus scrofa	51.50	0.00e+00	895.00
IUUC-Tru-117995	Takifugu rubripes	70.96	0.00e+00	1347.00
IUUC-Tni-120517	Tetraodon nigroviridis	67.36	0.00e+00	1248.00
IUUC-Ttr-128829	Tursiops truncatus	45.78	0.00e+00	740.00
IUUC-Vpa-130306	Vicugna pacos	54.35	2.00e-108	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence